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List of works by Bryan Williams

(-)-Epigallocatechin-3-gallate and EZH2 inhibitor GSK343 have similar inhibitory effects and mechanisms of action on colorectal cancer cells.

scientific article published on 19 September 2017

(-)-Epigallocatechin-3-gallate and atorvastatin treatment down-regulates liver fibrosis related genes in non-alcoholic fatty liver disease

scientific article

1H, 13C, 15N resonance assignment of the 20 kDa double stranded RNA binding domain of PKR

scientific article published on 01 August 1998

A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis

scientific article

A non-canonical function of Ezh2 preserves immune homeostasis.

scientific article published on 21 February 2017

A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells.

scientific article published on 30 April 2006

A systematic search for downstream mediators of tumor suppressor function of p53 reveals a major role of BTG2 in suppression of Ras-induced transformation

scientific article published in January 2006

A transcriptional signaling pathway in the IFN system mediated by 2'-5'-oligoadenylate activation of RNase L.

scientific article

ARED 2.0: an update of AU-rich element mRNA database.

scientific article published on January 2003

ARED 3.0: the large and diverse AU-rich transcriptome.

scientific article

ARED: human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteins

scientific article

ATF3 Repression of BCL-XL Determines Apoptotic Sensitivity to HDAC Inhibitors across Tumor Types.

scientific article published on 13 June 2017

AU-rich transient response transcripts in the human genome: expressed sequence tag clustering and gene discovery approach.

scientific article

Activating Transcription Factor 3 Expression as a Marker of Response to the Histone Deacetylase Inhibitor Pracinostat

scientific article published on 25 April 2016

Activating transcription factor 3 contributes to Toll-like receptor-mediated macrophage survival via repression of Bax and Bak.

scientific article published on 22 May 2013

Activation of a nuclease by pppA2′p5′ A2′p5′ A in intact cells

scientific article published on September 1, 1979

Activation of cGAS-dependent antiviral responses by DNA intercalating agents

scientific article published on 29 September 2016

Activation of p38 mitogen-activated protein kinase and c-Jun NH(2)-terminal kinase by double-stranded RNA and encephalomyocarditis virus: involvement of RNase L, protein kinase R, and alternative pathways.

scientific article

Activation of the interferon system by short-interfering RNAs

scientific article (publication date: September 2003)

Activation of the mammalian immune system by siRNAs.

scientific article

Alphavirus minus-strand synthesis and persistence in mouse embryo fibroblasts derived from mice lacking RNase L and protein kinase R.

scientific article

Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways

scientific article

Analysis of genes induced by Sendai virus infection of mutant cell lines reveals essential roles of interferon regulatory factor 3, NF-kappaB, and interferon but not toll-like receptor 3

scientific article

Analysis of microRNA turnover in mammalian cells following Dicer1 ablation.

scientific article

Analysis of the wilms tumor suppressor geneWT1 in endometrial carcinoma

article

Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis

scientific journal article

Auto-phosphorylation Represses Protein Kinase R Activity

scientific article published on 10 March 2017

BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs.

scientific article

Basal expression of the gene (TIMP) encoding the murine tissue inhibitor of metalloproteinases is mediated through AP1- and CCAAT-binding factors

scientific article published on July 15, 1992

Blockade of interferon induction and action by the E3L double-stranded RNA binding proteins of vaccinia virus.

scientific article

Blockage of NF-kappa B signaling by selective ablation of an mRNA target by 2-5A antisense chimeras

scientific article published in Science

C114 is a novel IL-11-inducible nuclear double-stranded RNA-binding protein that inhibits protein kinase R

scientific journal article

Cell cycle regulation of the double stranded RNA activated protein kinase, PKR

scientific article published on 01 January 1999

Cellular retinoic acid-binding protein II is a direct transcriptional target of MycN in neuroblastoma.

