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List of works by Bengt Fadeel

"But many that are first shall be last; and the last shall be first"

scientific article published on 01 May 2009

A Biodegradable Multifunctional Graphene Oxide Platform for Targeted Cancer Therapy

scientific article published on 01 August 2019

A Blueprint for the Synthesis and Characterisation of Thin Graphene Oxide with Controlled Lateral Dimensions for Biomedicine

A journey of hope: lessons learned from studies on rare diseases and orphan drugs

scientific article published on July 2006

A role for oxidative stress in apoptosis: oxidation and externalization of phosphatidylserine is required for macrophage clearance of cells undergoing Fas-mediated apoptosis

scientific article published on July 2002

AIF and Scythe (Bat3) Regulate Phosphatidylserine Exposure and Macrophage Clearance of Cells Undergoing Fas (APO-1)-Mediated Apoptosis

scientific article published on October 15, 2012

Aberrant mitochondrial iron distribution and maturation arrest characterize early erythroid precursors in low-risk myelodysplastic syndromes

scientific article published on 8 March 2005

Ablation of the pro-apoptotic protein Bax protects mice from glucocorticoid-induced bone growth impairment

scientific article published on 19 March 2012

Adsorption of surfactant lipids by single-walled carbon nanotubes in mouse lung upon pharyngeal aspiration

journal article published in 2012

Advanced tools for the safety assessment of nanomaterials

scholarly article by Bengt Fadeel et al published July 2018 in Nature Nanotechnology

Adverse effects of engineered nanomaterials

book published in 2012

Adverse effects of engineered nanomaterials: exposure, toxicology, and impact on human health, second edition

book published in 2017

All along the watchtower: on the regulation of apoptosis regulators.

scientific article

An endothelial laminin isoform, laminin 8 (alpha4beta1gamma1), is secreted by blood neutrophils, promotes neutrophil migration and extravasation, and protects neutrophils from apoptosis.

scientific article

Antiapoptotic role of growth factors in the myelodysplastic syndromes: concordance between in vitro and in vivo observations

scientific article

Apoptosis and macrophage clearance of neutrophils: regulation by reactive oxygen species

scientific article

Apoptosis in human disease: a new skin for the old ceremony?

scientific article

Apoptosis in refractory anaemia with ringed sideroblasts is initiated at the stem cell level and associated with increased activation of caspases

scientific article published in March 2001

Apoptosis modulation of Epstein-Barr virus-encoded latent membrane protein 1 in the epithelial cell line HeLa is stimulus-dependent

scientific article published on December 2002

Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease

scientific article

Apoptotic interactions of cytochrome c: redox flirting with anionic phospholipids within and outside of mitochondria

journal article published in 2006

Appetizing rancidity of apoptotic cells for macrophages: oxidation, externalization, and recognition of phosphatidylserine

journal article published in 2003

Applying quantitative structure-activity relationship approaches to nanotoxicology: current status and future potential.

scientific article published on 16 November 2012

Assignment of the gene locus for severe congenital neutropenia to chromosome 1q22 in the original Kostmann family from Northern Sweden

scientific article published on 20 December 2006

Babies born without safety NET

scientific article published on 01 June 2009

Better safe than sorry: Understanding the toxicological properties of inorganic nanoparticles manufactured for biomedical applications

scientific article published on 10 November 2009

Betulinic acid, a natural cytotoxic agent, fails to trigger apoptosis in human Burkitt's lymphoma-derived B-cell lines

scientific article published on January 2006

Biodegradation of carbon nanotubes by eosinophil peroxidase

scholarly article by Alexander A. Kapralov et al published June 2012 in Toxicology Letters

