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List of works by Mavis Agbandje-McKenna

A Rationally Engineered Capsid Variant of AAV9 for Systemic CNS-Directed and Peripheral Tissue-Detargeted Gene Delivery in Neonates.

scientific article

A Short, Strong Hydrogen Bond in the Active Site of Human Carbonic Anhydrase II

scientific article

A dual role of EGFR protein tyrosine kinase signaling in ubiquitination of AAV2 capsids and viral second-strand DNA synthesis

scientific article published on 17 April 2007

A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection

scientific article

A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency.

scientific article published in July 2018

A simplified purification protocol for recombinant adeno-associated virus vectors.

scientific article published on 13 August 2014

AAV capsid structure and cell interactions

scientific article

AAV6 K531 serves a dual function in selective receptor and antibody ADK6 recognition.

scientific article published on 28 March 2018

Actin crystal dynamics: structural implications for F-actin nucleation, polymerization, and branching mediated by the anti-parallel dimer

scientific article published in June 2004

Active-site specificity of digestive aspartic peptidases from the four species of Plasmodium that infect humans using chromogenic combinatorial peptide libraries

scientific article published in February 2005

Adeno-Associated Virus (AAV) Capsid Stability and Liposome Remodeling During Endo/Lysosomal pH Trafficking

scientific article published on 20 June 2020

Adeno-Associated Virus VP1u Exhibits Protease Activity.

scientific article

Adeno-associated Virus 9 Structural Rearrangements Induced by Endosomal Trafficking pH and Glycan Attachment

scientific article published on 14 July 2021

Adeno-associated virus capsid proteins may play a role in transcription and second-strand synthesis of recombinant genomes

scientific article published on 6 November 2013

Adeno-associated virus capsid serotype identification: Analytical methods development and application

scientific article

Adeno-associated virus capsid structure drives CD4-dependent CD8+ T cell response to vector encoded proteins

scientific article published in May 2009

Adeno-associated virus serotype 1 (AAV1)- and AAV5-antibody complex structures reveal evolutionary commonalities in parvovirus antigenic reactivity

scientific article published on 19 November 2014

Adeno-associated virus structural biology as a tool in vector development ⬇️

scientific article published on December 2013

Adeno-associated virus type 2 contains an integrin alpha5beta1 binding domain essential for viral cell entry

scientific article published on September 2006

Alpha2,3 and alpha2,6 N-linked sialic acids facilitate efficient binding and transduction by adeno-associated virus types 1 and 6

scientific article

An Ancient Lineage of Highly Divergent Parvoviruses Infects both Vertebrate and Invertebrate Hosts

scientific article published on 06 June 2019

An extension of the Minute Virus of Mice tissue tropism

scientific article

Analysis of HIV-1 CRF_01 A/E protease inhibitor resistance: structural determinants for maintaining sensitivity and developing resistance to atazanavir

scientific article published on May 2006

Analysis of binding interactions of pepsin inhibitor-3 to mammalian and malarial aspartic proteases

scientific article published on 16 November 2007

Apo-Human Carbonic Anhydrase II Revisited: Implications of the Loss of a Metal in Protein Structure, Stability, and Solvent Network ,

scientific article

Assembly and disassembly intermediates of maize streak geminivirus

scientific article published on 06 October 2018

Assembly and structural analysis of a covalently closed nano-scale DNA cage.

scientific article

Atomic Resolution Structure of the Oncolytic Parvovirus LuIII by Electron Microscopy and 3D Image Reconstruction

scientific article

Atomic Resolution Structures of Human Bufaviruses Determined by Cryo-Electron Microscopy

scientific article published on 4 January 2018

Atomic crystal and molecular dynamics simulation structures of human carbonic anhydrase II: insights into the proton transfer mechanism

scientific article

Atomic structure of a rationally engineered gene delivery vector, AAV2.5.

