List of works by Jamie Rossjohn

221 Structure-function characterization of type I interferon receptor signaling regulation

A BAFF antagonist suppresses experimental autoimmune encephalomyelitis by targeting cell-mediated and humoral immune responses

scientific article published on 16 August 2006

A Green Fluorescent Protein Containing a QFG Tri-Peptide Chromophore: Optical Properties and X-Ray Crystal Structure

scientific article

A Molecular Basis for NKT Cell Recognition of CD1d-Self-Antigen

scientific article

A Molecular Basis for the Exquisite CD1d-Restricted Antigen Specificity and Functional Responses of Natural Killer T Cells

scientific article

A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism

scientific article

A Naturally Selected Dimorphism within the HLA-B44 Supertype Alters Class I Structure, Peptide Repertoire, and T Cell Recognition

scientific article

A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02-Expressing Individuals

scientific article published on 19 August 2020

A T Cell Receptor Locus Harbors a Malaria-Specific Immune Response Gene

scientific article published on 10 November 2017

A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule

scientific article

A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids

scientific article published in Nature Communications

A TCR β-Chain Motif Biases toward Recognition of Human CD1 Proteins

scientific article published on 06 November 2019

A Viral Immunoevasin Controls Innate Immunity by Targeting the Prototypical Natural Killer Cell Receptor Family

scientific article

A biased view toward celiac disease

scientific article published on 23 March 2016

A biophysical analysis of the tetratricopeptide repeat-rich mitochondrial import receptor, Tom70, reveals an elongated monomer that is inherently flexible, unstable, and unfolds via a multistate pathway

scientific article

A bird's eye view of NK cell receptor interactions with their MHC class I ligands

scientific article published on September 2015

A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1

scientific article published on 01 December 2019

A common fold mediates vertebrate defense and bacterial attack

scientific article

A conserved energetic footprint underpins recognition of Human Leukocyte Antigen-E by two distinct αβ T cell receptors

scientific article published on 25 September 2017

A conserved human T cell population targets mycobacterial antigens presented by CD1b

scientific article

A homology model for the human theta-class glutathione transferase T1-1.

scientific article

A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling.

scientific article published on 13 March 2017

A long, naturally presented immunodominant epitope from NY-ESO-1 tumor antigen: implications for cancer vaccine design

scientific article

A microfluidic-SERSplatform for isolation and immuno-phenotyping of antigen specific T-cells

A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR.

scientific article published on 31 March 2008

A mixed disulfide bond in bacterial glutathione transferase: functional and evolutionary implications

scientific article

A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis

scientific article

A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells

scientific article

A molecular basis of human T cell receptor autoreactivity toward self-phospholipids

scientific article

A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells

scientific article

A mortise-tenon joint in the transmembrane domain modulates autotransporter assembly into bacterial outer membranes

scientific article

A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity

scientific article published on 29 July 2019

A structural and functional investigation of a novel protein from Mycobacterium smegmatis implicated in mycobacterial macrophage survivability

scientific article

A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease

scientific article

A structural basis for antigen presentation by the MHC class Ib molecule, Qa-1b

scientific article

A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition.

scientific article

A structural basis for selection of the mucosal associated invariant T cell receptor in MR1-restricted antigen recognition

A structural basis for the pH-dependent increase in fluorescence efficiency of chromoproteins

scientific article

A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity

scientific article

A structural basis for varied αβ TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule

scientific article

A structural characterization of the isoniazidMycobacterium tuberculosisdrug target, Rv2971, in its unliganded form

scientific article

A structural perspective on MHC class Ib molecules in adaptive immunity

scientific article published on 21 July 2006

A structural voyage toward an understanding of the MHC-I-restricted immune response: lessons learned and much to be learned

scientific article

A structurally derived consensus pattern for theta class glutathione transferases

A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44

scientific article published on 29 July 2019

A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands

A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage.

scientific article published on 26 September 2016

AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP.

scientific article

Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1

scientific article published on 01 July 2020

Acute emergence and reversion of influenza A virus quasispecies within CD8+ T cell antigenic peptides

scientific article

Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands

scientific article published on 08 October 2009

Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands

scientific article published on December 2009

Aerolysin and pertussis toxin share a common receptor-binding domain

scientific article

Aerolysin--a paradigm for membrane insertion of beta-sheet protein toxins?

scientific article published in January 1998

Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses

scientific article

Allelic polymorphism in the T cell receptor and its impact on immune responses

scientific article

Alloreactivity

scientific article published in January 2013

Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-dependent structural mimicry

scientific article published on 8 September 2006

Alternative cross-priming through CCL17-CCR4-mediated attraction of CTLs toward NKT cell-licensed DCs.

