List of works by Andrzej Joachimiak

"System 48" high-throughput cloning and protein expression analysis.

scientific article published on January 2009

1.6 A crystal structure of YteR protein from Bacillus subtilis, a predicted lyase.

scientific article

1.6 A crystal structure of a PA2721 protein from pseudomonas aeruginosa--a potential drug-resistance protein

scientific article published on June 2006

2'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography

scholarly article by Mateusz Wilamowski et al published 25 May 2021 in Proceedings of the National Academy of Sciences of the United States of America

3D domain swapping in the TIM barrel of the α subunit of Streptococcus pneumoniae tryptophan synthase

scientific article published on 31 January 2020

A 2.08 Å resolution structure of HLB5, a novel cellulase from the anaerobic gut bacterium Parabacteroides johnsonii DSM 18315

A 2.08 Å resolution structure of HLB5, a novel cellulase from the anaerobic gut bacterium Parabacteroides johnsonii DSM 18315

scientific article published on 18 February 2019

A conformational switch controls cell wall-remodelling enzymes required for bacterial cell division

scientific article

A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair

scientific article

A family of LIC vectors for high-throughput cloning and purification of proteins

scientific article published on January 2009

A family of metal-dependent phosphatases implicated in metabolite damage-control

scientific article

A microbial sensor for organophosphate hydrolysis exploiting an engineered specificity switch in a transcription factor

scientific article

A novel cofactor-binding mode in bacterial IMP dehydrogenases explains inhibitor selectivity

scientific article

A novel polyamine allosteric site of SpeG from Vibrio cholerae is revealed by its dodecameric structure

scientific journal article

A novel signal transduction protein: Combination of solute binding and tandem PAS-like sensor domains in one polypeptide chain

scientific article

A novel transcriptional regulator of L-arabinose utilization in human gut bacteria

scientific article

A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase.

scientific article published on 3 July 2017

A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus

scientific article

Activation of Inhibitors by Sortase Triggers Irreversible Modification of the Active Site

scientific article

Activity screening of environmental metagenomic libraries reveals novel carboxylesterase families

scientific article

Allosteric inhibitors of Mycobacterium tuberculosis tryptophan synthase

scientific article published on 20 January 2020

An expression vector tailored for large-scale, high-throughput purification of recombinant proteins

scientific article published on 30 January 2006

Analysis of periplasmic sensor domains fromAnaeromyxobacter dehalogenans2CP-C: Structure of one sensor domain from a histidine kinase and another from a chemotaxis protein

scientific article

Application of spermine-Sepharose column chromatography to the separation of plant-specific transfer ribonucleic acids and aminoacyl-tRNA synthetases

scientific article published on November 28, 1979

Aromatic claw: A new fold with high aromatic content that evades structural prediction

scientific article

Assisted assignment of ligands corresponding to unknown electron density

scientific article

Automation of protein purification for structural genomics

scientific article published on January 2004

Autotracing of Escherichia coli acetate CoA-transferase alpha-subunit structure using 3.4 A MAD and 1.9 A native data

December 2002 scientific article in Acta Crystallographica Section D: Biological Crystallography

B. subtilis ykuD protein at 2.0 A resolution: insights into the structure and function of a novel, ubiquitous family of bacterial enzymes

scientific article published in January 2006

Bacillus anthracis Inosine 5′-Monophosphate Dehydrogenase in Action: The First Bacterial Series of Structures of Phosphate Ion-, Substrate-, and Product-Bound Complexes

scientific article

Bifidobacterium longum subsp. infantis ATCC 15697  -Fucosidases Are Active on Fucosylated Human Milk Oligosaccharides

scientific article

Biochemical and Structural Characterization of a Novel Family of Cystathionine β-Synthase Domain Proteins Fused to a Zn Ribbon-Like Domain

scientific article

Biochemical and Structural Insights into Enzymatic Depolymerization of Polylactic Acid and Other Polyesters by Microbial Carboxylesterases.

scientific article

Biochemical and structural analysis of an Eis family aminoglycoside acetyltransferase from bacillus anthracis

scientific article

Chapter 3. High-throughput protein purification for x-ray crystallography and NMR.

