List of works - Roland Grafström

A data fusion pipeline for generating and enriching Adverse Outcome Pathway descriptions

scientific article published on 15 November 2017

A novel infrastructure for chemical safety predictions with focus on human health

A transcriptomics data-driven gene space accurately predicts liver cytopathology and drug-induced liver injury

scientific article from 2017

Arsenic alters global histone modifications in lymphocytes in vitro and in vivo

scientific article

Arsenic-induced suppression of kidney cell proliferation and the transcriptional coregulator MAML1.

scientific article published on 28 January 2014

Bioinformatics processing of protein and transcript profiles of normal and transformed cell lines indicates functional impairment of transcriptional regulators in buccal carcinoma

scientific article published on 15 August 2007

CD44 expression in oro-pharyngeal carcinoma tissues and cell lines

scientific article

Cancer Biology, Toxicology and Alternative Methods Development Go Hand-in-Hand

scientific article (publication date: 23 May 2014)

Chapter 11. Computational Modelling of Biological Responses to Engineered Nanomaterials

Combining factors on protein and gene level to predict radioresponse in head and neck cancer cell lines ⬇️

scientific article published on April 11, 2011

Comparative hazard characterization in food toxicology

scientific article published on August 2009

Computational toxicology using OpenTox & Bioclipse

Computational toxicology using the OpenTox application programming interface and Bioclipse

scientific article

Consumption of Red/Processed Meat and Colorectal Carcinoma: Possible Mechanisms Underlying the Significant Association

scientific article published on 07 April 2015

Cytotoxicity, thiol depletion and inhibition of O6-methylguanine-DNA methyltransferase by various aldehydes in cultured human bronchial fibroblasts

scientific article

Developing a novel QSAR framework for nanomaterial toxicity

article

Differentiation-promoting culture of competent and noncompetent keratinocytes identifies biomarkers for head and neck cancer

scientific article published on 03 December 2011

ELIXIR and Toxicology: a community in development

scientific article published on 3 October 2023

Enriching Nanomaterials Omics Data: An Integration Technique to Generate Biological Descriptors

scientific article published on 12 October 2017

Fibronectin 1 is a potential biomarker for radioresistance in head and neck squamous cell carcinoma ⬇️

scientific article published on December 15, 2010

Formaldehyde dehydrogenase: beyond phase I metabolism

scientific article published on 4 December 2009

High throughput toxicity screening and intracellular detection of nanomaterials

scientific article (publication date: 7 June 2016)

High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth

scientific article

Integrated analysis of in vitro data and the adverse outcome pathway framework for prioritization and regulatory applications: An exploratory case study using publicly available data on piperonyl butoxide and liver models

scholarly article by Noffisat O. Oki et al published February 2019 in Toxicology in Vitro

Interactive predictive toxicology with Bioclipse and OpenTox ⬇️

Introducing WikiPathways as a Data-Source to Support Adverse Outcome Pathways for Regulatory Risk Assessment of Chemicals and Nanomaterials

scientific article published on 21 December 2018

Introducing WikiPathways to link molecular pathways to adverse outcome pathways to support regulatory risk assessment

scientific article

Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models

scientific article published on 26 September 2011

MAML1 acts cooperatively with EGR1 to activate EGR1-regulated promoters: implications for nephrogenesis and the development of renal cancer

scientific article

Matrix metalloproteinase-7 and -13 expression associate to cisplatin resistance in head and neck cancer cell lines

scientific article published on 12 May 2009

Medium-chain fatty acids and glutathione derivatives as inhibitors of S-nitrosoglutathione reduction mediated by alcohol dehydrogenase 3.

