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List of works by Kenneth W. Kinzler

14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage

scientific article (publication date: 7 October 1999)

14-3-3sigma is a p53-regulated inhibitor of G2/M progression

scientific article

A Naturally Occurring hPMS2 Mutation Can Confer a Dominant Negative Mutator Phenotype ⬇️

scientific article published on March 1, 1998

A Robust Approach to Enhance Tumor-selective Accumulation of Nanoparticles ⬇️

scientific article published on January 1, 2011

A bacterial protein enhances the release and efficacy of liposomal cancer drugs

scientific article published on November 2006

A combination of molecular markers and clinical features improve the classification of pancreatic cysts

scientific article

A diaCEST MRI approach for monitoring liposomal accumulation in tumors

scientific article published on 15 February 2014

A frequent kinase domain mutation that changes the interaction between PI3K  and the membrane

scientific article

A gene for neurofibromatosis 2

scientific article published in Nature

A model for p53-induced apoptosis ⬇️

scientific article published on September 18, 1997

A molecular genetic linkage map of mouse chromosome 18 reveals extensive linkage conservation with human chromosomes 5 and 18

scientific article published on 01 August 1992

A multidimensional analysis of genes mutated in breast and colorectal cancers

scientific article

A multimodality test to guide the management of patients with a pancreatic cyst

scientific article published on 01 July 2019

A nanoparticle formulation that selectively transfects metastatic tumors in mice ⬇️

scientific article published on August 19, 2013

A novel approach for selecting combination clinical markers of pathology applied to a large retrospective cohort of surgically resected pancreatic cysts

scientific article published on 21 June 2016

A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53

scientific article

A phosphatase associated with metastasis of colorectal cancer

scientific article (publication date: 9 November 2001)

A protocol for rapid generation of recombinant adenoviruses using the AdEasy system

scientific article published on January 2007

A public database for gene expression in human cancers

scientific article

A simplified system for generating recombinant adenoviruses

scientific article

A transforming growth factor beta receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability

article

APC binds to the novel protein EB1 ⬇️

scientific article published on July 15, 1995

APC gene mutations and extraintestinal phenotype of familial adenomatous polyposis

scientific article published on April 1997

APC gene mutations in the mutation cluster region are rare in esophageal cancers.

scientific article published in December 1994

APC mutations in colorectal tumors with mismatch repair deficiency

scientific article published on August 1996

APC mutations occur early during colorectal tumorigenesis

scientific article published on September 17, 1992

ATM mutations in patients with hereditary pancreatic cancer

scientific article published on 29 December 2011

Absence of secretory phospholipase A2 gene alterations in human colorectal cancer ⬇️

scientific article published on November 15, 1995

Accumulation of driver and passenger mutations during tumor progression

scientific article

Achilles' heel of cancer?

scientific article published in Nature

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

scientific article

Allele separation facilitates interpretation of potential splicing alterations and genomic rearrangements

scientific article published on 01 August 2002

Allelic Variation in Human Gene Expression

scientific article published in Science

Allelic loss of chromosome 18q and prognosis in colorectal cancer

scientific article published on 01 July 1994

Allelotype of pancreatic adenocarcinoma

scientific article published on 01 May 1994

Alpha-1 adrenergic receptor antagonists for preventing acute respiratory distress syndrome and death from cytokine storm syndrome

scientific article published on 21 April 2020

Altered telomeres in tumors with ATRX and DAXX mutations

scientific article

Amplification of a gene encoding a p53-associated protein in human sarcomas

scientific article

Amplification of cyclin genes in colorectal carcinomas

scientific article published on 01 May 1993

Amplification units containing human N-myc and c-myc genes

scientific article published on February 1986

An analysis of genetic heterogeneity in untreated cancers

scientific article published on 27 August 2019

An engineered antibody fragment targeting mutant β-catenin via major histocompatibility complex I neoantigen presentation

scientific article published on 05 November 2019

An integrated genomic analysis of human glioblastoma multiforme

scientific article

An interview with Bert Vogelstein and Kenneth Kinzler

scientific article published in January 2015

Analysing uncharted transcriptomes with SAGE.

scientific article

Analysis of human transcriptomes.

