List of works - Duilio Cascio

A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis

scientific article

Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED.

scientific article published on 19 September 2016

An approach to crystallizing proteins by metal-mediated synthetic symmetrization

scientific article

Atomic Structures Suggest Determinants of Transmission Barriers in Mammalian Prion Disease

scientific article

Atomic View of a Toxic Amyloid Small Oligomer

scientific article

Atomic structure of the cross-β spine of islet amyloid polypeptide (amylin)

scientific article

Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity

scientific article published on 03 January 2017

Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.

scientific article published on 13 February 2017

Bacterial microcompartment shells of diverse functional types possess pentameric vertex proteins

scientific article

Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3

scientific article

Comparison of Two Yeast MnSODs: Mitochondrial Saccharomyces cerevisiae versus Cytosolic Candida albicans

scientific article

Control of DNA minor groove width and Fis protein binding by the purine 2-amino group ⬇️

scientific article published on May 9, 2013

Crystal structure of a major secreted protein of Mycobacterium tuberculosis-MPT63 at 1.5-Å resolution

scientific article

Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function

scientific article

Crystallographic Studies of Prion Protein (PrP) Segments Suggest How Structural Changes Encoded by Polymorphism at Residue 129 Modulate Susceptibility to Human Prion Disease

scientific article

De novo phasing with X-ray laser reveals mosquito larvicide BinAB structure

scientific article

Discovery of a Thermophilic Protein Complex Stabilized by Topologically Interlinked Chains

scientific article

Fis Targets Assembly of the Xis Nucleoprotein Filament to Promote Excisive Recombination by Phage Lambda

scientific article

Granulysin crystal structure and a structure-derived lytic mechanism

scientific article

Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions

scientific article

Low-complexity domains adhere by reversible amyloid-like interactions between kinked β-sheets

MicroED Structures from Micrometer Thick Protein Crystals

article published in 2017

Molecular basis for amyloid- polymorphism

scientific article

Molecular mechanisms for protein-encoded inheritance

scientific article

Regulation of clathrin adaptor function in endocytosis: novel role for the SAM domain

scientific article

Site-directed spin labeling of a genetically encoded unnatural amino acid

scientific article

Six-coordinate manganese(3+) in catalysis by yeast manganese superoxide dismutase ⬇️

scientific article published on August 20, 2012

Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65

scientific article

Structural Insight into the Mechanisms of Transport across the Salmonella enterica Pdu Microcompartment Shell

scientific article

Structural and EPR characterization of the soluble form of cytochrome c-550 and of the psbV2 gene product from the cyanobacterium Thermosynechococcus elongatus

scientific article

Structural and Functional Studies of γ-Carboxyglutamic Acid Domains of Factor VIIa and Activated Protein C: Role of Magnesium at Physiological Calcium ⬇️

scientific article published on February 20, 2013

Structural determinants of nitroxide motion in spin-labeled proteins: Solvent-exposed sites in helix B of T4 lysozyme

scientific article

Structural determinants of nitroxide motion in spin-labeled proteins: Tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme

scientific article

Structural origin of weakly ordered nitroxide motion in spin-labeled proteins

scientific article

Structure and Functional Studies of the CS Domain of the Essential H/ACA Ribonucleoparticle Assembly Protein SHQ1

scientific article

Structure and Identification of a Pterin Dehydratase-like Protein as a Ribulose-bisphosphate Carboxylase/Oxygenase (RuBisCO) Assembly Factor in the α-Carboxysome

scientific article

Structure and proposed activity of a member of the VapBC family of toxin-antitoxin systems. VapBC-5 from Mycobacterium tuberculosis

scientific article

Structure of Dihydromethanopterin Reductase, a Cubic Protein Cage for Redox Transfer

scientific article

Structure of a 16-nm cage designed by using protein oligomers

scientific article

Structure of a Nudix protein from Pyrobaculum aerophilum reveals a dimer with two intersubunit beta-sheets

scientific article

Structure of the cooperative Xis-DNA complex reveals a micronucleoprotein filament that regulates phage lambda intasome assembly

scientific article

Structure of the dimerization domain of DiGeorge Critical Region 8

scientific article

Structure of the toxic core of α-synuclein from invisible crystals

scientific article published on 9 September 2015

Structures and Functional Implications of an AMP-Binding Cystathionine β-Synthase Domain Protein from a Hyperthermophilic Archaeon

scientific article

Structures of segments of α-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation

scientific article

Synthetic symmetrization in the crystallization and structure determination of CelA fromThermotoga maritima

scientific article

The 1.6 A resolution structure of Fe-superoxide dismutase from the thermophilic cyanobacterium Thermosynechococcus elongatus

scientific article

The Crystal Structure of a Sodium Galactose Transporter Reveals Mechanistic Insights into Na+/Sugar Symport

scientific article

The Role of Cys-298 in Aldose Reductase Function ⬇️

scientific article published on November 17, 2010

The Role of Nonconserved Residues of Archaeoglobus fulgidus Ferritin on Its Unique Structure and Biophysical Properties

scientific article

The crystal structure of a cyanobacterial water-soluble carotenoid binding protein

scientific article

The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating

scientific article

The crystal structure of the Rv0301-Rv0300 VapBC-3 toxin-antitoxin complex fromM. tuberculosisreveals a Mg2+ion in the active site and a putative RNA-binding site

scientific article

The second Ca2+-binding domain of the Na+ Ca2+ exchanger is essential for regulation: crystal structures and mutational analysis

scientific article

The shape of the DNA minor groove directs binding by the DNA-bending protein Fis

scientific article

The structured core domain of B-crystallin can prevent amyloid fibrillation and associated toxicity

scientific article

Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis

scientific article (publication date: 23 May 2006)

Yeast Irc6p is a novel type of conserved clathrin coat accessory factor related to small G proteins ⬇️

scientific article published on September 19, 2012

List of works by Duilio Cascio

A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis

Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED.

