List of works by Herman van Tilbeurgh

A Novel Protein-Protein Interaction in the RES (REtention and Splicing) Complex

scientific article (publication date: 10 October 2014)

A new alpha-helical extension promotes RNA binding by the dsRBD of Rnt1p RNAse III.

scientific article

Activation of the LicT transcriptional antiterminator involves a domain swing/lock mechanism provoking massive structural changes

scientific article published on 7 February 2005

Alpha repeat proteins (αRep) as expression and crystallization helpers

scientific article published on 16 August 2017

An archaeal orthologue of the universal protein Kae1 is an iron metalloprotein which exhibits atypical DNA-binding properties and apurinic-endonuclease activity in vitro

scientific article

Characterization of colicin M and its orthologs targeting bacterial cell wall peptidoglycan biosynthesis

scientific article published on 20 March 2012

Cloning, production, and purification of proteins for a medium-scale structural genomics project.

scientific article published in January 2007

Crystal structure and confirmation of the alanine:glyoxylate aminotransferase activity of the YFL030w yeast protein

scientific article

Crystal structure and functional characterization of yeast YLR011wp, an enzyme with NAD(P)H-FMN and ferric iron reductase activities

scientific article

Crystal structure of AFV1-102, a protein from theAcidianus Filamentous Virus 1

scientific article

Crystal structure of AFV3-109, a highly conserved protein from crenarchaeal viruses

scientific article

Crystal structure of YHI9, the yeast member of the phenazine biosynthesis PhzF enzyme superfamily

scientific article published in September 2005

Crystal structure of an intact type II DNA topoisomerase: insights into DNA transfer mechanisms

scientific article

Crystal structure of the YDR533c S. cerevisiae protein, a class II member of the Hsp31 family

scientific article published in May 2004

Crystal structure of the YGR205w protein from Saccharomyces cerevisiae: close structural resemblance to E. coli pantothenate kinase

scientific article

Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae

scientific article

Crystal structure of the effector AvrLm4-7 of Leptosphaeria maculans reveals insights into its translocation into plant cells and recognition by resistance proteins.

scientific article

Crystal structure of the yeast His6 enzyme suggests a reaction mechanism

scientific article

Crystal structure of the yeast Phox homology (PX) domain protein Grd19p complexed to phosphatidylinositol-3-phosphate

scientific article

Crystal structure of yeast FAD synthetase (Fad1) in complex with FAD

scientific article

Crystal structure of yeast allantoicase reveals a repeated jelly roll motif

scientific article

Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex

scientific article published on 3 March 2015

Crystallographic studies of the structured core domain of Knr4 from Saccharomyces cerevisiae

scientific article published on 25 August 2015

Data management in structural genomics: an overview

scientific article

Design of a data model for developing laboratory information management and analysis systems for protein production

scientific article

Design, production and molecular structure of a new family of artificial alpha-helicoidal repeat proteins (αRep) based on thermostable HEAT-like repeats

scientific article

Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways

scientific article

Evf, a virulence factor produced by the Drosophila pathogen Erwinia carotovora, is an S-palmitoylated protein with a new fold that binds to lipid vesicles

scientific article

Evolution of tRNAPhe:imG2 methyltransferases involved in the biosynthesis of wyosine derivatives in Archaea

scientific article published on 20 October 2016

Expression, purification and preliminary structural analysis of Escherichia coli MatP in complex with the matS DNA site

scientific article published on 22 May 2012

Found: the elusive ANTAR transcription antiterminator

scientific article

Functional and Structural Characterization of PaeM, a Colicin M-like Bacteriocin Produced by Pseudomonas aeruginosa

scientific article

HalX: an open-source LIMS (Laboratory Information Management System) for small- to large-scale laboratories

scientific article published on 26 May 2005

High-throughput crystal-optimization strategies in the South Paris Yeast Structural Genomics Project: one size fits all?

scientific article published on 26 May 2005

Hydrolysis of clavulanate by Mycobacterium tuberculosis β-lactamase BlaC harboring a canonical SDN motif

scientific article

Identification of a Mycoloyl Transferase Selectively Involved in O-Acylation of Polypeptides in Corynebacteriales

scientific article

In vitro biosynthesis of a universal t6A tRNA modification in Archaea and Eukarya

scientific article

Insights into molecular plasticity in protein complexes from Trm9-Trm112 tRNA modifying enzyme crystal structure

scientific article

Mechanism of activation of methyltransferases involved in translation by the Trm112 'hub' protein

scientific article published on 25 October 2015

Mechanistic and structural basis for inhibition of thymidylate synthase ThyX

scientific article

Modeling the ComD/ComE/comcde interaction network using small angle X-ray scattering

scientific article published on 11 March 2015

Molecular basis for bacterial class I release factor methylation by PrmC.