scientific article published on 29 January 2009

Microarray assessment of fibronectin, collagen and integrin expression and the role of fibronectin-collagen coating in the growth of normal, SV40 T-antigen-immortalised and malignant human oral keratinocytes

scientific article

Modelling of normal and premalignant oral tissue by using the immortalised cell line, SVpgC2a: a review of the value of the model

scientific article

Multiple genotypic aberrances associate to terminal differentiation-deficiency of an oral squamous cell carcinoma in serum-free culture

scientific article published on 29 April 2008

NanoSolveIT Project: Driving nanoinformatics research to develop innovative and integrated tools for in silico nanosafety assessment

scientific article published on 07 March 2020

Probabilistic toxicogenomics studies in vitro

RDFIO: extending Semantic MediaWiki for interoperable biomedical data management

scientific article

Reduction of S-nitrosoglutathione by alcohol dehydrogenase 3 is facilitated by substrate alcohols via direct cofactor recycling and leads to GSH-controlled formation of glutathione transferase inhibitors

scientific article

Reliable Surface Analysis Data of Nanomaterials in Support of Risk Assessment Based on Minimum Information Requirements

Requirement of apoptotic protease-activating factor-1 for bortezomib-induced apoptosis but not for Fas-mediated apoptosis in human leukemic cells

scientific article published on 23 October 2012

Sharing dose response data and analysis across the SEURAT-1 cluster

The Janus face of alcohol dehydrogenase 3

scientific article

The ToxBank Data Warehouse: Supporting the Replacement of In Vivo Repeated Dose Systemic Toxicity Testing

scientific article (publication date: 2013)

The eNanoMapper database for nanomaterial safety information

scientific article

The eNanoMapper database for nanomaterial safety information

The first eNanoMapper prototype: A substance database to support safe-by-design ⬇️

scientific article (publication date: November 2014)

Toward Rigorous Materials Production: New Approach Methodologies Have Extensive Potential to Improve Current Safety Assessment Practices

scientific article published on 08 January 2020

Towards FAIR nanosafety data

Toxic and Genomic Influences of Inhaled Nanomaterials as a Basis for Predicting Adverse Outcome.

scientific article published in April 2018

Transcriptomics in Toxicogenomics, Part I: Experimental Design, Technologies, Publicly Available Data, and Regulatory Aspects

scientific article published on 15 April 2020

Transcriptomics in Toxicogenomics, Part II: Preprocessing and Differential Expression Analysis for High Quality Data

scientific article published on 08 May 2020

Transcriptomics in Toxicogenomics, Part III: Data Modelling for Risk Assessment

scientific article published on 08 April 2020

YAP1 is a potential biomarker for cetuximab resistance in head and neck cancer

scientific article

eNanoMapper – A database and ontology framework for design and safety assessment of nanomaterials

toxFlow: a Web-Based Application for Read-Across Toxicity Prediction using Omics and Physicochemical Data.

scientific article published on 27 December 2017

List of works by Roland Grafström

A data fusion pipeline for generating and enriching Adverse Outcome Pathway descriptions

A novel infrastructure for chemical safety predictions with focus on human health

A transcriptomics data-driven gene space accurately predicts liver cytopathology and drug-induced liver injury

Arsenic alters global histone modifications in lymphocytes in vitro and in vivo

Arsenic-induced suppression of kidney cell proliferation and the transcriptional coregulator MAML1.

Bioinformatics processing of protein and transcript profiles of normal and transformed cell lines indicates functional impairment of transcriptional regulators in buccal carcinoma

CD44 expression in oro-pharyngeal carcinoma tissues and cell lines

Cancer Biology, Toxicology and Alternative Methods Development Go Hand-in-Hand

Chapter 11. Computational Modelling of Biological Responses to Engineered Nanomaterials

Combining factors on protein and gene level to predict radioresponse in head and neck cancer cell lines ⬇️

Comparative hazard characterization in food toxicology

Computational toxicology using OpenTox & Bioclipse

Computational toxicology using the OpenTox application programming interface and Bioclipse

Consumption of Red/Processed Meat and Colorectal Carcinoma: Possible Mechanisms Underlying the Significant Association

Cytotoxicity, thiol depletion and inhibition of O6-methylguanine-DNA methyltransferase by various aldehydes in cultured human bronchial fibroblasts

