List of works - Martin Egli

2'-Fluoro RNA shows increased Watson-Crick H-bonding strength and stacking relative to RNA: evidence from NMR and thermodynamic data

scientific article

2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H

scientific article published on April 2006

2'-O-[2-(methylthio)ethyl]-modified oligonucleotide: an analogue of 2'-O-[2-(methoxy)-ethyl]-modified oligonucleotide with improved protein binding properties and high binding affinity to target RNA

scientific article

2'-O-[2-[2-(N,N-dimethylamino)ethoxy]ethyl] modified oligonucleotides: symbiosis of charge interaction factors and stereoelectronic effects

scientific article (publication date: 12 June 2003)

2'-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity

scientific article

5-methyltetrahydrofolate is bound in intersubunit areas of rat liver folate-binding protein glycine N-methyltransferase

scientific article

A Bridging Water Anchors the Tethered 5-(3-Aminopropyl)-2′-deoxyuridine Amine in the DNA Major Groove Proximate to the N+2 C·G Base Pair: Implications for Formation of Interstrand 5′-GNC-3′ Cross-Links by Nitrogen Mustards † , ‡

scientific article

A Nucleotide-Analogue-Induced Gain of Function Corrects the Error-Prone Nature of Human DNA Polymerase iota ⬇️

scientific article published on June 14, 2012

A circadian clock nanomachine that runs without transcription or translation ⬇️

scientific article published on April 6, 2013

A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ

scientific article

A conformational transition in the structure of a 2′-thiomethyl-modified DNA visualized at high resolution

scientific article

Altering the Electrostatic Potential in the Major Groove: Thermodynamic and Structural Characterization of 7-Deaza-2′-deoxyadenosine:dT Base Pairing in DNA ⬇️

scientific article published on November 8, 2011

Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs

scientific article

An Exocyclic Methylene Group Acts As a Bioisostere of the 2′-Oxygen Atom in LNA ⬇️

scientific article published on October 27, 2010

An aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injury

scientific article

An arginine tetrad as mediator of input-dependent and input-independent ATPases in the clock protein KaiC.

scientific article

Analysis of KaiA-KaiC protein interactions in the cyano-bacterial circadian clock using hybrid structural methods

scientific journal article

Architecture and mechanism of the central gear in an ancient molecular timer

scientific article

Backbone Flexibility Influences Nucleotide Incorporation by Human Translesion DNA Polymerase η opposite Intrastrand Cross-Linked DNA.

scientific article published on December 2015

Backbone-base inclination as a fundamental determinant of nucleic acid self- and cross-pairing

scientific article

Basis of Miscoding of the DNA Adduct N2,3-Ethenoguanine by Human Y-family DNA Polymerases

scientific article

Bypass of Aflatoxin B1 Adducts by the Sulfolobus solfataricus DNA Polymerase IV ⬇️

scientific article published on July 26, 2011

Combined SAXS/EM Based Models of the S. elongatus Post-Translational Circadian Oscillator and its Interactions with the Output His-Kinase SasA

scientific article

CryoEM and Molecular Dynamics of the Circadian KaiB–KaiC Complex Indicates That KaiB Monomers Interact with KaiC and Block ATP Binding Clefts

scientific article

Crystal Structure of the Redox-Active Cofactor Dibromothymoquinone Bound to Circadian Clock Protein KaiA and Structural Basis for Dibromothymoquinone’s Ability to Prevent Stimulation of KaiC Phosphorylation by KaiA ⬇️

scientific article published on October 5, 2012

Crystal structure of a luteoviral RNA pseudoknot and model for a minimal ribosomal frameshifting motif

scientific article published on August 2005

Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles

scientific article

Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme

scientific article

Crystallization and preliminary X-ray analysis of Escherichia coli RNase HI-dsRNA complexes

scientific article published on 17 January 2007

Crystallographic studies of chemically modified nucleic acids: a backward glance

scientific article

DNA-cation interactions: quo vadis?