scientific article published in December 1999

Analysis of masked mutations in familial adenomatous polyposis

scientific article published on March 1999

Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients

article

Analysis of mutations in DNA isolated from plasma and stool of colorectal cancer patients

scientific article published on 15 May 2008

Analysis of the 5' region of PMS2 reveals heterogeneous transcripts and a novel overlapping gene

scientific article

Annotated normal CT data of the abdomen for deep learning: Challenges and strategies for implementation

scientific article published on 26 July 2019

Apoptosis and APC in colorectal tumorigenesis

scientific article published on July 1996

Application of Deep Learning to Pancreatic Cancer Detection: Lessons Learned From Our Initial Experience

scientific article published on 01 September 2019

Applications of liquid biopsies for cancer

scientific article published on 01 August 2019

Aristolochic Acid in the Etiology of Renal Cell Carcinoma

scientific article published on 23 August 2016

Assessing aneuploidy with repetitive element sequencing

scientific article published on 19 February 2020

Assessing tumors in living animals through measurement of urinary beta-human chorionic gonadotropin

scientific article published on 01 June 2000

Assignment of the human p27Kip1 gene to 12p13 and its analysis in leukemias

scientific article published on 01 March 1995

Association between wild type and mutant APC gene products.

scientific article

Association of the APC tumor suppressor protein with catenins

scientific article (publication date: 10 December 1993)

Association of the autoimmune disease scleroderma with an immunologic response to cancer

scientific article published on 5 December 2013

BEAMing up for detection and quantification of rare sequence variants

scientific article published in February 2006

BEAMing: single-molecule PCR on microparticles in water-in-oil emulsions

scientific article

Bacteriolytic therapy can generate a potent immune response against experimental tumors

scholarly article

Bisulfite-converted duplexes for the strand-specific detection and quantification of rare mutations

scientific article

Breast cancer. What's mice got to do with it?

scientific article published on 01 August 1996

CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling

scientific article published on September 1999

Cancer genes and the pathways they control

scientific article

Cancer genome landscapes

scientific article

Cancer risk associated with germline DNA mismatch repair gene mutations

article

Cancer therapy meets p53

scientific article published on 01 July 1994

Cancer, crash sites, and the new genetics of neoplasia

scientific article published on 01 January 1999

Cancer-Associated Mutations in Endometriosis without Cancer.

scientific article published on May 2017

Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations

scientific article published on 04 August 2009

Cancer-susceptibility genes. Gatekeepers and caretakers

scientific article (publication date: 24 April 1997)

Carcinogen-specific induction of genetic instability.

scholarly article

Carcinogens leave fingerprints ⬇️

scientific article published on January 16, 1992

Cell surface tumor endothelial markers are conserved in mice and humans

scientific article (publication date: 15 September 2001)

Cell-cycle arrest versus cell death in cancer therapy ⬇️

scientific article published on 01 September 1997

Characterization of Human FAST-1, a TGFβ and Activin Signal Transducer ⬇️

scientific article published on July 1, 1998

Characterization of MAD2B and other mitotic spindle checkpoint genes

scientific article

Characterization of the yeast transcriptome

scientific article

Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers

scientific article

Circulating Tumor DNA Analyses as Markers of Recurrence Risk and Benefit of Adjuvant Therapy for Stage III Colon Cancer

scientific article published on 17 October 2019

Circulating mutant DNA to assess tumor dynamics

scientific article

Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer

scientific article

Circulating tumor DNA as a potential marker of adjuvant chemotherapy benefit following surgery for localized pancreatic cancer

scientific article published on 01 September 2019

Circulating tumor DNA as an early marker of therapeutic response in patients with metastatic colorectal cancer

scientific article published on 7 April 2015

Clinical, genomic, and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke

scientific article

Clinicopathological correlates of activating GNAS mutations in intraductal papillary mucinous neoplasm (IPMN) of the pancreas

scientific article published on 12 July 2013

Clostridium novyi-NT can cause regression of orthotopically implanted glioblastomas in rats

scientific article published on March 2015

Colorectal Cancer and the Intersection between Basic and Clinical Research ⬇️

scientific article published on January 1, 1994

Colorectal cancer: mutations in a signalling pathway

scientific article published in August 2005

Combination bacteriolytic therapy for the treatment of experimental tumors ⬇️

scientific article published on November 27, 2001

Combinatorial chemoprevention of intestinal neoplasia

scientific article published on 01 September 2000

Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers

scientific article published on 5 September 2017

Common occurrence of APC and K-ras gene mutations in the spectrum of colitis-associated neoplasias

scientific article published on 01 February 1995

Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma

scientific article

Comparative lesion sequencing provides insights into tumor evolution

scholarly article

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

scientific article

Contribution of bone marrow–derived endothelial cells to human tumor vasculature

Conversion of diploidy to haploidy

scientific article

Converting cancer genes into killer genes

scientific article published on April 1996

Cooperative effects of genes controlling the G(2)/M checkpoint

scientific article published in July 2000

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

scientific article

Correction to: persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1

article

Correction: Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy

article

Counting alleles reveals a connection between chromosome 18q loss and vascular invasion

scientific article published on January 2001

Counting alleles to predict recurrence of early-stage colorectal cancers

scientific article published on January 2002

CpG methylation is maintained in human cancer cells lacking DNMT1.

