List of works by Kalle Gehring

1H, 13C and 15N resonance assignments of the bb' domains of human protein disulfide isomerase.

scientific article

1H, 13C and 15N resonance assignments of the catalytic domain of the goldfish RICH protein

article

1H, 13C and 15N resonance assignments of the human phosphatase PRL-3.

scientific article

1H, 13C, 15N NMR sequence-specific resonance assignment of a Clostridium thermocellum type II cohesin module

scientific article published on 01 May 2002

1H, 15N and 13C NMR assignments, secondary structure and overall topology of the Escherichia coli GlgS protein.

scientific article

1H, 15N and 13C resonance assignments and 15N-1H residual dipolar couplings for the alpha-adaptin ear-domain

scientific article published in July 2004

A PH-like domain of the Rab12 guanine nucleotide exchange factor DENND3 binds actin and is required for autophagy

scientific article published on 19 January 2018

A Ubl/ubiquitin switch in the activation of Parkin

scientific article

A novel RNA motif based on the structure of unusually stable 2',5'-linked r(UUCG) loops

scientific article

A structural overview of the PDI family of proteins

scientific article published on 26 August 2010

A tetrameric DNA structure with protonated cytosine.cytosine base pairs

scientific article

Acid multimers of oligodeoxycytidine strands: stoichiometry, base-pair characterization, and proton exchange properties

scientific article published on June 1993

Active transport of maltose in membrane vesicles obtained from Escherichia coli cells producing tethered maltose-binding protein

scientific article

Adult-onset painful axonal polyneuropathy caused by a dominant NAGLU mutation

scientific article

An NMR approach to structural proteomics

scientific article

An NMR study of ligand binding by maltodextrin binding protein

scientific article

An NMR study of ligand binding by maltodextrin binding protein

scientific article published in 1998

An RNA aptamer that selectively inhibits the enzymatic activity of protein tyrosine phosphatase 1B in vitro

scientific article published in July 2010

An interaction map of endoplasmic reticulum chaperones and foldases

scientific article

Ankyrin repeats as a dimerization module.

scientific article

Apoptotic Regulation by MCL-1 through Heterodimerization

scientific article

Applications procedures

Assignment of the 1H, 13C and 15N resonances of the catalytic domain of the rat 2',3'-cyclic nucleotide 3'-phosphodiesterase

scientific article published on 01 January 2002

Association of Branched Oligonucleotides into thei-Motif

Atypical binding of the Swa2p UBA domain to ubiquitin

scientific article

BID-induced structural changes in BAK promote apoptosis

scientific article

Bacteriophage lambda receptor site on the Escherichia coli K-12 LamB protein

scientific article

Bound Waters Mediate Binding of Diverse Substrates to a Ubiquitin Ligase

scientific article published on 27 March 2017

Calnexin cycle - structural features of the ER chaperone system

scientific article published on 13 April 2020

Characterization of a gamma-adaptin ear-binding motif in enthoprotin

scientific article

Characterization of polyacrylamide-stabilized Pfl phage liquid crystals for protein NMR spectroscopy

scientific article

Comparative peptide binding studies of the PABC domains from the ubiquitin-protein isopeptide ligase HYD and poly(A)-binding protein. Implications for HYD function

scientific journal article

Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains

scientific article

Conformational changes in the PBX homeodomain and C-terminal extension upon binding DNA and HOX-derived YPWM peptides

scientific article

Connecdenn, a novel DENN domain-containing protein of neuronal clathrin-coated vesicles functioning in synaptic vesicle endocytosis

scientific journal article

Contribution of structural genomics to understanding the biology of Escherichia coli

scientific article

Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements

scientific article published on 22 July 2019

Crystal Structure of the Salmonella Typhimurium Effector GtgE.

scientific article

Crystal structure of an archaeal CorB magnesium transporter

scientific article published on 29 June 2021

Crystal structure of the Legionella effector Lem22.