scientific article

Dephosphorylation of the Core Clock Protein KaiC in the Cyanobacterial KaiABC Circadian Oscillator Proceeds via an ATP Synthase Mechanism

scientific article

Determining Functional Aptamer-Protein Interaction by Biolayer Interferometry

scientific article

Differential Furanose Selection in the Active Sites of Archaeal DNA Polymerases Probed by Fixed-Conformation Nucleotide Analogues ⬇️

scientific article published on October 30, 2012

Diffraction techniques in structural biology

scientific article

Direct observation of a cytosine analogue that forms five hydrogen bonds to guanosine: guanidino G-clamp

scientific article

Effects of N2,N2 -dimethylguanosine on RNA structure and stability: Crystal structure of an RNA duplex with tandem m2 2G:A pairs

scientific article

Elucidating the ticking of an in vitro circadian clockwork

scientific article

Face-to-face and edge-to-face pi-pi interactions in a synthetic DNA hairpin with a stilbenediether linker

scientific article

Gene silencing activity of siRNAs with a ribo-difluorotoluyl nucleotide

scientific article

Generating Crystallographic Models of DNA Dodecamers from Structures of RNase H:DNA Complexes

scientific article

Human Cytochrome P450 21A2, the Major Steroid 21-Hydroxylase: STRUCTURE OF THE ENZYME·PROGESTERONE SUBSTRATE COMPLEX AND RATE-LIMITING C-H BOND CLEAVAGE

scientific journal article

Hydrogen bonding of 7,8-dihydro-8-oxodeoxyguanosine with a charged residue in the little finger domain determines miscoding events in Sulfolobus solfataricus DNA polymerase Dpo4

scientific article

Identification of key phosphorylation sites in the circadian clock protein KaiC by crystallographic and mutagenetic analyses

scholarly article

Insertion of dNTPs Opposite the 1, N 2 -Propanodeoxyguanosine Adduct by Sulfolobus solfataricus P2 DNA Polymerase IV † ‡

scientific article

Insights from Crystal Structures into the Opposite Effects on RNA Affinity Caused by the S- and R-6′-Methyl Backbone Modifications of 3′-Fluoro Hexitol Nucleic Acid ⬇️

scientific article published on December 29, 2011

Insights from crystallographic studies into the structural and pairing properties of nucleic acid analogs and chemically modified DNA and RNA oligonucleotides

scientific article published on January 2007

Insights into RNA/DNA hybrid recognition and processing by RNase H from the crystal structure of a non-specific enzyme-dsDNA complex

scientific article

Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Nonionic Modifications Better than DNA

scientific article

Intramolecular regulation of phosphorylation status of the circadian clock protein KaiC

scientific article

Intricate protein-protein interactions in the cyanobacterial circadian clock

scientific article

Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase

scientific article

Leukotriene Biosynthesis Inhibitor MK886 Impedes DNA Polymerase Activity ⬇️

scientific article published on January 31, 2013

Limits of RNA 2'-OH Mimicry by Fluorine: Crystal Structure of Bacillus halodurans RNase H Bound to a 2'-FRNA:DNA Hybrid

scientific article

Loop–Loop Interactions Regulate KaiA-Stimulated KaiC Phosphorylation in the Cyanobacterial KaiABC Circadian Clock

scientific article

Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase η.

scientific article published on 6 January 2016

Mechanisms of Insertion of dCTP and dTTP Opposite the DNA lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase η

scientific article

Metabolic compensation and circadian resilience in prokaryotic cyanobacteria

scientific article

Metal ions and flexibility in a viral RNA pseudoknot at atomic resolution

scientific article

Metal-ion dependence of the active-site conformation of the translesion DNA polymerase Dpo4 fromSulfolobus solfataricus

scientific article

Molecular basis of selectivity of nucleoside triphosphate incorporation opposite O6-benzylguanine by sulfolobus solfataricus DNA polymerase Dpo4: steady-state and pre-steady-state kinetics and x-ray crystallography of correct and incorrect pairing

scientific article

Nature of KaiB-KaiC binding in the cyanobacterial circadian oscillator ⬇️

scientific article published on February 6, 2013

Nucleic acid crystallography: current progress

scientific article

Pairing Geometry of the Hydrophobic Thymine Analogue 2,4-Difluorotoluene in Duplex DNA as Analyzed by X-ray Crystallography

scientific article

Protein-Protein Interactions in the Cyanobacterial Circadian Clock: Structure of KaiA Dimer in Complex with C-Terminal KaiC Peptides at 2.8 Å Resolution

scientific article

Recent Structural Insights into Cytochrome P450 Function

scientific article

Recognition of O6 -benzyl-2′-deoxyguanosine by a perimidinone-derived synthetic nucleoside: a DNA interstrand stacking interaction ⬇️

scientific article published on June 8, 2013

Replication Bypass of the trans-4-Hydroxynonenal-Derived (6S,8R,11S)-1,N2-Deoxyguanosine DNA Adduct by the Sulfolobus solfataricus DNA Polymerase IV ⬇️