scientific article

Attenuation of Heparan Sulfate Proteoglycan Binding Enhances In Vivo Transduction of Human Primary Hepatocytes with AAV2

scientific article published on 13 May 2020

BAAV transcytosis requires an interaction with beta-1-4 linked- glucosamine and gp96

scientific article (publication date: 9 March 2010)

Capsid antibodies to different adeno-associated virus serotypes bind common regions.

scientific article published on 12 June 2013

Characterization of AAV-Specific Affinity Ligands: Consequences for Vector Purification and Development Strategies

scientific article published on 04 October 2020

Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds

scientific article published in October 2011

Characterization of naturally-occurring humoral immunity to AAV in sheep

scientific article

Characterization of the Adeno-Associated Virus 1 and 6 Sialic Acid Binding Site

scientific article published on 09 March 2016

Cloning, expression, purification, crystallization and preliminary X-ray analysis of Mycoplasma genitalium protein MG289.

scientific article published on 22 August 2009

Co-evolution of AAV capsid antigenicity and tropism through a structure-guided approach

scientific article published on 15 July 2020

Combinations of two capsid regions controlling canine host range determine canine transferrin receptor binding by canine and feline parvoviruses

scientific article

Comparative Analysis of the Capsid Structures of AAVrh.10, AAVrh.39, and AAV8

scientific article published on 28 February 2020

Comparative analysis of adeno-associated virus capsid stability and dynamics

scientific article

Comparing the accumulation of active- and nonactive-site mutations in the HIV-1 protease

scientific article published in September 2004

Construction, expression, and purification of recombinant αVβ5 integrin ⬇️

scientific article published on April 12, 2013

Correction: Targeting Photoreceptors via Intravitreal Delivery Using Novel, Capsid-Mutated AAV Vectors.

scientific article published on 20 September 2013

Creating an arsenal of Adeno-associated virus (AAV) gene delivery stealth vehicles.

scientific article published on 3 May 2018

Cryo-electron Microscopy Reconstruction and Stability Studies of the Wild Type and the R432A Variant of Adeno-associated Virus Type 2 Reveal that Capsid Structural Stability Is a Major Factor in Genome Packaging

scientific article published on 20 July 2016

Cryoannealing-induced space-group transition of crystals of the carbonic anhydrase psCA3.

scientific article published on 28 June 2016

Crystallization and preliminary X-ray analysis of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae

scientific article

Crystallization and preliminary X-ray analysis of the tumor metastasis factor p37.

scientific article published on 23 November 2002

Crystallization and preliminary X-ray crystallographic studies on recombinant human carnitine acetyltransferase

scientific article

Crystallization and preliminary X-ray crystallographic studies on recombinant rat choline acetyltransferase

scientific article published on 23 January 2004

Crystallographic evidence for noncoplanar catalytic aspartic acids in plasmepsin II resides in the Protein Data Bank

scientific article

Current opinion in virology: structural virology ⬇️

scientific article published on July 19, 2011

Defining the stoichiometry and cargo load of viral and bacterial nanoparticles by Orbitrap mass spectrometry

scientific article published on 7 May 2014

Design of a Carbonic Anhydrase IX Active-Site Mimic To Screen Inhibitors for Possible Anticancer Properties † ‡

scientific article

Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation

scientific article

Development of Patient-specific AAV Vectors After Neutralizing Antibody Selection for Enhanced Muscle Gene Transfer

scientific article

Direct Head-to-Head Evaluation of Recombinant Adeno-associated Viral Vectors Manufactured in Human versus Insect Cells

scientific article published on 10 August 2017

Diversity of environmental single-stranded DNA phages revealed by PCR amplification of the partial major capsid protein

scientific article

Emerging from pseudo-symmetry: the redetermination of human carbonic anhydrase II in monoclinicP21with a doubledaaxis ⬇️

scientific article published on July 9, 2010

Endogenous amdoparvovirus-related elements reveal insights into the biology and evolution of vertebrate parvoviruses