Biodegradation of single-walled carbon nanotubes by eosinophil peroxidase

journal article published in 2013

Bioinformatics-based cancer research have wide toxicological applicability

Biological interactions of carbon-based nanomaterials: From coronation to degradation

scientific article

Bortezomib and IL-12 produce synergetic anti-multiple myeloma effects with reduced toxicity to natural killer cells

scientific article published on March 2014

Bridge over troubled waters: understanding the synthetic and biological identities of engineered nanomaterials

scientific article published on January 17, 2013

Brief cross-linking of Fas/APO-1 (CD95) triggers engulfment of pre-apoptotic target cells

scientific article published on 18 September 2008

Broaden the discussion

scientific article published on February 1, 2013

Buried alive: a novel approach to cancer treatment

scientific article published on 01 January 2004

Calcium-dependent cyto- and genotoxicity of nickel metal and nickel oxide nanoparticles in human lung cells.

scientific article

Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation

journal article published in 2010

Carbon-based nanomaterials trigger interleukin-1β secretion in human macrophages

Cationic gold nanoparticles elicit mitochondrial dysfunction: a multi-omics study

scientific article published on 13 March 2019

Cell Clearance and Cancer

Central nervous system involvement in severe congenital neutropenia: neurological and neuropsychological abnormalities associated with specific HAX1 mutations.

scientific article published on 29 May 2008

Cerium oxide nanoparticles inhibit differentiation of neural stem cells

scientific article

Classification Framework for Graphene-Based Materials

Clear and present danger? Engineered nanoparticles and the immune system

scientific article published on June 26, 2012

Cleavage of Bcl-2 is an early event in chemotherapy-induced apoptosis of human myeloid leukemia cells

scientific article published on May 1999

Clinical presentation of Griscelli syndrome type 2 and spectrum of RAB27A mutations

scientific article published on April 2010

Close encounters of the small kind: adverse effects of man-made materials interfacing with the nano-cosmos of biological systems

journal article published in 2010

Co-targeting of the PI3K pathway improves the response of BRCA1 deficient breast cancer cells to PARP1 inhibition

scientific article published on 20 January 2012

Cobalt nanoparticles trigger ferroptosis-like cell death (oxytosis) in neuronal cells: Potential implications for neurodegenerative disease

scientific article published on 14 February 2020

Combined spectral karyotyping, comparative genomic hybridization, and in vitro apoptyping of a panel of Burkitt's lymphoma-derived B cell lines reveals an unexpected complexity of chromosomal aberrations and a recurrence of specific abnormalities in

scientific article published on March 2006

Compound heterozygousHAX1mutations in a Swedish patient with severe congenital neutropenia and no neurodevelopmental abnormalities

scientific article published in December 2009

Comprehensive In Vitro Toxicity Testing of a Panel of Representative Oxide Nanomaterials: First Steps towards an Intelligent Testing Strategy

scientific article

Copper oxide nanoparticles trigger macrophage cell death with misfolding of Cu/Zn superoxide dismutase 1 (SOD1)

scientific article published on 10 May 2022

Correction: Phosphatidylserine Targets Single-Walled Carbon Nanotubes to Professional Phagocytes In Vitro and In Vivo

scientific article published on 11 May 2009

Cytokine Profiling of Primary Human Macrophages Exposed to Endotoxin-Free Graphene Oxide: Size-Independent NLRP3 Inflammasome Activation

scientific article published on 21 December 2017

Cytotoxic and Proinflammatory Effects of Metal-Based Nanoparticles on THP-1 Monocytes Characterized by Combined Proteomics Approaches.

scientific article published on 15 December 2016

Cytotoxicity screening and cytokine profiling of nineteen nanomaterials enables hazard ranking and grouping based on inflammogenic potential.

scientific article

DNA origami: self-assembled nucleic acid nanoparticles for siRNA delivery

Degradation of Single-Layer and Few-Layer Graphene by Neutrophil Myeloperoxidase

scientific article published on 01 August 2018

Detection of Endotoxin Contamination of Graphene Based Materials Using the TNF-α Expression Test and Guidelines for Endotoxin-Free Graphene Oxide Production

scientific article

Developing a novel QSAR framework for nanomaterial toxicity

article

Development of multi-drug loaded PEGylated nanodiamonds to inhibit tumor growth and metastasis in genetically engineered mouse models of pancreatic cancer

scientific article published on 01 November 2019

Dexamethasone differentially regulates Bcl-2 family proteins in human proliferative chondrocytes: role of pro-apoptotic Bid.