scientific article published on August 2006

Central Role of Double-Stranded RNA-Activated Protein Kinase in Microbial Induction of Nitric Oxide Synthase

scientific article published on 01 July 2000

Characterization of a 500-kb contig spanning the region between c-Ha-Ras and MUC2 on chromosome 11p15.5

scientific article (publication date: 15 October 2000)

Characterization of the gene encoding the 100-kDa form of human 2',5' oligoadenylate synthetase.

scientific article

Characterization of the solution complex between the interferon-induced, double-stranded RNA-activated protein kinase and HIV-I trans-activating region RNA.

scientific article published in April 1997

Constitutional and somatic deletions of two different regions of maternal chromosome 11 in Wilms tumor.

scientific article published on July 1990

Constitutive expression of the Wilms tumor suppressor gene (WT1) in renal cell carcinoma

article

Cystic Fibrosis and Normal Human Airway Epithelial Cell Response to Influenza A Viral Infection

article

Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB

scientific article

Definition of the limits of the Wilms tumor locus on human chromosome 11p13.

scientific article

Deletion of WT1 and WIT1 genes and loss of heterozygosity on chromosome 11p in Wilms tumors in Japan

scientific article published in June 1993

Derivation and characterization of a Wilms' tumour cell line, WiT 49.

scientific article published on November 2003

Detection of double-stranded RNA in Semliki Forest virus-infected cells by an indirect solid phase radioimmunoassay: an assay for interferon

scientific article published on January 1, 1977

Differential binding of human interferon-α subtypes to receptors on lymphoblastoid cells

scientific article published on 01 January 1983

Differential expression in clear cell renal cell carcinoma identified by gene expression profiling.

scientific article published on 17 December 2008

Differential expression of E-cadherin and beta catenin in primary and metastatic Wilms's tumours

scientific article

Differential human interferon alpha receptor expression on proliferating and non-proliferating cells

scientific article published on 01 May 1986

Differentiating the interferon pathway

scientific article published on 01 September 2010

Distinct roles of protein kinase R and toll-like receptor 3 in the activation of astrocytes by viral stimuli

scientific article published on 01 February 2007

Distinctive roles for 2',5'-oligoadenylate synthetases and double-stranded RNA-dependent protein kinase R in the in vivo antiviral effect of an adenoviral vector expressing murine IFN-beta.

scientific article

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

scientific article published on July 1994

Downregulation of interferon alpha but not gamma receptor expression in vivo in the acquired immunodeficiency syndrome

scientific article published on October 1988

Dynamic Flexibility of Double-stranded RNA Activated PKR in Solution

scientific article published on 05 April 2006

Dynamiting Viruses with MxA

scientific article published on 01 October 2011

Editorial

scholarly article by Bryan R Williams published in March 2002

Efficient suppression of secretory clusterin levels by polymer-siRNA nanocomplexes enhances ionizing radiation lethality in human MCF-7 breast cancer cells in vitro.

scientific article published on January 2006

Enlarged spleens without enlarged lymph nodes in tlr3-/- pkr-/- mice

scientific article published on 01 January 2007

Expressed gene clusters associated with cellular sensitivity and resistance towards anti-viral and anti-proliferative actions of interferon.

scientific article published on September 2004

Expression and localization of HGF and met in Wilms' tumours

scientific article published on January 1, 2002

Expression of IFITM1 in chronic myeloid leukemia patients.

scientific article

Fine tuning type I interferon responses

scientific article published on May 25, 2013

Fine-tuning of the innate immune response by microRNAs.

scientific article published on 10 July 2007

Functional differences in the promoters of the interferon-inducible (2'-5')A oligoadenylate synthetase and 6-16 genes in interferon-resistant Daudi cells.

scientific article published on January 1994

Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains.

scientific article

Gene Modulatory Effects, Pharmacokinetics, and Clinical Tolerance of Interferon-α1b: A Second Member of the Interferon-α Family

article

Genetic modulation of TLR8 response following bacterial phagocytosis.