scientific article

Characteristics and crystal structure of bacterial inosine-5'-monophosphate dehydrogenase

scientific article

Characterization and Crystal Structure of a Nonheme Diiron Monooxygenase Involved in Platensimycin and Platencin Biosynthesis

scientific article published on 23 July 2019

Characterization of Transport Proteins for Aromatic Compounds Derived from Lignin: Benzoate Derivative Binding Proteins

scientific article

Characterization of a Bacillus subtilis transporter for petrobactin, an anthrax stealth siderophore

scientific article

Characterization of member of DUF1888 protein family, self-cleaving and self-assembling endopeptidase

scientific article

ChemInform Abstract: Differential Signatures of Bacterial and Mammalian IMP Dehydrogenase Enzymes

Cleavable C-terminal His-tag vectors for structure determination.

scientific article

Co-occurrence of analogous enzymes determines evolution of a novel (βα)8-isomerase sub-family after non-conserved mutations in flexible loop.

scientific article published on 29 February 2016

Conformational cycle of the archaeosome, a TCP1-like chaperonin from Sulfolobus shibatae

scientific article published on 01 December 1995

Conservation of the structure and function of bacterial tryptophan synthases

scientific article published on 29 May 2019

Conservation of the structures of plant tRNAs and aminoacyl-tRNA synthetases

scientific article published on June 1, 1979

Conserved protein YecM fromEscherichia coli shows structural homology to metal-binding isomerases and oxygenases

scientific article (publication date: May 2003)

Conserved residue His-257 of Vibrio cholerae flavin transferase ApbE plays a critical role in substrate binding and catalysis

scientific article published on 26 July 2019

Contributions to the NIH-NIGMS Protein Structure Initiative from the PSI Production Centers.

scientific article

Convergent Evolution of the Barnase/EndoU/Colicin/RelE (BECR) Fold in Antibacterial tRNase Toxins

scientific article published on 09 September 2019

Conversion ofd‐ribulose 5‐phosphate toD‐xylulose 5‐phosphate: new insights from structural and biochemical studies on human RPE

scientific article published on October 5, 2010

Corrigendum to "A Novel Polyamine Allosteric Site of SpeG from Vibrio Cholerae is Revealed by its Dodecameric Structure" [J. Mol. Biol. 427 (6 Part B) (2015) 1316-1334]

scientific article published on 22 October 2019

Crystal Structure of Bacillus anthracis Transpeptidase Enzyme CapD

scientific article

Crystal Structure of Enterococcus faecalis SlyA-like Transcriptional Factor

scientific article (publication date: 30 May 2003)

Crystal Structure of Thermotoga maritima 0065, a Member of the IclR Transcriptional Factor Family

scientific article

Crystal Structure of Thioesterase SgcE10 Supporting Common Polyene Intermediates in 9- and 10-Membered Enediyne Core Biosynthesis

scientific article published on 30 August 2017

Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892

scientific article

Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus.

scientific article

Crystal packing modifies ligand binding affinity: The case of aldose reductase

scientific article

Crystal structure and putative function of small Toprim domain-containing protein from Bacillus stearothermophilus

scientific article

Crystal structure of Bacillus subtilis YckF: structural and functional evolution.

scientific article published on October 2004

Crystal structure of Bacillus subtilis YdaF protein: a putative ribosomal N-acetyltransferase.

scientific article published on December 2004

Crystal structure of Legionella pneumophila Lpp1115 / KaiB

Crystal structure of MboIIA methyltransferase

scientific article

Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2

scientific article published on 3 March 2020

Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2

scientific article published on 17 April 2020

Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor

scientific article

Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027

scientific article

Crystal structure of YfeU protein from Haemophilus influenzae: a predicted etherase involved in peptidoglycan recycling

scientific article published on 21 February 2009

Crystal structure of a novel shikimate dehydrogenase from Haemophilus influenzae.

