List of works - Mark Bartlam

A Novel and Fast Purification Method for Nucleoside Transporters ⬇️

scientific article published on 09 June 2016

A Versatile Strategy for Production of Membrane Proteins with Diverse Topologies: Application to Investigation of Bacterial Homologues of Human Divalent Metal Ion and Nucleoside Transporters ⬇️

scientific article published on 25 November 2015

A highly active single-mutation variant of P450BM3 (CYP102A1)

scientific article

Bioactive Terpenoids from Salvia plebeia: Structures, NO Inhibitory Activities, and Interactions with iNOS.

scientific article published on 14 November 2016

Bioactive ent-Pimarane and ent-Abietane Diterpenoids from the Whole Plants of Chloranthus henryi

scientific article published on 11 November 2015

Combination of biochar amendment and phytoremediation for hydrocarbon removal in petroleum-contaminated soil

scientific article published on 04 August 2016

Comparison of ITS and 18S rDNA for estimating fungal diversity using PCR-DGGE.

scientific article published on 17 June 2015

Complete Genome Sequence of Stenotrophomonas sp. Strain WZN-1, Which Is Capable of Degrading Polybrominated Diphenyl Ethers

scientific article

Correction: Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases

scientific article

Crystal Structure of the C-Terminal Cytoplasmic Domain of Non-Structural Protein 4 from Mouse Hepatitis Virus A59

scientific article

Crystal Structure of the Mp1p Ligand Binding Domain 2 Reveals Its Function as a Fatty Acid-binding Protein

scientific article

Crystal Structures of Two Coronavirus ADP-Ribose-1''-Monophosphatases and Their Complexes with ADP-Ribose: a Systematic Structural Analysis of the Viral ADRP Domain

scientific article

Crystal structure of ArgP from Mycobacterium tuberculosis confirms two distinct conformations of full-length LysR transcriptional regulators and reveals its function in DNA binding and transcriptional regulation

scientific article

Crystal structure of CYP199A2, a para-substituted benzoic acid oxidizing cytochrome P450 from Rhodopseudomonas palustris

scientific article

Crystal structure of RS21-C6, involved in nucleoside triphosphate pyrophosphohydrolysis

scientific article

Crystal structure of RecR, a member of the RecFOR DNA-repair pathway, from Pseudomonas aeruginosa PAO1

scientific article published on 22 March 2018

Crystal structure of a DNA binding protein from the hyperthermophilic euryarchaeonMethanococcus jannaschii

scientific article

Crystal structure of a carbonyl reductase fromCandida parapsilosiswith anti-Prelog stereospecificity

scientific article

Crystal structure of a ferredoxin reductase for the CYP199A2 system from Rhodopseudomonas palustris

scientific article

Crystal structure of a staphylokinase: variant a model for reduced antigenicity

scientific article

Crystal structure of alanine:glyoxylate aminotransferase and the relationship between genotype and enzymatic phenotype in primary hyperoxaluria type 1

scientific article

Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site

scientific article

Crystal structure of human E1 enzyme and its complex with a substrate analog reveals the mechanism of its phosphatase/enolase activity

scientific article

Crystal structure of human Gadd45 reveals an active dimer ⬇️

scientific article published on November 6, 2011

Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor

scientific article

Crystal structure of human pyrroline-5-carboxylate reductase

scientific article

Crystal structure of long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN: unveiling the long-chain alkane hydroxylase

scientific article

Crystal structure of mitochondrial respiratory membrane protein complex II

scientific article

Crystal structure of tabtoxin resistance protein complexed with acetyl coenzyme A reveals the mechanism for beta-lactam acetylation

scientific article

Crystal structure of the C-terminal domain of human DPY-30-like protein: A component of the histone methyltransferase complex

scientific article

Crystal structure of the N-terminal SH3 domain of mouse betaPIX, p21-activated kinase-interacting exchange factor

scientific article

Crystal structure of the catalytic domain of a human thioredoxin-like protein

scientific article

Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity

scientific article

Crystal structure of the hyperthermophilic inorganic pyrophosphatase from the archaeon Pyrococcus horikoshii

scientific article

Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus

scientific article

Crystal structure of the pyridoxal-5'-phosphate-dependent serine dehydratase from human liver

scientific article

Crystal structures of Nipah and Hendra virus fusion core proteins

scientific article

Crystal structures of human BTG2 and mouse TIS21 involved in suppression of CAF1 deadenylase activity

scientific article

Crystal structures of human glycerol 3-phosphate dehydrogenase 1 (GPD1)

scientific article

Crystal-structure and biochemical characterization of recombinant human calcyphosine delineates a novel EF-hand-containing protein family

scientific article

Crystallization and preliminary crystallographic analysis of a metastasis-inducing protein, human S100A4

scientific article (publication date: 2002)