scientific article published on September 2010

Genomic Features of HumanPKR:Alternative Splicing and a Polymorphic CGG Repeat in the 5′-Untranslated Region

scientific article published on August 1, 1998

HDACi: molecular mechanisms and therapeutic implications in the innate immune system

scientific article published on November 15, 2011

HIV-1 TAR RNA has an intrinsic ability to activate interferon-inducible enzymes.

scientific article published in November 1994

Heterogeneity in control of mRNA stability by AU-rich elements.

scientific article published on 28 January 2003

High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.

scientific article

How cells respond to interferons

scientific article (publication date: 1998)

Human Toll-like receptor 8 can be cool too: implications for foreign RNA sensing

scientific article

Human immunodeficiency virus-1/surface glycoprotein 120 induces apoptosis through RNA-activated protein kinase signaling in neurons.

scientific article published in October 2007

IL-10 regulates Aicda expression through miR-155

scientific article

Identification of Critical Residues Required for Suppressor of Cytokine Signaling-specific Regulation of Interleukin-4 Signaling

scientific article published in Journal of Biological Chemistry

Identification of a histone family gene signature for predicting the prognosis of cervical cancer patients.

scientific article published on 28 November 2017

Identification of double-stranded RNA-binding domains in the interferon-induced double-stranded RNA-activated p68 kinase

scientific article published on June 15, 1992

Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

scientific journal article

Impaired Innate Host Defense Causes Susceptibility to Respiratory Virus Infections in Cystic Fibrosis

scientific article published on May 1, 2003

Induction of E-Selectin Expression by Double-Stranded RNA and TNF- Is Attenuated in Murine Aortic Endothelial Cells Derived from Double-Stranded RNA-Activated Kinase (PKR)-Null Mice

scientific article published on 01 February 2000

Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity.

scholarly article

Inhibition of cell-free protein synthesis by pppA2′ p5′ A2′ p5′ A: a novel oligonucleotide synthesized by interferon-treated L cell extracts

scientific article published on 01 March 1978

Inhibition of protein synthesis by 2′–5′ linked adenine oligonucleotides in intact cells

scientific article published in Nature

Inosine-mediated modulation of RNA sensing by Toll-like receptor 7 (TLR7) and TLR8.

scientific article

Integrin-Linked Kinase Expression in Myeloid Cells Promotes Inflammatory Signaling during Experimental Colitis.

scientific article published on 9 August 2017

Integrin-linked kinase modulates lipopolysaccharide- and Helicobacter pylori-induced nuclear factor κB-activated tumor necrosis factor-α production via regulation of p65 serine 536 phosphorylation

scientific article

Interferon action in triply deficient mice reveals the existence of alternative antiviral pathways.

scientific article

Interferon and growth factor modulation of nuclear factors binding to 5? upstream elements of the 2-5A synthetase gene

article

Interferon and phorbol esters down-regulate sIgM expression by independent pathways.

scientific article published in February 1988

Interferon gamma and interleukin 4 stimulate prolonged expression of inducible nitric oxide synthase in human airway epithelium through synthesis of soluble mediators.

scientific article published on August 1997

Interferon-Stimulated Genes and Their Protein Products: What and How?

scientific article published on January 1, 2011

Interferon-alpha activates binding of nuclear factors to a sequence element in the c-fos proto-oncogene 5'-flanking region

scientific article published on October 1, 1992

Interferon-regulated human 2-5A synthetase gene maps to chromosome 12.

scientific article

Interferon-regulated pathways that control hepatitis B virus replication in transgenic mice.

scientific article

Interferons induce an antiviral state in human pancreatic islet cells

scientific article published on 08 June 2007

Involvement of Double-stranded RNA-activated Protein Kinase in the Synergistic Activation of Nuclear Factor-κB by Tumor Necrosis Factor-α and γ-Interferon in Preneuronal Cells

scientific article published in Journal of Biological Chemistry

Involvement of the interferon-regulated antiviral proteins PKR and RNase L in reovirus-induced shutoff of cellular translation.

scientific article published on February 2005

JNK2 and IKKbeta are required for activating the innate response to viral infection

scientific article

Latest advances in innate antiviral defence.

