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List of works by L. Mario Amzel

6. Structure Determination of Biological Macromolecules using X-Ray Diffraction Analysis

scholarly article published 1982

A UDP-X Diphosphatase from Streptococcus pneumoniae Hydrolyzes Precursors of Peptidoglycan Biosynthesis

scientific article

A compact beta model of huntingtin toxicity

scientific article

A frequent kinase domain mutation that changes the interaction between PI3K  and the membrane

scientific article

A molecular-mechanics study of the conformation of the interchain disulfide of human immunoglobulin G4 (IgG4).

scientific article published on October 1988

A novel fucose recognition fold involved in innate immunity

scientific article

A redox regulatory system critical for mycobacterial survival in macrophages and biofilm development

scientific article published on 17 April 2015

A structural and thermodynamic escape mechanism from a drug resistant mutation of the HIV-1 protease

scientific article published in May 2004

ATP synthases--structure of the F1-moiety and its relationship to function and mechanism

scientific article published on August 1988

Activation of PI3Kα by physiological effectors and by oncogenic mutations: structural and dynamic effects

scientific article

Amidation of Bioactive Peptides: The Structure of the Lyase Domain of the Amidating Enzyme

scientific article

Amidation of bioactive peptides: the structure of peptidylglycine alpha-hydroxylating monooxygenase

scientific article

Asn441 plays a key role in folding and function of the Na+/I- symporter (NIS).

scientific article published on 06 May 2013

Beyond non-integer Hill coefficients: A novel approach to analyzing binding data, applied to Na+-driven transporters

scientific article

Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer

scientific article

C-terminal recognition by 14-3-3 proteins for surface expression of membrane receptors

scientific article published on 24 August 2005

Calculation of entropy changes in biological processes: folding, binding, and oligomerization

scientific article published in January 2000

Calmodulin and Ca(2+) control of voltage gated Na(+) channels

scientific article published on 28 July 2015

Capitalizing on tumor genotyping: towards the design of mutation specific inhibitors of phosphoinsitide-3-kinase

scientific article published on 28 October 2010

Chapter 15 The mediator of thyroidal iodide accumulation: The sodium/iodide symporter

Characterization of a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1 by biochemical, X-ray crystallographic, and mass spectrometric approaches

scientific article

Cloning and characterization of the gene encoding ATP-dependent phospho-enol-pyruvate carboxykinase in Trypanosoma cruzi: comparison of primary and predicted secondary structure with host GTP-dependent enzyme

scientific article published in December 1993

Compensating enthalpic and entropic changes hinder binding affinity optimization

scientific article

Coordination of peroxide to the CuM center of peptidylglycine α-hydroxylating monooxygenase (PHM): structural and computational study

scientific article

Correctly folded proteins make twice as many hydrophobic contacts

scientific article published on 01 January 1987

Crystal and Molecular Structure of a 6-Methyluracil Photodimer

scientific article published on 01 August 1972

Crystal and molecular structure of 2,5-dimethyl-3,4-diacetylfuran

Crystal and molecular structure of 2,5-dimethyl-3,4-diacetylpyrrole

Crystal structure of human quinone reductase type 2, a metalloflavoprotein

scientific article

Crystal structure of trans-dithiocyanatotetrakis-(NN′-diethylthiourea)-nickel(II)

scholarly article by L. M. Amzel et al published 1969 in Journal of the Chemical Society. A, Inorganic, physical, theoretical

Crystallization and preliminary X-ray diffraction studies of an anti-4-hydroxy-3-nitrophenylacetic acid monoclonal antibody Fab fragment complexed with immunizing and heteroclitic haptens

scientific article

Crystallization of F1 ATPase from rat liver mitochondria

scientific article

Design, Synthesis, Calorimetry, and Crystallographic Analysis of 2-Alkylaminoethyl-1,1-bisphosphonates as Inhibitors of Trypanosoma cruzi Farnesyl Diphosphate Synthase

scientific article

Development of Broad-Spectrum Halomethyl Ketone Inhibitors Against Coronavirus Main Protease 3CLpro

scientific article

Differential Reactivity between Two Copper Sites in Peptidylglycine α-Hydroxylating Monooxygenase

scientific article

Dioxygen binds end-on to mononuclear copper in a precatalytic enzyme complex

scientific article

Direct activation of Epac by sulfonylurea is isoform selective

scientific article published on February 2011

Disaccharide Binding to Galectin-1: Free Energy Calculations and Molecular Recognition Mechanism ⬇️

scientific article published on May 4, 2011

Do antiidiotypic antibodies mimic antigen?

