List of works - Jeffrey Trent

High frequency of BRAF mutations in nevi

scientific article

Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma

scientific article

Evidence for a prostate cancer susceptibility locus on the X chromosome

article

The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.

scientific article

A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma

scientific article published on 13 November 2011

Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells

scientific article published on July 2005

RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases

scientific article published on 4 November 2002

Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk

scientific article (publication date: October 2002)

Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia

scientific article published in May 2003

Alpha-methylacyl-CoA racemase: a new molecular marker for prostate cancer.

scientific article

Common sequence variants on 20q11.22 confer melanoma susceptibility

scientific article published on 18 May 2008

Integrating global gene expression and radiation survival parameters across the 60 cell lines of the National Cancer Institute Anticancer Drug Screen

scientific article published on January 2008

Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12

scientific article

Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4

scientific article

Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing

scientific article published on 25 December 2011

Genome and Transcriptome Sequencing in Prospective Metastatic Triple-Negative Breast Cancer Uncovers Therapeutic Vulnerabilities

scientific article published on November 19, 2012

Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3

scientific journal article

Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer

scientific article published on 8 August 2004

Germline alterations of the RNASEL gene, a candidate HPC1 gene at 1q25, in patients and families with prostate cancer

scientific article published on 8 April 2002

Differential responses of stress genes to low dose-rate gamma irradiation

scientific article published on April 1, 2003

Molecular classification of familial non-BRCA1/BRCA2 breast cancer

scholarly article

Toward precision medicine in glioblastoma: the promise and the challenges

scientific article published on May 2015

Molecular determinants of human uveal melanoma invasion and metastasis

scientific article published in January 2002

Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease

scientific article published on 08 July 2003

Effects of RNase L mutations associated with prostate cancer on apoptosis induced by 2',5'-oligoadenylates

scientific article published on October 15, 2003

Gene expression signature of benign prostatic hyperplasia revealed by cDNA microarray analysis

scientific article (publication date: 15 May 2002)

Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma

scientific article

Inherited genetic variant predisposes to aggressive but not indolent prostate cancer

scientific article

Toward a drug development path that targets metastatic progression in osteosarcoma.

scientific article

Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma

scientific article

Stress-specific signatures: expression profiling of p53 wild-type and -null human cells

scientific article

Advancing a clinically relevant perspective of the clonal nature of cancer

scientific article

A cryptic BAP1 splice mutation in a family with uveal and cutaneous melanoma, and paraganglioma

scientific article published in October 2012

Synthetic lethal RNAi screening identifies sensitizing targets for gemcitabine therapy in pancreatic cancer

scientific article

Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type.

scientific article published on 10 September 2015

p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas

scientific article

Genome-wide scan for prostate cancer susceptibility genes using families from the University of Michigan prostate cancer genetics project finds evidence for linkage on chromosome 17 near BRCA1.

scientific article published on December 2003

Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenib

scientific article

A genome scan for eye color in 502 twin families: most variation is due to a QTL on chromosome 15q.

scientific article

The interaction of four genes in the inflammation pathway significantly predicts prostate cancer risk

scientific article

A recurrent germline BAP1 mutation and extension of the BAP1 tumor predisposition spectrum to include basal cell carcinoma

scientific article

Localization of a novel melanoma susceptibility locus to 1p22

scientific article

Perspectives from man's best friend: National Academy of Medicine's Workshop on Comparative Oncology.

scientific article published on February 2016

Inference from Clustering with Application to Gene-Expression Microarrays

scholarly article published in 2002

Gene-expression profiling in human cutaneous melanoma

scientific article

Adrenocortical carcinoma survival rates correlated to genomic copy number variants

scientific article published in February 2008

Genome‐wide scan for prostate cancer susceptibility genes in the Johns Hopkins hereditary prostate cancer families

scientific article published on December 1, 2003

Functional evidence implicating S100P in prostate cancer progression

scientific article

A Genome-wide Association Study Reveals that Variants within the HLA Region Are Associated with Risk for Nonobstructive Azoospermia

scientific article published on April 26, 2012

Generation and analysis of melanoma SAGE libraries: SAGE advice on the melanoma transcriptome

scientific article

List of works by Jeffrey Trent

High frequency of BRAF mutations in nevi

Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma

Evidence for a prostate cancer susceptibility locus on the X chromosome

The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.

A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma

Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells

RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases

Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk

Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia

Alpha-methylacyl-CoA racemase: a new molecular marker for prostate cancer.

Common sequence variants on 20q11.22 confer melanoma susceptibility

Integrating global gene expression and radiation survival parameters across the 60 cell lines of the National Cancer Institute Anticancer Drug Screen

Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12

Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4

Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing

Genome and Transcriptome Sequencing in Prospective Metastatic Triple-Negative Breast Cancer Uncovers Therapeutic Vulnerabilities

Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3

Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer

Germline alterations of the RNASEL gene, a candidate HPC1 gene at 1q25, in patients and families with prostate cancer

Differential responses of stress genes to low dose-rate gamma irradiation

Molecular classification of familial non-BRCA1/BRCA2 breast cancer

Toward precision medicine in glioblastoma: the promise and the challenges

Molecular determinants of human uveal melanoma invasion and metastasis

Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease

Effects of RNase L mutations associated with prostate cancer on apoptosis induced by 2',5'-oligoadenylates

Gene expression signature of benign prostatic hyperplasia revealed by cDNA microarray analysis

Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma

Inherited genetic variant predisposes to aggressive but not indolent prostate cancer

Toward a drug development path that targets metastatic progression in osteosarcoma.

Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma

Stress-specific signatures: expression profiling of p53 wild-type and -null human cells

Advancing a clinically relevant perspective of the clonal nature of cancer

A cryptic BAP1 splice mutation in a family with uveal and cutaneous melanoma, and paraganglioma

Synthetic lethal RNAi screening identifies sensitizing targets for gemcitabine therapy in pancreatic cancer

Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type.

p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas

Genome-wide scan for prostate cancer susceptibility genes using families from the University of Michigan prostate cancer genetics project finds evidence for linkage on chromosome 17 near BRCA1.

Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenib

A genome scan for eye color in 502 twin families: most variation is due to a QTL on chromosome 15q.

The interaction of four genes in the inflammation pathway significantly predicts prostate cancer risk

A recurrent germline BAP1 mutation and extension of the BAP1 tumor predisposition spectrum to include basal cell carcinoma

Localization of a novel melanoma susceptibility locus to 1p22

Perspectives from man's best friend: National Academy of Medicine's Workshop on Comparative Oncology.

Inference from Clustering with Application to Gene-Expression Microarrays

Gene-expression profiling in human cutaneous melanoma

Adrenocortical carcinoma survival rates correlated to genomic copy number variants

Genome‐wide scan for prostate cancer susceptibility genes in the Johns Hopkins hereditary prostate cancer families

Functional evidence implicating S100P in prostate cancer progression

A Genome-wide Association Study Reveals that Variants within the HLA Region Are Associated with Risk for Nonobstructive Azoospermia

Generation and analysis of melanoma SAGE libraries: SAGE advice on the melanoma transcriptome