scientific article

DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors

scientific article

DEC1 is a downstream target of TGF-beta with sequence-specific transcriptional repressor activities

scientific article

DETECTION OF CIRCULATING TUMOR DNA IN EARLY AND LATE STAGE HUMAN MALIGNANCIES.

scientific article published in July 2014

DNA methylation and genetic instability in colorectal cancer cells

scientific article

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

scientific article (publication date: 4 April 2002)

Definition of a consensus binding site for p53

scientific article (publication date: April 1992)

Definition of the binding mode of a new class of phosphoinositide 3-kinase α-selective inhibitors using in vitro mutagenesis of non-conserved amino acids and kinetic analysis

scientific article

Deletion of p16 and p15 genes in brain tumors

scientific article (publication date: 15 December 1994)

Deregulation of energy metabolism promotes antifibrotic effects in human hepatic stellate cells and prevents liver fibrosis in a mouse model

scientific article published on 22 October 2015

Design and analysis issues in genome-wide somatic mutation studies of cancer

scientific article published on 23 August 2008

Detecting colorectal cancer in stool with the use of multiple genetic targets

scientific article published on June 2001

Detection and localization of surgically resectable cancers with a multi-analyte blood test.

scientific article published on 18 January 2018

Detection and quantification of mutations in the plasma of patients with colorectal tumors

scientific article

Detection and quantification of rare mutations with massively parallel sequencing ⬇️

scientific article published on May 17, 2011

Detection of APC mutations in fecal DNA from patients with colorectal tumors

scientific article published on January 2002

Detection of TERT promoter mutations in primary adenocarcinoma of the urinary bladder

scientific article published on 10 March 2016

Detection of aneuploidy in patients with cancer through amplification of long interspersed nucleotide elements (LINEs).

scientific article published on 5 February 2018

Detection of chromosomal alterations in the circulation of cancer patients with whole-genome sequencing

scientific article

Detection of circulating tumor DNA in early- and late-stage human malignancies

scientific article (publication date: 19 February 2014)

Detection of proximal colorectal cancers through analysis of faecal DNA

scientific article published on 01 February 2002

Detection of somatic TP53 mutations in tampons of patients with high-grade serous ovarian cancer

scientific article

Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas

scientific article

Detection of tumor DNA at the margins of colorectal cancer liver metastasis

scientific article published on 29 April 2011

Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord

scientific article

Development of personalized tumor biomarkers using massively parallel sequencing

scientific article

Diagnostic potential of tumor DNA from ovarian cyst fluid

scientific article published on 15 July 2016

Differentiating autoimmune pancreatitis from pancreatic ductal adenocarcinoma with CT radiomics features

scientific article published on 08 April 2020

Digital PCR

scientific article

Digital karyotyping

scientific article

Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients

scientific article

Direct Detection and Quantification of Neoantigens

scientific article published on 16 September 2019

Discodermolide analogues as the chemical component of combination bacteriolytic therapy

scientific article published in August 2005

Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome.

scientific article

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

scientific article

Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer ⬇️

scientific article published on February 1, 1992

Dissecting isoform selectivity of PI3K inhibitors: the role of non-conserved residues in the catalytic pocket

scientific article published on September 2008

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

scientific article

ET-58THE GENETICALLY ENGINEERED CLOSTRIDIUM NOVYI-NT IS EFFICACIOUS IN THE TREATMENT OF INTRACRANIAL GLIOBLASTOMAS.

scientific article published in November 2014

Early alteration of cell-cycle-regulated gene expression in colorectal neoplasia

scientific article published on August 1996

EcoRI polymorphism within the GLI gene (chromosome 12q13.3-14.1).

scientific article published on May 1990

Enrichment and Expansion with Nanoscale Artificial Antigen Presenting Cells for Adoptive Immunotherapy

scientific article published on 14 July 2015

Epitope landscape in breast and colorectal cancer

scientific article published in February 2008

Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells

Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells

scientific article

Erratum to "Annotated normal CT data of the abdomen for deep learning: Challenges and strategies for implementation" [Diagn. Interv. Imaging. 101 (2020) 35-44]

scientific article published on 20 May 2020

Evaluating the evaluation of cancer driver genes

scientific article

Evaluation of Clostridium novyi-NT spores in dogs with naturally occurring tumors

scientific article

Evaluation of DNA from the Papanicolaou test to detect ovarian and endometrial cancers

scientific article

Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers

scientific article published on 01 July 1996

Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers.