scientific article published on 21 November 2017

Crystal structure of the UBR-box from UBR6/FBXO11 reveals domain swapping mediated by zinc binding

scientific article published on 10 July 2017

Crystal structure of the bb' domains of the protein disulfide isomerase ERp57

scientific article

Deciphering the catalytic mechanism of bacterial ubiquitination

scientific article published in Nature

Design and solution structure of functional peptide mimetics of nerve growth factor

scientific article published on September 2000

Development of pharmacological agents for targeting neurotrophins and their receptors

scientific article

Disrupting the CD95–PLCγ1 interaction prevents Th17-driven inflammation

scientific article published on 14 November 2018

Divergent evolution of Di-lysine ER retention vs. farnesylation motif-mediated anchoring of the AnkB virulence effector to the Legionella-containing vacuolar membrane.

scientific article published on 11 July 2017

Diversity of ARSACS mutations in French-Canadians

scientific article

ERp57 and PDI: multifunctional protein disulfide isomerases with similar domain architectures but differing substrate-partner associations.

scientific article published on December 2006

ERp57 does not require interactions with calnexin and calreticulin to promote assembly of class I histocompatibility molecules, and it enhances peptide loading independently of its redox activity

scientific article published on 05 February 2009

Effect of peptide binding on amide proton exchange rates in the PDZ2 domain from human phosphatase hPTP1E

scientific article published on 01 January 1998

Effect of peptide binding on amide proton exchange rates in the PDZ2 domain from human phosphatase hPTP1E

scholarly article by Irena Ekiel published in January 1998

Erratum: PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3.

scientific article published on 21 July 2017

Existence and purification of porin heterotrimers of Escherichia coli K12 OmpC, OmpF, and PhoE proteins

scientific article

Genuine Monovalent Ligands of TrkA Nerve Growth Factor Receptors Reveal a Novel Pharmacological Mechanism of Action

scientific article published in Journal of Biological Chemistry

H(C)CH-COSY and (H)CCH-COSY experiments for 13C-labeled proteins in H2O solution

scientific article

Heat-Induced Dimerization of BCL-xLthrough α-Helix Swapping†

scientific article published in 2007

Heterodimerization of BAK and MCL-1 activated by detergent micelles

scientific article

High-Throughput Screening for Ligands of the HEPN Domain of Sacsin

scientific article

Influence of nucleotide modifications at the C2' position on the Hoogsteen base-paired parallel-stranded duplex of poly(A) RNA.

scientific article published in September 2017

Insights into function of PSI domains from structure of the Met receptor PSI domain

scientific article published in August 2004

Interaction between the human mitochondrial import receptors Tom20 and Tom70 in vitro suggests a chaperone displacement mechanism

scientific article published on 19 July 2011

Interdomain allostery promotes assembly of the poly(A) mRNA complex with PABP and eIF4G

scientific article

LARP1 and LARP4: up close with PABP for mRNA 3' poly(A) protection and stabilization

publication published on 31 January 2021

La-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA Stability

scientific article

Ligand Specificity in Fragment-Based Drug Design

scientific article published on 01 July 2010

Lock and key binding of the HOX YPWM peptide to the PBX homeodomain

scientific article

Maltose transport and starch binding in phage-resistant point mutants of maltoporin. Functional and topological implications

scientific article published on June 1988

Mapping the ER Interactome: The P Domains of Calnexin and Calreticulin as Plurivalent Adapters for Foldases and Chaperones

scientific article

Mechanism of parkin activation by phosphorylation

scientific article published on 02 July 2018

Mechanism of thienopyridone and iminothienopyridinedione inhibition of protein phosphatases

scientific article published on 05 April 2019

Mg2+-ATP Sensing in CNNM, a Putative Magnesium Transporter

scientific article published on 18 December 2019

Microcomputer interfaced stopped-flow spectrometer with interactive graphics

Mitochondrial dysfunction and Purkinje cell loss in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS)

scientific article published on 17 January 2012

Molecular basis of eRF3 recognition by the MLLE domain of poly(A)-binding protein

scientific article

Molecular determinants of PAM2 recognition by the MLLE domain of poly(A)-binding protein

scientific article

Molecular mechanisms in clathrin-mediated membrane budding revealed through subcellular proteomics

scientific article

NECAP 1 regulates AP-2 interactions to control vesicle size, number, and cargo during clathrin-mediated endocytosis

scientific article (publication date: October 2013)

