List of works - Tim Stearns

A crucial requirement for Hedgehog signaling in small cell lung cancer

scientific article

A high-enrollment course-based undergraduate research experience improves student conceptions of scientific thinking and ability to interpret data

scientific article

ADP-ribosylation factor is functionally and physically associated with the Golgi complex

scientific article

Adenomatous polyposis coli and EB1 localize in close proximity of the mother centriole and EB1 is a functional component of centrosomes.

scientific article

Analysis of Tub4p, a yeast gamma-tubulin-like protein: implications for microtubule-organizing center function

scientific article

At the heart of the organizing center.

scientific article

Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites

scientific article

Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole-cilium interface and facilitates proper cilium formation and function

scientific article

Cell architecture: putting the building blocks together

scientific article published on 30 December 2012

Cell biology. Centrioles, in absentia.

scientific article

Cellular structures

scientific article published on 01 September 1992

Centriole triplet microtubules are required for stable centriole formation and inheritance in human cells.

scientific article

Centrioles are amplified in cycling progenitors of olfactory sensory neurons

scientific article published on 15 September 2020

Centrosomal deployment of gamma-tubulin and pericentrin: evidence for a microtubule-nucleating domain and a minus-end docking domain in certain mouse epithelial cells

scientific article published on 01 January 1997

Centrosome-kinase fusions promote oncogenic signaling and disrupt centrosome function in myeloproliferative neoplasms

scientific article

Centrosomes isolated from Spisula solidissima oocytes contain rings and an unusual stoichiometric ratio of alpha/beta tubulin.

scientific article

Cep120 is asymmetrically localized to the daughter centriole and is essential for centriole assembly.

scientific article

Cep152 interacts with Plk4 and is required for centriole duplication.

scientific article

Cilium Axoneme Internalization and Degradation in Chytrid Fungi

scientific article published on 26 October 2020

Cilium structure, assembly, and disassembly regulated by the cytoskeleton

scientific article published on 31 July 2018

Curcumin inhibits growth of Saccharomyces cerevisiae through iron chelation

scientific article published on 9 September 2011

Cyclin-dependent kinase control of centrosome duplication

scientific article

Cyclin-dependent kinase control of motile ciliogenesis

article published in 2018

Cytoskeleton: anatomy of an organizing center.

scientific article published on December 1997

DNA topoisomerase II must act at mitosis to prevent nondisjunction and chromosome breakage.

scientific article

Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function

scientific article

Dispatch. Centrosome biology: a SAS-sy centriole in the cell cycle.

scientific article

Diverse biological functions of small GTP-binding proteins in yeast

scientific article published on 01 January 1988

Evaluation of approaches to detect quantitative trait loci for growth, carcass, and meat quality on swine chromosomes 2, 6, 13, and 18. I. Univariate outbred F2 and sib-pair analyses

scientific article published on 01 July 2005

Evaluation of approaches to detect quantitative trait loci for growth, carcass, and meat quality on swine chromosomes 2, 6, 13, and 18. II. Multivariate and principal component analyses

scientific article published on 01 November 2005

Exploring the pole: an EMBO conference on centrosomes and spindle pole bodies

scientific article published in December 2008

Expression of amino- and carboxyl-terminal gamma- and alpha-tubulin mutants in cultured epithelial cells.

scientific article published in January 1998

FOP is a centriolar satellite protein involved in ciliogenesis

scientific article

GCP5 and GCP6: two new members of the human gamma-tubulin complex

scientific article

Gamma-tubulin complexes: size does matter.

scientific article

Genetic analysis of lung function in inbred mice suggests vitamin D receptor as a candidate gene ⬇️

scientific article published on August 19, 2011

How physician/administrator teams work in small groups. Six steps to make it happen

scientific article published on 01 May 1999

In vitro reconstitution of centrosome assembly and function: the central role of gamma-tubulin

scientific article

Investigate the origins of COVID-19

scientific article

Journey to the center of the centrosome

scientific article published on March 2014

Long-range migration of centrioles to the apical surface of the olfactory epithelium

scientific article published in 2022

MDM1 is a microtubule-binding protein that negatively regulates centriole duplication

scientific journal article

Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure

scientific article

Mechanosensing by the primary cilium: deletion of Kif3A reduces bone formation due to loading

scientific article

Microtubule-organizing centres: a re-evaluation.

scientific article published on February 2007

Microtubules orient the mitotic spindle in yeast through dynein-dependent interactions with the cell cortex.

scientific article

Mitosis sans Mitosis: The Mitotic Oscillator in Differentiation

scientific article published in November 2017

Molecular characterization of centriole assembly in ciliated epithelial cells

scientific article

Motoring to the finish: kinesin and dynein work together to orient the yeast mitotic spindle.