scientific article published on 28 February 2010

Amino acid substitutions around the chromophore of the chromoprotein Rtms5 influence polypeptide cleavage

scientific article published on 28 December 2005

An extensive antigenic footprint underpins immunodominant TCR adaptability against a hypervariable viral determinant

scientific article

An overview on the identification of MAIT cell antigens.

scientific article published on 14 April 2018

Antagonism of antiviral and allogeneic activity of a human public CTL clonotype by a single altered peptide ligand: implications for allograft rejection

scientific article

Antigen Specificity of Type I NKT Cells Is Governed by TCR β-Chain Diversity.

scientific article published on 30 September 2015

Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor

scientific article published on 21 May 2009

Antigen recognition by CD1d-restricted NKT T cell receptors.

scientific article

Antigen-driven patterns of TCR bias are shared across diverse outcomes of human hepatitis C virus infection

scientific article published on 15 December 2010

Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

scientific article

Arresting pore formation of a cholesterol-dependent cytolysin by disulfide trapping synchronizes the insertion of the transmembrane beta-sheet from a prepore intermediate

scientific article

Atypical TRAV1-2- T cell receptor recognition of the antigen-presenting molecule MR1

scientific article published on 14 August 2020

Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.

scientific article published on 15 February 2016

Author Correction: Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1

scientific article published on 02 March 2020

Beta-testing NKT cell self-reactivity

scientific article published on 16 November 2011

Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease

scientific article

Bimolecular interaction of insulin-like growth factor (IGF) binding protein-2 with alphavbeta3 negatively modulates IGF-I-mediated migration and tumor growth.

scientific article published on February 2004

Broad CD8 T cell cross-recognition of distinct influenza A strains in humans

scientific article published in Nature Communications

Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells

scientific article

CD1a on Langerhans cells controls inflammatory skin disease.

scientific article published on 22 August 2016

CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens

scientific article published on 22 December 2013

CD1d antigen presentation: treats for NKT cells

CD1d protein structure determines species-selective antigenicity of isoglobotrihexosylceramide (iGb3) to invariant NKT cells

scientific article

CD1d-lipid antigen recognition by the γδ TCR

scientific article

CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor

scientific article

CD4 + T cell–mediated HLA class II cross-restriction in HIV controllers

article

CD8<sup>+</sup> T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph

scientific article published on 18 May 2021

CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence

scientific article

CTL recognition of a bulged viral peptide involves biased TCR selection

scientific article published in September 2005

Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph

scientific article published on 06 December 2019

Circulating gluten-specific FOXP3+CD39+ regulatory T cells have impaired suppressive function in patients with celiac disease.

scientific article published on 7 March 2017

Cloning, expression, purification and crystallographic studies of galectin-11 from domestic sheep (Ovis aries)

scientific article published on 28 July 2015

Cloning, expression, purification and preliminary X-ray diffraction studies of a mycobacterial protein implicated in bacterial survival in macrophages

scientific article published on 30 April 2013

Cloning, expression, purification and preliminary X-ray diffraction studies of a novel AB₅ toxin

scientific article published on 27 July 2013

Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens

scientific article published on 19 May 2015

Complete modification of TCR specificity and repertoire selection does not perturb a CD8+ T cell immunodominance hierarchy

scientific article

Comprehensive, quantitative mapping of T cell epitopes in gluten in celiac disease.

scientific article

Constraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognition

scientific article published on 23 March 2010

Correction: Article on Vaccination Reveals a Long Dominant CTL Epitope

Corrigendum: The burgeoning family of unconventional T cells

scholarly article published in Nature Immunology

Corrigendum: The burgeoning family of unconventional T cells.

scientific article

Cross-reactive CD8 + T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses

scientific article

Crystal structure and comparative functional analyses of a Mycobacterium aldo-keto reductase

scientific article

Crystal structure of HLA-G: a nonclassical MHC class I molecule expressed at the fetal-maternal interface

scientific article

Crystal structure of LipL32, the most abundant surface protein of pathogenic Leptospira spp

scientific article

Crystal structure of a Legionella pneumophila ecto -triphosphate diphosphohydrolase, a structural and functional homolog of the eukaryotic NTPDases

scientific article

Crystal structure of a UDP-glucose-specific glycosyltransferase from a Mycobacterium species

scientific article

Crystal structure of fuculose aldolase from the Antarctic psychrophilic yeast Glaciozyma antarctica PI12.

scientific article published on 27 October 2016

Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein

scientific article

Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3.