scientific article published in March 2018

Evaluation of the FHIT gene in colorectal cancers

scientific article published on 01 July 1996

Evidence for rearrangement, amplification, and expression of c-myc in a human glioblastoma

scientific article published on January 1986

Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis

scientific article published on 01 February 2001

Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

scientific article

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

scientific article (publication date: 26 August 2011)

Exomic analysis of myxoid liposarcomas, synovial sarcomas, and osteosarcomas

scientific article

Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene

scientific article

Exomic sequencing of four rare central nervous system tumor types

scientific article published on April 2013

Exomic sequencing of medullary thyroid cancer reveals dominant and mutually exclusive oncogenic mutations in RET and RAS.

scientific article published on 21 December 2012

Expression of the APC tumor suppressor protein in oligodendroglia

Expression of the APC tumor suppressor protein in oligodendroglia.

scientific article

Expression of the human mismatch repair gene hMSH2 in normal and neoplastic tissues

scientific article published on 01 January 1996

FAST-SeqS: A Simple and Efficient Method for the Detection of Aneuploidy by Massively Parallel Sequencing ⬇️

scientific article published on July 18, 2012

Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses

scientific article

Familial and sporadic pancreatic cancer share the same molecular pathogenesis

scientific article

Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC ⬇️

scientific article published on September 1, 1997

Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention

scientific article published on 28 April 2020

Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells

scientific article

Founding mutations and Alu-mediated recombination in hereditary colon cancer

scientific article

Frequency of Smad gene mutations in human cancers.

scientific article published in July 1997

Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas

scientific article

Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma

scientific article

GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity

scientific article

GNAS codon 201 mutations are uncommon in intraductal papillary neoplasms of the bile duct

scientific article

GNAS sequencing identifies IPMN-specific mutations in a subgroup of diminutive pancreatic cysts referred to as "incipient IPMNs".

scientific article published on March 2014

Gene amplification in cancer: a molecular cytogenetic approach

scientific article published in January 1986

Gene expression analysis goes digital

scientific article published in August 2007

Gene expression profiles in normal and cancer cells

scientific article (publication date: 23 May 1997)

Generation of MANAbodies specific to HLA-restricted epitopes encoded by somatically mutated genes

scientific article published on 27 July 2015

Genes expressed in human tumor endothelium

scientific article

Genetic determinants of p53-induced apoptosis and growth arrest

scientific article published on August 1996

Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells

scholarly article

Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation

scientific article

Genetic instabilities in human cancers

scientific article (publication date: 17 December 1998)

Genetic instability and darwinian selection in tumours

Genetic instability and darwinian selection in tumours

scientific article

Genetic instability in colorectal cancers

scientific article (publication date: 10 April 1997)

Genetic instability occurs in the majority of young patients with colorectal cancer

scientific article published on April 1995

Genetic landscape of extreme responders with anaplastic oligodendroglioma

scientific article

Genetic mutations associated with cigarette smoking in pancreatic cancer

scientific article

Genetic progression and the waiting time to cancer

scientific article

Genetically defined subsets of human pancreatic cancer show unique in vitro chemosensitivity

scientific article

Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing

scientific article

Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma

scientific article published in Nature Communications

Genomic landscape and evolutionary trajectories of ovarian cancer precursor lesions

scientific article published on 15 February 2019

Genomic organization of the human PMS2 gene family.

scientific article

Genotyping by mass spectrometric analysis of short DNA fragments

scientific article published on December 1998

Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells

scientific article

Going mad with Smads

scientific article

Has the breast cancer gene been found?

scientific article published on October 1994

Heteroplasmic mitochondrial DNA mutations in normal and tumour cells

scientific article

High frequency of mutations of the PIK3CA gene in human cancers

scientific article (publication date: 23 April 2004)

High prevalence of TERT promoter mutations in micropapillary urothelial carcinoma

scientific article

High prevalence of TERT promoter mutations in primary squamous cell carcinoma of the urinary bladder

scientific article

Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene

scientific article published in January 2003

Human Smad3 and Smad4 Are Sequence-Specific Transcription Activators ⬇️

scientific article published on March 1, 1998

Hyper-recombination and genetic instability in BLM-deficient epithelial cells

scientific article published on December 2003

Hypermutability and mismatch repair deficiency in RER+ tumor cells

scientific article published on December 1993

IDH1 and IDH2 mutations in gliomas

scientific article

Identification and classification of p53-regulated genes

scientific article published on December 1999

Identification of CDK4 as a target of c-MYC.