scientific article

Dichotomous roles for externalized cardiolipin in extracellular signaling: promotion of phagocytosis and attenuation of innate immunity

journal article published in 2015

Differentiation-promoting culture of competent and noncompetent keratinocytes identifies biomarkers for head and neck cancer

scientific article published on 03 December 2011

Direct effects of carbon nanotubes on dendritic cells induce immune suppression upon pulmonary exposure

journal article published in 2011

Don't look back in anger: Lessons from cell death research

scientific article published on 01 December 2019

Doublede novomutations ofELANE(ELA2) in a patient with severe congenital neutropenia requiring high-dose G-CSF therapy

Editorial: Brave new world - Focus on nanomedicine

scientific article published on 28 October 2015

Editorial: Special issue on cell death in honor of Sten Orrenius

scientific article published in January 2017

Effect of FCGR polymorphism on the occurrence of late-onset neutropenia and flare-free survival in rheumatic patients treated with rituximab

scientific article published on 07 March 2017

Efficient internalization of mesoporous silica particles of different sizes by primary human macrophages without impairment of macrophage clearance of apoptotic or antibody-opsonized target cells

scientific article published on 16 June 2009

Efficient internalization of silica-coated iron oxide nanoparticles of different sizes by primary human macrophages and dendritic cells

scientific article published on 22 March 2011

Elevated serum levels of soluble Fas/APO-1 in human immunodeficiency virus-infected individuals

scientific article published in December 1996

Elevated serum levels of the decoy receptor osteoprotegerin in children with Langerhans cell histiocytosis

scientific article published on 01 February 2006

Elimination of the unnecessary: intra- and extracellular signaling by anionic phospholipids

journal article published in 2017

Emerging systems biology approaches in nanotoxicology: Towards a mechanism-based understanding of nanomaterial hazard and risk

scientific article published on 22 December 2015

Enzymatic 'stripping' and degradation of PEGylated carbon nanotubes

scientific article published on 07 November 2014

Epstein-Barr virus-encoded LMP1 promotes cisplatin-induced caspase activation through JNK and NF-kappaB signaling pathways

scientific article

Epstein-Barr virus-encoded latent membrane protein 1 promotes stress-induced apoptosis upstream of caspase-2-dependent mitochondrial perturbation

scientific article published on January 2005

Exploring the anti-apoptotic role of HAX-1 versus BCL-XL in cytokine-dependent bone marrow-derived cells from mice

scientific article

Extracellular entrapment and degradation of single-walled carbon nanotubes

article by Consol Farrera et al published 2014 in Nanoscale

Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos

journal article published in 2012

Familial Hemophagocytic Lymphohistiocytosis: Too Little Cell Death Can Seriously Damage Your Health

scientific article published on June 1, 2001

Familial hemophagocytic lymphohistiocytosis type 3 (FHL3) caused by deep intronic mutation and inversion in UNC13D

scientific article published on 19 September 2011

Fantastic voyage and opportunities of engineered nanomaterials: what are the potential risks of occupational exposures?

journal article published in 2010

Fas-triggered phosphatidylserine exposure is modulated by intracellular ATP.

scientific article

Fat(al) attraction: oxidized lipids act as "eat-me" signals

scientific article published on 22 October 2007

Fibrillar vs crystalline nanocellulose pulmonary epithelial cell responses: cytotoxicity or inflammation?

journal article published in 2017

Fibrous nanocellulose, crystalline nanocellulose, carbon nanotubes, and crocidolite asbestos elicit disparate immune responses upon pharyngeal aspiration in mice

journal article published in 2018

Freewheelin' scientists: citing Bob Dylan in the biomedical literature.

scientific article

Gene expression profiling of immune-competent human cells exposed to engineered zinc oxide or titanium dioxide nanoparticles

scientific article

Genotoxic and epigenetic effects of silver nanoparticles

scholarly article by Hanna L. Karlsson et al published June 2012 in Toxicology Letters

Genotoxicity of carbon nanofibers: are they potentially more or less dangerous than carbon nanotubes or asbestos?