scholarly article

Crystal structures of the Lyn protein tyrosine kinase domain in its Apo- and inhibitor-bound state

scientific article

Crystallization and preliminary X-ray analysis of a bacterial glutathione transferase

scientific article published in January 1996

Crystallization and preliminary X-ray analysis of a thiol-activated cytolysin

scientific article published on 01 November 1996

Crystallization, structural determination and analysis of a novel parasite vaccine candidate: Fasciola hepatica glutathione S-transferase

scientific article

Cutting Edge: CD1a tetramers and dextramers identify human lipopeptide-specific T cells ex vivo.

scientific article published on 02 October 2013

Cytomegalovirus replication is associated with enrichment of distinct γδ T cell subsets following lung transplantation: A novel therapeutic approach?

scientific article published on 26 August 2020

Cytotoxic and regulatory roles of mucosal-associated invariant T cells in type 1 diabetes

scientific article published on 9 October 2017

DEC-205 is a cell surface receptor for CpG oligonucleotides

scientific article

Degenerate recognition of MHC class I molecules with Bw4 and Bw6 motifs by a killer cell Ig-like receptor 3DL expressed by macaque NK cells.

scientific article

Determinants of gliadin-specific T cell selection in celiac disease

scientific article

Determination of chromophore charge states in the low pH color transition of the fluorescent protein Rtms5H146S via time-dependent DFT

Dichloromethane mediated in vivo selection and functional characterization of rat glutathione S-transferase theta 1-1 variants

scientific journal article

Differential Recognition of CD1d-α-Galactosyl Ceramide by the Vβ8.2 and Vβ7 Semi-invariant NKT T Cell Receptors

scientific article

Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function

scientific article published on 19 January 2018

Discriminative T-cell receptor recognition of highly homologous HLA-DQ2-bound gluten epitopes

article by Shiva Dahal-Koirala et al published 18 January 2019 in Journal of Biological Chemistry

Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction

scholarly article

Disrupting the allosteric interaction between the Plasmodium falciparum cAMP-dependent kinase and its regulatory subunit

scientific article

Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains

scientific article

Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors

scientific article published on 20 November 2019

Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide.

scientific article published on 12 March 2018

Diverse T Cell Receptor Gene Usage in HLA-DQ8-Associated Celiac Disease Converges into a Consensus Binding Solution

scientific article

Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition

scientific article

Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells

scientific article published on 3 May 2017

Drug hypersensitivity and human leukocyte antigens of the major histocompatibility complex

scientific article published on 17 October 2011

Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells. ⬇️

scientific article published on 6 February 2017

Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity

scientific article published in July 2018

Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity.

scientific article published on 9 March 2018

EcxAB is a founding member of a new family of metalloprotease AB5 toxins with a hybrid cholera-like B subunit

scientific article

Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity

scientific article published on 16 December 2013

Effects of a local auxiliary protein on the two-dimensional affinity of a TCR-peptide MHC interaction

scientific article published on 26 June 2020

Endogenous antigen presentation impacts on T-box transcription factor expression and functional maturation of CD8+ T cells

scientific article published on 31 August 2012

Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens

scientific article published on 21 September 2020

Engineering a new C-terminal tail in the H-site of human glutathione transferase P1-1: structural and functional consequences

scientific article

Enzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila: substrate specificity and requirement for virulence

scientific article published on 12 March 2008

Epitope-specific TCR  repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides

scientific article

Erratum for O'Connor et al., Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1.

scientific article published on July 2015

Erratum: Recognition of the nonclassical MHC class I molecule H2-M3 by the receptor Ly49A regulates the licensing and activation of NK cells

scholarly article by Daniel M Andrews et al published April 2013 in Nature Immunology

Escape from highly effective public CD8+ T-cell clonotypes by HIV

scientific article published on 6 July 2011

Evaluation of the role of two conserved active-site residues in beta class glutathione S-transferases

scientific article published on October 2000

Expression, purification, crystallization and preliminary X-ray analysis of eCGP123, an extremely stable monomeric green fluorescent protein with reversible photoswitching properties.

scientific article published on 30 September 2011

Expression, purification, crystallization and preliminary X-ray characterization of a putative glycosyltransferase of the GT-A fold found in mycobacteria

scientific article published on 30 April 2008

Expression, purification, crystallization and preliminary X-ray diffraction analysis of an essential lipoprotein implicated in cell-wall biosynthesis in Mycobacteria

scientific article published on 24 November 2005

Fighting infection with your MAITs

Flow Cytometric Clinical Immunomonitoring Using Peptide-MHC Class II Tetramers: Optimization of Methods and Protocol Development

scientific article

Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection

scientific article published on 16 July 2021

Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites.

scientific article published on 10 June 2015

Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue

scientific article published on 5 March 2004

Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination

scientific article published on 29 August 2016

GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop

scientific article

Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1

scientific article published on 20 January 2020

Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8+ T cell response

scientific article published on 25 September 2017

Germline-encoded recognition of diverse glycolipids by natural killer T cells

article

HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection.

scientific article published on 16 March 2016

HLA peptide length preferences control CD8+ T cell responses

scientific article

HLA variation and disease.

scientific article published on 2 January 2018

HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8+ T cells

scientific article published on 04 August 2020

HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome

scientific article published in Nature Communications

HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants.

scientific article published on 14 September 2014

Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability

scientific article

Have we cut ourselves too short in mapping CTL epitopes?

scientific article published on 16 November 2005

High resolution structures of highly bulged viral epitopes bound to major histocompatibility complex class I. Implications for T-cell receptor engagement and T-cell immunodominance

scientific article

Highly Divergent T-cell Receptor Binding Modes Underlie Specific Recognition of a Bulged Viral Peptide bound to a Human Leukocyte Antigen Class I Molecule

scientific article

Hijacking of a Substrate-binding Protein Scaffold for use in Mycobacterial Cell Wall Biosynthesis

scientific article published on 25 April 2006

Host immunomodulatory lipids created by symbionts from dietary amino acids

scientific article published on 10 November 2021

Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity

scientific article published on 16 May 2016

Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity

scientific article published on 15 August 2016

How a Home-Grown T Cell Receptor Interacts with a Foreign Landscape

How opposites attract

Human CD8+ T cell cross-reactivity across influenza A, B and C viruses

scientific article published on 18 February 2019

Human Leukocyte Antigen Class I-Restricted Activation of CD8+ T Cells Provides the Immunogenetic Basis of a Systemic Drug Hypersensitivity

Human Mucosal-Associated Invariant T Cells in Older Individuals Display Expanded TCRαβ Clonotypes with Potent Antimicrobial Responses

scientific article published on 27 January 2020

Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products

scientific article published on 03 January 2020

Human TRAV1-2-negative MR1-restricted T cells detect S. pyogenes and alternatives to MAIT riboflavin-based antigens

scientific article published on 16 August 2016

Human and Mouse Type I Natural Killer T Cell Antigen Receptors Exhibit Different Fine Specificities for CD1d-Antigen Complex

scientific article

Human autoreactive T cells recognize CD1b and phospholipids

scientific article

Human glutathione transferase P1-1 and nitric oxide carriers; a new role for an old enzyme

scientific article

Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity

scientific article

Human leukocyte antigen-associated drug hypersensitivity

scientific article

Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activation

scientific article published on 19 August 2016

Human skin is colonized by T cells that recognize CD1a independently of lipid

scientific article published on 01 January 2021

Human theta class glutathione transferase: the crystal structure reveals a sulfate-binding pocket within a buried active site

scientific article

Human γδ T cells recognize CD1b by two distinct mechanisms

scientific article published on 31 August 2020

IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection

scientific article published on 01 November 2019

IMMUNODEFICIENCIES. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

scientific article

Identification of Native and Post-Translationally Modified HLA-B*57:01-Restricted HIV Envelope Derived Epitopes Using Immunoproteomics

scientific article published on 13 February 2018

Identification of a Membrane-Spanning Domain of the Thiol-Activated Pore-Forming ToxinClostridium perfringensPerfringolysin O: An α-Helical to β-Sheet Transition Identified by Fluorescence Spectroscopy†

scientific article published on 01 October 1998

Identification of a Potent Microbial Lipid Antigen for Diverse NKT Cells.

scientific article published on 07 August 2015

Identification of a dominant self-ligand bound to three HLA B44 alleles and the preliminary crystallographic analysis of recombinant forms of each complex

scientific article published on September 2002

Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers

scientific article published on 22 June 2015

Identification of self-antigen-specific T cells reflecting loss of tolerance in autoimmune disease underpins preventative immunotherapeutic strategies in rheumatoid arthritis

scientific article

Identification of the structural and functional domains of the large serine recombinase TnpX from Clostridium perfringens

scientific article published on 12 November 2004

Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

scientific article

Immune self-reactivity triggered by drug-modified human leukocyte antigen-peptide presentation

Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection

scientific article

Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses

scientific article published on 07 May 2018

Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin

scientific article

Insight into the basis of autonomous immunoreceptor activation

scientific article published on 25 February 2011

Interferon-ε protects the female reproductive tract from viral and bacterial infection

scientific journal article

Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition

scientific article published on 4 April 2016

Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1.

scientific article published on 20 February 2018

Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B

scientific article

Lack of heterologous cross-reactivity towards HLA-A*02:01 restricted viral epitopes is underpinned by distinct αβT cell receptor signatures

scientific article

Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations

scientific article published on 27 February 2005

Lipid and small-molecule display by CD1 and MR1.

scientific article published on 21 September 2015

Lipids hide or step aside for CD1-autoreactive T cell receptors.