Crystallization and preliminary crystallographic analysis of transgelin

scientific article

Design and Structure-Based Study of New Potential FKBP12 Inhibitors ⬇️

scientific article published on November 1, 2003

Design of wide-spectrum inhibitors targeting coronavirus main proteases

scientific article

Distribution and diversity of fungi in freshwater sediments on a river catchment scale.

scientific article published on 21 April 2015

Functional Characterization of the γ-Aminobutyric Acid Transporter from <i>Mycobacterium smegmatis</i> MC<sup>2</sup> 155 Reveals Sodium-Driven GABA Transport

scientific article published on 07 December 2020

Genome Sequence of a Typical Ultramicrobacterium, Curvibacter sp. Strain PAE-UM, Capable of Phthalate Ester Degradation

scientific article

Insights into the structure and architecture of the CCR4-NOT complex

scientific article

Isolation, Characterization, and Antiproliferative Activities of Eudesmanolide Derivatives from the Flowers of Inula japonica

scientific article published on October 2015

Mechanism of Dephosphorylation of Glucosyl-3-phosphoglycerate by a Histidine Phosphatase

scientific article

Molecular Characterization of a Class I P450 Electron Transfer System from Novosphingobium aromaticivorans DSM12444

scientific article

Nucleoside Monophosphate Complex Structures of the Endonuclease Domain from the Influenza Virus Polymerase PA Subunit Reveal the Substrate Binding Site inside the Catalytic Center

scientific article

PDlim2 Selectively Interacts with the PDZ Binding Motif of Highly Pathogenic Avian H5N1 Influenza A Virus NS1 ⬇️

scientific article published on May 23, 2011

Production of authentic SARS-CoV M(pro) with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction

scientific article

Protein recognition in ferredoxin-P450 electron transfer in the class I CYP199A2 system from Rhodopseudomonas palustris

scientific article

Purification, crystallization and X-ray crystallographic analysis of a putative exopolyphosphatase from Zymomonas mobilis.

scientific article

Sesquiterpenes from Carpesium macrocephalum inhibit Candida albicans biofilm formation and dimorphism

article

Spatial-Temporal Changes of Bacterioplankton Community along an Exhorheic River

scientific article published on 3 March 2016

Spatio-Temporal Variations of High and Low Nucleic Acid Content Bacteria in an Exorheic River

scientific article

Structural Analysis of CYP101C1 from Novosphingobium aromaticivorans DSM12444

scientific article

Structural analysis of Mycobacterium tuberculosis ATP-binding cassette transporter subunit UgpB reveals specificity for glycerophosphocholine

scientific article

Structural and Biochemical Analysis of Tyrosine Phosphatase Related to Biofilm Formation A (TpbA) from the Opportunistic Pathogen Pseudomonas aeruginosa PAO1

scientific article

Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis

scientific article

Structural basis for a reciprocating mechanism of negative cooperativity in dimeric phosphagen kinase activity

scientific article

Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach

scientific article published on 30 October 2015

Structural basis for inhibition of the deadenylase activity of human CNOT6L

scientific article

Structural basis for prokaryotic calciummediated regulation by a Streptomyces coelicolor calcium binding protein

scientific article

Structural basis for proteolytic specificity of the human apoptosis-inducing granzyme M

scientific article

Structural basis for the properties of two single-site proline mutants of CYP102A1 (P450BM3)

scientific article

Structural basis for the recognition of MucA by MucB and AlgU in Pseudomonas aeruginosa

scientific article published on 11 July 2019

Structural basis for the specific recognition of RET by the Dok1 phosphotyrosine binding domain

scientific article

Structural basis of Robo proline-rich motif recognition by the srGAP1 Src homology 3 domain in the Slit-Robo signaling pathway

scientific article

Structural implications of a G170R mutation of alanine:glyoxylate aminotransferase that is associated with peroxisome-to-mitochondrion mistargeting

scientific article

Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1.

scientific article published on 23 November 2015

Structural insights into diversity and n-alkane biodegradation mechanisms of alkane hydroxylases

scientific article published on 21 March 2013

Structural proteomics of the SARS coronavirus: a model response to emerging infectious diseases

scientific article

Structure and characterization of a NAD(P)H-dependent carbonyl reductase from Pseudomonas aeruginosa PAO1.