scientific article published in December 2005

ORF157 from the Archaeal Virus Acidianus Filamentous Virus 1 Defines a New Class of Nuclease

scientific article

Pichia pastoris is a valuable host for the expression of genes encoding membrane proteins from the hyperthermophilic Archeon Pyrococcus abyssi

scientific article published on 8 November 2006

Production and crystallization of protein domains: how useful are disorder predictions ?

scientific article published on April 2007

Prp43p contains a processive helicase structural architecture with a specific regulatory domain

scientific article

Selection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep)

scientific article

Specific GFP-binding artificial proteins (αRep): a new tool for in vitro to live cell applications

scientific article published on 12 June 2015

Structural and functional analysis of Nro1/Ett1: a protein involved in translation termination in S. cerevisiae and in O2-mediated gene control in S. pombe

scientific article

Structural and functional analysis of the fibronectin-binding protein FNE from Streptococcus equi spp. equi

scientific article

Structural and functional insights into Saccharomyces cerevisiae Tpa1, a putative prolylhydroxylase influencing translation termination and transcription

scientific article

Structural inhibition of the colicin D tRNase by the tRNA-mimicking immunity protein

scientific article

Structural insights into the dimerization of the response regulator ComE from Streptococcus pneumoniae

scientific article

Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity

scientific article

Structure of the archaeal Kae1/Bud32 fusion protein MJ1130: a model for the eukaryotic EKC/KEOPS subcomplex

scientific article

Structure of the yeast Pml1 splicing factor and its integration into the RES complex

scientific article

Structure of the yeast tRNA m7G methylation complex

scientific article

Structure of yeast Dom34: a protein related to translation termination factor Erf1 and involved in No-Go decay

scientific article

Structure-based functional annotation: yeast ymr099c codes for a D-hexose-6-phosphate mutarotase

scientific article

Structure-function analysis of Sua5 protein reveals novel functional motifs required for the biosynthesis of the universal t6A tRNA modification.

scientific article published on 12 April 2018

Structures of in vitro evolved binding sites on neocarzinostatin scaffold reveal unanticipated evolutionary pathways

scientific article published on 20 February 2006

Synthesis of avibactam derivatives and activity on β-lactamases and peptidoglycan biosynthesis enzymes of mycobacteria.

scientific article published on 30 March 2018

Systematic bioinformatics and experimental validation of yeast complexes reduces the rate of attrition during structural investigations.

scientific article published in September 2010

The ATP-mediated formation of the YgjD-YeaZ-YjeE complex is required for the biosynthesis of tRNA t6A in Escherichia coli

scientific article published on 10 January 2015

The Box H/ACA snoRNP Assembly Factor Shq1p is a Chaperone Protein Homologous to Hsp90 Cochaperones that Binds to the Cbf5p Enzyme

scientific article

The C-Terminal Domain from S. cerevisiae Pat1 Displays Two Conserved Regions Involved in Decapping Factor Recruitment

scientific article

The Carboxy-Terminal αN Helix of the Archaeal XerA Tyrosine Recombinase Is a Molecular Switch to Control Site-Specific Recombination

scientific article

The Family X DNA Polymerase from Deinococcus radiodurans Adopts a Non-standard Extended Conformation

scientific article

The H/ACA RNP assembly factor SHQ1 functions as an RNA mimic

scientific article

The crystal structure of ORF14 from Sulfolobus islandicus filamentous virus

scientific article

The crystal structure of Trz1, the long form RNase Z from yeast

scientific article published on 4 April 2017

The structure of FemX(Wv) in complex with a peptidyl-RNA conjugate: mechanism of aminoacyl transfer from Ala-tRNA(Ala) to peptidoglycan precursors

scientific article

The structure of an archaeal homodimeric ligase which has RNA circularization activity

scientific article

The structure of the NasR transcription antiterminator reveals a one-component system with a NIT nitrate receptor coupled to an ANTAR RNA-binding effector

scientific article

The structure of the TsaB/TsaD/TsaE complex reveals an unexpected mechanism for the bacterial t6A tRNA-modification.

scientific article published in June 2018

The thermo- and acido-stable ORF-99 from the archaeal virus AFV1

scientific article

The zinc finger protein Ynr046w is plurifunctional and a component of the eRF1 methyltransferase in yeast

scientific article

The αRep artificial repeat protein scaffold: a new tool for crystallization and live cell applications

scientific article

Tracing the origin of the fungal α1 domain places its ancestor in the HMG-box superfamily: implication for fungal mating-type evolution

scientific article

Trz1, the long form RNase Z from yeast, forms a stable heterohexamer with endonuclease Nuc1 and mutarotase

scientific article published on 12 September 2017

Two novel families of plasmids from hyperthermophilic archaea encoding new families of replication proteins

scientific article

X-Ray Structure and Site-Directed Mutagenesis Analysis of the Escherichia coli Colicin M Immunity Protein

scientific article

Zinc induces structural reorganization of gelatin binding domain from human fibronectin and affects collagen binding

scientific article