journal article published in 2011

Geoengineering: perilous particles

scientific article published on 01 May 2013

Global phospholipidomics analysis reveals selective pulmonary peroxidation profiles upon inhalation of single-walled carbon nanotubes

journal article published in 2011

Granulocyte colony-stimulating factor inhibits Fas-triggered apoptosis in bone marrow cells isolated from patients with refractory anemia with ringed sideroblasts

scientific article published in May 2001

Granulocyte colony-stimulating factor inhibits spontaneous cytochrome c release and mitochondria-dependent apoptosis of myelodysplastic syndrome hematopoietic progenitors

scientific article published on 5 September 2002

Graphene and other 2D materials: a multidisciplinary analysis to uncover the hidden potential as cancer theranostics

scientific article published on 07 April 2020

Graphene and the Immune System: A Romance of Many Dimensions

scientific article published on 13 June 2017

Graphene oxide attenuates Th2-type immune responses, but augments airway remodeling and hyperresponsiveness in a murine model of asthma

journal article published in 2014

Graphene oxide is degraded by neutrophils and the degradation products are non-genotoxic.

scientific article published on 22 December 2017

Graphene oxide, but not fullerenes, targets immunoproteasomes and suppresses antigen presentation by dendritic cells

journal article published in 2013

Grouping all carbon nanotubes into a single substance category is scientifically unjustified

scientific article published on 01 March 2020

HAX-1 expression in human B lymphoma

scientific article

HAX-1 overexpression in multiple myeloma is associated with poor survival

scientific article published on 19 June 2018

HAX-1: a multifunctional protein with emerging roles in human disease

scientific article published on 12 June 2009

HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease)

scientific article

Hide and Seek: Nanomaterial Interactions With the Immune System

Hollow carbon spheres trigger inflammasome-dependent IL-1β secretion in macrophages

journal article published in 2017

Humanin is a novel regulator of Hedgehog signaling and prevents glucocorticoid-induced bone growth impairment

scientific article published on 18 January 2019

INSIdE NANO: a systems biology framework to contextualize the mechanism-of-action of engineered nanomaterials

scientific article published in Scientific Reports

Immunohistochemical detection of the apoptosis-related proteins FADD, FLICE, and FLIP in Langerhans cell histiocytosis

scientific article published on 01 June 2005

Impaired clearance and enhanced pulmonary inflammatory/fibrotic response to carbon nanotubes in myeloperoxidase-deficient mice

journal article published in 2012

In search of the Holy Grail: Folate-targeted nanoparticles for cancer therapy

scientific article published on 12 February 2011

Incidence of Langerhans cell histiocytosis in children: a population-based study

scientific article published on 01 July 2008

Incidence of severe congenital neutropenia in Sweden and risk of evolution to myelodysplastic syndrome/leukaemia

scholarly article by Göran Carlsson et al published 25 May 2012 in British Journal of Haematology

Increased accumulation of neutrophils and decreased fibrosis in the lung of NADPH oxidase-deficient C57BL/6 mice exposed to carbon nanotubes

journal article published in 2008

Induction of apoptosis and caspase activation in cells obtained from familial haemophagocytic lymphohistiocytosis patients

scientific article published on August 1999

Induction of caspase- and reactive oxygen species-independent phosphatidylserine externalization in primary human neutrophils: role in macrophage recognition and engulfment

scientific article published on 23 December 2008

Interactions of engineered nanoparticles with organs protected by internal biological barriers.

scientific article published on 23 October 2012

Intra- and Extracellular Degradation of Neutrophil Extracellular Traps by Macrophages and Dendritic Cells

scientific article published on 13 September 2019

Involvement of a functional NADPH oxidase in neutrophils and macrophages during programmed cell clearance: implications for chronic granulomatous disease

scientific article

It takes two to tango: Understanding the interactions between engineered nanomaterials and the immune system

scientific article published on 11 March 2015

JAGN1 is required for fungal killing in neutrophil extracellular traps: Implications for severe congenital neutropenia

scientific article published on 14 August 2018

Keeping it real: The importance of material characterization in nanotoxicology

scientific article (publication date: December 2015)