scientific article published on 19 May 2017

Structure and cleavage specificity of the chymotrypsin-like serine protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)

scientific article

Structure and function of CYP108D1 from Novosphingobium aromaticivorans DSM12444: an aromatic hydrocarbon-binding P450 enzyme

scientific article

Structure of human cytosolic X-prolyl aminopeptidase: a double Mn(II)-dependent dimeric enzyme with a novel three-domain subunit

scientific article

Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione

scientific article

Structure of the Main Protease from a Global Infectious Human Coronavirus, HCoV-HKU1

scientific article

Structure, electronic properties and catalytic behaviour of an activity-enhancing CYP102A1 (P450(BM3)) variant

scientific article

Structure-Functional Analyses of CRHSP-24 Plasticity and Dynamics in Oxidative Stress Response ⬇️

scientific article published on December 22, 2010

Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China ⬇️

scientific article published on June 4, 2010

Structures of Two Coronavirus Main Proteases: Implications for Substrate Binding and Antiviral Drug Design

scientific article

Substrate binding and catalysis in trichosanthin occur in different sites as revealed by the complex structures of several E85 mutants

scientific article

The Crystal Structure of Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein Nsp1 Reveals a Novel Metal-Dependent Nuclease

scientific article

The crystal structure of MCAT from Mycobacterium tuberculosis reveals three new catalytic models

scientific article

The crystal structure of human isopentenyl diphosphate isomerase at 1.7 A resolution reveals its catalytic mechanism in isoprenoid biosynthesis

scientific article

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor ⬇️

scientific article published on October 29, 2003

The structure of CYP101D2 unveils a potential path for substrate entry into the active site

scientific article

Transport mechanism of a glutamate transporter homologue GltPh ⬇️

scientific article

List of works by Mark Bartlam

A Novel and Fast Purification Method for Nucleoside Transporters ⬇️

A Versatile Strategy for Production of Membrane Proteins with Diverse Topologies: Application to Investigation of Bacterial Homologues of Human Divalent Metal Ion and Nucleoside Transporters ⬇️

A highly active single-mutation variant of P450BM3 (CYP102A1)

Bioactive Terpenoids from Salvia plebeia: Structures, NO Inhibitory Activities, and Interactions with iNOS.

Bioactive ent-Pimarane and ent-Abietane Diterpenoids from the Whole Plants of Chloranthus henryi

Combination of biochar amendment and phytoremediation for hydrocarbon removal in petroleum-contaminated soil

Comparison of ITS and 18S rDNA for estimating fungal diversity using PCR-DGGE.

Complete Genome Sequence of Stenotrophomonas sp. Strain WZN-1, Which Is Capable of Degrading Polybrominated Diphenyl Ethers

Correction: Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases

Crystal Structure of the C-Terminal Cytoplasmic Domain of Non-Structural Protein 4 from Mouse Hepatitis Virus A59

Crystal Structure of the Mp1p Ligand Binding Domain 2 Reveals Its Function as a Fatty Acid-binding Protein

Crystal Structures of Two Coronavirus ADP-Ribose-1''-Monophosphatases and Their Complexes with ADP-Ribose: a Systematic Structural Analysis of the Viral ADRP Domain

Crystal structure of ArgP from Mycobacterium tuberculosis confirms two distinct conformations of full-length LysR transcriptional regulators and reveals its function in DNA binding and transcriptional regulation

Crystal structure of CYP199A2, a para-substituted benzoic acid oxidizing cytochrome P450 from Rhodopseudomonas palustris

Crystal structure of RS21-C6, involved in nucleoside triphosphate pyrophosphohydrolysis

Crystal structure of RecR, a member of the RecFOR DNA-repair pathway, from Pseudomonas aeruginosa PAO1

Crystal structure of a DNA binding protein from the hyperthermophilic euryarchaeonMethanococcus jannaschii

Crystal structure of a carbonyl reductase fromCandida parapsilosiswith anti-Prelog stereospecificity

Crystal structure of a ferredoxin reductase for the CYP199A2 system from Rhodopseudomonas palustris

Crystal structure of a staphylokinase: variant a model for reduced antigenicity

Crystal structure of alanine:glyoxylate aminotransferase and the relationship between genotype and enzymatic phenotype in primary hyperoxaluria type 1

Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site

Crystal structure of human E1 enzyme and its complex with a substrate analog reveals the mechanism of its phosphatase/enolase activity

Crystal structure of human Gadd45 reveals an active dimer ⬇️

Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor

Crystal structure of human pyrroline-5-carboxylate reductase

Crystal structure of long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN: unveiling the long-chain alkane hydroxylase

Crystal structure of mitochondrial respiratory membrane protein complex II

Crystal structure of tabtoxin resistance protein complexed with acetyl coenzyme A reveals the mechanism for beta-lactam acetylation

Crystal structure of the C-terminal domain of human DPY-30-like protein: A component of the histone methyltransferase complex