scientific article published on 25 February 2005

Crystal structure of a predicted precorrin-8x methylmutase from Thermoplasma acidophilum

scientific article published on February 2005

Crystal structure of aminopeptidase N from human pathogen Neisseria meningitidis

scientific article

Crystal structure of an acetyltransferase protein fromVibrio choleraestrain N16961

scientific article

Crystal structure of fatty acid/phospholipid synthesis protein PlsX from Enterococcus faecalis

scientific article

Crystal structure of glutamine amidotransferase fromThermotoga maritima

scientific article

Crystal structure of human stem cell factor: implication for stem cell factor receptor dimerization and activation

scientific article published in July 2000

Crystal structure of hypothetical protein YfiH from Shigella flexneri at 2 A resolution

scientific article

Crystal structure of murine sCEACAM1a[1,4]: a coronavirus receptor in the CEA family

scientific article

Crystal structure of secretory protein Hcp3 from Pseudomonas aeruginosa

scientific article

Crystal structure of tabtoxin resistance protein complexed with acetyl coenzyme A reveals the mechanism for beta-lactam acetylation

scientific article

Crystal structure of the CorA Mg2+ transporter

scientific article

Crystal structure of the TSP-1 type 1 repeats

scientific article

Crystal structure of the dachshund homology domain of human SKI

scientific article

Crystal structure of the extracellular segment of integrin alpha Vbeta3

scientific article

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

scientific article

Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule

scientific article

Crystal structure of the human GGA1 GAT domain

scientific article (publication date: 3 June 2003)

Crystal structure of the hypothetical protein TA1238 from Thermoplasma acidophilum: a new type of helical super-bundle

scientific article published on January 2004

Crystal structure of the ligand-binding domain of a LysR-type transcriptional regulator: transcriptional activation via a rotary switch

scientific article published on 01 November 2018

Crystal structure of the novel PaiA N-acetyltransferase from Thermoplasma acidophilum involved in the negative control of sporulation and degradative enzyme production

scientific article

Crystal structure of the novel PaiB transcriptional regulator from Geobacillus stearothermophilus

scientific article

Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus

scientific article

Crystal structure of trp repressor/operator complex at atomic resolution

scientific article

Crystal structure ofBacillus subtilis ioli shows endonuclase IV fold with altered Zn binding

scientific article

Crystal structure ofEscherichia coli EC1530, a glyoxylate induced protein YgbM

scientific article

Crystal structures of SARS-CoV-2 ADP-ribose phosphatase (ADRP): from the apo form to ligand complexes

scientific article published on 15 May 2020

Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes

scientific article published on 17 July 2020

Crystal structures of delta1-pyrroline-5-carboxylate reductase from human pathogens Neisseria meningitides and Streptococcus pyogenes.

scientific article published on 02 September 2005

Crystal structures of the F and pSLT plasmid TraJ N-terminal regions reveal similar homodimeric PAS folds with functional interchangeability

scientific article

Crystal structures of the effector-binding domain of repressor Central glycolytic gene Regulator fromBacillus subtilisreveal ligand-induced structural changes upon binding of several glycolytic intermediates

scientific article

Crystallographic analysis of a novel complex of actinomycin D bound to the DNA decamer CGATCGATCG

scientific article

Deep trefoil knot implicated in RNA binding found in an archaebacterial protein

scientific article

Differential signatures of bacterial and mammalian IMP dehydrogenase enzymes

scientific article published on 01 July 1999

Directly photocrosslinked nucleotides joining transfer RNA to aminoacyl-tRNA synthetase in methionine and tyrosine systems

scientific article published on 01 January 1985

Distinct B cell subsets give rise to antigen-specific antibody responses against SARS-CoV-2

scientific article published on 25 September 2020

Erratum: Crystal structure of trp represser/operator complex at atomic resolution

scientific article published in Nature

EsxB, a secreted protein from Bacillus anthracis forms two distinct helical bundles

scientific article

Extracytoplasmic PAS-Like Domains Are Common in Signal Transduction Proteins

scientific article

Flexibility of the DNA-binding domains of trp repressor

scientific article

Fluorescence-based thermal shift data on multidrug regulator AcrR from Salmonella enterica subsp. entrica serovar Typhimurium str. LT2

scientific article

Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae: BIOCHEMICAL, STRUCTURAL, AND EVOLUTIONARY INSIGHTS.