Engineering Liver-detargeted AAV9 Vectors for Cardiac and Musculoskeletal Gene Transfer ⬇️

scientific article published on March 1, 2011

Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles

Engineering and selection of shuffled AAV genomes: a new strategy for producing targeted biological nanoparticles

scientific article

Engraftment of a Galactose Receptor Footprint onto Adeno-associated Viral Capsids Improves Transduction Efficiency ⬇️

scientific article published on August 12, 2013

Enhanced Transduction of Human Hematopoietic Stem Cells by AAV6 Vectors: Implications in Gene Therapy and Genome Editing

scientific article published on 29 March 2020

Entrapment of Carbon Dioxide in the Active Site of Carbonic Anhydrase II

scientific article

Evidence for pH-Dependent Protease Activity in the Adeno-Associated Virus Capsid ⬇️

scientific article published on August 22, 2012

Examining the cross-reactivity and neutralization mechanisms of a panel of mAbs against adeno-associated virus serotypes 1 and 5 ⬇️

scientific article published on November 9, 2011

Functional glycomic analysis of human milk glycans reveals the presence of virus receptors and embryonic stem cell biomarkers

scientific article

Gene transfer properties and structural modeling of human stem cell-derived AAV.

scientific article published on 13 June 2014

Generation and characterization of anti-Adeno-associated virus serotype 8 (AAV8) and anti-AAV9 monoclonal antibodies

scientific article published on 13 July 2016

Generation of novel AAV variants by directed evolution for improved CFTR delivery to human ciliated airway epithelium

scientific article published on 14 July 2009

Germline viral "fossils" guide in silico reconstruction of a mid-Cenozoic era marsupial adeno-associated virus

scientific article

Heparin binding induces conformational changes in Adeno-associated virus serotype 2.

scientific article published on 13 December 2008

High resolution structural characterization of a new AAV5 antibody epitope toward engineering antibody resistant recombinant gene delivery vectors

article

High-efficiency transduction of human monocyte-derived dendritic cells by capsid-modified recombinant AAV2 vectors.

scientific article

High-resolution structure of human carbonic anhydrase II complexed with acetazolamide reveals insights into inhibitor drug design

scientific article

Host-selected amino acid changes at the sialic acid binding pocket of the parvovirus capsid modulate cell binding affinity and determine virulence

scientific article

Human bocavirus capsid structure: insights into the structural repertoire of the parvoviridae

scientific article

Human carbonic anhydrase III: structural and kinetic study of catalysis and proton transfer

scientific article published in August 2005

Human hepatocyte growth factor receptor is a cellular coreceptor for adeno-associated virus serotype 3

scientific article

ICTV Virus Taxonomy Profile: Parvoviridae

scientific article published on 23 January 2019

Identification and mutagenesis of the adeno-associated virus 5 sialic acid binding region

scientific article

Identification of amino acid residues in the capsid proteins of adeno-associated virus type 2 that contribute to heparan sulfate proteoglycan binding

scientific article

Identification of the galactose binding domain of the adeno-associated virus serotype 9 capsid

scientific article

Identification of the sialic acid structures recognized by minute virus of mice and the role of binding affinity in virulence adaptation

scientific article published on 5 July 2006

Impact of Heparan Sulfate Binding on Transduction of Retina by Recombinant Adeno-Associated Virus Vectors

scientific article published on 10 February 2016

Impact of natural or synthetic singletons in the capsid of human bocavirus 1 on particle infectivity and immunoreactivity

scientific article published on 25 March 2020

Inhibition of carbonic anhydrase II by thioxolone: a mechanistic and structural study

scientific article

Insights into Mycoplasma genitalium metabolism revealed by the structure of MG289, an extracytoplasmic thiamine binding lipoprotein ⬇️

scientific article published on February 1, 2011

Isolation and characterization of subgenomic DNAs encapsidated in "single" T = 1 isometric particles of Maize streak virus

