Search filters

List of works by Jerzy Pałka

Acetylenic derivative of betulin induces apoptosis in endometrial adenocarcinoma cell line

scientific article published on 29 August 2017

Acetylsalicylic acid as a potential regulator of prolidase-convertible pro-drugs in control and neoplastic cells

scientific article (publication date: September 2004)

Acetylsalicylic acid prevents nickel-induced collagen biosynthesis in human fibroblasts.

scientific article published on 22 July 2005

Amidine analogue of chlorambucil is a stronger inhibitor of protein and DNA synthesis in breast cancer MCF-7 cells than is the parent drug.

scientific article

Amino Acid Profiles of Serum and Urine in Search for Prostate Cancer Biomarkers: a Pilot Study.

scientific article published on January 2017

An accumulation of IGF-I and IGF-binding proteins in human umbilical cord.

scientific article published on March 2000

An expression of IGF-binding proteins in normal and pre-eclamptic human umbilical cord serum and tissues

scientific article published on 01 August 2002

Betulinic acid inhibits the expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor in human endometrial adenocarcinoma cells.

scientific article

Butyrate-induced collagen biosynthesis in cultured fibroblasts is independent on alpha2beta1 integrin signalling and undergoes through IGF-I receptor cascade.

scientific article published on 16 March 2006

Collagen metabolism disturbances are accompanied by an increase in prolidase activity in lung carcinoma planoepitheliale

scientific article published on 01 October 2000

Constituents of Propolis: Chrysin, Caffeic Acid, p-Coumaric Acid, and Ferulic Acid Induce PRODH/POX-Dependent Apoptosis in Human Tongue Squamous Cell Carcinoma Cell (CAL-27).

scientific article

Cross-talk between integrin receptor and insulin-like growth factor receptor in regulation of collagen biosynthesis in cultured fibroblasts.

scientific article published on January 2013

Cytotoxicity and effect on collagen biosynthesis of proline analogue of melphalan as a prolidase-convertible prodrug in cultured human skin fibroblasts.

scientific article published in September 2001

Decrease in the glycosaminoglycan content in the skin of diabetic rats. The role of IGF-I, IGF-binding proteins and proteolytic activity

scientific article published on 01 January 1996

Decreased biosynthesis of glycosaminoglycans in the skin of rats with chronic diabetes mellitus

scientific article published on 01 May 1999

Decreased expression of the insulin-like growth factor-I-binding protein-1 (IGFBP-1) phosphoisoform in pre-eclamptic Wharton's jelly and its role in the regulation of collagen biosynthesis.

scientific article published in February 2004

Development of an LC-MS Targeted Metabolomics Methodology to Study Proline Metabolism in Mammalian Cell Cultures

scientific article published on 12 October 2020

Differences and similarities in the phenomenon of NETs formation in oral inflammation and in oral squamous cell carcinoma.

scientific article

Differential effect of platelet-rich plasma fractions on β1-integrin signaling, collagen biosynthesis, and prolidase activity in human skin fibroblasts.

scientific article published on 22 June 2017

Differential effects of echistatin and thrombin on collagen production and prolidase activity in human dermal fibroblasts and their possible implication in beta1-integrin-mediated signaling.

scientific article published in March 2005

Doxycycline-induced inhibition of prolidase activity in human skin fibroblasts and its involvement in impaired collagen biosynthesis.

scientific article published in October 2001

Effect of melanin on netilmicin-induced inhibition of collagen biosynthesis in human skin fibroblasts

scientific article published on 28 September 2006

Enalapril stimulates collagen biosynthesis through prolidase-dependent mechanism in cultured fibroblasts.

scientific article published on 17 March 2015

Enhanced prolidase activity and decreased collagen content in breast cancer tissue

scientific article published on 01 August 2006

Exogenous proline stimulates type I collagen and HIF-1α expression and the process is attenuated by glutamine in human skin fibroblasts

scientific article published on 19 May 2017

Expression of IGF-binding protein-1 phosphoisoforms in fasted rat skin and its role in regulation of collagen biosynthesis.

scientific article published in April 2003

Fasting-induced inhibition of collagen biosynthesis in rat skin. A possible role for phosphoenolpyruvate in this process

scientific article published in October 2004

Fibroblast chemotaxis and prolidase activity modulation by insulin-like growth factor II and mannose 6-phosphate

scientific article published on 01 March 1997

Functional Consequences of Intracellular Proline Levels Manipulation Affecting PRODH/POX-Dependent Pro-Apoptotic Pathways in a Novel in Vitro Cell Culture Model.

scientific article

Glucose-depleted medium reduces the collagen content of human skin fibroblast cultures.

scientific article published on 22 June 2007

HIF-1 α as a Key Factor in Bile Duct Ligation-Induced Liver Fibrosis in Rats.

scientific article published on 3 June 2016

Hyaluronic acid abrogates nitric oxide-dependent stimulation of collagen degradation in cultured human chondrocytes.

scientific article

Hyaluronic acid counteracts interleukin-1-induced inhibition of collagen biosynthesis in cultured human chondrocytes

scientific article published on 30 June 2006

Insulin-like growth factor I-dependent regulation of prolidase activity in cultured human skin fibroblasts.

scientific article

LC-QTOF-MS and 1H NMR Metabolomics Verifies Potential Use of Greater Omentum for Klebsiella pneumoniae Biofilm Eradication in Rats

scientific article published on 21 May 2020

Melanin counter act puromycin-induced inhibition of collagen and DNA biosynthesis in human skin fibroblasts

scientific article published on 12 February 2005

Melanin potentiates daunorubicin-induced inhibition of collagen biosynthesis in human skin fibroblasts.