NMR solution structure of an oligonucleotide hairpin with a 2'F-ANA/RNA stem: implications for RNase H specificity toward DNA/RNA hybrid duplexes

scientific article

NMR structural studies of human cystatin C dimers and monomers

NMR structural study of TcUBP1, a single RRM domain protein from Trypanosoma cruzi: contribution of a beta hairpin to RNA binding

scientific article

NMR structure of the enzyme GatB of the galactitol-specific phosphoenolpyruvate-dependent phosphotransferase system and its interaction with GatA

scientific article published on 8 September 2006

Nickel-induced oligomerization of proteins containing 10-histidine tags.

scientific article published in July 1998

PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3.

scientific article

PRL3 pseudophosphatase activity is necessary and sufficient to promote metastatic growth

scientific article published on 22 June 2020

Parkin structure and function

scientific article

Phosphatase, pseudo-phosphatase, or both? Understanding PRL oncogenicity

scientific article published on 03 December 2020

Phosphocysteine in the PRL-CNNM pathway mediates magnesium homeostasis

scientific article published on 17 November 2016

Phosphorylated ubiquitin: a new shade of PINK1 in Parkin activation

scientific article published on 20 June 2014

Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2

scientific article

Poly(A) nuclease interacts with the C-terminal domain of polyadenylate-binding protein domain from poly(A)-binding protein

scientific article

Poly(A)-binding protein-interacting protein 1 binds to eukaryotic translation initiation factor 3 to stimulate translation

scientific article published on 25 August 2008

Preparation and characterization of bacterial protein complexes for structural analysis

scientific article

Properties of arabinonucleic acids (ANA & 20'F-ANA): implications for the design of antisense therapeutics that invoke RNase H cleavage of RNA.

scientific article

Protein quality control in the ER: the recognition of misfolded proteins

scientific article published on 25 March 2010

Publisher Correction: Mechanism of parkin activation by phosphorylation

scientific article published on 01 August 2018

REDOR recoupling in polymer-stabilized liquid crystals undergoing MAS — Two-dimensional NMR applications with strongly aligned proteins

Rapid fold and structure determination of the archaeal translation elongation factor 1beta from Methanobacterium thermoautotrophicum

scientific article

Rational Design of Peptide Ligands Against a Glycolipid by NMR Studies

Reconstruction of diaminopimelic acid biosynthesis allows characterisation of Mycobacterium tuberculosis N-succinyl-L,L-diaminopimelic acid desuccinylase.

scientific article published on 15 March 2016

Recoupling of residual dipolar couplings in single-domain polymer-stabilized liquid crystals undergoing magic-angle spinning

scientific article published in October 2003

SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination

scientific article

Sacs knockout mice present pathophysiological defects underlying autosomal recessive spastic ataxia of Charlevoix-Saguenay

scientific article

Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria

scientific article published on 19 January 2022

Self-association studies of the bifunctional N-acetylglucosamine-1-phosphate uridyltransferase from Escherichia coli

scientific article published on 11 March 2011

Single-particle electron microscopy structure of UDP-glucose:glycoprotein glucosyltransferase suggests a selectivity mechanism for misfolded proteins

scientific article

Small-molecule ligands of GD2 ganglioside, designed from NMR studies, exhibit induced-fit binding and bioactivity

scientific article published in February 2010

Solution NMR Studies of a 42 KDaEscherichiaColiMaltose Binding Protein/β-Cyclodextrin Complex: Chemical Shift Assignments and Analysis

article

Solution Structure and Internal Motion of a Bioactive Peptide Derived from Nerve Growth Factor

scientific article published in Journal of Biological Chemistry

Solution structure of YaeO, a Rho-specific inhibitor of transcription termination

scientific article

Solution structure of a two-repeat fragment of major vault protein

scientific article

Solution structure of an arabinonucleic acid (ANA)/RNA duplex in a chimeric hairpin: comparison with 2'-fluoro-ANA/RNA and DNA/RNA hybrids

scientific article

Solution structure of human BCL-w: modulation of ligand binding by the C-terminal helix

scientific article (publication date: 6 June 2003)