scientific article published on February 7, 2012

Replication of N2,3‐Ethenoguanine by DNA Polymerases ⬇️

scientific article published on April 4, 2012

Research Resource: Correlating Human Cytochrome P450 21A2 Crystal Structure and Phenotypes of Mutations in Congenital Adrenal Hyperplasia

scientific article

Ring-Opening of the γ-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4 ⬇️

scientific article published on August 16, 2013

Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase η in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2'-deoxyguanosine

scientific article published on 6 May 2015

Selective Modulation of DNA Polymerase Activity by Fixed‐Conformation Nucleoside Analogues ⬇️

scientific article published on October 4, 2010

Selenium-assisted nucleic acid crystallography: use of phosphoroselenoates for MAD phasing of a DNA structure

scientific article

Stabilizing contributions of sulfur-modified nucleotides: crystal structure of a DNA duplex with 2'-O-[2-(methoxy)ethyl]-2-thiothymidines

scientific article

Structural Basis for Proficient Incorporation of dTTP Opposite O6-Methylguanine by Human DNA Polymerase ι

scientific article

Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5'-C-Methyl Pyrimidine-Modified Oligonucleotides

scientific article

Structural and Functional Analysis of Sulfolobus solfataricus Y-Family DNA Polymerase Dpo4-Catalyzed Bypass of the Malondialdehyde−Deoxyguanosine Adduct ,

scientific article

Structural and Functional Elucidation of the Mechanism Promoting Error-prone Synthesis by Human DNA Polymerase Opposite the 7,8-Dihydro-8-oxo-2'-deoxyguanosine Adduct

scientific article

Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase η.

scientific article published on 16 May 2016

Structural and kinetic analysis of nucleoside triphosphate incorporation opposite an abasic site by human translesion DNA polymerase η.

scientific article

Structural and kinetic basis of steroid 17α,20-lyase activity in teleost fish cytochrome P450 17A1 and its absence in cytochrome P450 17A2.

scientific article

Structural insights into a circadian oscillator

scientific article

Structural model of the circadian clock KaiB–KaiC complex and mechanism for modulation of KaiC phosphorylation

scientific article

Structure and activity of Y-class DNA polymerase DPO4 from Sulfolobus solfataricus with templates containing the hydrophobic thymine analog 2,4-difluorotoluene

scientific article

Structure and nuclease resistance of 2′,4′-constrained 2′-O-methoxyethyl (cMOE) and 2′-O-ethyl (cEt) modified DNAs

scientific article

Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs

scientific article

Structure-Function Relationships in Miscoding by Sulfolobus solfataricus DNA Polymerase Dpo4: GUANINE N2,N2-DIMETHYL SUBSTITUTION PRODUCES INACTIVE AND MISCODING POLYMERASE COMPLEXES

scientific article

Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase

scientific article

Syntheses of 4'-thioribonucleosides and thermodynamic stability and crystal structure of RNA oligomers with incorporated 4'-thiocytosine

scientific article

Synthesis and Antisense Properties of Fluoro Cyclohexenyl Nucleic Acid (F-CeNA), a Nuclease Stable Mimic of 2′-Fluoro RNA

scientific article

Synthesis, Improved Antisense Activity and Structural Rationale for the Divergent RNA Affinities of 3′-Fluoro Hexitol Nucleic Acid (FHNA and Ara-FHNA) Modified Oligonucleotides ⬇️

scientific article published on September 22, 2011

The Conformationally Constrained N-Methanocarba-dT Analogue Adopts an Unexpected C4′-exo Sugar Pucker in the Structure of a DNA Hairpin ⬇️

scientific article published on March 20, 2012

The Steric Hypothesis for DNA Replication and Fluorine Hydrogen Bonding Revisited in Light of Structural Data ⬇️

scientific article published on April 23, 2012

The cyanobacterial circadian system: from biophysics to bioevolution

scientific article

The long and winding road to the structure of homo-DNA.

scientific article published on 3 October 2006

The many twists and turns of DNA: template, telomere, tool, and target

scientific article

The structural diversity of artificial genetic polymers

scientific article

Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA

scientific article

Unique gene-silencing and structural properties of 2'-fluoro-modified siRNAs

scientific article

Use of Chromophoric Ligands to Visually Screen Co‐Crystals of Putative Protein‐Nucleic Acid Complexes ⬇️

scientific article published on September 1, 2011

Versatility of Y-family Sulfolobus solfataricus DNA Polymerase Dpo4 in Translesion Synthesis Past Bulky N2-Alkylguanine Adducts

scientific article

Visualizing a circadian clock protein: crystal structure of KaiC and functional insights

scientific article

Why does TNA cross-pair more strongly with RNA than with DNA? an answer from X-ray analysis

scientific article

List of works by Martin Egli

2'-Fluoro RNA shows increased Watson-Crick H-bonding strength and stacking relative to RNA: evidence from NMR and thermodynamic data