scientific article published on 12 June 2015

Functional and Structural Analysis of the Siderophore Synthetase AsbB through Reconstitution of the Petrobactin Biosynthetic Pathway from Bacillus anthracis

scientific article

Functional and Structural Characterization of Four Glutaminases from Escherichia coli and Bacillus subtilis †

scientific article

Functional inferences from crystals of Escherichia coli trp repressor

scientific article published on October 25, 1983

Functional plasticity of antibacterial EndoU toxins

scientific article published on 12 August 2018

GH1-family 6-P-β-glucosidases from human microbiome lactic acid bacteria

scientific article

Gene selection and cloning approaches for co-expression and production of recombinant protein-protein complexes.

scientific article published on 15 December 2015

Harvesting the high-hanging fruit: the structure of the YdeN gene product from Bacillus subtilis at 1.8 angstroms resolution

scientific article

Heparin-induced cis- and trans-Dimerization Modes of the Thrombospondin-1 N-terminal Domain

scientific article

Hexahydrated magnesium ions bind in the deep major groove and at the outer mouth of A-form nucleic acid duplexes

scientific article

High-Resolution Structure of the Nitrile Reductase QueF Combined with Molecular Simulations Provide Insight into Enzyme Mechanism

scientific article published on September 25, 2010

High-throughput protein purification and quality assessment for crystallization

scientific article

Higher plant 5S rRNAs share common secondary and tertiary structure. A new three domains model

article

How Aromatic Compounds Block DNA Binding of HcaR Catabolite Regulator

scientific article published on 25 April 2016

Human Hsp70 molecular chaperone binds two calcium ions within the ATPase domain

scientific article

Identification of unknown protein function using metabolite cocktail screening

scientific article

Improved integration of single-cell transcriptome and surface protein expression by LinQ-View

scientific article published on 23 July 2021

In situ X-ray data collection and structure phasing of protein crystals at Structural Biology Center 19-ID.

scientific article

In situ proteolysis for protein crystallization and structure determination

scientific article

Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril.

scientific article

Insight into the sporulation phosphorelay: Crystal structure of the sensor domain ofBacillus subtilishistidine kinase, KinD

scientific article

Insights from the Structure of Mycobacterium tuberculosis Topoisomerase I with a Novel Protein Fold

scientific article published on 3 December 2015

Insights into PG-Binding, Conformational Change, and Dimerization of the OmpA C-terminal Domains from Salmonella enterica serovar Typhimurium and Borrelia burgdorferi

scientific article

Integrating Structure, Bioinformatics, and Enzymology to Discover Function: BioH, A NEW CARBOXYLESTERASE FROM ESCHERICHIA COLI

scientific article (publication date: 11 July 2003)

Interaction of J-Protein Co-Chaperone Jac1 with Fe–S Scaffold Isu Is Indispensable In Vivo and Conserved in Evolution

scientific article

Interaction of alkaloids with plant transfer ribonucleic acids. Effect of sparteine on lupin arginyl-tRNA formation

scientific article published on 01 October 1982

Interaction of antidiabetic α-glucosidase inhibitors and gut bacteria α-glucosidase

scientific article published on 10 July 2018

Investigating mycobacterial topoisomerase I mechanism from the analysis of metal and DNA substrate interactions at the active site

scientific article published on 01 August 2018

Large-scale evaluation of protein reductive methylation for improving protein crystallization

scientific article published on October 2008

Loop-to-helix transition in the structure of multidrug regulator AcrR at the entrance of the drug-binding cavity.

scientific article published on 18 January 2016

MAD data collection - current trends.

scientific article

Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet

scientific article

Meeting review: 2003 NIH Protein Structure Initiative Workshop in Protein Production and Crystallization for Structural and Functional Genomics.

scientific article

Methyltransferase That Modifies Guanine 966 of the 16 S rRNA: FUNCTIONAL IDENTIFICATION AND TERTIARY STRUCTURE

scientific article

Mitigation of X-ray damage in macromolecular crystallography by submicrometre line focusing

scientific article

Mitochondrial Hsp90 is a ligand-activated molecular chaperone coupling ATP binding to dimer closure through a coiled-coil intermediate.