scientific article

Loss of anti-viral immunity by infection with a virus encoding a cross-reactive pathogenic epitope.

scientific article

MAIT cells and MR1-antigen recognition

scientific article published on 08 May 2017

MAIT cells are depleted early but retain functional cytokine expression in HIV infection

scientific article published on 28 October 2014

MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immun

scientific article

MAIT cells protect against pulmonary Legionella longbeachae infection ⬇️

scientific article published in Nature Communications

MAITs, MR1 and vitamin B metabolites

scientific article published on 18 October 2013

MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.

scientific article published on 20 February 2017

MR1 presentation of vitamin B-based metabolite ligands.

scientific article

MR1 presents microbial vitamin B metabolites to MAIT cells

scientific article

Managing and mining protein crystallization data.

scientific article

Missense single nucleotide polymorphisms in the human T cell receptor loci control variable gene usage in the T cell repertoire

article

Molecular Imprint of Exposure to Naturally Occurring Genetic Variants of Human Cytomegalovirus on the T cell Repertoire

scientific article published on 10 February 2014

Molecular architecture of the αβ T cell receptor-CD3 complex

scientific article

Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.

scientific article published on 11 August 2017

Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses

scientific article published on 31 March 2016

Molecular basis of glutathione synthetase deficiency and a rare gene permutation event

scientific article

More than one reason to rethink the use of peptides in vaccine design

scientific article published on May 2007

Movement of a Loop in Domain 3 of Aerolysin Is Required for Channel Formation†

scientific article published on 01 January 1998

Mucosa-Associated Invariant T Cells Are Systemically Depleted in Simian Immunodeficiency Virus-Infected Rhesus Macaques

scientific article published on 24 February 2016

Mucosal-Associated Invariant T Cell Effector Function Is an Intrinsic Cell Property That Can Be Augmented by the Metabolic Cofactor α-Ketoglutarate

scientific article published in April 2021

Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in Chronic Helicobacter pylori Infection

scientific article

Mucosal-Associated Invariant T cell receptor recognition of small molecules presented by MR1.

scientific article published on 2 February 2018

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients

scientific article

Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity

scientific article published on 24 July 2020

Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals.

scientific article published on 4 May 2016

Multifunctional role of Tyr 108 in the catalytic mechanism of human glutathione transferase P1-1. Crystallographic and kinetic studies on the Y108F mutant enzyme

scientific article published on 20 May 1997

Mutational and Structural Analysis of KIR3DL1 Reveals a Lineage-Defining Allotypic Dimorphism That Impacts Both HLA and Peptide Sensitivity

scientific article

NKT TCR Recognition of CD1d- -C-Galactosylceramide

scientific article

NKT cells: the smoking gun in fungal-induced asthma?

scientific article published in October 2013

Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion

scientific article

Natural Killer T cell obsession with self-antigens

scientific article published on 4 February 2013

Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition

scientific article

Naturally processed non-canonical HLA-A*02:01 presented peptides

scientific article

New ways to turn on NKT cells

scientific article

Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility

scientific article published on 01 February 2021

O009 Fine structural and functional characterization of a unique IFNβ–Ifnar1 signaling axis

Overlapping Peptides Elicit Distinct CD8+ T Cell Responses following Influenza A Virus Infection

scientific article published on 31 August 2020

Peptide length determines the outcome of TCR/peptide-MHCI engagement

scientific article

Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry.

scientific article published on 12 March 2018

Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1.

scientific article published on 4 March 2015

Phospholipid signaling in innate immune cells.

scientific article published on 23 April 2018

Phosphorylated self-peptides alter human leukocyte antigen class I-restricted antigen presentation and generate tumor-specific epitopes

scientific article

Polymorphism in human cytomegalovirus UL40 impacts on recognition of human leukocyte antigen-E (HLA-E) by natural killer cells.

scientific article published on 18 January 2013

Post-translationally modified T cell epitopes: immune recognition and immunotherapy

scientific article published on 08 September 2009

Predisposed αβ T cell antigen receptor recognition of MHC and MHC-I like molecules?

scientific article published on 29 August 2013

Preemptive priming readily overcomes structure-based mechanisms of virus escape

scientific article

Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities

scientific article

Preliminary X-ray crystallographic studies of a newly defined human theta-class glutathione transferase.

scientific article published in January 1998

Prevention of Cytotoxic T Cell Escape Using a Heteroclitic Subdominant Viral T Cell Determinant

scientific article

Protective Efficacy of Cross-Reactive CD8+ T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation Threshold

scientific article

Public T cell receptors confer high-avidity CD4 responses to HIV controllers

scientific article published on 25 April 2016

Purification and biological characterization of soluble, recombinant mouse IFNβ expressed in insect cells

scientific article published on 6 November 2013

Rapid screening for the detection of HLA-B57 and HLA-B58 in prevention of drug hypersensitivity

scientific article

Recent advances in all-protein chromophore technology

scientific article published on January 2006

Recipient mucosal-associated invariant T cells control GVHD within the colon.