2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H

2'-O-[2-(methylthio)ethyl]-modified oligonucleotide: an analogue of 2'-O-[2-(methoxy)-ethyl]-modified oligonucleotide with improved protein binding properties and high binding affinity to target RNA

2'-O-[2-[2-(N,N-dimethylamino)ethoxy]ethyl] modified oligonucleotides: symbiosis of charge interaction factors and stereoelectronic effects

2'-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity

5-methyltetrahydrofolate is bound in intersubunit areas of rat liver folate-binding protein glycine N-methyltransferase

A Bridging Water Anchors the Tethered 5-(3-Aminopropyl)-2′-deoxyuridine Amine in the DNA Major Groove Proximate to the N+2 C·G Base Pair: Implications for Formation of Interstrand 5′-GNC-3′ Cross-Links by Nitrogen Mustards † , ‡

A Nucleotide-Analogue-Induced Gain of Function Corrects the Error-Prone Nature of Human DNA Polymerase iota ⬇️

A circadian clock nanomachine that runs without transcription or translation ⬇️

A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ

A conformational transition in the structure of a 2′-thiomethyl-modified DNA visualized at high resolution

Altering the Electrostatic Potential in the Major Groove: Thermodynamic and Structural Characterization of 7-Deaza-2′-deoxyadenosine:dT Base Pairing in DNA ⬇️

Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs

An Exocyclic Methylene Group Acts As a Bioisostere of the 2′-Oxygen Atom in LNA ⬇️

An aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injury

An arginine tetrad as mediator of input-dependent and input-independent ATPases in the clock protein KaiC.

Analysis of KaiA-KaiC protein interactions in the cyano-bacterial circadian clock using hybrid structural methods

Architecture and mechanism of the central gear in an ancient molecular timer

Backbone Flexibility Influences Nucleotide Incorporation by Human Translesion DNA Polymerase η opposite Intrastrand Cross-Linked DNA.

Backbone-base inclination as a fundamental determinant of nucleic acid self- and cross-pairing

Basis of Miscoding of the DNA Adduct N2,3-Ethenoguanine by Human Y-family DNA Polymerases

Bypass of Aflatoxin B1 Adducts by the Sulfolobus solfataricus DNA Polymerase IV ⬇️

Combined SAXS/EM Based Models of the S. elongatus Post-Translational Circadian Oscillator and its Interactions with the Output His-Kinase SasA

CryoEM and Molecular Dynamics of the Circadian KaiB–KaiC Complex Indicates That KaiB Monomers Interact with KaiC and Block ATP Binding Clefts

Crystal Structure of the Redox-Active Cofactor Dibromothymoquinone Bound to Circadian Clock Protein KaiA and Structural Basis for Dibromothymoquinone’s Ability to Prevent Stimulation of KaiC Phosphorylation by KaiA ⬇️

Crystal structure of a luteoviral RNA pseudoknot and model for a minimal ribosomal frameshifting motif

Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles

Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme

Crystallization and preliminary X-ray analysis of Escherichia coli RNase HI-dsRNA complexes

Crystallographic studies of chemically modified nucleic acids: a backward glance

DNA-cation interactions: quo vadis?

Dephosphorylation of the Core Clock Protein KaiC in the Cyanobacterial KaiABC Circadian Oscillator Proceeds via an ATP Synthase Mechanism

Determining Functional Aptamer-Protein Interaction by Biolayer Interferometry

Differential Furanose Selection in the Active Sites of Archaeal DNA Polymerases Probed by Fixed-Conformation Nucleotide Analogues ⬇️

Diffraction techniques in structural biology

Direct observation of a cytosine analogue that forms five hydrogen bonds to guanosine: guanidino G-clamp

Effects of N2,N2 -dimethylguanosine on RNA structure and stability: Crystal structure of an RNA duplex with tandem m2 2G:A pairs

Elucidating the ticking of an in vitro circadian clockwork

Face-to-face and edge-to-face pi-pi interactions in a synthetic DNA hairpin with a stilbenediether linker

Gene silencing activity of siRNAs with a ribo-difluorotoluyl nucleotide

Generating Crystallographic Models of DNA Dodecamers from Structures of RNase H:DNA Complexes

Human Cytochrome P450 21A2, the Major Steroid 21-Hydroxylase: STRUCTURE OF THE ENZYME·PROGESTERONE SUBSTRATE COMPLEX AND RATE-LIMITING C-H BOND CLEAVAGE