scientific article published on 29 February 2016

Molecular evolution of plants as deduced from changes in free energy of 5S ribosomal RNAs

scientific article published on 01 August 1990

Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds

scientific article

N. meningitidis 1681 is a member of the FinO family of RNA chaperones

scientific article published on November 1, 2010

NDM-1, the ultimate promiscuous enzyme: substrate recognition and catalytic mechanism

scientific article

NMR structure of protein yqbG from Bacillus subtilis reveals a novel alpha-helical protein fold

scientific article published on 01 January 2006

Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme

scientific article published on 04 June 2018

New LIC vectors for production of proteins from genes containing rare codons

scientific article published on 22 September 2013

New aminopeptidase from "microbial dark matter" archaeon

scientific article

New sub-family of lysozyme-like proteins shows no catalytic activity: crystallographic and biochemical study of STM3605 protein from Salmonella Typhimurium

scientific article published on March 2013

New surface contacts formed upon reductive lysine methylation: improving the probability of protein crystallization

scientific article

Novel hexamerization motif is discovered in a conserved cytoplasmic protein from Salmonella typhimurium

scientific article

Novel  -glucosidase from human gut microbiome: substrate specificities and their switch

scientific article

Optimization of Benzoxazole-Based Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase

scientific article

Outcome of a workshop on applications of protein models in biomedical research

scientific article (publication date: 13 February 2009)

Outcome of a workshop on archiving structural models of biological macromolecules

scientific article

Outcome of the First wwPDB/CCDC/D3R Ligand Validation Workshop

scientific article

Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteria

scientific article

Protein production and purification

scientific article

Protein production for structural genomics using E. coli expression

scientific article

Protein surface analysis for function annotation in high-throughput structural genomics pipeline

scientific article

Purification and characterization of trp aporepressor

scientific article published on February 1, 1983

Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase

scientific article

Raf kinase inhibitory protein function is regulated via a flexible pocket and novel phosphorylation-dependent mechanism

scientific article published on 22 December 2008

Resistance to Enediyne Antitumor Antibiotics by Sequestration

scientific article published on 21 June 2018

Rigid monoclonal antibodies improve detection of SARS-CoV-2 nucleocapsid protein

scientific article published in January 2021

Roles of intramolecular and intermolecular interactions in functional regulation of the Hsp70 J-protein co-chaperone Sis1.

scientific article

Room-temperature X-ray crystallography reveals the oxidation and reactivity of cysteine residues in SARS-CoV-2 3CL Mpro: insights into enzyme mechanism and drug design

scientific article published on 21 September 2020

RsaM: a transcriptional regulator ofBurkholderiaspp. with novel fold

scientific article

SARS-CoV-2 infection severity is linked to superior humoral immunity against the spike

scientific article published on 13 September 2020

Salvage of failed protein targets by reductive alkylation

scientific article

Screening and characterization of novel polyesterases from environmental metagenomes with high hydrolytic activity against synthetic polyesters

article

Sensor domain of histidine kinase KinB of Pseudomonas: a helix-swapped dimer.

scientific article

Staphylococcus aureus IsdG and IsdI, heme-degrading enzymes with structural similarity to monooxygenases

scientific article

Streptococcus pneumonia YlxR at 1.35 A shows a putative new fold

scientific article

Streptococcus pneumoniaYlxR at 1.35 Å shows a putative new fold

article

Structural Basis and Catalytic Mechanism for the Dual Functional Endo-β-N-Acetylglucosaminidase A

scientific article

Structural Basis for Catalysis by the Mono- and Dimetalated Forms of the dapE-Encoded N-succinyl-l,l-Diaminopimelic Acid Desuccinylase

scientific article

Structural Characterization of CalS8, a TDP-α-D-Glucose Dehydrogenase Involved in Calicheamicin Aminodideoxypentose Biosynthesis

scientific article

Structural Evidence for a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism.

scientific article published on 22 December 2017

Structural Insight into the Mechanism of c-di-GMP Hydrolysis by EAL Domain Phosphodiesterases

scientific article

Structural Insights into the Free-Standing Condensation Enzyme SgcC5 Catalyzing Ester-Bond Formation in the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027.