Solution structure of the C-terminal domain from poly(A)-binding protein inTrypanosoma cruzi: A vegetal PABC domain

scientific article

Solution structure of the PABC domain from wheat poly (A)-binding protein: an insight into RNA metabolic and translational control in plants

scientific article

Solution structure of the PDZ2 domain from cytosolic human phosphatase hPTP1E complexed with a peptide reveals contribution of the beta2-beta3 loop to PDZ domain-ligand interactions

scientific article

Solution structure of the PDZ2 domain from human phosphatase hPTP1E and its interactions with C-terminal peptides from the Fas receptor

scientific article

Solution structure of the bb' domains of human protein disulfide isomerase

scientific article

Solution structure of the carbon storage regulator protein CsrA from Escherichia coli

scientific article

Solution structure of the catalytic domain of RICH protein from goldfish

scientific article

Solution structure of the orphan PABC domain from Saccharomyces cerevisiae poly(A)-binding protein

scientific article

Specific interaction of ERp57 and calnexin determined by NMR spectroscopy and an ER two-hybrid system

scientific article

Stability of Chimeric DNA/RNA Cytosine Tetrads: Implications fori-Motif Formation by RNA

scientific article published in 1998

Stimulation of glutamine transport by osmotic stress in Escherichia coli K-12.

scientific article

Stoichiometry of maltodextrin-binding sites in LamB, an outer membrane protein from Escherichia coli

scientific article

Structural Basis of Carbohydrate Recognition by Calreticulin

scientific article

Structural Basis of Cyclophilin B Binding by the Calnexin/Calreticulin P-domain

scientific article

Structural Basis of Defects in the Sacsin HEPN Domain Responsible for Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS)

scientific article

Structural Conservation in RNA Loops III and VI of the Internal Ribosome Entry Sites of Enteroviruses and Rhinoviruses

scientific article published in 1998

Structural Mimicry by a Bacterial F Box Effector Hijacks the Host Ubiquitin-Proteasome System

scientific article published on 10 January 2017

Structural and Functional Relationships between the Lectin and Arm Domains of Calreticulin

scientific article

Structural and Functional Study of Yer067w, a New Protein Involved in Yeast Metabolism Control and Drug Resistance

scientific article

Structural architecture of an outer membrane channel as determined by electron crystallography

scientific article published in March 1991

Structural basis for UBA-mediated dimerization of c-Cbl ubiquitin ligase

scientific article

Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b

scientific article

Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein

scientific article

Structural basis of ligand recognition by PABC, a highly specific peptide-binding domain found in poly(A)-binding protein and a HECT ubiquitin ligase

scientific article

Structural basis of substrate recognition and specificity in the N-end rule pathway

scientific article

Structural basis of ubiquitin recognition by the ubiquitin-associated (UBA) domain of the ubiquitin ligase EDD

scientific article

Structural characterization of three RNA hexanucleotide loops from the internal ribosome entry site of polioviruses

scientific article

Structural evidence that brain cyclic nucleotide phosphodiesterase is a member of the 2H phosphodiesterase superfamily

scientific article

Structural insight into the dimerization of human protein disulfide isomerase

scientific article

Structural insights into molecular function of the metastasis-associated phosphatase PRL-3

scientific article

Structural model of the BCL-w-BID peptide complex and its interactions with phospholipid micelles

scientific article

Structural proteomics of an archaeon

scientific article

Structural similarity of YbeD protein from Escherichia coli to allosteric regulatory domains

scientific article published on December 2004

Structural studies of parkin and sacsin: Mitochondrial dynamics in neurodegenerative diseases

scientific article published on 11 September 2015

Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family.