scientific article published on September 1997

Mutational analysis of Saccharomyces cerevisiae ARF1

scientific article published on 01 January 1995

Myb promotes centriole amplification and later steps of the multiciliogenesis program.

scientific article

Nucleation and capture of large cell surface‐associated microtubule arrays that are not located near centrosomes in certain cochlear epithelial cells ⬇️

scientific article published on January 1, 1998

Observing planar cell polarity in multiciliated mouse airway epithelial cells

scientific article published on 7 March 2015

Parallel analysis of genetic selections using whole genome oligonucleotide arrays.

scientific article

Plk1-dependent recruitment of gamma-tubulin complexes to mitotic centrosomes involves multiple PCM components

scientific article

Polo kinase and separase regulate the mitotic licensing of centriole duplication in human cells.

scientific article

Primary cilia in bone.

scientific article

Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism.

scientific article

Primary cilium loss in mammalian cells occurs predominantly by whole-cilium shedding

scientific article published on 17 July 2019

Probing mammalian centrosome structure using BioID proximity-dependent biotinylation

scientific article

Proteomic analysis of mammalian sperm cells identifies new components of the centrosome

scientific article

Proximity interactions among centrosome components identify regulators of centriole duplication

scientific article published on 6 March 2014

Regulation of cilia abundance in multiciliated cells

scientific article published on 26 April 2019

Remembrance of cilia past.

scientific article

STED Super-resolution Microscopy in Drosophila Tissue and in Mammalian Cells

scientific article published on February 2011

Sperm Centrosomes: Kiss Your Asterless Goodbye, for Fertility's Sake

scientific article published on 01 December 2015

Spindle positioning and cell polarity.

scientific article published in September 1992

Supernumerary centrosomes nucleate extra cilia and compromise primary cilium signaling

scientific article

Synaptically coupled central nervous system neurons lack centrosomal gamma-tubulin

scientific article published on 01 June 1997

The ABCs of Centriole Architecture: The Form and Function of Triplet Microtubules.

scientific article published on 14 March 2018

The Cell Center at 100 ⬇️

scientific article published on October 31, 1997

The Life Cycle of Centrioles ⬇️

scientific article published on January 1, 2010

The Mammalian γ-Tubulin Complex Contains Homologues of the Yeast Spindle Pole Body Components Spc97p and Spc98p ⬇️

scientific article published on May 4, 1998

The Rilp-like proteins Rilpl1 and Rilpl2 regulate ciliary membrane content.

scientific article

The centriole duplication cycle

scientific article

The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries

scientific article

The cytoskeleton of Saccharomyces cerevisiae.

scientific article published on February 1990

The nucleus serves as the pacemaker for the cell cycle

scientific article published on 07 December 2020

The primary cilium: what once did nothing, now does everything.

scientific article published in October 2007

Transcriptional program of ciliated epithelial cells reveals new cilium and centrosome components and links to human disease

scientific journal article

Tubulin Subunits Exist in an Activated Conformational State Generated and Maintained by Protein Cofactors ⬇️

scientific article published on August 25, 1997

Using yeast to determine the functional consequences of mutations in the human p53 tumor suppressor gene: An introductory course-based undergraduate research experience in molecular and cell biology

scientific article published on 22 November 2016

Zeta-Tubulin Is a Member of a Conserved Tubulin Module and Is a Component of the Centriolar Basal Foot in Multiciliated Cells

scientific article

gamma-Tubulin

scientific article published on 01 June 2002

γ-Tubulin is a highly conserved component of the centrosome ⬇️

scientific article published on May 31, 1991

List of works by Tim Stearns

A crucial requirement for Hedgehog signaling in small cell lung cancer

A high-enrollment course-based undergraduate research experience improves student conceptions of scientific thinking and ability to interpret data

ADP-ribosylation factor is functionally and physically associated with the Golgi complex

Adenomatous polyposis coli and EB1 localize in close proximity of the mother centriole and EB1 is a functional component of centrosomes.

Analysis of Tub4p, a yeast gamma-tubulin-like protein: implications for microtubule-organizing center function

At the heart of the organizing center.

Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites

Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole-cilium interface and facilitates proper cilium formation and function

Cell architecture: putting the building blocks together

Cell biology. Centrioles, in absentia.

Cellular structures

Centriole triplet microtubules are required for stable centriole formation and inheritance in human cells.

Centrioles are amplified in cycling progenitors of olfactory sensory neurons

Centrosomal deployment of gamma-tubulin and pericentrin: evidence for a microtubule-nucleating domain and a minus-end docking domain in certain mouse epithelial cells

Centrosome-kinase fusions promote oncogenic signaling and disrupt centrosome function in myeloproliferative neoplasms

Centrosomes isolated from Spisula solidissima oocytes contain rings and an unusual stoichiometric ratio of alpha/beta tubulin.