scholarly article

Identification of FAP locus genes from chromosome 5q21

scientific article

Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T

scientific article

Identification of a Gene Located at Chromosome 5q21 that Is Mutated in Colorectal Cancers ⬇️

scientific article published on March 15, 1991

Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R

scientific article

Identification of a chromosome 18q gene that is altered in colorectal cancers

scientific article

Identification of allosteric binding sites for PI3Kα oncogenic mutant specific inhibitor design

scientific article

Identification of an amplified, highly expressed gene in a human glioma

scientific article

Identification of c- MYC as a Target of the APC Pathway ⬇️

scientific article published on September 4, 1998

Identification of compounds that inhibit growth of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine-resistant cancer cells

scientific article published on June 2005

Identification of microbial DNA in human cancer

scientific article

Identification of p53 as a sequence-specific DNA-binding protein

scientific article

Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors

scientific article published on April 3, 1992

Identifying markers for pancreatic cancer by gene expression analysis ⬇️

scientific article published on 01 February 1998

IgH gene rearrangements as plasma biomarkers in Non- Hodgkin's lymphoma patients

scientific article

Imaging bacterial infections with radiolabeled 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodouracil

scientific article

Imaging of musculoskeletal bacterial infections by [124I]FIAU-PET/CT

scientific article

In situ hybridization localizes the human putative oncogene GLI to chromosome subbands 12q13.3-14.1.

scientific article published on 01 April 1989

In vivo cloning of PCR products in E. coli

scientific article published on November 1993

Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers

scholarly article

Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma

scientific article

Inactivation of both APC alleles in human and mouse tumors

scientific journal article

Inactivation of hCDC4 can cause chromosomal instability

scientific article published on March 2004

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

scientific article

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma ⬇️

scientific article (publication date: 9 June 1998)

Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification

scientific article

Insertion/deletion polymorphism and other restriction fragment length polymorphisms in the MCC gene ⬇️

scientific article published on January 1, 1992

Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers

scientific article

Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma

scientific article

Intraductal papillary mucinous neoplasm in a neonate with congenital hyperinsulinism and a de novo germline SKIL gene mutation

scientific article

Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses

scientific article

Knudson's hypothesis and the TP53 revolution ⬇️

scientific article published on December 1, 2003

Landscaping the cancer terrain

scientific article

Large-scale identification of novel transcripts in the human genome

scientific article published on 31 January 2007

Lavage of the Uterine Cavity for Molecular Detection of Müllerian Duct Carcinomas: A Proof-of-Concept Study

scientific article

Less death in the dying

scientific article published on 01 April 1997

Lessons from hereditary colorectal cancer

scientific article (publication date: 18 October 1996)

Life (and death) in a malignant tumour

scientific article published in Nature

Limited detection of IgH gene rearrangements in plasma of patients with primary central nervous system lymphoma ⬇️

scientific article published on July 5, 2013

Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer

scientific article published on 16 January 2017

Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway

scientific article

Low-grade serous carcinomas of the ovary contain very few point mutations

scientific article

Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) Diagnostics

MIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma

scientific article published on 01 July 2003

Mad-related genes in the human

scientific article

Mammalian cells resistant to tumor suppressor genes

scientific article published on August 1996

Mapping of multiple intestinal neoplasia (Min) to proximal chromosome 18 of the mouse.

scientific article

Mechanisms underlying losses of heterozygosity in human colorectal cancers

scholarly article

Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis ⬇️

scientific article published on January 20, 1998

Microbiota organization is a distinct feature of proximal colorectal cancers ⬇️

scientific article

Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer ⬇️

scientific article published on December 1, 1995

Minimal functional driver gene heterogeneity among untreated metastases

scientific article published in Science

Mismatch Repair Deficiency in Phenotypically Normal Human Cells ⬇️

scientific article published on May 5, 1995

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.

scientific article

Molecular cloning of the N-terminus of GTBP

scientific article

Molecular determinants of dysplasia in colorectal lesions.

scientific article published in November 1994

Molecular diagnosis of familial adenomatous polyposis.

scientific article

Molecular genetic profiles of colitis-associated neoplasms

scientific article published on 01 August 1994

Monoallelic mutation analysis (MAMA) for identifying germline mutations

scientific article

Multicolor in vitro translation

scientific article published on 10 August 2003

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

scientific article (publication date: May 1992)