scientific article published on 13 March 2018

Structural Studies of ROK Fructokinase YdhR from Bacillus subtilis: Insights into Substrate Binding and Fructose Specificity

scientific article

Structural analysis of free and liganded forms of the Fab fragment of a high-affinity anti-cocaine antibody, h2E2

scientific article published on 05 November 2019

Structural and Biochemical Characterization of the Type II Fructose-1,6-bisphosphatase GlpX from Escherichia coli

scientific article

Structural and Functional Analysis of Human HtrA3 Protease and Its Subdomains

scientific article

Structural and Functional Characterization of DUF1471 Domains of Salmonella Proteins SrfN, YdgH/SssB, and YahO

scientific article

Structural and Functional Characterization of Microcin C Resistance Peptidase MccF from Bacillus anthracis

scientific article

Structural and biochemical analysis of the metallo-β-lactamase L1 from emerging pathogen Stenotrophomonas maltophilia revealed the subtle but distinct di-metal scaffold for catalytic activity

scientific article published on 24 December 2019

Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases

scientific article published on 29 September 2015

Structural and functional analysis of AsbF: Origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis

scientific article

Structural and functional characterization of solute binding proteins for aromatic compounds derived from lignin:p-Coumaric acid and related aromatic acids

scientific article

Structural basis for dimerization of ICAM-1 on the cell surface

scientific article published in April 2004

Structural basis for suppression of hypernegative DNA supercoiling by E. coli topoisomerase I

scientific article

Structural basis for the inhibition of human 5,10-methenyltetrahydrofolate synthetase by N10-substituted folate analogues

scientific article

Structural basis of membrane targeting by the Phox homology domain of cytokine-independent survival kinase (CISK-PX).

scientific article published on 4 May 2004

Structural bioinformatics: from protein structure to function

Structural characterization and comparison of three acyl-carrier-protein synthases from pathogenic bacteria

scientific article

Structural characterization of AtmS13, a putative sugar aminotransferase involved in indolocarbazole AT2433 aminopentose biosynthesis

scientific article

Structural dynamics of a methionine γ-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate.

scientific article published on 29 April 2016

Structural genomics: keeping up with expanding knowledge of the protein universe

scientific article

Structural insight into acute intermittent porphyria

scientific article

Structural plasticity in the oestrogen receptor ligand-binding domain

scientific article

Structural plasticity of SARS-CoV-2 3CL Mpro active site cavity revealed by room temperature X-ray crystallography

scientific article published on 24 June 2020

Structure and Activity of the Metal-independent Fructose-1,6-bisphosphatase YK23 from Saccharomyces cerevisiae

scientific article

Structure and activity of the Pseudomonas aeruginosa hotdog-fold thioesterases PA5202 and PA2801

scientific article

Structure and electrostatic property of cytoplasmic domain of ZntB transporter

scientific article

Structure and function of Bacillus subtilis YphP, a prokaryotic disulfide isomerase with a CXC catalytic motif

scientific article

Structure and recognition of sheared tandem G x A base pairs associated with human centromere DNA sequence at atomic resolution

scientific article

Structure of 2-oxo-3-deoxygalactonate kinase fromKlebsiella pneumoniae

scientific article

Structure of Apo- and Monometalated Forms of NDM-1—A Highly Potent Carbapenem-Hydrolyzing Metallo-β-Lactamase

scientific article

Structure of Bacillus subtilis YXKO--a member of the UPF0031 family and a putative kinase

scientific article

Structure of Cryptosporidium IMP dehydrogenase bound to an inhibitor with in vivo antiparasitic activity

scientific article published on 21 April 2015

Structure of Escherichia coli ribose-5-phosphate isomerase: a ubiquitous enzyme of the pentose phosphate pathway and the Calvin cycle

scientific article

Structure of RapA, a Swi2/Snf2 Protein that Recycles RNA Polymerase During Transcription

scientific article

Structure of RsrI methyltransferase, a member of the N6-adenine beta class of DNA methyltransferases

scientific article

Structure of SAICAR synthase from Thermotoga maritima at 2.2 angstroms reveals an unusual covalent dimer.