Cep120 is asymmetrically localized to the daughter centriole and is essential for centriole assembly.

Cep152 interacts with Plk4 and is required for centriole duplication.

Cilium Axoneme Internalization and Degradation in Chytrid Fungi

Cilium structure, assembly, and disassembly regulated by the cytoskeleton

Curcumin inhibits growth of Saccharomyces cerevisiae through iron chelation

Cyclin-dependent kinase control of centrosome duplication

Cyclin-dependent kinase control of motile ciliogenesis

Cytoskeleton: anatomy of an organizing center.

DNA topoisomerase II must act at mitosis to prevent nondisjunction and chromosome breakage.

Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function

Dispatch. Centrosome biology: a SAS-sy centriole in the cell cycle.

Diverse biological functions of small GTP-binding proteins in yeast

Evaluation of approaches to detect quantitative trait loci for growth, carcass, and meat quality on swine chromosomes 2, 6, 13, and 18. I. Univariate outbred F2 and sib-pair analyses

Evaluation of approaches to detect quantitative trait loci for growth, carcass, and meat quality on swine chromosomes 2, 6, 13, and 18. II. Multivariate and principal component analyses

Exploring the pole: an EMBO conference on centrosomes and spindle pole bodies

Expression of amino- and carboxyl-terminal gamma- and alpha-tubulin mutants in cultured epithelial cells.

FOP is a centriolar satellite protein involved in ciliogenesis

GCP5 and GCP6: two new members of the human gamma-tubulin complex

Gamma-tubulin complexes: size does matter.

Genetic analysis of lung function in inbred mice suggests vitamin D receptor as a candidate gene ⬇️

How physician/administrator teams work in small groups. Six steps to make it happen

In vitro reconstitution of centrosome assembly and function: the central role of gamma-tubulin

Investigate the origins of COVID-19

Journey to the center of the centrosome

Long-range migration of centrioles to the apical surface of the olfactory epithelium

MDM1 is a microtubule-binding protein that negatively regulates centriole duplication

Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure

Mechanosensing by the primary cilium: deletion of Kif3A reduces bone formation due to loading

Microtubule-organizing centres: a re-evaluation.

Microtubules orient the mitotic spindle in yeast through dynein-dependent interactions with the cell cortex.

Mitosis sans Mitosis: The Mitotic Oscillator in Differentiation

Molecular characterization of centriole assembly in ciliated epithelial cells

Motoring to the finish: kinesin and dynein work together to orient the yeast mitotic spindle.

Mutational analysis of Saccharomyces cerevisiae ARF1

Myb promotes centriole amplification and later steps of the multiciliogenesis program.

Nucleation and capture of large cell surface‐associated microtubule arrays that are not located near centrosomes in certain cochlear epithelial cells ⬇️

Observing planar cell polarity in multiciliated mouse airway epithelial cells

Parallel analysis of genetic selections using whole genome oligonucleotide arrays.

Plk1-dependent recruitment of gamma-tubulin complexes to mitotic centrosomes involves multiple PCM components

Polo kinase and separase regulate the mitotic licensing of centriole duplication in human cells.

Primary cilia in bone.

Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism.

Primary cilium loss in mammalian cells occurs predominantly by whole-cilium shedding

Probing mammalian centrosome structure using BioID proximity-dependent biotinylation

Proteomic analysis of mammalian sperm cells identifies new components of the centrosome

Proximity interactions among centrosome components identify regulators of centriole duplication

Regulation of cilia abundance in multiciliated cells

Remembrance of cilia past.

STED Super-resolution Microscopy in Drosophila Tissue and in Mammalian Cells

Sperm Centrosomes: Kiss Your Asterless Goodbye, for Fertility's Sake

Spindle positioning and cell polarity.

Supernumerary centrosomes nucleate extra cilia and compromise primary cilium signaling

Synaptically coupled central nervous system neurons lack centrosomal gamma-tubulin

The ABCs of Centriole Architecture: The Form and Function of Triplet Microtubules.

The Cell Center at 100 ⬇️

The Life Cycle of Centrioles ⬇️

The Mammalian γ-Tubulin Complex Contains Homologues of the Yeast Spindle Pole Body Components Spc97p and Spc98p ⬇️

The Rilp-like proteins Rilpl1 and Rilpl2 regulate ciliary membrane content.

The centriole duplication cycle

The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries

The cytoskeleton of Saccharomyces cerevisiae.

The nucleus serves as the pacemaker for the cell cycle

The primary cilium: what once did nothing, now does everything.