Kostmann syndrome or infantile genetic agranulocytosis, part one: celebrating 50 years of clinical and basic research on severe congenital neutropenia

scientific article published on December 2006

Kostmann syndrome or infantile genetic agranulocytosis, part two: Understanding the underlying genetic defects in severe congenital neutropenia

scientific article published on June 2007

Kostmann syndrome: severe congenital neutropenia associated with defective expression of Bcl-2, constitutive mitochondrial release of cytochrome c, and excessive apoptosis of myeloid progenitor cells

scientific article published on 05 February 2004

Kostmann's syndrome largely elucidated--by Swedish research. 50 years since Rolf Kostmann's pioneering work on severe congenital neutropenia

scientific article published in December 2006

Lactoperoxidase-mediated degradation of single-walled carbon nanotubes in the presence of pulmonary surfactant

scholarly article in Carbon, vol. 91, September 2015

Langerhans cell histiocytosis: new light over pathogenesis. 75 years since Sture Siwe's classic work on "systemic reticuloendotheliosis"

scientific article published in December 2008

Langerhans-cell histiocytosis: neoplasia or unbridled inflammation?

scientific article published on 01 August 2003

Late-onset neutropenia associated with rituximab therapy: evidence for a maturation arrest at the (pro)myelocyte stage of granulopoiesis

scientific article

Late‐onset neutropenia following rituximab therapy in rheumatic diseases: Association with B lymphocyte depletion and infections

scientific article published on August 1, 2011

Lipid antioxidant, etoposide, inhibits phosphatidylserine externalization and macrophage clearance of apoptotic cells by preventing phosphatidylserine oxidation

scientific article published on 20 November 2003

Low plasma levels of the protein pro-LL-37 as an early indication of severe disease in patients with chronic neutropenia

scientific article published in April 2007

MAML1 acts cooperatively with EGR1 to activate EGR1-regulated promoters: implications for nephrogenesis and the development of renal cancer

scientific article

MITCHELL MEDAL LECTURE

scientific article

Macrophage Clearance of Neutrophil Extracellular Traps Is a Silent Process

scientific article published on July 31, 2013

Macrophage activation status determines the internalization of mesoporous silica particles of different sizes: Exploring the role of different pattern recognition receptors

scientific article published on 27 December 2016

Macrophage sensing of single-walled carbon nanotubes via Toll-like receptors

journal article published in 2018

Mapping the Surface Adsorption Forces of Nanomaterials in Biological Systems

scientific article published on October 27, 2011

Mechanism-based genotoxicity screening of metal oxide nanoparticles using the ToxTracker panel of reporter cell lines

scientific article

Mechanisms of carbon nanotube-induced toxicity: focus on oxidative stress

journal article published in 2012

Mechanisms of carbon nanotube-induced toxicity: focus on pulmonary inflammation

scientific article published on 07 June 2013

Mechanisms of pulmonary toxicity and medical applications of carbon nanotubes: two faces of Janus?

journal article published in 2009

Meeting report: BBRC Symposium on Trends in Biochemistry and Biophysics

scientific article published on 01 September 2015

Microsomal glutathione transferase 1 protects against toxicity induced by silica nanoparticles but not by zinc oxide nanoparticles

journal article published in 2012

Morphological properties of nanoporous folic acid materials and in vitro assessment of their biocompatibility

scientific article

Multi-walled carbon nanotubes elicit concordant changes in DNA methylation and gene expression following long-term pulmonary exposure in mice

journal article published in 2021

Multiparametric Profiling of Engineered Nanomaterials: Unmasking the Surface Coating Effect

scientific article published on 11 October 2020

Multiple inherited sequence variations in two disease-causing genes in familial haemophagocytic lymphohistiocytosis

scientific article published on 19 May 2009

N(alpha)-tosyl-L-phenylalanine chloromethyl ketone induces caspase-dependent apoptosis in transformed human B cell lines with transcriptional down-regulation of anti-apoptotic HS1-associated protein X-1.