Mutant PIK3CA promotes cell growth and invasion of human cancer cells

scientific article published on June 2005

Mutant p53 proteins bind DNA abnormally in vitro

scientific article published on 01 January 1991

Mutant proteins as cancer-specific biomarkers

scientific article

Mutation Screening of the TNFRSF11A Gene Encoding Receptor Activator of NFkB (RANK) in Familial and Sporadic Paget's Disease of Bone and Osteosarcoma

article

Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer ⬇️

scientific article published on March 15, 1998

Mutational analysis of the tyrosine kinome in colorectal cancers

scientific article (publication date: 9 May 2003)

Mutational analysis of the tyrosine phosphatome in colorectal cancers

scientific article

Mutational inactivation of transforming growth factor beta receptor type II in microsatellite stable colon cancers.

scientific article published in January 1999

Mutational signature of aristolochic acid exposure as revealed by whole-exome sequencing

scientific article

Mutations in CIC and FUBP1 contribute to human oligodendroglioma

scientific article (publication date: 9 September 2011)

Mutations of GTBP in genetically unstable cells

scientific article

Mutations of mitotic checkpoint genes in human cancers ⬇️

scientific article published on March 19, 1998

Mutations of the APC (adenomatous polyposis coli) gene in FAP (familial polyposis coli) patients and in sporadic colorectal tumors

scientific article published on 01 October 1992

Mutations of the adenomatous polyposis coli gene in familial polyposis coli patients and sporadic colorectal tumors

scientific article published on 01 January 1991

Myxoid liposarcoma with t(12;16) (q13;p11) contains site-specific differences in methylation patterns surrounding a zinc-finger gene mapped to the breakpoint region on chromosome 12.

scientific article published on December 1990

NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae

scientific article

Necessity Is the Mother of Invention: The Development of Digital Genomics

scientific article

Next-Generation Stool DNA Test Accurately Detects Colorectal Cancer and Large Adenomas ⬇️

scientific article published on November 4, 2011

Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy.

scientific article published on 20 March 2018

Noninvasive imaging of infection after treatment with tumor-homing bacteria using Chemical Exchange Saturation Transfer (CEST) MRI.

scientific article

ONCOGENESIS: Landscaping the Cancer Terrain

scientific article published in Science

Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer

scientific article published on 20 June 2016

Oncogenic forms of p53 inhibit p53-regulated gene expression

scientific article

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

scientific article (publication date: 29 April 1993)

Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria

scientific article

PAK1, a gene that can regulate p53 activity in yeast

scientific article

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

scientific article

PI3Kα Inhibitors That Inhibit Metastasis ⬇️

scientific article published on September 1, 2010

PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs

scientific article

PRINT: A Protein Bioconjugation Method with Exquisite N-terminal Specificity

scientific article

PRL-3 expression in metastatic cancers

scientific article (publication date: 15 November 2003)

PUMA induces the rapid apoptosis of colorectal cancer cells

scientific article

PUMA mediates the apoptotic response to p53 in colorectal cancer cells

scientific article

Paradoxical inhibition of solid tumor cell growth by bcl2

scientific article published on 01 July 1994

Pathogenesis of adenocarcinoma in Peutz-Jeghers syndrome.

scientific article

Patient-oriented gene set analysis for cancer mutation data

scientific article

Performance of novel non-invasive urine assay UroSEEK in cohorts of equivocal urine cytology

scientific article published on 03 September 2019

Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1

article

Pharmacologic and toxicologic evaluation of C. novyi-NT spores

scientific article published on 14 September 2005

Phosphorylation of beta-catenin at S33, S37, or T41 can occur in the absence of phosphorylation at T45 in colon cancer cells ⬇️

scientific article published on 01 September 2003

Polymerase delta variants in RER colorectal tumours

scientific article

Precancerous neoplastic cells can move through the pancreatic ductal system

scientific article published in Nature

Prediction of germline mutations and cancer risk in the Lynch syndrome

scientific article published on September 2006

Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia

scientific article published on 5 January 2012

Presymptomatic direct detection of adenomatous polyposis coli (APC) gene mutations in familial adenomatous polyposis.

scientific article

Prevalence of somatic alterations in the colorectal cancer cell genome

scientific article

Preventing cytokine storm syndrome in COVID-19 using α-1 adrenergic receptor antagonists

scientific article published on 30 April 2020

Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome

scientific article

Prognostic Potential of Circulating Tumor DNA Measurement in Postoperative Surveillance of Nonmetastatic Colorectal Cancer

scientific article published on 09 May 2019

Progression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer ⬇️

scientific article published on March 1, 1992

RAF/RAS oncogenes and mismatch-repair status

scientific article published in Nature

Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development

scientific article

Relationship between gene amplification and chromosomal deviations in malignant human gliomas

scientific article published in November 1987

Remote loading of preencapsulated drugs into stealth liposomes

scientific article published on 28 January 2014

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

scientific article (publication date: 20 November 1998)