scientific article

Structure of SO2946 orphan from Shewanella oneidensis shows “jelly-roll” fold with carbohydrate-binding module

scientific article

Structure of Surface Layer Homology (SLH) Domains from Bacillus anthracis Surface Array Protein

scientific article

Structure of Thermotoga maritima stationary phase survival protein SurE: a novel acid phosphatase

scientific article

Structure of YidB protein from Shigella flexneri shows a new fold with homeodomain motif

scientific article

Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA

scientific article

Structure of a cupin protein Plu4264 from Photorhabdus luminescens subsp. laumondii TTO1 at 1.35 Å resolution

scientific article

Structure of a new crystal form of human Hsp70 ATPase domain

scientific article

Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs

scientific article

Structure of an Amide Bond Forming F420:γγ-glutamyl Ligase from Archaeoglobus Fulgidus - A Member of a New Family of Non-ribosomal Peptide Synthases

scientific article

Structure of cyanase reveals that a novel dimeric and decameric arrangement of subunits is required for formation of the enzyme active site

scientific article

Structure of cyclin G-associated kinase (GAK) trapped in different conformations using nanobodies

scientific article

Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors

scientific article published on 6 August 2020

Structure of phage protein BC1872 from Bacillus cereus, a singleton with new fold.

scientific article published on July 2006

Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases

scientific article

Structure of the ent-Copalyl Diphosphate Synthase PtmT2 from Streptomyces platensis CB00739, a Bacterial Type II Diterpene Synthase.

scientific article

Structure of the influenza virus A H5N1 nucleoprotein: implications for RNA binding, oligomerization, and vaccine design

scientific article

Structure of the retinal determination protein Dachshund reveals a DNA binding motif

scientific article

Structure of transcription factor HetR required for heterocyst differentiation in cyanobacteria

scientific article

Structure- and function-based characterization of a new phosphoglycolate phosphatase from Thermoplasma acidophilum

scientific article

Structures of complexes comprised of Fischerella transcription factor HetR with Anabaena DNA targets

scientific article

Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism

scientific article

Structures of open (R) and close (T) states of prephenate dehydratase (PDT)—Implication of allosteric regulation by l-phenylalanine

scientific article

Structures of sortase B from Staphylococcus aureus and Bacillus anthracis reveal catalytic amino acid triad in the active site

scientific article

Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation

scientific article

Substrate-Induced Allosteric Change in the Quaternary Structure of the Spermidine N-Acetyltransferase SpeG.

scientific article

Synthesis, in vitro evaluation and cocrystal structure of 4-oxo-[1]benzopyrano[4,3-c]pyrazole Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase (CpIMPDH) inhibitors

scientific article

Taking MAD to the extreme: ultrafast protein structure determination

scientific article

Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016).

scientific article published on 28 September 2017

Target highlights in CASP13: Experimental target structures through the eyes of their authors

scientific article published on 09 September 2019

Target selection and determination of function in structural genomics

scientific article

Tertiary structure and computer modeling of plant 5S ribosomal RNA

article

The 1.38 Å crystal structure of DmsD protein fromSalmonella typhimurium, a proofreading chaperone on the Tat pathway

scientific article

The 2.2 A resolution structure of RpiB/AlsB from Escherichia coli illustrates a new approach to the ribose-5-phosphate isomerase reaction

scientific article

The CDI toxin of Yersinia kristensenii is a novel bacterial member of the RNase A superfamily

scientific article

The CRISPR-associated Cas4 protein Pcal_0546 from Pyrobaculum calidifontis contains a [2Fe-2S] cluster: crystal structure and nuclease activity

scientific article

The Mannitol Operon Repressor MtlR Belongs to a New Class of Transcription Regulators in Bacteria

scientific article

The MotA transcription factor from bacteriophage T4 contains a novel DNA-binding domain: the 'double wing' motif

scientific article

The Structural Biology Center 19ID undulator beamline: facility specifications and protein crystallographic results.