scientific article

NADPH oxidase-dependent oxidation and externalization of phosphatidylserine during apoptosis in Me2SO-differentiated HL-60 cells. Role in phagocytic clearance

scientific article published on 9 October 2002

Nano på gott och ont: möjligheter och risker med nanoteknologi

scientific article published on 4 July 2017

Nano-bio interactions: a neutrophil-centric view

scientific article published on 29 July 2019

NanoMiner - integrative human transcriptomics data resource for nanoparticle research

scientific article

Nanodrugs to target articular cartilage: An emerging platform for osteoarthritis therapy

scientific article published on 18 December 2015

Nanoparticles and innate immunity: new perspectives on host defence

scientific article published on 28 August 2017

Nanosafety: towards safer design of nanomedicines

scientific article published on 3 October 2013

Nanotoxicology

scientific article published on 21 September 2013

Nanotoxicology: no small matter

scientific article published on September 27, 2010

Neutrophil elastase and granulocyte colony-stimulating factor receptor mutation analyses and leukemia evolution in severe congenital neutropenia patients belonging to the original Kostmann family in northern Sweden

scientific article published on 01 May 2006

Next-Generation Sequencing Reveals Differential Responses to Acute versus Long-Term Exposures to Graphene Oxide in Human Lung Cells

scientific article published on 29 March 2020

Next-Generation Sequencing Reveals Low-Dose Effects of Cationic Dendrimers in Primary Human Bronchial Epithelial Cells

scientific article

Nitric Oxide Dependent Degradation of Polyethylene Glycol-Modified Single-Walled Carbon Nanotubes: Implications for Intra-Articular Delivery

scientific article published on 15 January 2018

Nitric oxide-dependent biodegradation of graphene oxide reduces inflammation in the gastrointestinal tract

scientific article published on 12 August 2020

Nitrosative stress inhibits the aminophospholipid translocase resulting in phosphatidylserine externalization and macrophage engulfment

journal article published in 2007

No small matter: a perspective on nanotechnology-enabled solutions to fight COVID-19

scientific article published on 02 September 2020

Normal levels of constitutive and death receptor-mediated apoptosis of peripheral blood neutrophils from patients with chronic idiopathic neutropenia

scientific article

On the issue of transparency and reproducibility in nanomedicine

scientific article published on 01 July 2019

Ovarian failure in HAX1-deficient patients: is there a gender-specific difference in pubertal development in severe congenital neutropenia or Kostmann disease?

scientific article published in January 2013

Oxidative stress and dermal toxicity of iron oxide nanoparticles in vitro

journal article published in 2013

PD1 blockade enhances cytotoxicity of in vitro expanded natural killer cells towards myeloma cells

scientific article published on 23 June 2016

Perinatal nanomedicine: dendrimer-based therapy for neuroinflammatory disorders

scholarly article by Fernando T Andón et al published 1 September 2012 in Nanomedicine

Phosphatidylserine exposure in Fas type I cells is mitochondria-dependent

scientific article published on June 2003

Phosphatidylserine externalization in cardiolipin-deficient cells

scientific article

Phosphatidylserine targets single-walled carbon nanotubes to professional phagocytes in vitro and in vivo

journal article published in 2009

Plasma membrane alterations during apoptosis: role in corpse clearance

scientific article published on April 2004

Plasma membrane sequestration of apoptotic protease-activating factor-1 in human B-lymphoma cells: a novel mechanism of chemoresistance.

scientific article published on 3 February 2005

Preface

publication published in 2017

Preface

preface of "Adverse effects of engineered nanomaterials", published in 2012

Proapoptotic effects of the novel proteasome inhibitor b-AP15 on multiple myeloma cells and natural killer cells

scientific article published on 27 November 2013

Programmed Cell Death: Molecular Mechanisms and Implications for Safety Assessment of Nanomaterials

scientific article published on June 21, 2012

Programmed cell clearance: From nematodes to humans

scientific article published on 2 December 2016

Programmed cell clearance: molecular regulation of the elimination of apoptotic cell corpses and its role in the resolution of inflammation