scientific article

Effects of copper occupancy on the conformational landscape of peptidylglycine α-hydroxylating monooxygenase

Electrostatic guidance of glycosyl cation migration along the reaction coordinate of uracil DNA glycosylase

scientific article

Entropy in biological binding processes: estimation of translational entropy loss

scientific article published in January 1994

Enzymatic capture of an extrahelical thymine in the search for uracil in DNA

scientific article

Estimation of changes in side chain configurational entropy in binding and folding: general methods and application to helix formation

scientific article published in September 1994

Estimation of free-energy differences from computed work distributions: an application of Jarzynski's equality

scientific article published on 30 August 2012

F-type ATPases. Introduction

scientific article published on October 1992

F-type ATPases: are nucleotide domains in adenylate kinase appropriate models for nucleotide domains in ATP synthase/ATPase complexes?

scientific article

Flash-freezing causes a stress-induced modulation in a crystal structure of soybean lipoxygenase l3.

scientific article published in September 1996

Formycin triphosphate-terbium complex: a novel spectroscopic probe for phosphoryl transfer enzymes

scientific article published in December 1987

Glutamatergic regulation of serine racemase via reversal of PIP2 inhibition

scholarly article

Helix propensities calculations for amino acids in alanine based peptides using Jarzynski's equality

scientific article published in April 2010

How Much Binding Affinity Can be Gained by Filling a Cavity?

scientific article

Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization

scientific article published on 8 August 2002

Hydrogen bonding at a conserved threonine in lentivirus capsid is required for virus replication

scientific article

Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels

scientific article published on 6 October 2011

Identification of Bdellovibrio bacteriovorus HD100 Bd0714 as a Nudix dGTPase

scientific article published on 17 October 2008

Impact of linker strain and flexibility in the design of a fragment-based inhibitor

scientific article

Interactions of the products, 8-oxo-dGMP, dGMP, and pyrophosphate with the MutT nucleoside triphosphate pyrophosphohydrolase.

scientific article

Kinetic and mutational studies of the adenosine diphosphate ribose hydrolase from Mycobacterium tuberculosis

scientific article

Kinetic and structural analyses reveal residues in phosphoinositide 3-kinase α that are critical for catalysis and substrate recognition

scientific article

Letter: Crystallographic study of an esteroproteolytic enzyme

scientific article published in November 1973

Light adaptation through phosphoinositide-regulated translocation of Drosophila visual arrestin

scientific article published in July 2003

Loss of translational entropy in molecular associations

scientific article

Making the Right Moves

scientific article published on 01 August 2007

Mechanism of NAD(P)H:Quinone reductase: Ab initio studies of reduced flavin

article

Mechanism of NAD(P)H:quinone reductase: Ab initio studies of reduced flavin

scientific article

Mechanism of anion selectivity and stoichiometry of the Na+/I- symporter (NIS).

scientific article

Mechanism of the Escherichia coli ADP-ribose pyrophosphatase, a Nudix hydrolase

scientific article

Mechanism of titin unfolding by force: insight from quasi-equilibrium molecular dynamics calculations

scientific article published on 21 April 2006

Mimicking damaged DNA with a small molecule inhibitor of human UNG2.

scientific article

Modeling of nucleotide binding domains of ABC transporter proteins based on a F1-ATPase/recA topology: structural model of the nucleotide binding domains of the cystic fibrosis transmembrane conductance regulator (CFTR)

scientific article published on 01 October 1997

Modeling the variable region of immunoglobulins

article published in 1992

Modulation of MICAL Monooxygenase Activity by its Calponin Homology Domain: Structural and Mechanistic Insights.

scientific article published on 3 March 2016

Molecular basis of the catalytic differences among DT-diaphorase of human, rat, and mouse

scientific article published in January 1997

Mutation of Asn28 Disrupts the Dimerization and Enzymatic Activity of SARS 3CL pro

scientific article

Mutational, structural, and kinetic evidence for a dissociative mechanism in the GDP-mannose mannosyl hydrolase reaction

scientific article published in June 2005

Mutations in HOXD13 underlie syndactyly type V and a novel brachydactyly-syndactyly syndrome

scientific article

NHE3 activity is dependent on direct phosphoinositide binding at the N terminus of its intracellular cytosolic region.