scientific article

Melanin potentiates gentamicin-induced inhibition of collagen biosynthesis in human skin fibroblasts.

scientific article published in June 2002

Metformin Treatment or PRODH/POX-Knock out Similarly Induces Apoptosis by Reprograming of Amino Acid Metabolism, TCA, Urea Cycle and Pentose Phosphate Pathway in MCF-7 Breast Cancer Cells

scientific article published on 15 December 2021

New potential biomarkers of acetaminophen-induced hepatotoxicity.

scientific article

Novel amidine analogue of melphalan as a specific multifunctional inhibitor of growth and metabolism of human breast cancer cells.

scientific article published on 4 May 2006

Phenotype variability in a daughter and father with mild osteogenesis imperfecta correlated with collagen and prolidase levels in cultured skin fibroblasts.

scientific article published in January 2005

Phosphoenolpyruvate-dependent inhibition of collagen biosynthesis, alpha2beta1 integrin and IGF-I receptor signaling in cultured fibroblasts.

scientific article published on 21 May 2008

Plasma and liver amino acids in rats after administration of ethanol or acetaldehyde

scientific article published on 01 October 1986

Potential role of beta 1 integrin and collagen biosynthesis in estrogen-dependent reduction of apoptosis in tamoxifen-treated breast cancer cells.

scientific article published in January 2001

Preeclampsia is associated with alterations in insulin-like growth factor (IGF)-1 and IGF-binding proteins in Wharton's jelly of the umbilical cord

scientific article published on 01 July 2000

Prolidase Stimulates Proliferation and Migration through Activation of the PI3K/Akt/mTOR Signaling Pathway in Human Keratinocytes

scientific article published on 03 December 2020

Prolidase activity in fibroblasts is regulated by interaction of extracellular matrix with cell surface integrin receptors

scientific article (publication date: November 1997)

Prolidase dependent inhibition of collagen biosynthesis in Chinese hamster ovary cells.

scientific article published on 11 June 2008

Prolidase in human breast cancer MCF-7 cells.

scientific article published in May 1998

Prolidase-dependent mechanism of (Z)-8,9-epoxyheptadeca-1,11,14-triene-induced inhibition of collagen biosynthesis in cultured human skin fibroblasts.

scientific article

Prolidase-dependent regulation of TGF β (corrected) and TGF β receptor expressions in human skin fibroblasts.

scientific article published on 21 September 2010

Prolidase-independent mechanism of camptothecin-induced inhibition of collagen biosynthesis in cultured human skin fibroblasts.

scientific article published on 14 December 2006

Prolidase-proline dehydrogenase/proline oxidase-collagen biosynthesis axis as a potential interface of apoptosis/autophagy.

scientific article published on 4 April 2016

Proline Oxidase (POX) as A Target for Cancer Therapy.

scientific article published on January 2015

Proline analogue of melphalan as a prodrug susceptible to the action of prolidase in breast cancer MDA-MB 231 cells.

scientific article published on November 2003

Proline oxidase silencing induces proline-dependent pro-survival pathways in MCF-7 cells.

scientific article

Proline oxidase silencing inhibits p53-dependent apoptosis in MCF-7 breast cancer cells

scientific article published on 04 June 2021

Protective effect of hyaluronic acid on interleukin-1-induced deregulation of beta1-integrin and insulin-like growth factor-I receptor signaling and collagen biosynthesis in cultured human chondrocytes.

scientific article published on 25 September 2007

Salt stimulation of serum insulin-like growth factor binding protein activity

scientific article published on 01 December 1988

Scutellarin-dependent inhibition of collagen biosynthesis in cultured fibroblasts

scientific article published on 11 July 2011

Similar hormonal changes in sera from scorbutic and fasted (vitamin C-supplemented) guinea pigs, including decreased IGF-I and appearance of an IGF-I reversible mitogenic inhibitor.

scientific article published on January 1989

The effect of Telmisartan on collagen biosynthesis depends on the status of estrogen activation in breast cancer cells.

scientific article

The effect of prolactin and estrogen cross-talk on prolidase- dependent signaling in MCF-7 cells.

scientific article published on January 2013

The mechanism for differential effect of nelfinavir and indinavir on collagen metabolism in human skin fibroblasts

scientific article published on 06 June 2019

The mechanism of hydralazine-induced collagen biosynthesis in cultured fibroblasts ⬇️

scientific article published on January 24, 2013

The mechanism of oxythiamine-induced collagen biosynthesis in cultured fibroblasts

scientific article published on 28 January 2015

Thrombin-dependent modulation of β1-integrin-mediated signaling up-regulates prolidase and HIF-1α through p-FAK in colorectal cancer cells

scientific article published on 13 October 2011

UVC inhibits collagen biosynthesis through up-regulation of NF-κB p65 signaling in cultured fibroblasts.

scientific article

Understanding the role of key amino acids in regulation of proline dehydrogenase/proline oxidase (prodh/pox)-dependent apoptosis/autophagy as an approach to targeted cancer therapy

scientific article published on 13 January 2020

αIIbβ3-integrin Ligands: Abciximab and Eptifibatide as Proapoptotic Factors in MCF-7 Human Breast Cancer Cells

scientific article published on 01 January 2015

Paulina is supported by:

About Paulina

Help