scientific article

Recognition of CD1d-restricted antigens by natural killer T cells

scientific article

Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor

scientific article

Recognition of Vitamin B Precursors and Byproducts by Mucosal Associated Invariant T Cells

scientific article

Recognition of host Clr-b by the inhibitory NKR-P1B receptor provides a basis for missing-self recognition

scientific article published in Nature Communications

Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs.

scientific article published on 10 January 2013

Recognition of nectin-2 by the natural killer cell receptor T cell immunoglobulin and ITIM domain (TIGIT).

scientific article

Recognition of the Major Histocompatibility Complex (MHC) Class Ib Molecule H2-Q10 by the Natural Killer Cell Receptor Ly49C.

scientific article published on 6 July 2016

Recognition of the nonclassical MHC class I molecule H2-M3 by the receptor Ly49A regulates the licensing and activation of NK cells.

scientific article published on 11 November 2012

Recognition of vitamin B metabolites by mucosal-associated invariant T cells

scientific article

Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions

scientific article published on 25 April 2016

Repeated infection in humans drives the clonal expansion of an adaptive γδ T cell repertoire

scientific article published in December 2021

Reply to Roudier et al.: HLA-DRB1 polymorphism, anti-citrullinated protein antibodies, and rheumatoid arthritis.

scientific article

Reversed T Cell Receptor Docking on a Major Histocompatibility Class I Complex Limits Involvement in the Immune Response

scientific article

STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function

scientific article published on 4 May 2015

Self-interaction of pneumolysin, the pore-forming protein toxin of Streptococcus pneumoniae

article

Shedding light on MHC class I antigen loading: a UV-labile peptide ligand approach

Shifting Substrate Specificity of Human Glutathione Transferase (from Class Pi to Class Alpha) by a Single Point Mutation

scientific article published on 01 November 1998

Single-Cell Approach to Influenza-Specific CD8+ T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection.

scientific article published on 27 June 2018

Site-directed mutagenesis of theProteus mirabilisglutathione transferase B1-1 G-site

scientific article published on 01 February 1998

Specificity on a knife-edge: the alphabeta T cell receptor

scientific article published on 29 September 2006

Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells.

scientific article published on 08 March 2017

Structural Basis of Subtilase Cytotoxin SubAB Assembly

scientific article

Structural and Functional Correlates of Enhanced Antiviral Immunity Generated by Heteroclitic CD8 T Cell Epitopes

scientific article

Structural and Sequence Comparisons of Quinone Oxidoreductase, ζ-Crystallin, and Glucose and Alcohol Dehydrogenases

article

Structural and biochemical characterization of the oxidoreductase NmDsbA3 from Neisseria meningitidis

scientific article

Structural and biological basis of CTL escape in coronavirus-infected mice

scientific article

Structural and regulatory diversity shape HLA-C protein expression levels

scientific article

Structural basis for a major histocompatibility complex class Ib-restricted T cell response

scientific journal article

Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses

scientific article

Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes

scientific article

Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1

scientific journal article

Structural determinants of T-cell receptor bias in immunity

scientific article published on 17 November 2006

Structural determination of lipid antigens captured at the CD1d-T-cell receptor interface

scientific article published on 17 July 2017

Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor

scientific article

Structural insight into natural killer T cell receptor recognition of CD1d

scientific article published on January 2007

Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C

scientific article published in 2021

Structural studies on HLA-G: implications for ligand and receptor binding

scientific article published on 27 October 2006

Structural studies on the alphabeta T-cell receptor

scientific article

Structure and function of the oxidoreductase DsbA1 from Neisseria meningitidis

scientific article

Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form

scientific article

Structure of the Chicken CD3  /  Heterodimer and Its Assembly with the   T Cell Receptor

scientific article

Structure, biological functions and applications of the AB5 toxins

scientific article

Structure-function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G-proteins

scientific article published on 29 June 2017

Structures of perfringolysin O suggest a pathway for activation of cholesterol-dependent cytolysins

scientific article

Structures of thermolabile mutants of human glutathione transferase P1-1

scientific article

Studies on the structure and mechanism of a bacterial protein toxin by analytical ultracentrifugation and small-angle neutron scattering.

scientific article published in November 1999

Suboptimal SARS-CoV-2-specific CD8+ T cell response associated with the prominent HLA-A*02:01 phenotype

scientific article published on 10 September 2020

Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors

scientific article

T Cell Cross-Reactivity between a Highly Immunogenic EBV Epitope and a Self-Peptide Naturally Presented by HLA-B*18:01+ Cells

scientific article

T cell allorecognition and MHC restriction--A case of Jekyll and Hyde?