scientific article

Na(+)/I(-) symporter activity requires a small and uncharged amino acid residue at position 395

scientific journal article

Na+ coordination at the Na2 site of the Na+/I- symporter

scientific article published on 25 August 2016

New insights into copper monooxygenases and peptide amidation: structure, mechanism and function

scientific article (publication date: August 2000)

Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation

scientific journal article

Notes on the mechanism of ATP synthesis

scientific article published on 01 October 2000

Novel Insights into the Chemical Mechanism of ATP Synthase

scientific article published in Journal of Biological Chemistry

On the molecular basis of the recognition of angiotensin II (AII). NMR structure of AII in solution compared with the X-ray structure of AII bound to the mAb Fab131.

scientific article

Oncogenic mutations weaken the interactions that stabilize the p110α-p85α heterodimer in phosphatidylinositol 3-kinase α.

scientific article

Phosphorylation-mediated PTEN conformational closure and deactivation revealed with protein semisynthesis

scientific article published on 09 July 2013

Physiological sodium concentrations enhance the iodide affinity of the Na+/I- symporter

scientific article

Polyglutamine fibrillogenesis: the pathway unfolds

scholarly article

Preliminary X-ray diffraction analysis of HhaII endonuclease-DNA cocrystals.

scientific article

Proton ATPase of rat liver mitochondria: A rapid procedure for purification of a stable, reconstitutively active F1 preparation using a modified chloroform method

scientific article published on 01 August 1984

Pyridinylpyrimidines selectively inhibit human methionine aminopeptidase-1

scientific article

Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1 in Cells

scientific article

Quaternary structure of ATP synthases: symmetry and asymmetry in the F1 moiety

scientific article published on October 1992

Recognition in cell adhesion. A comparative study of the conformations of RGD-containing peptides by Monte Carlo and NMR methods.

scientific article published on December 1989

Regulation of the NaV1.5 cytoplasmic domain by calmodulin

scientific article

Relation between positional specificity and chirality in mammalian lipoxygenases.

scientific article published on March 1998

Role of Entropy in Increased Rates of Intramolecular Reactions

article published in 2003

Role of Fluctuations in Quinone Reductase Hydride Transfer: a Combined Quantum Mechanics and Molecular Dynamics Study

article

Role of the outer pore domain in transient receptor potential vanilloid 1 dynamic permeability to large cations

scientific article

Sodium/Iodide Symporter Mutant V270E Causes Stunted Growth but No Cognitive Deficiency

scientific article

Somatic mutations in PI3Kalpha: structural basis for enzyme activation and drug design

scientific article

Structural Insights into Maize Viviparous14, a Key Enzyme in the Biosynthesis of the Phytohormone Abscisic Acid

scientific article

Structural analysis of affinity maturation: the three-dimensional structures of complexes of an anti-nitrophenol antibody

scientific article

Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus

scientific article published on 2 November 2015

Structural and functional diversity of the lectin repertoire in teleost fish: relevance to innate and adaptive immunity

scientific article

Structural and thermodynamic basis of the inhibition ofLeishmania majorfarnesyl diphosphate synthase by nitrogen-containing bisphosphonates

scientific article

Structural and thermodynamic insights into the recognition of native proteins by anti-peptide antibodies

scientific article published on 06 March 2013

Structural basis for the association of heavy and light chains and the relation of subgroups to the conformation of the active site of immunoglobulins

article

Structural basis of nSH2 regulation and lipid binding in PI3Kα.