Hydrogen bonding of 7,8-dihydro-8-oxodeoxyguanosine with a charged residue in the little finger domain determines miscoding events in Sulfolobus solfataricus DNA polymerase Dpo4

Identification of key phosphorylation sites in the circadian clock protein KaiC by crystallographic and mutagenetic analyses

Insertion of dNTPs Opposite the 1, N 2 -Propanodeoxyguanosine Adduct by Sulfolobus solfataricus P2 DNA Polymerase IV † ‡

Insights from Crystal Structures into the Opposite Effects on RNA Affinity Caused by the S- and R-6′-Methyl Backbone Modifications of 3′-Fluoro Hexitol Nucleic Acid ⬇️

Insights from crystallographic studies into the structural and pairing properties of nucleic acid analogs and chemically modified DNA and RNA oligonucleotides

Insights into RNA/DNA hybrid recognition and processing by RNase H from the crystal structure of a non-specific enzyme-dsDNA complex

Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Nonionic Modifications Better than DNA

Intramolecular regulation of phosphorylation status of the circadian clock protein KaiC

Intricate protein-protein interactions in the cyanobacterial circadian clock

Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase

Leukotriene Biosynthesis Inhibitor MK886 Impedes DNA Polymerase Activity ⬇️

Limits of RNA 2'-OH Mimicry by Fluorine: Crystal Structure of Bacillus halodurans RNase H Bound to a 2'-FRNA:DNA Hybrid

Loop–Loop Interactions Regulate KaiA-Stimulated KaiC Phosphorylation in the Cyanobacterial KaiABC Circadian Clock

Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase η.

Mechanisms of Insertion of dCTP and dTTP Opposite the DNA lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase η

Metabolic compensation and circadian resilience in prokaryotic cyanobacteria

Metal ions and flexibility in a viral RNA pseudoknot at atomic resolution

Metal-ion dependence of the active-site conformation of the translesion DNA polymerase Dpo4 fromSulfolobus solfataricus

Molecular basis of selectivity of nucleoside triphosphate incorporation opposite O6-benzylguanine by sulfolobus solfataricus DNA polymerase Dpo4: steady-state and pre-steady-state kinetics and x-ray crystallography of correct and incorrect pairing

Nature of KaiB-KaiC binding in the cyanobacterial circadian oscillator ⬇️

Nucleic acid crystallography: current progress

Pairing Geometry of the Hydrophobic Thymine Analogue 2,4-Difluorotoluene in Duplex DNA as Analyzed by X-ray Crystallography

Protein-Protein Interactions in the Cyanobacterial Circadian Clock: Structure of KaiA Dimer in Complex with C-Terminal KaiC Peptides at 2.8 Å Resolution

Recent Structural Insights into Cytochrome P450 Function

Recognition of O6 -benzyl-2′-deoxyguanosine by a perimidinone-derived synthetic nucleoside: a DNA interstrand stacking interaction ⬇️

Replication Bypass of the trans-4-Hydroxynonenal-Derived (6S,8R,11S)-1,N2-Deoxyguanosine DNA Adduct by the Sulfolobus solfataricus DNA Polymerase IV ⬇️

Replication of N2,3‐Ethenoguanine by DNA Polymerases ⬇️

Research Resource: Correlating Human Cytochrome P450 21A2 Crystal Structure and Phenotypes of Mutations in Congenital Adrenal Hyperplasia

Ring-Opening of the γ-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4 ⬇️

Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase η in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2'-deoxyguanosine

Selective Modulation of DNA Polymerase Activity by Fixed‐Conformation Nucleoside Analogues ⬇️

Selenium-assisted nucleic acid crystallography: use of phosphoroselenoates for MAD phasing of a DNA structure

Stabilizing contributions of sulfur-modified nucleotides: crystal structure of a DNA duplex with 2'-O-[2-(methoxy)ethyl]-2-thiothymidines

Structural Basis for Proficient Incorporation of dTTP Opposite O6-Methylguanine by Human DNA Polymerase ι

Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5'-C-Methyl Pyrimidine-Modified Oligonucleotides

Structural and Functional Analysis of Sulfolobus solfataricus Y-Family DNA Polymerase Dpo4-Catalyzed Bypass of the Malondialdehyde−Deoxyguanosine Adduct ,

Structural and Functional Elucidation of the Mechanism Promoting Error-prone Synthesis by Human DNA Polymerase Opposite the 7,8-Dihydro-8-oxo-2'-deoxyguanosine Adduct