Response to Comments on "The Consensus Coding Sequences of Human Breast and Colorectal Cancers"

scientific article published in Science

Response to Comments on "The Predictive Capacity of Personal Genome Sequencing"

Revisiting the tumorigenesis timeline with a data-driven generative model

scientific article published on 27 December 2019

Role of BAX in the apoptotic response to anticancer agents

scientific article

SAM 1.1 and JOSH 4.4: two RFLPs within the human DCC gene

scientific article published on 01 August 1992

SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells

scholarly article

SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer

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Scrambled exons

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Secreted and cell surface genes expressed in benign and malignant colorectal tumors

scientific article published on 01 October 2001

Securin is required for chromosomal stability in human cells

scientific article (publication date: 18 May 2001)

Selected reaction monitoring approach for validating peptide biomarkers

scientific article published on 4 December 2017

Sensitive digital quantification of DNA methylation in clinical samples

scientific article

Sequence analysis of 515 kinase genes in chronic lymphocytic leukemia

scientific article

Sequence-specific transcriptional activation is essential for growth suppression by p53.

scientific article

Serial Assessment of Human Tumor Burdens in Mice by the Analysis of Circulating DNA

article

Serial analysis of gene expression

scientific article (publication date: 20 October 1995)

Serial circulating tumour DNA analysis during multimodality treatment of locally advanced rectal cancer: a prospective biomarker study.

scientific article

Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers

scientific article published on April 2004

Short mononucleotide repeat sequence variability in mismatch repair-deficient cancers

scientific article published on 01 May 2001

Small changes in expression affect predisposition to tumorigenesis ⬇️

scientific article published on December 17, 2001

Somatic mutations in CCK2R alter receptor activity that promote oncogenic phenotypes

scientific article

Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types

scientific article

Somatic mutations in the transcriptional corepressor gene BCORL1 in adult acute myelogenous leukemia ⬇️

scientific article published on October 11, 2011

Somatic mutations of EGFR in colorectal cancers and glioblastomas

scientific article published in December 2004

Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers

scientific article

Somatic mutations of SUZ12 in malignant peripheral nerve sheath tumors

scientific article published on 12 October 2014

Somatic mutations of the mitochondrial genome in human colorectal tumours ⬇️

scientific article published on November 1, 1998

Spectrum of genetic mutations in de novo PUNLMP of the urinary bladder

scientific article

Spore coat architecture of Clostridium novyi NT spores

scientific article

Structural basis of nSH2 regulation and lipid binding in PI3Kα.

scientific article

Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens

scientific article published on 06 September 2021

Sulindac suppresses tumorigenesis in the Min mouse

scientific article

Suppression of carcinogenesis in the intestines of min mice by the soybean-derived Bowman-Birk inhibitor

scientific article published on 01 February 1996

Synthesis and Pharmacological Evaluation of 4-Iminothiazolidinones for Inhibition of PI3 Kinase

scientific article published on January 2012

Synthesis and evaluation of aminophosphinic acid derivatives as inhibitors of renal dipeptidase

scientific article

TCR β chain-directed bispecific antibodies for the treatment of T cell cancers

scientific article published on 01 March 2021

TEM8 interacts with the cleaved C5 domain of collagen alpha 3(VI).

scientific article published in February 2004

TERT PROMOTER MUTATIONS OCCUR FREQUENTLY IN GLIOMAS AND A SUBSET OF TUMORS DERIVED FROM CELLS WITH LOW RATES OF SELF-RENEWAL.

scientific article published in July 2014

TERT promoter mutations occur early in urothelial neoplasia and are biomarkers of early disease and disease recurrence in urine

scientific article published on 11 October 2013

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

scientific article published on 25 March 2013

Targeted deletion of Smad4 shows it is required for transforming growth factor β and activin signaling in colorectal cancer cells ⬇️

scientific article published on March 3, 1998

Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation

scientific article

Targeted inactivation of p53 in human cells does not result in aneuploidy

scientific article published on 01 February 2002

Targeted sequencing of plasmacytoid urothelial carcinoma reveals frequent TERT promoter mutations

scientific article published on 14 November 2018

Targeting the catecholamine-cytokine axis to prevent SARS-CoV-2 cytokine storm syndrome

scientific article published on 08 April 2020

Targeting vascular and avascular compartments of tumors with C. novyi-NT and anti-microtubule agents

scientific article

Tech.sight. Genetic testing--present and future

scientific article

The DCC gene product in cellular differentiation and colorectal tumorigenesis

scientific article (publication date: 15 May 1994)