scientific article published in May 2004

Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II ⬇️

scientific article published on June 12, 2012

Little vector, big gene transduction: fragmented genome reassembly of adeno-associated virus

scientific article published on January 2010

Mapping Antigenic Epitopes on the Human Bocavirus Capsid

scientific article published on 24 February 2016

Mapping a Neutralizing Epitope onto the Capsid of Adeno-Associated Virus Serotype 8 ⬇️

scientific article published on May 16, 2012

Mapping the AAV Capsid Host Antibody Response toward the Development of Second Generation Gene Delivery Vectors

scientific article published on 30 January 2014

Mapping the structural determinants responsible for enhanced T cell activation to the immunogenic adeno-associated virus capsid from isolate rhesus 32.33.

scientific article published on 29 May 2013

Microviridae, a family divided: isolation, characterization, and genome sequence of phiMH2K, a bacteriophage of the obligate intracellular parasitic bacterium Bdellovibrio bacteriovorus

scientific article

Mining the protein data bank to differentiate error from structural variation in clustered static structures: an examination of HIV protease

scientific article

Modeling virus self-assembly pathways: avoiding dynamics using geometric constraint decomposition

scientific article published in July 2006

Molecular biology and structure of a novel penaeid shrimp densovirus elucidate convergent parvoviral host capsid evolution

scientific article published on 03 August 2020

Molecular characterization of the heparin-dependent transduction domain on the capsid of a novel adeno-associated virus isolate, AAV(VR-942)

scientific article published on 4 June 2008

Molecular cloning, overexpression, and an efficient one-step purification of α5β1 integrin

scientific article published on 29 August 2013

Mutants at the 2-Fold Interface of Adeno-associated Virus Type 2 (AAV2) Structural Proteins Suggest a Role in Viral Transcription for AAV Capsids

scientific article published on June 2016

Neurovirulence of polytropic murine retrovirus is influenced by two separate regions on opposite sides of the envelope protein receptor binding domain

scientific article published on 25 June 2008

Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses

scholarly article

Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina

scientific article

OneBac 2.0: Sf9 Cell Lines for Production of AAV1, AAV2, and AAV8 Vectors with Minimal Encapsidation of Foreign DNA.

scientific article published on 26 January 2017

OneBac: platform for scalable and high-titer production of adeno-associated virus serotype 1-12 vectors for gene therapy

scientific article published on 23 January 2014

Optimization of the capsid of recombinant adeno-associated virus 2 (AAV2) vectors: the final threshold?

scientific article

Optimizing the Targeting of Mouse Parvovirus 1 to Murine Melanoma Selects for Recombinant Genomes and Novel Mutations in the Viral Capsid Gene

scientific article published on 30 January 2018

Parvovirus Capsid Structures Required for Infection: Mutations Controlling Receptor Recognition and Protease Cleavages.

scientific article published on 9 November 2016

Parvovirus Capsid-Antibody Complex Structures Reveal Conservation of Antigenic Epitopes Across the Family

scientific article published on 21 April 2020

Parvovirus Family Conundrum: What Makes a Killer?

scientific article

Parvovirus glycan interactions

scientific article

Parvoviruses: structure and infection

article

Phase 1 Gene Therapy for Duchenne Muscular Dystrophy Using a Translational Optimized AAV Vector ⬇️

scientific article published on November 8, 2011

Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution

scientific article

Pre-arrayed Pan-AAV Peptide Display Libraries for Rapid Single-Round Screening

scientific article published on 13 February 2020

Prevalence of AAV3 capsid binding and neutralizing antibodies in healthy and individuals with hemophilia B from India

scientific article published on 18 November 2020

Production and X-ray crystallographic analysis of fully deuterated human carbonic anhydrase II.

scientific article

Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 1.

scientific article published on 30 November 2006

Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 4.

scientific article published in February 2003

Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 7.

scientific article published on 30 November 2007

Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 9

scientific article published on 27 June 2009

Production, purification, crystallization and preliminary X-ray analysis of adeno-associated virus serotype 8.