scientific article published on 14 September 2007

T cell allorecognition via molecular mimicry

scientific article

T cell antigen receptor recognition of antigen-presenting molecules

scientific article published on 10 December 2014

T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.

scientific article published on 12 March 2018

T cell determinants incorporating beta-amino acid residues are protease resistant and remain immunogenic in vivo

scientific article published on September 2005

T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire

scientific article

T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease

scientific article published on 23 December 2019

T cell receptor recognition of CD1b presenting a mycobacterial glycolipid

scientific article published on 27 October 2016

T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide

scientific article published on 25 September 2005

T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8

scientific article published on 25 August 2021

T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex

scientific article published in November 2015

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

scientific article

T-cell allorecognition: a case of mistaken identity or déjà vu?

scientific article

T-cell receptor bias and immunity

scientific article published on 18 January 2008

T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease

scientific article

T-cells behaving badly: structural insights into alloreactivity and autoimmunity

scientific article published on 12 August 2008

TAP genes and immunity

scientific article published in October 2004

TCR alpha genes direct MHC restriction in the potent human T cell response to a class I-bound viral epitope

scientific article published on November 2006

TCR bias and affinity define two compartments of the CD1b-glycolipid-specific T Cell repertoire

scientific article

Targeted suppression of autoreactive CD8(+) T-cell activation using blocking anti-CD8 antibodies.

scientific article published on 17 October 2016

Targeting of a natural killer cell receptor family by a viral immunoevasin

scientific article

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects.

scientific article published on 23 July 2015

Tetrahydrolipstatin inhibition, functional analyses, and three-dimensional structure of a lipase essential for mycobacterial viability

scientific journal article

Tetramer Immunization and Selection Followed by CELLISA Screening to Generate Monoclonal Antibodies against the Mouse Cytomegalovirus m12 Immunoevasin

scientific article published on 19 August 2020

The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance

scientific article

The 1.5 A crystal structure of a prokaryote serpin: controlling conformational change in a heated environment

scientific article (publication date: April 2003)

The 1.5 Å Crystal Structure of a Prokaryote Serpin

article

The 1.6 A crystal structure of the catalytic domain of PlyB, a bacteriophage lysin active against Bacillus anthracis

scientific article

The 1.7 A crystal structure of Dronpa: a photoswitchable green fluorescent protein

scientific article published on 3 September 2006

The 2.0 angstroms crystal structure of a pocilloporin at pH 3.5: the structural basis for the linkage between color transition and halide binding

scientific article published in March 2006

The 2.0-A crystal structure of eqFP611, a far red fluorescent protein from the sea anemone Entacmaea quadricolor

scientific article

The 2.1A crystal structure of copGFP, a representative member of the copepod clade within the green fluorescent protein superfamily

scientific article published on 25 April 2006

The 2.1A crystal structure of the far-red fluorescent protein HcRed: inherent conformational flexibility of the chromophore

scientific article published on 22 March 2005

The 2.2 A crystal structure of a pocilloporin pigment reveals a nonplanar chromophore conformation

scientific article (publication date: March 2003)

The 2.7 A crystal structure of the autoinhibited human c-Fms kinase domain

scientific article

The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition

article

The Diverse Family of MR1-Restricted T Cells

The Diverse Family of MR1-Restricted T Cells

scientific article published on 5 November 2018

The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule

scientific article

The Ly49 natural killer cell receptors: a versatile tool for viral self-discrimination

scientific article published on 14 January 2014

The Mechanism of Membrane Insertion for a Cholesterol-Dependent Cytolysin

scientific article published on 01 October 1999

The N terminus of the serpin, tengpin, functions to trap the metastable native state

scientific article

The Structure and Stability of the Monomorphic HLA-G Are Influenced by the Nature of the Bound Peptide

scientific article

The Structure of the Bacterial Oxidoreductase Enzyme DsbA in Complex with a Peptide Reveals a Basis for Substrate Specificity in the Catalytic Cycle of DsbA Enzymes

scientific article

The Structure of the Cytomegalovirus-Encoded m04 Glycoprotein, a Prototypical Member of the m02 Family of Immunoevasins

scientific article

The burgeoning family of unconventional T cells

scientific article

The cellular redox environment alters antigen presentation

scientific article

The cryo-EM structure of the endocytic receptor DEC-205

scientific article published on 30 November 2020

The crystal structure of glucose dehydrogenase from Thermoplasma acidophilum

scientific article published in May 1994

The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis

scientific article

The early proximal αβ TCR signalosome specifies thymic selection outcome through a quantitative protein interaction network