An approach to crystallizing proteins by metal-mediated synthetic symmetrization

Atomic Structures Suggest Determinants of Transmission Barriers in Mammalian Prion Disease

Atomic View of a Toxic Amyloid Small Oligomer

Atomic structure of the cross-β spine of islet amyloid polypeptide (amylin)

Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity

Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.

Bacterial microcompartment shells of diverse functional types possess pentameric vertex proteins

Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3

Comparison of Two Yeast MnSODs: Mitochondrial Saccharomyces cerevisiae versus Cytosolic Candida albicans

Control of DNA minor groove width and Fis protein binding by the purine 2-amino group ⬇️

Crystal structure of a major secreted protein of Mycobacterium tuberculosis-MPT63 at 1.5-Å resolution

Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function

Crystallographic Studies of Prion Protein (PrP) Segments Suggest How Structural Changes Encoded by Polymorphism at Residue 129 Modulate Susceptibility to Human Prion Disease

De novo phasing with X-ray laser reveals mosquito larvicide BinAB structure

Discovery of a Thermophilic Protein Complex Stabilized by Topologically Interlinked Chains

Fis Targets Assembly of the Xis Nucleoprotein Filament to Promote Excisive Recombination by Phage Lambda

Granulysin crystal structure and a structure-derived lytic mechanism

Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions

Low-complexity domains adhere by reversible amyloid-like interactions between kinked β-sheets

MicroED Structures from Micrometer Thick Protein Crystals

Molecular basis for amyloid- polymorphism

Molecular mechanisms for protein-encoded inheritance

Regulation of clathrin adaptor function in endocytosis: novel role for the SAM domain

Site-directed spin labeling of a genetically encoded unnatural amino acid

Six-coordinate manganese(3+) in catalysis by yeast manganese superoxide dismutase ⬇️

Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65

Structural Insight into the Mechanisms of Transport across the Salmonella enterica Pdu Microcompartment Shell

Structural and EPR characterization of the soluble form of cytochrome c-550 and of the psbV2 gene product from the cyanobacterium Thermosynechococcus elongatus

Structural and Functional Studies of γ-Carboxyglutamic Acid Domains of Factor VIIa and Activated Protein C: Role of Magnesium at Physiological Calcium ⬇️

Structural determinants of nitroxide motion in spin-labeled proteins: Solvent-exposed sites in helix B of T4 lysozyme

Structural determinants of nitroxide motion in spin-labeled proteins: Tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme

Structural origin of weakly ordered nitroxide motion in spin-labeled proteins

Structure and Functional Studies of the CS Domain of the Essential H/ACA Ribonucleoparticle Assembly Protein SHQ1

Structure and Identification of a Pterin Dehydratase-like Protein as a Ribulose-bisphosphate Carboxylase/Oxygenase (RuBisCO) Assembly Factor in the α-Carboxysome

Structure and proposed activity of a member of the VapBC family of toxin-antitoxin systems. VapBC-5 from Mycobacterium tuberculosis

Structure of Dihydromethanopterin Reductase, a Cubic Protein Cage for Redox Transfer

Structure of a 16-nm cage designed by using protein oligomers

Structure of a Nudix protein from Pyrobaculum aerophilum reveals a dimer with two intersubunit beta-sheets

Structure of the cooperative Xis-DNA complex reveals a micronucleoprotein filament that regulates phage lambda intasome assembly

Structure of the dimerization domain of DiGeorge Critical Region 8

Structure of the toxic core of α-synuclein from invisible crystals

Structures and Functional Implications of an AMP-Binding Cystathionine β-Synthase Domain Protein from a Hyperthermophilic Archaeon

Structures of segments of α-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation

Synthetic symmetrization in the crystallization and structure determination of CelA fromThermotoga maritima

The 1.6 A resolution structure of Fe-superoxide dismutase from the thermophilic cyanobacterium Thermosynechococcus elongatus

The Crystal Structure of a Sodium Galactose Transporter Reveals Mechanistic Insights into Na+/Sugar Symport

The Role of Cys-298 in Aldose Reductase Function ⬇️

The Role of Nonconserved Residues of Archaeoglobus fulgidus Ferritin on Its Unique Structure and Biophysical Properties

The crystal structure of a cyanobacterial water-soluble carotenoid binding protein

The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating

The crystal structure of the Rv0301-Rv0300 VapBC-3 toxin-antitoxin complex fromM. tuberculosisreveals a Mg2+ion in the active site and a putative RNA-binding site

The second Ca2+-binding domain of the Na+ Ca2+ exchanger is essential for regulation: crystal structures and mutational analysis

The shape of the DNA minor groove directs binding by the DNA-bending protein Fis

The structured core domain of B-crystallin can prevent amyloid fibrillation and associated toxicity

Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis

Yeast Irc6p is a novel type of conserved clathrin coat accessory factor related to small G proteins ⬇️