scientific article

Production, purification, crystallization and preliminary X-ray structural studies of adeno-associated virus serotype 5

scientific article

Production, purification, crystallization and structure determination ofH-1 Parvovirus ⬇️

scientific article published on November 28, 2012

Profiling of glycan receptors for minute virus of mice in permissive cell lines towards understanding the mechanism of cell recognition

scientific article published on 27 January 2014

Protease-Activatable Adeno-Associated Virus Vector for Gene Delivery to Damaged Heart Tissue

scientific article published on 29 January 2019

Proteolytic mapping of the adeno-associated virus capsid

scientific article published on 27 September 2006

Random Insertion of mCherry Into VP3 Domain of Adeno-associated Virus Yields Fluorescent Capsids With no Loss of Infectivity ⬇️

scientific article published on November 13, 2012

Rationally Engineered AAV Capsids Improve Transduction and Volumetric Spread in the CNS

scientific article published on 21 June 2017

Receptor Switching in Newly Evolved Adeno-associated Viruses

scientific article published on 09 September 2021

Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle

scientific article

Resolving heterogeneous macromolecular assemblies by Orbitrap-based single-particle charge detection mass spectrometry

scientific article published on 09 March 2020

Restoring the natural tropism of AAV2 vectors for human liver

scientific article published on 01 September 2020

Single Amino Acid Modification of Adeno-Associated Virus Capsid Changes Transduction and Humoral Immune Profiles ⬇️

scientific article published on May 16, 2012

Single amino acid changes can influence titer, heparin binding, and tissue tropism in different adeno-associated virus serotypes

scientific article

Site-Directed Mutagenesis Improves the Transduction Efficiency of Capsid Library-Derived Recombinant AAV Vectors

scientific article published on 13 March 2020

Site-Directed Mutagenesis of Surface-Exposed Lysine Residues Leads to Improved Transduction by AAV2, But Not AAV8, Vectors in Murine Hepatocytes In Vivo

scientific article

Speeding up proton transfer in a fast enzyme: kinetic and crystallographic studies on the effect of hydrophobic amino acid substitutions in the active site of human carbonic anhydrase II

scientific article

Structural Characterization of Cuta- and Tusavirus: Insight into Protoparvoviruses Capsid Morphology

scientific article published on 17 June 2020

Structural Characterization of H-1 Parvovirus: Comparison of Infectious Virions to Empty Capsids ⬇️

scientific article published on February 28, 2013

Structural Characterization of the Dual Glycan Binding Adeno-Associated Virus Serotype 6 ⬇️

scientific article published on September 22, 2010

Structural Insight into the Unique Properties of Adeno-Associated Virus Serotype 9

scientific article

Structural Insights into Adeno-Associated Virus Serotype 5

scientific article

Structural Insights into Human Bocaparvoviruses

scientific article published on 22 March 2017

Structural Insights into the Extracytoplasmic Thiamine-Binding Lipoprotein p37 of Mycoplasma hyorhinis

scientific article

Structural Studies of Adeno-Associated Virus Serotype 8 Capsid Transitions Associated with Endosomal Trafficking ⬇️

scientific article published on September 7, 2011

Structural and Kinetic Study of the Extended Active Site for Proton Transfer in Human Carbonic Anhydrase II

scientific article

Structural and biophysical characterization of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2: insights into engineering thermostable enzymes for CO2 sequestration

scientific article

Structural and mutational characterization of L-carnitine binding to human carnitine acetyltransferase

scientific article

Structural characterization of a bat Adeno-associated virus capsid

scientific article published on 06 June 2020

Structural determinants of tissue tropism and in vivo pathogenicity for the parvovirus minute virus of mice

scientific article

Structural determination of a partially hemihedrally twinned actin crystal

scientific article

Structural insights and functional implications of choline acetyltransferase

scientific journal article

Structurally mapping the diverse phenotype of adeno-associated virus serotype 4.