scientific article published on March 2009

Localization of the Human Interferon-Induced, ds-RNA Activated p68 Kinase Gene (PRKR) to Chromosome 2p21-p22

scientific article published on June 1, 1993

Loss of heterozygosity at chromosome 11p15 in Wilms tumors: identification of two independent regions

scientific article published on 01 July 1998

Loss of heterozygosity mapping in Wilms tumor indicates the involvement of three distinct regions and a limited role for nondisjunction or mitotic recombination

scientific article published on November 1, 1992

Lysophosphatidic acid downregulates tissue inhibitor of metalloproteinases, which are negatively involved in lysophosphatidic acid-induced cell invasion

scientific article published on 27 November 2006

Making sense of viral RNA sensing.

scientific article published on September 2011

Microsatellite instability at a single locus (D11S988) on chromosome 11p15.5 as a late event in mammary tumorigenesis.

scientific article published in October 1995

Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages

scientific article published on 05 March 2021

Modified vaccinia virus Ankara can activate NF-kappaB transcription factors through a double-stranded RNA-activated protein kinase (PKR)-dependent pathway during the early phase of virus replication

scientific article published on September 2009

Molecular characterization of cytogenetic alterations associated with the Beckwith — Wiedemann syndrome (BWS) phenotype refines the localization and suggests the gene for BWS is imprinted

article

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

scientific article

Molecular cloning of cDNAs from androgen-independent mRNA species of DBA/2 mouse sub-maxillary glands.

scientific article

Molecular dynamics reveal a novel kinase-substrate interface that regulates protein translation.

scientific article published on 17 November 2014

Monitoring Innate Immune Recruitment by siRNAs in Mammalian Cells

scientific article published on 01 January 2010

Multiple tumor suppressor genes in multistep carcinogenesis.

scientific article published in October 1992

Mutational analysis of the double-stranded RNA (dsRNA) binding domain of the dsRNA-activated protein kinase, PKR.

scientific article published on February 1995

Mutations in the Double-stranded RNA-activated Protein Kinase Insert Region That Uncouple Catalysis from eIF2α Binding

scientific article published in Journal of Biological Chemistry

NF-kappaB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-kappaB-inducing kinase and IkappaB kinase

scientific article

Natural occurrence of 2-5A in interferon-treated EMC virus-infected L cells

scientific article published on December 6, 1979

Negative Regulation of CD8+ T Cell Function by the IFN-Induced and Double-Stranded RNA-Activated Kinase PKR

scientific article published on 01 December 2000

Novel interferon-beta-induced gene expression in peripheral blood cells.

scientific article published on 20 August 2007

OAS and PKR are not required for the antiviral effect of Ad:IFN-gamma against acute HSV-1 in primary trigeminal ganglia cultures.

scientific article

PKR-dependent and -independent mechanisms are involved in translational shutoff during Sindbis virus infection.

scientific article published on August 2004

PKR: proposed nomenclature for the RNA-dependent protein kinase induced by interferon.

scientific article published in June 1993

PKR; a sentinel kinase for cellular stress

scientific article (publication date: November 1999)

Patterns of coordinate down-regulation of ARE-containing transcripts following immune cell activation.

scientific article published in December 2004

Phospholipid scramblase 1 potentiates the antiviral activity of interferon

scientific article

Promyelocytic leukemia zinc finger protein regulates interferon-mediated innate immunity

scientific article published on 11 June 2009

Protein kinase R (PKR) interacts with and activates mitogen-activated protein kinase kinase 6 (MKK6) in response to double-stranded RNA stimulation

scientific article

Protein kinase R and the inflammasome.

scientific article

Protein kinase R-dependent regulation of interleukin-10 in response to double-stranded RNA.

scientific article published on 14 July 2008

Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4- and IL-13-dependent signal transduction.