scientific article

Proteasome inhibition induces apoptosis in primary human natural killer cells and suppresses NKp46-mediated cytotoxicity

scientific article published on 19 February 2009

Proteasome inhibition up-regulates p53 and apoptosis-inducing factor in chondrocytes causing severe growth retardation in mice

scientific article published in October 2007

Proteomics Analysis Reveals Distinct Corona Composition on Magnetic Nanoparticles with Different Surface Coatings: Implications for Interactions with Primary Human Macrophages

scientific article published on 07 October 2015

Publisher Correction: On the issue of transparency and reproducibility in nanomedicine

scientific article published on 01 August 2019

Publisher Correction: On the issue of transparency and reproducibility in nanomedicine

scientific article published on 01 September 2019

Pulmonary exposure to single-walled carbon nanotubes does not affect the early immune response against Toxoplasma gondii

journal article published in 2012

RNA-sequencing reveals long-term effects of silver nanoparticles on human lung cells

scientific article published on 27 April 2018

Raji revisited: cytogenetics of the original Burkitt's lymphoma cell line

scientific article published on January 2005

Recent nanomedicine articles of outstanding interest

scientific article published on 01 July 2015

Requirement of apoptotic protease-activating factor-1 for bortezomib-induced apoptosis but not for Fas-mediated apoptosis in human leukemic cells

scientific article published on 23 October 2012

Research highlights: Highlights from the last year in nanomedicine

scientific article published in January 2014

Retraction. Neutrophil elastase mutations in severe congenital neutropenia patients of the original Kostmann family

scientific article published on 16 January 2003

Safety Assessment of Graphene-Based Materials: Focus on Human Health and the Environment

article

Safety assessment of nanomaterials: implications for nanomedicine.

scientific article published on 25 January 2012

Scythe cleavage during Fas (APO‐1)‐and staurosporine‐mediated apoptosis

scientific article published on January 26, 2012

Sequence analysis of the granulysin and granzyme B genes in familial hemophagocytic lymphohistiocytosis

scientific article (publication date: 2003)

Sequence analysis of theSRGN, AP3B1, ARF6, andSH2D1A genes in familial hemophagocytic lymphohistiocytosis

article

Severe congenital neutropenia-associated JAGN1 mutations unleash a calpain-dependent cell death programme in myeloid cells

scientific article published on 18 November 2020

Shifting identities of metal oxide nanoparticles: Focus on inflammation

Single-Walled Carbon Nanotubes Inhibit the Cytochrome P450 Enzyme, CYP3A4.

scientific article

Single-walled carbon nanotubes impair human macrophage engulfment of apoptotic cell corpses

journal article published in 2009

Size-Dependent Pulmonary Impact of Thin Graphene Oxide Sheets in Mice: Toward Safe-by-Design

scientific article published on 07 May 2020

Size-dependent cytotoxicity of silver nanoparticles in human lung cells: the role of cellular uptake, agglomeration and Ag release

scientific article published on 17 February 2014

Skeletal Mineralization Deficits and Impaired Biogenesis and Function of Chondrocyte-Derived Matrix Vesicles in Phospho1(-/-) and Phospho1/Pi t1 Double-Knockout Mice.

scientific article published on 15 January 2016

Smac-mediated sensitization of human B-lymphoma cells to staurosporine- and lactacystin-triggered apoptosis is apoptosome-dependent

scientific article published on 22 March 2007

Solution-Engineered Palladium Nanoparticles: Model for Health Effect Studies of Automotive Particulate Pollution

scientific article published on June 13, 2011

Spectrum and clinical implications of syntaxin 11 gene mutations in familial haemophagocytic lymphohistiocytosis: association with disease-free remissions and haematopoietic malignancies

scientific article published in April 2006

Spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosis

scientific article

Spectrum, and clinical and functional implications of UNC13D mutations in familial haemophagocytic lymphohistiocytosis

scientific article published in March 2008

Stability and biocompatibility of a library of polyester dendrimers in comparison to polyamidoamine dendrimers