Crystal structure of the N-terminal SH3 domain of mouse betaPIX, p21-activated kinase-interacting exchange factor

Crystal structure of the catalytic domain of a human thioredoxin-like protein

Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity

Crystal structure of the hyperthermophilic inorganic pyrophosphatase from the archaeon Pyrococcus horikoshii

Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus

Crystal structure of the pyridoxal-5'-phosphate-dependent serine dehydratase from human liver

Crystal structures of Nipah and Hendra virus fusion core proteins

Crystal structures of human BTG2 and mouse TIS21 involved in suppression of CAF1 deadenylase activity

Crystal structures of human glycerol 3-phosphate dehydrogenase 1 (GPD1)

Crystal-structure and biochemical characterization of recombinant human calcyphosine delineates a novel EF-hand-containing protein family

Crystallization and preliminary crystallographic analysis of a metastasis-inducing protein, human S100A4

Crystallization and preliminary crystallographic analysis of transgelin

Design and Structure-Based Study of New Potential FKBP12 Inhibitors ⬇️

Design of wide-spectrum inhibitors targeting coronavirus main proteases

Distribution and diversity of fungi in freshwater sediments on a river catchment scale.

Functional Characterization of the γ-Aminobutyric Acid Transporter from <i>Mycobacterium smegmatis</i> MC<sup>2</sup> 155 Reveals Sodium-Driven GABA Transport

Genome Sequence of a Typical Ultramicrobacterium, Curvibacter sp. Strain PAE-UM, Capable of Phthalate Ester Degradation

Insights into the structure and architecture of the CCR4-NOT complex

Isolation, Characterization, and Antiproliferative Activities of Eudesmanolide Derivatives from the Flowers of Inula japonica

Mechanism of Dephosphorylation of Glucosyl-3-phosphoglycerate by a Histidine Phosphatase

Molecular Characterization of a Class I P450 Electron Transfer System from Novosphingobium aromaticivorans DSM12444

Nucleoside Monophosphate Complex Structures of the Endonuclease Domain from the Influenza Virus Polymerase PA Subunit Reveal the Substrate Binding Site inside the Catalytic Center

PDlim2 Selectively Interacts with the PDZ Binding Motif of Highly Pathogenic Avian H5N1 Influenza A Virus NS1 ⬇️

Production of authentic SARS-CoV M(pro) with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction

Protein recognition in ferredoxin-P450 electron transfer in the class I CYP199A2 system from Rhodopseudomonas palustris

Purification, crystallization and X-ray crystallographic analysis of a putative exopolyphosphatase from Zymomonas mobilis.

Sesquiterpenes from Carpesium macrocephalum inhibit Candida albicans biofilm formation and dimorphism

Spatial-Temporal Changes of Bacterioplankton Community along an Exhorheic River

Spatio-Temporal Variations of High and Low Nucleic Acid Content Bacteria in an Exorheic River

Structural Analysis of CYP101C1 from Novosphingobium aromaticivorans DSM12444

Structural analysis of Mycobacterium tuberculosis ATP-binding cassette transporter subunit UgpB reveals specificity for glycerophosphocholine

Structural and Biochemical Analysis of Tyrosine Phosphatase Related to Biofilm Formation A (TpbA) from the Opportunistic Pathogen Pseudomonas aeruginosa PAO1

Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis

Structural basis for a reciprocating mechanism of negative cooperativity in dimeric phosphagen kinase activity

Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach

Structural basis for inhibition of the deadenylase activity of human CNOT6L

Structural basis for prokaryotic calciummediated regulation by a Streptomyces coelicolor calcium binding protein

Structural basis for proteolytic specificity of the human apoptosis-inducing granzyme M

Structural basis for the properties of two single-site proline mutants of CYP102A1 (P450BM3)

Structural basis for the recognition of MucA by MucB and AlgU in Pseudomonas aeruginosa

Structural basis for the specific recognition of RET by the Dok1 phosphotyrosine binding domain

Structural basis of Robo proline-rich motif recognition by the srGAP1 Src homology 3 domain in the Slit-Robo signaling pathway

Structural implications of a G170R mutation of alanine:glyoxylate aminotransferase that is associated with peroxisome-to-mitochondrion mistargeting

Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1.

Structural insights into diversity and n-alkane biodegradation mechanisms of alkane hydroxylases

Structural proteomics of the SARS coronavirus: a model response to emerging infectious diseases

Structure and characterization of a NAD(P)H-dependent carbonyl reductase from Pseudomonas aeruginosa PAO1.

Structure and cleavage specificity of the chymotrypsin-like serine protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)

Structure and function of CYP108D1 from Novosphingobium aromaticivorans DSM12444: an aromatic hydrocarbon-binding P450 enzyme