scientific article published on December 1998

RNA interference and double-stranded-RNA-activated pathways

scientific article

RNA interference in biology and disease

scientific article

RNA-dependent protein kinase PKR is required for activation of NF-kappa B by IFN-gamma in a STAT1-independent pathway.

scientific article published on May 2001

RNA-dependent protein kinase is required for alpha-1 interferon transgene-induced resistance to genital herpes simplex virus type 2.

scientific article

RNase L and double-stranded RNA-dependent protein kinase exert complementary roles in islet cell defense during coxsackievirus infection.

scientific article published in February 2005

RNase L mediates transient control of the interferon response through modulation of the double-stranded RNA-dependent protein kinase PKR.

scientific article published on 11 February 2003

Rational design of immunostimulatory siRNAs.

scientific article

Receptor-associated constitutive protein tyrosine phosphatase activity controls the kinase function of JAK1.

scientific article published on August 1997

Reduced expression of autotaxin predicts survival in uveal melanoma.

scientific article

Regulation of Actin Dynamics by Protein Kinase R Control of Gelsolin Enforces Basal Innate Immune Defense

scientific article published on May 25, 2012

Regulation of CRABP-II expression by MycN in Wilms tumor.

scientific article

Regulation of Tumor Necrosis Factor Receptor Expression by Acid-Labile Interferon-α from AIDS Sera

article

Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways.

scientific article published on January 2000

Regulation of double-stranded RNA dependent protein kinase expression and attenuation of protein synthesis induced by bacterial toll-like receptors agonists in the absence of interferon.

scientific article

Regulation of interferon receptor expression in human blood lymphocytes in vitro and during interferon therapy

scientific article

Replication of Hepatitis C Virus (HCV) RNA in Mouse Embryonic Fibroblasts: Protein Kinase R (PKR)-Dependent and PKR-Independent Mechanisms for Controlling HCV RNA Replication and Mediating Interferon Activities

scientific article

Response and resistance to interferons and interacting cytokines.

scientific article published on February 1995

Review of recent developments in the molecular characterization of recombinant alfa interferons on the 40th anniversary of the discovery of interferon.

scientific article

Role of PKR and Type I IFNs in viral control during primary and secondary infection.

scientific article

Roles of Protein-tyrosine Phosphatases in Stat1 -mediated Cell Signaling

scientific article published in Journal of Biological Chemistry

Sequence-dependent off-target inhibition of TLR7/8 sensing by synthetic microRNA inhibitors

scientific article

Signal integration via PKR.

scientific article

Signal transduction and transcriptional regulation of interferon-alpha-stimulated genes.

scientific article published on August 1991

Specific binding of the ETS-domain protein to the interferon-stimulated response element.

scientific article published on January 1997

Stability of CXCL-8 and related AU-rich mRNAs in the context of hepatitis C virus replication in vitro.

scientific article published on 13 February 2006

Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA-mediated activation

scientific article published on September 15, 1998

Subcellular localization of the von Hippel-Lindau disease gene product is cell cycle-dependent

scientific article published on September 25, 1998

Surgical margins in head and neck squamous cell carcinoma: Effect of heat artifact on immunohistochemistry as a future tool for assessment.

scientific article

Synthesis and Breakdown of pppA2'p5'A2'p5'A and Transient Inhibition of Protein Synthesis in Extracts from Interferon-Treated and Control Cells

scientific article published on December 1, 1978

TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages.

scientific article published on 18 March 2002

Targeting specific cell types with silencing RNA.

scientific article published in September 2005

Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs.

scientific article

The B56alpha regulatory subunit of protein phosphatase 2A is a target for regulation by double-stranded RNA-dependent protein kinase PKR

scientific article

The Interferon-Induced Double-Stranded RNA-Activated Human p68 Protein Kinase Potently Inhibits Protein Synthesis in Cultured Cells

scientific article published on 01 January 1993

The Promyelocytic Leukemia Zinc Finger Protein: Two Decades of Molecular Oncology

scientific article published on July 17, 2012

The acetyltransferase HAT1 moderates the NF-κB response by regulating the transcription factor PLZF.