scientific article published on 01 February 2019

The fidelity, occasional promiscuity, and versatility of T cell receptor recognition

scientific article published on March 2008

The heterodimeric assembly of the CD94-NKG2 receptor family and implications for human leukocyte antigen-E recognition

scientific article

The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition

scientific article

The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix

scientific article

The identification and structure of the membrane-spanning domain of the Clostridium septicum alpha toxin

scientific article

The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation

scientific article

The impact of HLA-B micropolymorphism outside primary peptide anchor pockets on the CTL response to CMV

article

The impact of a large and frequent deletion in the human TCR β locus on antiviral immunity

scientific article

The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family

scientific article

The insulin A-chain epitope recognized by human T cells is posttranslationally modified

scientific article

The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope

scientific article

The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in Rheumatoid Arthritis

scientific article published on 9 January 2018

The intracellular pathway for the presentation of vitamin B-related antigens by the antigen-presenting molecule MR1.

scientific article published on 04 April 2016

The major histocompatibility complex class Ib molecule HLA-E at the interface between innate and adaptive immunity.

scientific article

The molecular bases of δ/αβ T cell-mediated antigen recognition.

scientific article

The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C*06:02 molecule

scientific article published on 30 August 2017

The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function

scientific article published on 13 May 2020

The molecular basis underpinning the potency and specificity of MAIT cell antigens

scientific article published on 02 March 2020

The molecular mechanism of pneumolysin, a virulence factor from Streptococcus pneumoniae.

scientific article

The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins

scientific article

The peptide length specificity of some HLA class I alleles is very broad and includes peptides of up to 25 amino acids in length

article

The production and crystallization of the human leukocyte antigen class II molecules HLA-DQ2 and HLA-DQ8 complexed with deamidated gliadin peptides implicated in coeliac disease

scientific article published on 21 November 2007

The production and purification of the human T-cell receptors, the CD3epsilongamma and CD3epsilondelta heterodimers: complex formation and crystallization with OKT3, a therapeutic monoclonal antibody

scientific article

The production, purification and crystallization of a pocilloporin pigment from a reef-forming coral

scientific article published on 21 February 2003

The production, purification and crystallization of a soluble form of the nonclassical MHC HLA-G: the essential role of cobalt

scientific article published on 16 December 2005

The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state

scientific article

The shaping of T cell receptor recognition by self-tolerance

scientific article

The structural bases of direct T-cell allorecognition: implications for T-cell-mediated transplant rejection

scientific article published on 08 February 2011

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor

scientific article published on 14 October 2010

The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor

scientific article published on 20 September 2005

The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance

scientific article published in July 2004

The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerization

scientific article

The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4.

scientific article

The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution

scientific article

The three-dimensional structure of the human Pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate

scientific article

The versatility of the αβ T-cell antigen receptor

scientific article published on 28 January 2014

Tissue specificity of cross-reactive allogeneic responses by EBV EBNA3A-specific memory T cells

scientific article published in March 2011

Toll-like receptors: structural pieces of a curve-shaped puzzle

scientific article

Total Synthesis of Mycobacterium tuberculosis Dideoxymycobactin-838 and Stereoisomers: Diverse CD1a-Restricted T Cells Display a Common Hierarchy of Lipopeptide Recognition.

scientific article published on 7 December 2016

Towards identification of immune and genetic correlates of severe influenza disease in Indigenous Australians

scientific article published on 23 October 2015

Tracking the unfolding pathway of a multirepeat protein via tryptophan scanning: evidence of localized instability in the mitochondrial import receptor Tom70.

scientific article published on 27 June 2006

Transplantation Immunology

scholarly article published 2013 in Methods in Molecular Biology

Tumors reveal their secrets to cytotoxic T cells

scholarly article

Two distinct regions of the large serine recombinase TnpX are required for DNA binding and biological function

scientific article published in 2006

Two structural transitions in membrane pore formation by pneumolysin, the pore-forming toxin of Streptococcus pneumoniae.

scientific article published on May 1999

Understanding the complexity and malleability of T-cell recognition

scientific article published on 13 January 2015

Valine 10 May Act as a Driver for Product Release from the Active Site of Human Glutathione Transferase P1-1

scientific article published on 01 December 2000

Variations on the GFP chromophore: A polypeptide fragmentation within the chromophore revealed in the 2.1-A crystal structure of a nonfluorescent chromoprotein from Anemonia sulcata

scientific article

V 2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen

scientific article

X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation

scientific article

αβ T Cell Receptors Come Out Swinging

αβ T cell antigen receptor recognition of CD1a presenting self lipid ligands

scientific article

β-Amino acid-containing hybrid peptides—new opportunities in peptidomimetics

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