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List of works by Scott W. Lowe

A Gain-of-Function p53-Mutant Oncogene Promotes Cell Fate Plasticity and Myeloid Leukemia through the Pluripotency Factor FOXH1

scientific article published on 08 May 2019

A Targetable Myeloid Inflammatory State Governs Disease Recurrence in Clear-Cell Renal Cell Carcinoma

scientific article published in 2022

A gene–environment-induced epigenetic program initiates tumorigenesis

scientific article published on 03 February 2021

A rectal cancer organoid platform to study individual responses to chemoradiation

scientific article published on 07 October 2019

An epigenetic mechanism underlying chromosome 17p deletion-driven tumorigenesis

scientific article published on 25 September 2020

Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia

scientific article published on January 2012

Arid1a restrains Kras-dependent changes in acinar cell identity.

scientific article published on 17 July 2018

Author Correction: Senolytic CAR T cells reverse senescence-associated pathologies

scientific article published in 2024

Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants

scientific article published in 2022

Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis

scientific article published on 11 May 2023

Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors

scientific article published on 11 September 2020

Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks

scientific article published on 08 October 2020

Global regulation of the histone mark H3K36me2 underlies epithelial plasticity and metastatic progression

scientific article published on 18 March 2020

Ketohexokinase-mediated fructose metabolism is lost in hepatocellular carcinoma and can be leveraged for metabolic imaging

scientific article published on 06 April 2022

L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer

scientific article published on 13 January 2020

Leukemia cell of origin influences apoptotic priming and sensitivity to LSD1 inhibition

scientific article published on 30 June 2020

NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination

scientific article published on 01 December 2018

Optimized base editors enable efficient editing in cells, organoids and mice

scientific article published on 03 July 2018

Phase and context shape the function of composite oncogenic mutations

scientific article published on 27 May 2020

Preclinical murine platform to evaluate therapeutic countermeasures against radiation-induced gastrointestinal syndrome

scientific article published on 24 September 2019

Senescence induction dictates response to chemo- and immunotherapy in preclinical models of ovarian cancer

scientific article published in 2022

Senolytic CAR T cells reverse senescence-associated pathologies

scientific article published on 17 June 2020

Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease

scientific article published in 2024

Somatic tissue engineering in mouse models reveals an actionable role for WNT pathway alterations in prostate cancer metastasis

scientific article published on 06 May 2020

The Canonical Wnt Pathway Drives Macropinocytosis in Cancer

scientific article published on 05 June 2018

Variability of inducible expression across the hematopoietic system of tetracycline transactivator transgenic mice.

scientific article

α-Ketoglutarate links p53 to cell fate during tumour suppression

scientific article published on 18 September 2019

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