scientific article published on 22 December 2005

The atomic resolution structure of human aldose reductase reveals that rearrangement of a bound ligand allows the opening of the safety-belt loop

scientific article

The crystal structure of Aq_328 from the hyperthermophilic bacteria Aquifex aeolicus shows an ancestral histone fold.

scientific article published on January 2006

The crystal structure of BlmI as a model for nonribosomal peptide synthetase peptidyl carrier proteins

scientific article

The crystal structure of Escherichia coli MoaB suggests a probable role in molybdenum cofactor synthesis

scientific article

The crystal structure of a T cell receptor in complex with peptide and MHC class II

scientific article

The crystal structure of a TL/CD8alphaalpha complex at 2.1 A resolution: implications for modulation of T cell activation and memory

scientific article (publication date: February 2003)

The crystal structure of a novel SAM-dependent methyltransferase PH1915 from Pyrococcus horikoshii

scientific article published on 31 October 2005

The crystal structure of nsp10-nsp16 heterodimer from SARS-CoV-2 in complex with S-adenosylmethionine

scientific article published on 20 April 2020

The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor

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The crystal structure of the bacterial chaperonin GroEL at 2.8 A

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The crystal structure of the effector-binding domain of the trehalose repressor TreR from Bacillus subtilis 168 reveals a unique quarternary assembly

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The crystal structure of the reduced, Zn2+-bound form of the B. subtilis Hsp33 chaperone and its implications for the activation mechanism

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The crystal structure of the signature domain of cartilage oligomeric matrix protein: implications for collagen, glycosaminoglycan and integrin binding

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The crystal structures of the α-subunit of the α(2)β (2) tetrameric Glycyl-tRNA synthetase

scientific article published on 06 October 2012

The dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase from Haemophilus influenzae contains two active-site histidine residues

scientific article published on 19 August 2008

The dimerization domain in DapE enzymes is required for catalysis

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The membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus binds the dipeptide GlyMet via side chain interactions

scientific article published on December 2004

The structural basis for methylmalonic aciduria. The crystal structure of archaeal ATP:cobalamin adenosyltransferase

scientific article published on 25 March 2004

The structure and ligand binding properties of the B. subtilis YkoF gene product, a member of a novel family of thiamin/HMP-binding proteins

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The structure of DinB from Geobacillus stearothermophilus: a representative of a unique four-helix-bundle superfamily

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The structure of pyogenecin immunity protein, a novel bacteriocin-like immunity protein from Streptococcus pyogenes

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The structure of theyrdCgene product fromEscherichia colireveals a new fold and suggests a role in RNA binding

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The structures of the thrombospondin-1 N-terminal domain and its complex with a synthetic pentameric heparin

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The three-dimensional structure of trp repressor.

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Time-controlled microfluidic seeding in nL-volume droplets to separate nucleation and growth stages of protein crystallization

scientific article published on December 2006

Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2

scientific article published on 26 June 2020

Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2

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To automate or not to automate: this is the question

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Toroidal Structure and DNA Cleavage by the CRISPR-Associated [4Fe-4S] Cluster Containing Cas4 Nuclease SSO0001 from Sulfolobus solfataricus

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Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication

scientific article published on 3 August 2021

Triclinic lysozyme at 0.65 A resolution

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Unusual binding mode of the 2S4R stereoisomer of the potent aldose reductase cyclic imide inhibitor fidarestat (2S4S) in the 15 K crystal structure of the ternary complex refined at 0.78 A resolution: implications for the inhibition mechanism

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Using surface-bound rubidium ions for protein phasing

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Virtual high-throughput ligand screening

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X-Ray crystal structure of GarR—tartronate semialdehyde reductase from Salmonella typhimurium

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X-ray crystal structure of CutA from Thermotoga maritima at 1.4 Å resolution

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X-ray crystal structures of the pheromone-binding domains of two quorum-hindered transcription factors, YenR of Yersinia enterocolitica and CepR2 of Burkholderia cenocepacia.

scientific article published on 14 June 2017

X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution

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X-ray-induced deterioration of disulfide bridges at atomic resolution

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X-ray-radiation-induced cooperative atomic movements in protein

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