List of works - Ronen Marmorstein

A Tight Junction-Associated Merlin-Angiomotin Complex Mediates Merlin's Regulation of Mitogenic Signaling and Tumor Suppressive Functions ⬇️

scientific article published on April 12, 2011

Chemically Linked Vemurafenib Inhibitors Promote an Inactive BRAFV600E Conformation

scientific article

Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex

scientific article

Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation

scientific article (publication date: 4 March 2003)

Crystal structure of the stress-inducible human heat shock protein 70 substrate-binding domain in complex with peptide substrate

scientific article published in 2014

FRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated Schwannomas

scientific article

Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP

scientific article

Identification of a Novel Family of BRAF V600E Inhibitors

scientific article

Implications for the evolution of eukaryotic amino-terminal acetyltransferase (NAT) enzymes from the structure of an archaeal ortholog

scientific article

Inhibition of Epstein-Barr virus OriP function by tankyrase, a telomere-associated poly-ADP ribose polymerase that binds and modifies EBNA1

scientific article

Molecular Basis for Bre5 Cofactor Recognition by the Ubp3 Deubiquitylating Enzyme

scientific article

Molecular Basis for Oligomeric-DNA Binding and Episome Maintenance by KSHV LANA

scientific article

Molecular basis for Gcn5/PCAF histone acetyltransferase selectivity for histone and nonhistone substrates

scientific article

Molecular basis for N-terminal acetylation by the heterodimeric NatA complex

scientific article

Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification

scientific article

Structural Basis for Dimerization in DNA Recognition by Gal4

scientific article

Structural Basis for Histone and Phosphohistone Binding by the GCN5 Histone Acetyltransferase ⬇️

scientific article published on August 1, 2003

Structural Basis for Nicotinamide Inhibition and Base Exchange in Sir2 Enzymes

scientific article

Structural Basis for Ubiquitin Recognition by the Otu1 Ovarian Tumor Domain Protein

scientific article

Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases

scientific article

Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors

scientific article

Structure and Biochemical Characterization of Protein Acetyltransferase from Sulfolobus solfataricus

scientific article

Structure and autoregulation of the yeast Hst2 homolog of Sir2 ⬇️

scientific article published on September 21, 2003

Structure and mechanism of non-histone protein acetyltransferase enzymes

scientific article

Structure of Vps75 and implications for histone chaperone function

scientific article

Structure of a Sir2 substrate, Alba, reveals a mechanism for deacetylation-induced enhancement of DNA binding

scientific article (publication date: 11 July 2003)

Structure of a Ternary Naa50p (NAT5/SAN) N-terminal Acetyltransferase Complex Reveals the Molecular Basis for Substrate-specific Acetylation

scientific article

Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly

scientific article

Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

scientific article

Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation ⬇️

scientific article published on January 20, 2011

Structure of the Yeast Hst2 Protein Deacetylase in Ternary Complex with 2′-O-Acetyl ADP Ribose and Histone Peptide ⬇️

scientific article published on November 1, 2003

Structure of the human Papillomavirus E7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressor

scientific article

Structure of the p300 Histone Acetyltransferase Bound to Acetyl-Coenzyme A and Its Analogues

scientific article

Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor

scientific article

Structure-Based Design of an Organoruthenium Phosphatidyl-inositol-3-kinase Inhibitor Reveals a Switch Governing Lipid Kinase Potency and Selectivity

scientific article

Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity

scientific article

Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes

scientific article

The Art of Filling Protein Pockets Efficiently with Octahedral Metal Complexes

scientific article

The Crystal Structure of BRAF in Complex with an Organoruthenium Inhibitor Reveals a Mechanism for Inhibition of an Active Form of BRAF Kinase

scientific article

The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate

scientific article

The human monocytic leukemia zinc finger histone acetyltransferase domain contains DNA-binding activity implicated in chromatin targeting

scientific article

The structural basis of protein acetylation by the p300/CBP transcriptional coactivator

scientific article

The structurally disordered KRAB repression domain is incorporated into a protease resistant core upon binding to KAP-1-RBCC domain

scientific article

List of works by Ronen Marmorstein

A Tight Junction-Associated Merlin-Angiomotin Complex Mediates Merlin's Regulation of Mitogenic Signaling and Tumor Suppressive Functions ⬇️

Chemically Linked Vemurafenib Inhibitors Promote an Inactive BRAFV600E Conformation

Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex

Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation

Crystal structure of the stress-inducible human heat shock protein 70 substrate-binding domain in complex with peptide substrate

FRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated Schwannomas

Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP

Identification of a Novel Family of BRAF V600E Inhibitors

Implications for the evolution of eukaryotic amino-terminal acetyltransferase (NAT) enzymes from the structure of an archaeal ortholog

Inhibition of Epstein-Barr virus OriP function by tankyrase, a telomere-associated poly-ADP ribose polymerase that binds and modifies EBNA1

Molecular Basis for Bre5 Cofactor Recognition by the Ubp3 Deubiquitylating Enzyme

Molecular Basis for Oligomeric-DNA Binding and Episome Maintenance by KSHV LANA

Molecular basis for Gcn5/PCAF histone acetyltransferase selectivity for histone and nonhistone substrates

Molecular basis for N-terminal acetylation by the heterodimeric NatA complex

Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification

Structural Basis for Dimerization in DNA Recognition by Gal4

Structural Basis for Histone and Phosphohistone Binding by the GCN5 Histone Acetyltransferase ⬇️

Structural Basis for Nicotinamide Inhibition and Base Exchange in Sir2 Enzymes

Structural Basis for Ubiquitin Recognition by the Otu1 Ovarian Tumor Domain Protein

Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases

Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors

Structure and Biochemical Characterization of Protein Acetyltransferase from Sulfolobus solfataricus

Structure and autoregulation of the yeast Hst2 homolog of Sir2 ⬇️

Structure and mechanism of non-histone protein acetyltransferase enzymes

Structure of Vps75 and implications for histone chaperone function

Structure of a Sir2 substrate, Alba, reveals a mechanism for deacetylation-induced enhancement of DNA binding

Structure of a Ternary Naa50p (NAT5/SAN) N-terminal Acetyltransferase Complex Reveals the Molecular Basis for Substrate-specific Acetylation

Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly

Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation ⬇️

Structure of the Yeast Hst2 Protein Deacetylase in Ternary Complex with 2′-O-Acetyl ADP Ribose and Histone Peptide ⬇️

Structure of the human Papillomavirus E7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressor

Structure of the p300 Histone Acetyltransferase Bound to Acetyl-Coenzyme A and Its Analogues

Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor

Structure-Based Design of an Organoruthenium Phosphatidyl-inositol-3-kinase Inhibitor Reveals a Switch Governing Lipid Kinase Potency and Selectivity

Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity

Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes

The Art of Filling Protein Pockets Efficiently with Octahedral Metal Complexes

The Crystal Structure of BRAF in Complex with an Organoruthenium Inhibitor Reveals a Mechanism for Inhibition of an Active Form of BRAF Kinase

The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate

The human monocytic leukemia zinc finger histone acetyltransferase domain contains DNA-binding activity implicated in chromatin targeting

The structural basis of protein acetylation by the p300/CBP transcriptional coactivator

The structurally disordered KRAB repression domain is incorporated into a protease resistant core upon binding to KAP-1-RBCC domain