Search filters

List of works by Claudia Binda

2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1

scientific article

4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity

scientific article

8 Demethylation pathways for histone methyllysine residues

scientific article published in 2006

A 30 Å long U-shaped catalytic tunnel in the crystal structure of polyamine oxidase

A highly specific mechanism of histone H3-K4 recognition by histone demethylase LSD1.

scientific article published on 20 September 2006

A novel mammalian flavin-dependent histone demethylase

scientific journal article

Alternative splicing of the histone demethylase LSD1/KDM1 contributes to the modulation of neurite morphogenesis in the mammalian nervous system

scientific article

An unprecedented NADPH domain conformation in lysine monooxygenase NbtG provides insights into uncoupling of oxygen consumption from substrate hydroxylation

scientific article published on 23 March 2015

Binding of rasagiline-related inhibitors to human monoamine oxidases: a kinetic and crystallographic analysis

scientific article

Biocatalytic Properties and Structural Analysis of Eugenol Oxidase from Rhodococcus jostii RHA1: A Versatile Oxidative Biocatalyst

scientific article

Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2

scientific article

Cross-talk and ammonia channeling between active centers in the unexpected domain arrangement of glutamate synthase

scientific article

Crystal structure of human monoamine oxidase B, a drug target enzyme monotopically inserted into the mitochondrial outer membrane

scientific article published on April 2004

Crystal structures of monoamine oxidase B in complex with four inhibitors of the N-propargylaminoindan class

scientific article

Crystallization and preliminary X-ray analysis of polyamine oxidase from Zea mays L

scientific article published on 01 November 1998

Crystallographic snapshots of UDP-glucuronic acid 4-epimeraseligand binding, rotation and reduction

scientific article published on 13 July 2020

Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors

scientific article published on 14 February 2005

Functional role of the "aromatic cage" in human monoamine oxidase B: structures and catalytic properties of Tyr435 mutant proteins

scientific article published in April 2006

Histone demethylation catalysed by LSD1 is a flavin-dependent oxidative process

scientific article published in April 2005

Human histone demethylase LSD1 reads the histone code

scientific article

Inactivation of purified human recombinant monoamine oxidases A and B by rasagiline and its analogues

scientific article published in March 2004

Insights into the mode of inhibition of human mitochondrial monoamine oxidase B from high-resolution crystal structures

scientific article

Interactions of Monoamine Oxidases with the Antiepileptic Drug Zonisamide: Specificity of Inhibition and Structure of the Human Monoamine Oxidase B Complex

scientific article

Kinetic and structural analysis of the irreversible inhibition of human monoamine oxidases by ASS234, a multi-target compound designed for use in Alzheimer's disease

scientific article

LSD1: oxidative chemistry for multifaceted functions in chromatin regulation

scientific article published on 17 March 2008

Lights and shadows on monoamine oxidase inhibition in neuroprotective pharmacological therapies

scientific article

Molecular Insights into Human Monoamine Oxidase B Inhibition by the Glitazone Antidiabetes Drugs

scientific article

Molecular Mimicry and Ligand Recognition in Binding and Catalysis by the Histone Demethylase LSD1-CoREST Complex

scientific article

Molecular and mechanistic properties of the membrane-bound mitochondrial monoamine oxidases

scientific article

New insights into the structures and functions of human monoamine oxidases A and B

New roles of flavoproteins in molecular cell biology: histone demethylase LSD1 and chromatin

scientific article published on 14 July 2009

Polystyrene microbridges used in sitting-drop crystallization release 1,4-diphenyl-2-butene, a novel inhibitor of human MAO B.

scientific article

Potentiation of Ligand Binding through Cooperative Effects in Monoamine Oxidase B

scientific article

Stereoselective Activity of 1-Propargyl-4-styrylpiperidine-like Analogues That Can Discriminate between Monoamine Oxidase Isoforms A and B

scientific article published on 22 January 2020

Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis

scientific article

Structural and Mechanistic Studies of Mofegiline Inhibition of Recombinant Human Monoamine Oxidase B ∥

scientific article

Structural and mechanistic studies of arylalkylhydrazine inhibition of human monoamine oxidases A and B

scientific article

Structural bases for inhibitor binding and catalysis in polyamine oxidase

scientific article

Structural basis of LSD1-CoREST selectivity in histone H3 recognition

scientific article

Structural insights into the mechanism of amine oxidation by monoamine oxidases A and B

scientific article

Structural properties of human monoamine oxidases A and B

scientific article

Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders

scientific article

Structure-Based Enzyme Tailoring of 5-Hydroxymethylfurfural Oxidase

article published in 2015

Structure-based engineering of Phanerochaete chrysosporium alcohol oxidase for enhanced oxidative power towards glycerol

scientific article published in 2018

Structure-function relationships in flavoenzyme-dependent amine oxidations: a comparison of polyamine oxidase and monoamine oxidase

scientific article

Structures of human monoamine oxidase B complexes with selective noncovalent inhibitors: safinamide and coumarin analogs

scientific article

The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis

scientific article published on 14 September 2013

The FAD binding sites of human monoamine oxidases A and B

scientific article (publication date: 2004)

The structure of monoamine oxidases: past, present, and future

The ‘gating’ residues Ile199 and Tyr326 in human monoamine oxidase B function in substrate and inhibitor recognition

scientific article

Three-dimensional structure of human monoamine oxidase A (MAO A): relation to the structures of rat MAO A and human MAO B

scientific article

Tight-Binding Inhibition of Human Monoamine Oxidase B by Chromone Analogs: A Kinetic, Crystallographic, and Biological Analysis.

scientific article published on 12 April 2018

Paulina is supported by:

About Paulina

Help