scientific article published on 20 September 2016

Structure and function of the C-terminal PABC domain of human poly(A)-binding protein

scientific article

Structure of 2′,5′-Linked Tetraribonucleotide Loops: A Novel RNA Motif

Structure of Escherichia coli tetrahydrodipicolinate N-succinyltransferase reveals the role of a conserved C-terminal helix in cooperative substrate binding

scientific article

Structure of GlgS from Escherichia coli suggests a role in protein-protein interactions

scientific article

Structure of Rpn10 and Its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12

scientific article

Structure of parkin reveals mechanisms for ubiquitin ligase activation

scientific article

Structure of the HECT C-lobe of the UBR5 E3 ubiquitin ligase

scientific article

Structure of the Legionella Effector, lpg1496, Suggests a Role in Nucleotide Metabolism.

scientific article

Structure of the Non-Catalytic Domain of the Protein Disulfide Isomerase-Related Protein (PDIR) Reveals Function in Protein Binding

scientific article

Structure of the archaeal translation initiation factor aIF2 from Methanobacterium thermoautotrophicum: Implications for translation initiation

scientific article

Structure of the catalytic a(0)a fragment of the protein disulfide isomerase ERp72

scientific article

Structure of the noncatalytic domains and global fold of the protein disulfide isomerase ERp72

scientific article

Structure of the parallel duplex of poly(A) RNA: evaluation of a 50 year-old prediction

scientific article

Structure of the substrate-binding b′ domain of the Protein disulfide isomerase-like protein of the testis

scientific article

Structure of the third catalytic domain of the protein disulfide isomerase ERp46

scientific article

Targeting of porin to the outer membrane of Escherichia coli. Rate of trimer assembly and identification of a dimer intermediate

scientific article

The "tale" of poly(A) binding protein: the MLLE domain and PAM2-containing proteins

scientific article published on 10 August 2014

The E3 ubiquitin ligase parkin is recruited to the 26 S proteasome via the proteasomal ubiquitin receptor Rpn13

scientific article

The MLLE domain of the ubiquitin ligase UBR5 binds to its catalytic domain to regulate substrate binding

scientific article

The NECAP PHear domain increases clathrin accessory protein binding potential

scientific article

The Solution Structure of YbcJ from Escherichia coli Reveals a Recently Discovered L Motif Involved in RNA Binding

scientific article

The X-ray structure of a BAK homodimer reveals an inhibitory zinc binding site

scientific article

The cyclic nucleotide–binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg2+ efflux activity

scientific article published in Journal of Biological Chemistry

The discovery of small molecule chemical probes of Bcl-X(L) and Mcl-1.

scientific article

The isolated La-module of LARP1 mediates 3' poly(A) protection and mRNA stabilization, dependent on its intrinsic PAM2 binding to PABPC1

scientific article published on 08 December 2020

The solution structure of ChaB, a putative membrane ion antiporter regulator from Escherichia coli

scientific article

The solution structure of the oxidative stress-related protein YggX from Escherichia coli

scientific article published on 9 May 2005

The structure of phosphate-bound Escherichia coli adenylosuccinate lyase identifies His171 as a catalytic acid

scientific article

Tn1000-mediated insertion mutagenesis of the histidine utilization (hut) gene cluster from Klebsiella aerogenes: genetic analysis of hut and unusual target specificity of Tn1000

scientific article published on October 1990

Triosephosphate isomerase is a common crystallization contaminant of soluble His-tagged proteins produced inEscherichia coli

scientific article

Tritium NMR spectroscopy of ligand binding to maltose-binding protein

scientific article

Two WXXF-based motifs in NECAPs define the specificity of accessory protein binding to AP-1 and AP-2.

scientific article published on 9 September 2004

Two modes of ligand binding in maltose-binding protein of Escherichia coli. Correlation with the structure of ligands and the structure of binding protein

scientific article published on July 1997

Two-Dimensional Nuclear Magnetic Resonance Method for Identifying the HN/N Signals of Amino-Acid Residues Following Glycine

scientific article published on 01 November 1995

UV difference spectroscopy of ligand binding to maltose-binding protein

scientific article

X-ray crystallography and NMR as tools for the study of protein tyrosine phosphatases

scientific article published on 27 July 2013

Zinc is required for structural stability of the C-terminus of archaeal translation initiation factor aIF2β

scientific article published on 01 April 2002