scientific article published on December 15, 2011

Stromal-derived factor-1 abolishes constitutive apoptosis of WHIM syndrome neutrophils harbouring a truncating CXCR4 mutation

scientific article published on 9 August 2006

Structure and function analysis of the C. elegans aminophospholipid translocase TAT-1

scientific article published on 28 February 2019

Survivin expression in the bone marrow of patients with severe congenital neutropenia

scientific article published on 25 September 2008

Syntaxin-11 is expressed in primary human monocytes/macrophages and acts as a negative regulator of macrophage engulfment of apoptotic cells and IgG-opsonized target cells

scientific article published on 11 June 2008

Systems biology in nanosafety research

scientific article published on 01 January 2015

Targeted uptake of folic acid-functionalized iron oxide nanoparticles by ovarian cancer cells in the presence but not in the absence of serum

scientific article published on 31 January 2014

The Potential Role of Apoptosis in Human Disease

The Right Stuff: On the Future of Nanotoxicology

scientific article published on 26 November 2019

The bio-nano-interface in predicting nanoparticle fate and behaviour in living organisms: towards grouping and categorising nanomaterials and ensuring nanosafety by design

scholarly article published 1 January 2013

The eNanoMapper database for nanomaterial safety information

scientific article

The eNanoMapper database for nanomaterial safety information

The first eNanoMapper prototype: A substance database to support safe-by-design

scientific article (publication date: November 2014)

The importance of size: nanomedicine for delivery of anticancer drugs in solid tumors

scientific article published in September 2012

The ins and outs of phospholipid asymmetry in the plasma membrane: roles in health and disease

scientific article published on September 2009

The most unkindest cut of all: on the multiple roles of mammalian caspases

scientific article

The proteasome inhibitor bortezomib disrupts tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression and natural killer (NK) cell killing of TRAIL receptor-positive multiple myeloma cells

scientific article published on 9 June 2010

There's plenty of room at the forum: potential risks and safety assessment of engineered nanomaterials

journal article published in 2007

Three cell deaths and a funeral: macrophage clearance of cells undergoing distinct modes of cell death

article by Katharina Klöditz & Bengt Fadeel published 2019 in Cell death discovery

Towards the clinic: intelligent design of nanomedicines for cancer treatment

scientific article published in September 2012

Toxicity of surface-modified copper oxide nanoparticles in a mouse macrophage cell line: Interplay of particles, surface coating and particle dissolution

scientific article published on 29 December 2017

Toxicology of engineered nanomaterials: focus on biocompatibility, biodistribution and biodegradation

scientific article published on 08 May 2010

Transcriptional profiling reveals gene expression changes associated with inflammation and cell proliferation following short-term inhalation exposure to copper oxide nanoparticles

scientific article published on 2 November 2017

Trimodal imaging of brain tumors using multifunctional nanoparticles

Tumor selective uptake of drug-nanodiamond complexes improves therapeutic outcome in pancreatic cancer

scientific article published on 06 March 2019

Two pathways of apoptosis induced with all-trans retinoic acid and etoposide in the myeloid cell line P39.

scientific article published on August 1999

VEGF reduces astrogliosis and preserves neuromuscular junctions in ALS transgenic mice

scientific article published on 01 October 2007

VR-3848, a novel peptide derived from Euphobiaceae, induces mitochondria-dependent apoptosis in human leukemia cells

scientific article published on May 2004

Vascular endothelial growth factor prolongs survival in a transgenic mouse model of ALS.

scientific article published in October 2004

Vitamin D fails to prevent serum starvation- or staurosporine-induced apoptosis in human and rat osteosarcoma-derived cell lines

scientific article

Water-soluble superparamagnetic magnetite nanoparticles with biocompatible coating for enhanced magnetic resonance imaging

scientific article

[Enigmatic diseases in children. Still a lot of questions left in spite of great research progress on LCH and HLH]

scientific article published on 01 May 2005

eNanoMapper – A database and ontology framework for design and safety assessment of nanomaterials

‘Centennial’ Nobel Conference on apoptosis and human disease

Adverse effects of engineered nanomaterials

hardcover edition (en)