scientific article published on 13 April 2015

The distal region of 11p13 and associated genetic diseases

scientific article published on 01 October 1991

The effect of interferon on cells deficient in nucleoside transport or lacking thymidine kinase activity

scientific article published on 01 January 1984

The innate immune receptor MDA5 limits rotavirus infection but promotes cell death and pancreatic inflammation

scientific article

The interaction of interferon-α and -γ: Regulation of (2–5)A synthetase activity

scientific article published on 01 July 1988

The lack of RNA-dependent protein kinase enhances susceptibility of mice to genital herpes simplex virus type 2 infection.

scientific article published in August 2006

The molecular genetics of Wilms tumor.

scientific article

The murine 2-5A synthetase locus: three distinct transcripts from two linked genes

scientific article published on April 25, 1991

The p59 oligoadenylate synthetase-like protein possesses antiviral activity that requires the C-terminal ubiquitin-like domain

scientific article

The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development

scientific article

The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin

scientific article

The respective roles of the protein kinase and pppA2' p5' A2' p5 A-activated endonuclease in the inhibition of protein synthesis by double stranded RNA in rabbit reticulocyte lysates

scientific article published on April 1, 1979

The role of Ets2 transcription factor in the induction of microRNA-155 (miR-155) by lipopolysaccharide and its targeting by interleukin-10

scientific article published on 20 December 2013

The use of miRNA microarrays for the analysis of cancer samples with global miRNA decrease

scientific article published on 24 May 2013

Tissue-specific and inducer-specific differential induction of ISG56 and ISG54 in mice.

scientific article

Tissue-specific regulation of theWT1 locus

scientific article published on 01 November 1996

Topoisomerase 1 Inhibition Promotes Cyclic GMP-AMP Synthase-Dependent Antiviral Responses.

scientific article published on 3 October 2017

Transcript profiling of Wilms tumors reveals connections to kidney morphogenesis and expression patterns associated with anaplasia.

scientific article published in January 2005

Transcriptional Activation of Inflammatory Genes: Mechanistic Insight into Selectivity and Diversity

scientific article

Transcriptional regulation of interferon-stimulated genes

scientific article published on August 15, 1991

Translational control perks up

scientific article published in Nature

Tumor Cell Response to Synchrotron Microbeam Radiation Therapy Differs Markedly From Cells in Normal Tissues

article

Two distinct tumor suppressor loci within chromosome 11p15 implicated in breast cancer progression and metastasis

scientific article published on 01 May 1998

Type I Interferon Induction Pathway, but Not Released Interferon, Participates in the Maturation of Dendritic Cells Induced by Negative‐Strand RNA Viruses

scientific article published on 19 March 2003

Type I interferon inhibits antibody responses induced by a chimpanzee adenovirus vector.

scientific article published in February 2007

Understanding immune phenotypes in human gastric disease tissues by multiplexed immunohistochemistry

scientific article published on 12 October 2017

Vascular endothelial growth factor (VEGF) is suppressed in WT1-transfected LNCaP cells

scientific article published in January 2006

Viral apoptosis is induced by IRF-3-mediated activation of Bax

scientific article

Wilms tumor locus on 11p13 defined by multiple CpG island-associated transcripts

scientific article

Wilms' tumor as a model for cancer biology

scientific article

X chromosome inactivation of the human TIMP gene.

scientific article published in July 1990

p38 Mitogen-activated protein kinase-dependent and -independent signaling of mRNA stability of AU-rich element-containing transcripts

scientific article

p53, bcl-2, and Bax Expression in Renal Cell Carcinoma

scientific article published on June 1, 1998

siRNA delivery not Toll-free

scientific article published on 01 October 2009

siRNA-induced immunostimulation through TLR7 promotes antitumoral activity against HPV-driven tumors in vivo.

scientific article published on 22 March 2011

“Endogenous adjuvant” activity of the RNA components of lupus autoantigens Sm/RNP and Ro 60

article