scientific article

Structure and Dynamics of Adeno-Associated Virus Serotype 1 VP1-Unique N-Terminal Domain and Its Role in Capsid Trafficking ⬇️

scientific article published on February 20, 2013

Structure comparison of the chimeric AAV2.7m8 vector with parental AAV2

scientific article published on 16 December 2019

Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37

scientific article

Structure of Adeno-Associated Virus Serotype 8, a Gene Therapy Vector

scientific article

Structure of a monoclinic polymorph of human carbonic anhydrase II with a doubled a axis

scientific article

Structure of adeno-associated virus serotype 5.

scientific article published on April 2004

Structure of adeno-associated virus type 4.

scientific article

Structure of an enteric pathogen, bovine parvovirus

scientific article

Structure of human carnitine acetyltransferase. Molecular basis for fatty acyl transfer

scientific article (publication date: 11 April 2003)

Structure of human salivary alpha-amylase crystallized in a C-centered monoclinic space group

scientific article published on 27 January 2006

Structure of neurotropic adeno-associated virus AAVrh.8.

scientific article

Structure of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae bound to an allophenylnorstatine-based inhibitor

scientific article

Structure of the unbound form of HIV-1 subtype A protease: comparison with unbound forms of proteases from other HIV subtypes

scientific article

Structure-function correlation of G6, a novel small molecule inhibitor of Jak2: indispensability of the stilbenoid core.

scientific article

Structure-guided evolution of antigenically distinct adeno-associated virus variants for immune evasion

scientific article published on 30 May 2017

Structures of Host Range-Controlling Regions of the Capsids of Canine and Feline Parvoviruses and Mutants ⬇️

scientific article published on November 1, 2003

Sub-2 Å Ewald curvature corrected structure of an AAV2 capsid variant

scientific article published in Nature Communications

Surface loop dynamics in adeno-associated virus capsid assembly

scientific article published on 26 March 2008

Surface-exposed adeno-associated virus Vp1-NLS capsid fusion protein rescues infectivity of noninfectious wild-type Vp2/Vp3 and Vp3-only capsids but not that of fivefold pore mutant virions

scientific article published on 16 May 2007

Synchrotron Radiation Provides a Plausible Explanation for the Generation of a Free Radical Adduct of Thioxolone in Mutant Carbonic Anhydrase II ⬇️

scientific article published on October 7, 2010

Targeting Photoreceptors via Intravitreal Delivery Using Novel, Capsid-Mutated AAV Vectors ⬇️

scientific article published on April 26, 2013

The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice

scientific article

The Good That Viruses Do.

scientific article published on September 2017

The Structure of Carbonic Anhydrase IX Is Adapted for Low-pH Catalysis

scientific article

The Threefold Protrusions of Adeno-Associated Virus Type 8 Are Involved in Cell Surface Targeting as Well as Postattachment Processing ⬇️

scientific article published on June 20, 2012

The family Parvoviridae

scientific article

The ins and outs of viral infection: keystone meeting review

scientific article published on 25 September 2014

The refined atomic structure of carbonic anhydrase II at 1.05 A resolution: implications of chemical rescue of proton transfer

scientific article

The role of the adeno-associated virus capsid in gene transfer

scientific article published on January 2008

The structure of AAVrh32.33, a novel gene delivery vector

scientific article

Thermal Stability as a Determinant of AAV Serotype Identity

scientific article

Tunable protease-activatable virus nanonodes

scientific article

Twenty-Five Years of Structural Parvovirology.

scientific article

Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression

scientific article published on 02 October 2008

Vector design Tour de Force: integrating combinatorial and rational approaches to derive novel adeno-associated virus variants

scientific article

X-ray crystallographic studies reveal that the incorporation of spacer groups in carbonic anhydrase inhibitors causes alternate binding modes

scientific article

XVIIth International Parvovirus Workshop

scientific article published on 26 February 2019

p37 Induces tumor invasiveness

scientific article published in July 2005

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