scientific article

Structural comparisons of class I phosphoinositide 3-kinases

scientific article published on September 2008

Structural energetics of peptide recognition: Angiotensin II/antibody binding

scholarly article by Kenneth P. Murphy published in February 1993

Structural studies of the Nudix GDP-mannose hydrolase from E. coli reveals a new motif for mannose recognition

scientific article

Structure and Biological Function of the RNA Pyrophosphohydrolase BdRppH from Bdellovibrio bacteriovorus

scientific article

Structure and Specificity of a Binary Tandem Domain F-Lectin from Striped Bass (Morone saxatilis)

scientific article

Structure and activity of the axon guidance protein MICAL

scientific journal article

Structure and function of the E. coli dihydroneopterin triphosphate pyrophosphatase: a Nudix enzyme involved in folate biosynthesis

scientific article

Structure and mechanism of GDP-mannose glycosyl hydrolase, a Nudix enzyme that cleaves at carbon instead of phosphorus

scientific article

Structure and mechanism of MT-ADPRase, a nudix hydrolase from Mycobacterium tuberculosis

scientific article

Structure and mechanism of NAD[P]H:quinone acceptor oxidoreductases (NQO).

scientific article published on January 2004

Structure and mechanism of lipoxygenases.

scientific article published on November 1997

Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: implications for drug design

scientific article

Structure of F1-ATPase

scientific article published on August 1981

Structure of Fab New at 6 Å Resolution

scientific article published on 01 February 1972

Structure of a Coenzyme A Pyrophosphatase from Deinococcus radiodurans: a Member of the Nudix Family

scientific article

Structure, function, and mechanism of cytosolic quinone reductases

scientific article published on January 2008

Structure-Based Development of Anticancer Drugs

article

Structure-based drug design

scientific article published on 01 August 1998

Structures and mechanisms of Nudix hydrolases.

scientific article

Structures of mammalian cytosolic quinone reductases.

scientific article

Studies on the three-dimensional structure of immunoglobulins

Substrate-mediated electron transfer in peptidylglycine alpha-hydroxylating monooxygenase

scientific article

THE THREE-DIMENSIONAL STRUCTURE OF F1ATPases

scientific article published on 01 January 1982

Targeting the Cell Wall of Mycobacterium tuberculosis: Structure and Mechanism of L,D-Transpeptidase 2

scientific article

The 2.8-Å structure of rat liver F 1 -ATPase: Configuration of a critical intermediate in ATP synthesis/hydrolysis ⬇️

scientific article published on September 15, 1998

The Catalytic Mechanism of Peptidylglycine α-Hydroxylating Monooxygenase Investigated by Computer Simulation

scientific article published on 01 October 2006

The Hypoxic Regulator of Sterol Synthesis Nro1 Is a Nuclear Import Adaptor

scientific article

The Na+/I symporter (NIS) mediates electroneutral active transport of the environmental pollutant perchlorate

scholarly article

The Nudix Hydrolase CDP-Chase, a CDP-Choline Pyrophosphatase, Is an Asymmetric Dimer with Two Distinct Enzymatic Activities

scientific article

The X-Ray Structure and Biophysical Studies of a 15-Lipoxygenase

scientific article published on 01 November 1994

The catalytic copper of peptidylglycine alpha-hydroxylating monooxygenase also plays a critical structural role

scientific article

The structure of ADP-ribose pyrophosphatase reveals the structural basis for the versatility of the Nudix family

scientific article

The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations

scientific article

The three dimensional structure of a combining region-ligand complex of immunoglobulin NEW at 3.5-A resolution

scientific article published on April 1974

The three-dimensional structure of rat liver mitochodria F1-ATPase: X-ray diffraction studies

scientific article published on 01 August 1994

The three-dimensional structure of the fab' fragment of a human myeloma immunoglobulin at 2.0-angstrom resolution

scientific article

Thermodynamic calculations in biological systems

scientific article

Thermodynamics of bovine spleen galectin-1 binding to disaccharides: correlation with structure and its effect on oligomerization at the denaturation temperature

scientific article

Three dimensional structure of the pFc' fragment of guinea pig IgG1.

scientific article published in November 1979

Three-dimensional structure of the Fab' fragment of a human immunoglobulin at 2,8-A resolution

scientific article

True identity of a diffraction pattern attributed to valyl tRNA

scientific article published in Nature

Understanding ATP synthesis: structure and mechanism of the F1-ATPase (Review)

scientific article

Unique Thermodynamic Response of Tipranavir to Human Immunodeficiency Virus Type 1 Protease Drug Resistance Mutations

scientific article

X-ray, NMR, and mutational studies of the catalytic cycle of the GDP-mannose mannosyl hydrolase reaction

scientific article

α-Helix peptides designed from EBV-gH protein display higher antigenicity and induction of monocyte apoptosis than the native peptide.

scientific article

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