The GLI gene encodes a nuclear protein which binds specific sequences in the human genome

scientific article

The GLI gene is a member of the Kruppel family of zinc finger proteins

scientific article

The GLI-Kruppel family of human genes

scientific article

The Path to Cancer --Three Strikes and You're Out

scientific article published on 01 November 2015

The antisense transcriptomes of human cells

scientific article

The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression.

scientific article

The colorectal cancer gene hunt: current findings

scientific article

The colorectal microRNAome

scientific article

The consensus coding sequences of human breast and colorectal cancers

scientific article

The early detection of pancreatic cancer: what will it take to diagnose and treat curable pancreatic neoplasia?

scientific article

The gene for the APC-binding protein beta-catenin (CTNNB1) maps to chromosome 3p22, a region frequently altered in human malignancies

scientific article published on 01 January 1995

The genetic landscape of the childhood cancer medulloblastoma

scientific article

The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT.

scientific article published on 19 November 2006

The genomic landscapes of human breast and colorectal cancers

scientific article

The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers

scientific article (publication date: 13 June 2012)

The multistep nature of cancer

scientific article

The potential role of circulating tumor DNA (ctDNA) in the further investigation of colorectal cancer patients with nonspecific findings on standard investigations

scientific article published on 24 January 2019

The predictive capacity of personal genome sequencing

scientific article published on 02 April 2012

The role of companion diagnostics in the development and use of mutation-targeted cancer therapies

scientific article published on August 2006

The role of hPMS1 and hPMS2 in predisposing to colorectal cancer ⬇️

scientific article published on 01 November 2001

The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations

scientific article

The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints

scientific article

The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints

The zinc finger protein GLI transforms primary cells in cooperation with adenovirus E1A ⬇️

scientific article published on March 1, 1991

Thiazolidinedione-based PI3Kα inhibitors: an analysis of biochemical and virtual screening methods

scientific article

Three classes of genes mutated in colorectal cancers with chromosomal instability

scientific article published in May 2004

Three dinucleotide repeat polymorphisms proximal to the D2S123 locus

scientific article published on 01 November 1994

Through the glass lightly

Top-down morphogenesis of colorectal tumors

scholarly article

Transforming growth factor-beta-induced growth inhibition in a Smad4 mutant colon adenoma cell line

scientific article

Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations

scientific article

Tumor endothelial marker 1 (Tem1) functions in the growth and progression of abdominal tumors

scholarly article

Tumour suppression: disruption of HAUSP gene stabilizes p53

scientific article

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

scientific article published in Nature

Use of isogenic human cancer cells for high-throughput screening and drug discovery

scientific article

Using the transcriptome to annotate the genome

scientific article

Utility of CT Radiomics Features in Differentiation of Pancreatic Ductal Adenocarcinoma From Normal Pancreatic Tissue

scientific article published on 23 April 2019

Very Long-term Survival Following Resection for Pancreatic Cancer Is Not Explained by Commonly Mutated Genes: Results of Whole-Exome Sequencing Analysis

scientific article

WAF1, a potential mediator of p53 tumor suppression

scientific article (publication date: 19 November 1993)

Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer

scientific article published on 9 December 2015

Whole genome PCR: application to the identification of sequences bound by gene regulatory proteins

scientific article

Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers

scientific article published on 04 January 2016

Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma

scientific article

Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways

scientific article published on 8 December 2011

Whole-exome sequencing of pancreatic neoplasms with acinar differentiation

scientific article

Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution

scientific article

Wild-type but not mutant APC associates with the microtubule cytoskeleton.

scientific article published on July 1994

Winning the War: Science Parkour ⬇️

scientific article published on March 28, 2012

X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells

scientific article published on May 2004

X-rays strike p53 again

scientific article published in Nature

p21 is necessary for the p53-mediated G1 arrest in human cancer cells ⬇️

scientific article published on November 15, 1995

p53 Mutation and MDM2 amplification in human soft tissue sarcomas

scientific article published on 01 May 1993

p53 function and dysfunction

scientific article published on August 21, 1992

p53 tagged sites from human genomic DNA.

scientific article published on September 1994

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

scientific article published on 01 April 1995

p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest

scientific article

β-Catenin Mutations: Insights into the APC Pathway and the Power of Genetics

scientific article

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