Developing a novel QSAR framework for nanomaterial toxicity

Differentiation-promoting culture of competent and noncompetent keratinocytes identifies biomarkers for head and neck cancer

ELIXIR and Toxicology: a community in development

ELIXIR and Toxicology: a community in development

Enriching Nanomaterials Omics Data: An Integration Technique to Generate Biological Descriptors

Fibronectin 1 is a potential biomarker for radioresistance in head and neck squamous cell carcinoma ⬇️

Formaldehyde dehydrogenase: beyond phase I metabolism

High throughput toxicity screening and intracellular detection of nanomaterials

High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth

Integrated analysis of in vitro data and the adverse outcome pathway framework for prioritization and regulatory applications: An exploratory case study using publicly available data on piperonyl butoxide and liver models

Interactive predictive toxicology with Bioclipse and OpenTox ⬇️

Introducing WikiPathways as a Data-Source to Support Adverse Outcome Pathways for Regulatory Risk Assessment of Chemicals and Nanomaterials

Introducing WikiPathways to link molecular pathways to adverse outcome pathways to support regulatory risk assessment

Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models

MAML1 acts cooperatively with EGR1 to activate EGR1-regulated promoters: implications for nephrogenesis and the development of renal cancer

Matrix metalloproteinase-7 and -13 expression associate to cisplatin resistance in head and neck cancer cell lines

Medium-chain fatty acids and glutathione derivatives as inhibitors of S-nitrosoglutathione reduction mediated by alcohol dehydrogenase 3.

Microarray assessment of fibronectin, collagen and integrin expression and the role of fibronectin-collagen coating in the growth of normal, SV40 T-antigen-immortalised and malignant human oral keratinocytes

Modelling of normal and premalignant oral tissue by using the immortalised cell line, SVpgC2a: a review of the value of the model

Multiple genotypic aberrances associate to terminal differentiation-deficiency of an oral squamous cell carcinoma in serum-free culture

NanoSolveIT Project: Driving nanoinformatics research to develop innovative and integrated tools for in silico nanosafety assessment

Probabilistic toxicogenomics studies in vitro

RDFIO: extending Semantic MediaWiki for interoperable biomedical data management

Reduction of S-nitrosoglutathione by alcohol dehydrogenase 3 is facilitated by substrate alcohols via direct cofactor recycling and leads to GSH-controlled formation of glutathione transferase inhibitors

Reliable Surface Analysis Data of Nanomaterials in Support of Risk Assessment Based on Minimum Information Requirements

Requirement of apoptotic protease-activating factor-1 for bortezomib-induced apoptosis but not for Fas-mediated apoptosis in human leukemic cells

Sharing dose response data and analysis across the SEURAT-1 cluster

The Janus face of alcohol dehydrogenase 3

The ToxBank Data Warehouse: Supporting the Replacement of In Vivo Repeated Dose Systemic Toxicity Testing

The eNanoMapper database for nanomaterial safety information

The eNanoMapper database for nanomaterial safety information

The first eNanoMapper prototype: A substance database to support safe-by-design ⬇️

Toward Rigorous Materials Production: New Approach Methodologies Have Extensive Potential to Improve Current Safety Assessment Practices

Towards FAIR nanosafety data

Toxic and Genomic Influences of Inhaled Nanomaterials as a Basis for Predicting Adverse Outcome.

Transcriptomics in Toxicogenomics, Part I: Experimental Design, Technologies, Publicly Available Data, and Regulatory Aspects

Transcriptomics in Toxicogenomics, Part II: Preprocessing and Differential Expression Analysis for High Quality Data

Transcriptomics in Toxicogenomics, Part III: Data Modelling for Risk Assessment

YAP1 is a potential biomarker for cetuximab resistance in head and neck cancer

eNanoMapper – A database and ontology framework for design and safety assessment of nanomaterials

toxFlow: a Web-Based Application for Read-Across Toxicity Prediction using Omics and Physicochemical Data.