List of works - Dinshaw J. Patel

Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF

scientific article (publication date: 6 July 2006)

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

scientific article

Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense

scientific article (publication date: December 2006)

Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain

scientific article

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

scientific article

Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

scientific article

Structure of the guide-strand-containing argonaute silencing complex

scientific article

Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes

scientific article

Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger

scientific article

Recognition of small interfering RNA by a viral suppressor of RNA silencing

scientific article

Dicer recognizes the 5' end of RNA for efficient and accurate processing

scientific article

DNA methylation pathways and their crosstalk with histone methylation

scientific article (publication date: September 2015)

WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity

scientific article

TRIM24 links a non-canonical histone signature to breast cancer

scientific article

Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution

scientific article

Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA

scientific article

Structure of the Human Telomere in K + Solution: A Stable Basket-Type G-Quadruplex with Only Two G-Tetrad Layers

scientific article

Structure of DNMT1-DNA Complex Reveals a Role for Autoinhibition in Maintenance DNA Methylation

scientific article

Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants

scientific article

Structure of an Unprecedented G-Quadruplex Scaffold in the Human c-kit Promoter

scientific article

Ribozymes, riboswitches and beyond: regulation of gene expression without proteins

scientific article

A Poised Chromatin Platform for TGF-β Access to Master Regulators

scientific article

Structure of yeast Argonaute with guide RNA

scientific article published on June 20, 2012

The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier–Gorlin syndrome

scientific article

Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I

scientific article

Structural insights into amino acid binding and gene control by a lysine riboswitch

scientific article

Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA Methylation

scientific article published on February 10, 2012

DAXX envelops a histone H3.3-H4 dimer for H3.3-specific recognition

scientific article

Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1

scientific article

The evolutionary journey of Argonaute proteins

scientific article

ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome

scientific article

Two-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: distinct topologies, thermodynamic properties, and folding/unfolding kinetics

scientific article

Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger

scientific article

PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression

scientific article published on July 22, 2011

An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting

scientific article

SRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation

scientific article

Uridylation by TUT4 and TUT7 marks mRNA for degradation

scientific article

Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases

scientific article published on May 22, 2014

Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1

scientific article

Coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch

scientific article

Phosphorylation of human Argonaute proteins affects small RNA binding.

scientific article

Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion

scientific article

Structural basis for recognition and sequestration of UUU(OH) 3' temini of nascent RNA polymerase III transcripts by La, a rheumatic disease autoantigen

scientific article

Structural Insights into Ligand Recognition by a Sensing Domain of the Cooperative Glycine Riboswitch

scientific article

Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids

scientific article

Metabolite recognition principles and molecular mechanisms underlying riboswitch function

scientific article (publication date: 2012)

Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter

scientific article

Structural basis for glycosphingolipid transfer specificity

scientific article

A stable transcription factor complex nucleated by oligomeric AML1–ETO controls leukaemogenesis

scientific article published on June 30, 2013

Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage

scientific article

List of works by Dinshaw J. Patel

Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense

Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

Structure of the guide-strand-containing argonaute silencing complex

Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes

Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger

Recognition of small interfering RNA by a viral suppressor of RNA silencing

Dicer recognizes the 5' end of RNA for efficient and accurate processing

DNA methylation pathways and their crosstalk with histone methylation

WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity

TRIM24 links a non-canonical histone signature to breast cancer

Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution

Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA

Structure of the Human Telomere in K + Solution: A Stable Basket-Type G-Quadruplex with Only Two G-Tetrad Layers

Structure of DNMT1-DNA Complex Reveals a Role for Autoinhibition in Maintenance DNA Methylation

Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants

Structure of an Unprecedented G-Quadruplex Scaffold in the Human c-kit Promoter

Ribozymes, riboswitches and beyond: regulation of gene expression without proteins

A Poised Chromatin Platform for TGF-β Access to Master Regulators

Structure of yeast Argonaute with guide RNA

The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier–Gorlin syndrome

Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I

Structural insights into amino acid binding and gene control by a lysine riboswitch

Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA Methylation

DAXX envelops a histone H3.3-H4 dimer for H3.3-specific recognition

Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1

The evolutionary journey of Argonaute proteins

ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome

Two-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: distinct topologies, thermodynamic properties, and folding/unfolding kinetics

Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger

PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression

An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting

SRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation

Uridylation by TUT4 and TUT7 marks mRNA for degradation

Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases

Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1

Coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch

Phosphorylation of human Argonaute proteins affects small RNA binding.

Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion

Structural basis for recognition and sequestration of UUU(OH) 3' temini of nascent RNA polymerase III transcripts by La, a rheumatic disease autoantigen

Structural Insights into Ligand Recognition by a Sensing Domain of the Cooperative Glycine Riboswitch

Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids

Metabolite recognition principles and molecular mechanisms underlying riboswitch function

Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter

Structural basis for glycosphingolipid transfer specificity

A stable transcription factor complex nucleated by oligomeric AML1–ETO controls leukaemogenesis

Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage