Search filters

List of works by Heinz Wiendl

"Chronic cerebrospinal venous insufficiency" and multiple sclerosis: critical analysis and first observation in an unselected cohort of MS patients

scientific article

14-3-3 Proteins regulate K2P 5.1 surface expression on T lymphocytes.

scientific article published on 15 October 2016

4-Aminopyridine ameliorates mobility but not disease course in an animal model of multiple sclerosis

article

4-aminopyridine is not just a symptomatic therapy, it has a neuroprotective effect - No

scientific article published on 06 July 2020

7. Stomach examination using the gastrocamera

scientific article published on 01 January 1967

A Novel PKD1 Mutation Associated With Autosomal Dominant Kidney Disease and Cerebral Cavernous Malformation.

scientific article published on 25 May 2018

A PD-1 polymorphism is associated with disease progression in multiple sclerosis.

scientific article

A beta-lactam antibiotic dampens excitotoxic inflammatory CNS damage in a mouse model of multiple sclerosis

scientific article

A case of idiopathic multicentric Castleman disease in an alemtuzumab-treated patient with MS

scientific article published on 08 November 2019

A fatal case of daclizumab-induced liver failure in a patient with MS

scientific article published on 21 January 2019

A functional role of HLA-G expression in human gliomas: an alternative strategy of immune escape

scientific article

A human post-mortem brain model for the standardization of multi-centre MRI studies.

scientific article

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

article by Sven J. van der Lee et al published 27 May 2019 in Acta Neuropathologica

A novel automated segmentation method for retinal layers in OCT images proves retinal degeneration after optic neuritis.

scientific article published on 25 August 2015

A novel homozygous missense mutation in the GNE gene of a patient with quadriceps-sparing hereditary inclusion body myopathy associated with muscle inflammation

scientific article published in December 2003

ALAIN01--Alemtuzumab in autoimmune inflammatory neurodegeneration: mechanisms of action and neuroprotective potential.

scientific article

Abrasion cytology of the stomach (author's transl) ⬇️

scientific article published on July 11, 1975

Abstract 458: Immune-inhibitory HLA-G is expressed in the tumor microenvironment of Ewing Sarcomas

Accelerated course of experimental autoimmune encephalomyelitis in PD-1-deficient central nervous system myelin mutants

scientific article

Action of treosulfan in myelin-oligodendrocyte-glycoprotein-induced experimental autoimmune encephalomyelitis and human lymphocytes

scientific article published in November 2003

Active immunization induces toxicity of diphtheria toxin in diphtheria resistant mice--implications for neuroinflammatory models

scientific article published on 04 February 2010

Active immunization with proteolipid protein (190-209) induces ascending paralysing experimental autoimmune encephalomyelitis in C3H/HeJ mice

scientific article published on 31 December 2010

Acute cholecystitis during treatment with alemtuzumab in 3 patients with RRMS.

scientific article published on 28 October 2016

Acute disseminated encephalomyelitis: an update

scientific article

Acute transverse myelitis associated with coxiella burnetii infection

scientific article published on 01 October 2002

Advances in pathogenic concepts and therapeutic agents in Rasmussen's encephalitis

scientific article

Alemtuzumab Improves Cognitive Processing Speed in Active Multiple Sclerosis-A Longitudinal Observational Study

scientific article published in January 2017

Alemtuzumab in Multiple Sclerosis: Mechanism of Action and Beyond

scientific article

Alemtuzumab therapy changes immunoglobulin levels in peripheral blood and CSF

scientific article published on 11 December 2019

Alemtuzumab treatment alters circulating innate immune cells in multiple sclerosis

scientific article published on 12 October 2016

Alemtuzumab-induced immune phenotype and repertoire changes: implications for secondary autoimmunity

scientific article published on 21 February 2022

Altered neuronal expression of TASK1 and TASK3 potassium channels in rodent and human autoimmune CNS inflammation

scientific article published in December 2008

Amygdala enlargement and emotional responses in (autoimmune) temporal lobe epilepsy.

scientific article

Amyotrophic lateral sclerosis patients show increased peripheral and intrathecal T-cell activation

scientific article published on 14 July 2021

An Assay to Determine Mechanisms of Rapid Autoantibody-Induced Neurotransmitter Receptor Endocytosis and Vesicular Trafficking in Autoimmune Encephalitis

An Enigmatic Case of Acute Mercury Poisoning: Clinical, Immunological Findings and Platelet Function.

scientific article published on 28 September 2017

An In Vitro Model of the Blood-brain Barrier Using Impedance Spectroscopy: A Focus on T Cell-endothelial Cell Interaction

scientific article published on 8 December 2016

An assay to quantify species-specific anti-JC virus antibody levels in MS patients

scientific article published on 6 February 2013

An autoreactive gamma delta TCR derived from a polymyositis lesion

scientific article published on 01 July 2002

An enigmatic case of cortical anopsia: Antemortem diagnosis of a 14-3-3 negative Heidenhain-variant MM1-sCJD

scientific article published on 01 December 2020

An ex vivo model of an oligodendrocyte-directed T-cell attack in acute brain slices

scientific article published on 5 February 2015

An imbalance of two functionally and phenotypically different subsets of plasmacytoid dendritic cells characterizes the dysfunctional immune regulation in multiple sclerosis

scientific article published on 31 March 2010

Analysis of Lymphocyte Extravasation Using an In Vitro Model of the Human Blood-brain Barrier

scientific article

Analysis of the C/T(-1) single nucleotide polymorphism in the CD40 gene in multiple sclerosis

scientific article published on 01 October 2006

Animal models in idiopathic inflammatory myopathies: How to overcome a translational roadblock?

scientific article published on 07 March 2017

Anti-JC virus antibody prevalence in a multinational multiple sclerosis cohort

scientific article published on 4 March 2013

Anti-JC-virus antibody prevalence in a German MS cohort

scientific article

Anti-JCV serology during natalizumab treatment: Review and meta-analysis of 17 independent patient cohorts analyzing anti-John Cunningham polyoma virus sero-conversion rates under natalizumab treatment and differences between technical and biologica

scientific article

Antigen processing and presentation in human muscle: cathepsin S is critical for MHC class II expression and upregulated in inflammatory myopathies

scientific article published on May 2003

Antigen recognition properties of a Vgamma1.3Vdelta2-T-cell receptor from a rare variant of polymyositis

scientific article

Antigen-specific blockade of lethal CD8 T-cell mediated autoimmunity in a mouse model of multiple sclerosis

scientific article published in May 2009

Apraxia profile differentiates behavioural variant frontotemporal from Alzheimer's dementia in mild disease stages

scientific article

Apraxia profiles-A single cognitive marker to discriminate all variants of frontotemporal lobar degeneration and Alzheimer's disease

scientific article published on 16 May 2018

Apraxia screening predicts Alzheimer pathology in frontotemporal dementia

scientific article published on 10 October 2018

Assessment of immune functions and MRI disease activity in relapsing-remitting multiple sclerosis patients switching from natalizumab to fingolimod (ToFingo-Successor).

scientific article published on 23 June 2015

Association of Intrathecal Immunoglobulin G Synthesis With Disability Worsening in Multiple Sclerosis

scientific article published on 01 July 2019

Association of smoking but not HLA-DRB1*15:01, APOE or body mass index with brain atrophy in early multiple sclerosis.

scientific article published in March 2018

Aucune différence significative du taux de poussée chez les patients passant au natalizumab administré une fois toutes les 6 semaines ou restant sous natalizumab administré une fois toutes les 4 semaines : analyse d’efficacité comparative de l’étude

scientific article published on 01 September 2020

Author Correction: Immune reconstitution therapies: concepts for durable remission in multiple sclerosis

scientific article published on 01 February 2020

Author Correction: Neurological immunotherapy in the era of COVID-19 - looking for consensus in the literature

scientific article published on 22 July 2020

Author response: Prospective validation of the PML risk biomarker l-selectin and influence of natalizumab extended intervals

scientific article published on 01 September 2020

Auto-SCT in severe paraproteinemic neuropathy

scientific article published on 31 May 2010

Autoimmunity complicating SARS-CoV-2 infection in selective IgA-deficiency

scientific article published on 12 August 2020

B7-H1 Selectively Controls TH17 Differentiation and Central Nervous System Autoimmunity via a Novel Non-PD-1-Mediated Pathway

scientific article published on 16 September 2015

B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of multiple sclerosis

scientific article published in June 2008

B7-H1 shapes T-cell-mediated brain endothelial cell dysfunction and regional encephalitogenicity in spontaneous CNS autoimmunity

scientific article published on 26 September 2016

B7-H1-deficiency enhances the potential of tolerogenic dendritic cells by activating CD1d-restricted type II NKT cells

scientific article

Basic and escalating immunomodulatory treatments in multiple sclerosis: current therapeutic recommendations

scientific article published on 29 October 2008

Benefit-Risk Profile of Sphingosine-1-Phosphate Receptor Modulators in Relapsing and Secondary Progressive Multiple Sclerosis

scientific article published on 13 September 2017

Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus

scholarly article by Johanna Breuer et al published 22 August 2018 in Journal of Neuroinflammation

Blockade of PD-L1 (B7-H1) augments human tumor-specific T cell responses in vitro

article

Blockade of the kinin receptor B1 protects from autoimmune CNS disease by reducing leukocyte trafficking

scientific article published on 8 January 2011

Blocking of α4 integrin does not protect from acute ischemic stroke in mice

scientific article published on 17 April 2014

Blood and cerebrospinal fluid immune cell profiles in patients with temporal lobe epilepsy of different etiologies

scientific article published on 07 September 2020

Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells

scientific article published on 18 May 2016

Broad spectrum antibiotics in bile duct diseases

scientific article

CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke.

scientific article published on 15 October 2014

CD3-positive B cells: a storage-dependent phenomenon

scientific article

CD34+ progenitor cells mobilized by natalizumab are not a relevant reservoir for JC virus

scientific article published on 15 November 2010

CD4(+) CD25(+) FoxP3(+) regulatory T cells suppress cytotoxicity of CD8(+) effector T cells: implications for their capacity to limit inflammatory central nervous system damage at the parenchymal level.

scientific article published on 28 February 2012

CD4(+) T cells predominate in cerebrospinal fluid and leptomeningeal and parenchymal infiltrates in cerebral amyloid β-related angiitis

scientific article published on 01 June 2012

CD4(+)HLA-G(+) regulatory T cells: Molecular signature and pathophysiological relevance

scientific article published on 27 January 2016

CD4+ T effector memory cell dysfunction is associated with the accumulation of granulocytic myeloid-derived suppressor cells in glioblastoma patients

scientific article published on 17 November 2015

CD4+NKG2D+ T cells exhibit enhanced migratory and encephalitogenic properties in neuroinflammation.

scientific article

CD62L is not a reliable biomarker for predicting PML risk in natalizumab-treated R-MS patients

scientific article

CD62L test at 2 years of natalizumab predicts progressive multifocal leukoencephalopathy

scientific article

CD8(+) T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing.

scientific article

CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome

scientific article published on 18 December 2019

CD8+ T cells and neuronal damage: direct and collateral mechanisms of cytotoxicity and impaired electrical excitability

scientific article published on 30 June 2009

CD8+ T-cell clones dominate brain infiltrates in Rasmussen encephalitis and persist in the periphery

scientific article published on 29 January 2009

CD8+ T-cell immunity in chronic inflammatory demyelinating polyradiculoneuropathy

scientific article published on 11 January 2012

CNS inflammation and neuronal degeneration is aggravated by impaired CD200-CD200R-mediated macrophage silencing

scientific article published on 01 February 2008

CON: Regulatory T Cells Are Protective in Ischemic Stroke ⬇️

scientific article published on 02 July 2013

COVID-19-associated risks and effects in myasthenia gravis (CARE-MG)

scientific article published on 01 December 2020

CT versus MR Techniques in the Detection of Cervical Artery Dissection

scientific article published on 2 June 2017

Can cognitive assessment really discriminate early stages of Alzheimer's and behavioural variant frontotemporal dementia at initial clinical presentation?

scientific article published on 09 August 2017

Can immune reprogramming with alemtuzumab induce permanent remission in multiple sclerosis?

scientific article published on 23 August 2017

Can we predict cognitive decline after initial diagnosis of multiple sclerosis? Results from the German National early MS cohort (KKNMS).

scientific article published on 4 December 2018

Case Report: A Spinal Ischemic Lesion in a 24-Year-Old Patient With Fabry Disease

scientific article published on 14 December 2020

Case report of bilateral relapsing-remitting sciatic nerve palsy during two pregnancies

scientific article

Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes

scientific article

Cerebrospinal Fluid Concentrations of Neuronal Proteins Are Reduced in Primary Angiitis of the Central Nervous System.

scientific article published on 5 June 2018

Cerebrospinal fluid analysis in 108 patients with progressive multifocal leukoencephalopathy

scientific article published on 27 October 2020

Circulating lymphocyte levels and relationship with infection status in patients with relapsing-remitting multiple sclerosis treated with daclizumab beta

scientific article published on September 2017

Cladribine - an old newcomer for pulsed immune reconstitution in MS.

scientific article published on 8 September 2017

Classification of neurological diseases using multi-dimensional CSF analysis

publication published on 01 October 2021

Clinical effects of natalizumab on multiple sclerosis appear early in treatment course

scientific article published on 5 January 2013

Clinical experiences with postoperative electromagnetic stimulation of pseudarthroses

scientific article published on 01 December 1982

Clinical features, pathogenesis, and treatment of myasthenia gravis: a supplement to the Guidelines of the German Neurological Society

scientific article

Clinical implications of serum neurofilament in newly diagnosed MS patients: A longitudinal multicentre cohort study

scientific article published on 24 May 2020

Clinical outcomes in patients who discontinue natalizumab therapy after 2 years in the Tysabri® Observational Program (TOP)

scientific article published on 14 May 2020

Clinical relevance of brain volume measures in multiple sclerosis

scientific article

Clinical relevance of specific T-cell activation in the blood and cerebrospinal fluid of patients with mild Alzheimer's disease.

scientific article published on 23 August 2014

Clinically relevant interaction of rivaroxaban and valproic acid - A case report

scientific article published on 01 June 2020

Clonal expansions of pathogenic CD8+ effector cells in the CNS of myelin mutant mice

scientific article published on 15 August 2007

Collateral bystander damage by myelin-directed CD8+ T cells causes axonal loss

scientific article

Collateral neuronal apoptosis in CNS gray matter during an oligodendrocyte-directed CD8(+) T cell attack.

scientific article published in March 2010

Comment on "Functional consequences of Kv1.3 ion channel rearrangement into the immunological synapse"

scientific article published on 10 July 2009

Comparative efficacy of first-line natalizumab vs IFN-β or glatiramer acetate in relapsing MS.

scientific article published on April 2016

Comparative efficacy of switching to natalizumab in active multiple sclerosis

scientific article

Comparing Plasma Exchange to Escalated Methyl Prednisolone in Refractory Multiple Sclerosis Relapses

scientific article published on 22 December 2019

Complete Epstein-Barr virus seropositivity in a large cohort of patients with early multiple sclerosis

scientific article published on 05 May 2020

Computed tomography-based quantification of lesion water uptake identifies patients within 4.5 hours of stroke onset: A multicenter observational study

scientific article published on December 2016

Concentric Sclerosis Baló: A rare Variant of Multiple Sclerosis

scientific article published on 3 April 2013

Consistent efficacy of daclizumab beta across patient demographic and disease activity subgroups in patients with relapsing-remitting multiple sclerosis

scientific article published on 19 June 2017

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

scientific article published on 18 January 2020

Correction: A β-Lactam Antibiotic Dampens Excitotoxic Inflammatory CNS Damage in a Mouse Model of Multiple Sclerosis

Correction: A β-Lactam Antibiotic Dampens Excitotoxic Inflammatory CNS Damage in a Mouse Model of Multiple Sclerosis.

scientific article

Correction: CD4+NKG2D+ T Cells Exhibit Enhanced Migratory and Encephalitogenic Properties in Neuroinflammation.

scientific article published on 20 December 2013

Correction: Effects of Natalizumab Treatment on Foxp3+ T Regulatory Cells.

scientific article

Correction: Kinetics of IL-6 Production Defines T Effector Cell Responsiveness to Regulatory T Cells in Multiple Sclerosis.

scientific article

Correction: PD-1 Regulates Neural Damage in Oligodendroglia-Induced Inflammation.

scientific article

Correction: Two pore domain potassium channels in cerebral ischemia: a focus on K2P9.1 (TASK3, KCNK9).

scientific article

Cortex Parcellation Associated Whole White Matter Parcellation in Individual Subjects

scientific article published on 06 July 2017

Covarying patterns of white matter lesions and cortical atrophy predict progression in early MS

scientific article published on 05 February 2020

Current aspects of therapy conversion for multiple sclerosis

scientific article published in October 2015

Current status on B-cell depletion therapy in autoimmune diseases other than rheumatoid arthritis

scientific article published on 27 August 2009

Cytoplasmic translocation of Olig2 in adult glial progenitors marks the generation of reactive astrocytes following autoimmune inflammation

scientific article published on 30 June 2006

Cytosolic RIG-I-like helicases act as negative regulators of sterile inflammation in the CNS.

scientific article published on 4 December 2011

Cytotoxic CD8+ T cell-neuron interactions: perforin-dependent electrical silencing precedes but is not causally linked to neuronal cell death

scientific article published in December 2009

Cytotoxic CD8+ T cells and CD138+ plasma cells prevail in cerebrospinal fluid in non-paraneoplastic cerebellar ataxia with contactin-associated protein-2 antibodies.

scientific article

DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis.

scientific article

DTI detects water diffusion abnormalities in the thalamus that correlate with an extremity pain episode in a patient with multiple sclerosis

scientific article

Daclizumab HYP versus Interferon Beta-1a in Relapsing Multiple Sclerosis

scientific article published on October 2015

Death receptor-mediated apoptosis in human malignant glioma cells: modulation by the CD40/CD40L system

scientific article

DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning

scientific article published on 03 February 2020

Defective synaptic transmission causes disease signs in a mouse model of juvenile neuronal ceroid lipofuscinosis.

scientific article published on 14 November 2017

Deficiency of the negative immune regulator B7-H1 enhances inflammation and neuropathic pain after chronic constriction injury of mouse sciatic nerve

scientific article published on 4 January 2010

Defining mechanisms of neural plasticity after brainstem ischemia in rats

scientific article published on 11 May 2018

Defining response profiles after alemtuzumab: Rare paradoxical disease exacerbation

scientific article published on 19 January 2018

Dementia Apraxia Test (DATE): A Brief Tool to Differentiate Behavioral Variant Frontotemporal Dementia from Alzheimer's Dementia Based on Apraxia Profiles

scientific article published on 19 October 2015

Dementia as a primary symptom in late onset multiple sclerosis. Case series and review of the literature

scientific article published in June 2005

Dendritic Cells Ameliorate Autoimmunity in the CNS by Controlling the Homeostasis of PD-1 Receptor+ Regulatory T Cells

scientific article published on 16 August 2012

Dendritic cell vaccination in autoimmune disease ⬇️

scientific article published on March 1, 2013

Destruction of neurons by cytotoxic T cells: a new pathogenic mechanism in Rasmussen's encephalitis

scientific article

Detecting myositis as a cause of unexplained dysphagia: Proposal for a diagnostic algorithm

scientific article published in 2021

Detrimental contribution of the immuno-inhibitor B7-H1 to rabies virus encephalitis.

scientific article

Diagnostic criteria for Susac syndrome

scientific article

Diagnostik der Multiplen Sklerose 2010 Revision der McDonald-Kriterien

scientific article published on 01 October 2011

Dichoptic Metacontrast Masking Functions to Infer Transmission Delay in Optic Neuritis

scientific article

Dietary salt promotes ischemic brain injury and is associated with parenchymal migrasome formation

scientific article published in PLoS ONE

Diffusion abnormality in Balo's concentric sclerosis: clues for the pathogenesis

scientific article published on 01 January 2005

Dimethyl fumarate treatment alters circulating T helper cell subsets in multiple sclerosis

scientific article

Discriminative power of intra-retinal layers in early multiple sclerosis using 3D OCT imaging

scientific article published on 02 August 2018

Disease-modifying therapies in multiple sclerosis: an update on recent and ongoing trials and future strategies

scientific article

Disease-modifying treatments and cognition in relapsing-remitting multiple sclerosis: A meta-analysis

scientific article published on 19 May 2020

Distinct cognitive impairments in different disease courses of multiple sclerosis-A systematic review and meta-analysis

scientific article

Distinct pattern of lesion distribution in multiple sclerosis is associated with different circulating T-helper and helper-like innate lymphoid cell subsets.

scientific article

Does Device Selection Impact Recanalization Rate and Neurological Outcome?: An Analysis of the Save ChildS Study

scientific article published on 02 March 2020

Does the environment influence multiple sclerosis pathogenesis via UVB light and/or induction of vitamin D?

scientific article published on 18 May 2018

Dose-dependent melanonychia by mitoxantrone.

scientific article published in July 2009

Dual action by fumaric acid esters synergistically reduces adhesion to human endothelium

scientific article

Dysphagia in NMOSD and MOGAD as a surrogate of brain involvement?

scientific article published on 18 December 2020

ECTRIMS/EAN Guideline on the pharmacological treatment of people with multiple sclerosis

scientific article

ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis.

scientific article published on 19 January 2018

EMR-integrated minimal core dataset for routine health care and multiple research settings: A case study for neuroinflammatory demyelinating diseases

scientific article published on 15 October 2019

Early and Degressive Putamen Atrophy in Multiple Sclerosis.

scientific article

Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation

scientific article published on 9 March 2010

Early effective treatment may protect from cognitive decline in paediatric multiple sclerosis

scientific article published on 05 September 2019

Early silent microstructural degeneration and atrophy of the thalamocortical network in multiple sclerosis

scientific article

Eculizumab versus rituximab in generalised myasthenia gravis

scientific article published on 04 March 2022

Effects of blood transportation on human peripheral mononuclear cell yield, phenotype and function: implications for immune cell biobanking.

scientific article

Effects of glatiramer acetate in a spontaneous model of autoimmune neuroinflammation

scientific article published on 09 May 2014

Effects of natalizumab treatment on Foxp3+ T regulatory cells

scientific article

Efficacy and safety of alemtuzumab versus fingolimod in RRMS after natalizumab cessation

scientific article published on 16 November 2018

Efficacy and safety of natalizumab in multiple sclerosis: interim observational programme results.

scientific article

Efficacy of alemtuzumab in relapsing-remitting MS patients who received additional courses after the initial two courses: Pooled analysis of the CARE-MS, extension, and TOPAZ studies

scientific article published on 25 November 2019

Efficacy of alemtuzumab over 6 years in relapsing-remitting multiple sclerosis patients who relapsed between courses 1 and 2: Post hoc analysis of the CARE-MS studies

scientific article published on 01 November 2019

Efficacy of daclizumab beta versus intramuscular interferon beta-1a on disability progression across patient demographic and disease activity subgroups in DECIDE.

scientific article

Electronic volume analysis of cell nuclei in the gastric mucosa

scientific article published on 01 January 1975

Endothelial Basement Membrane Laminin 511 Contributes to Endothelial Junctional Tightness and Thereby Inhibits Leukocyte Transmigration.

scientific article

Endothelial TWIK-related potassium channel-1 (TREK1) regulates immune-cell trafficking into the CNS.

scientific article

Epoch Analysis of On-Treatment Disability Progression Events over Time in the Tysabri Observational Program (TOP)

scientific article published on 15 January 2016

Escalating immunotherapy of multiple sclerosis--new aspects and practical application.

scientific article

Evaluation of soluble HLA-G as a biomarker for multiple sclerosis

scientific article published on 27 July 2011

Evans syndrome associated with sterile inflammation of the central nervous system: a case report

scientific article

Evidence for early, non-lesional cerebellar damage in patients with multiple sclerosis: DTI measures correlate with disability, atrophy, and disease duration

scientific article

Evidence of a pathogenic role for CD8(+) T cells in anti-GABAB receptor limbic encephalitis.

scientific article

Excitotoxic neuronal cell death during an oligodendrocyte-directed CD8+ T cell attack in the CNS gray matter

scientific article published on 5 October 2013

Expert opinion on the use of cladribine tablets in clinical practice

scientific article published on 24 June 2020

Express and protect yourself: the potential role of HLA-G on muscle cells and in inflammatory myopathies

scientific article (publication date: November 2003)

Expression of CD28-related costimulatory molecule and its ligand in inflammatory neuropathies

scientific article published on 01 January 2007

Expression of K2P5.1 potassium channels on CD4+ T lymphocytes correlates with disease activity in rheumatoid arthritis patients

scientific article published on 11 February 2011

Expression of antigen processing and presenting molecules by Schwann cells in inflammatory neuropathies

scientific article

Expression of the B7-related molecule B7-H1 by glioma cells: a potential mechanism of immune paralysis

scientific article published on November 2003

Expression of the B7-related molecule ICOSL by human glioma cells in vitro and in vivo

scientific article (publication date: December 2003)

Expression of the immune-tolerogenic major histocompatibility molecule HLA-G in multiple sclerosis: implications for CNS immunity

scientific article published on 25 August 2005

Expression of toll-like receptors by human muscle cells in vitro and in vivo: TLR3 is highly expressed in inflammatory and HIV myopathies, mediates IL-8 release and up-regulation of NKG2D-ligands.

scientific article published on 17 November 2005

FOXP3+ T regulatory cells in idiopathic inflammatory myopathies

scientific article published in August 2010

FTY720 (fingolimod) treatment tips the balance towards less immunogenic antigen-presenting cells in patients with multiple sclerosis.

scientific article published on 2 March 2015

Facing the challenges of chronic pruritus: a report from a multi-disciplinary medical itch centre in Germany

scientific article published in March 2015

Failed, Interrupted, or Inconclusive Trials on Immunomodulatory Treatment Strategies in Multiple Sclerosis: Update 2015-2020

scientific article published on 12 August 2020

Failed, interrupted and inconclusive trials on relapsing multiple sclerosis treatment: update 2010-2015.

scientific article published on 8 April 2016

Feasibility, Safety, and Outcome of Endovascular Recanalization in Childhood Stroke: The Save ChildS Study

scientific article published on 14 October 2019

Fiberglass bandage in bone and soft-tissue injuries

scientific article published on 01 February 1975

Fine-tuning of regulatory T cell function: the role of calcium signals and naive regulatory T cells for regulatory T cell deficiency in multiple sclerosis

scientific article published on 10 April 2013

Fingolimod does not impair T-cell release from the thymus and beneficially affects Treg function in patients with multiple sclerosis

scientific article published on 12 January 2015

Fingolimod treatment promotes regulatory phenotype and function of B cells

scientific article published on 16 January 2015

FoxP3+ regulatory T cells determine disease severity in rodent models of inflammatory neuropathies

scientific article

Frequency of regulatory T cells is not affected by transient B cell depletion using anti-CD20 antibodies in rheumatoid arthritis

scientific article published on 3 December 2008

From the background to the spotlight: TASK channels in pathological conditions.

scientific article

Fulfilling the dream: tolerogenic dendritic cells to treat multiple sclerosis ⬇️

scientific article published on 01 March 2012

Fulminant MS Reactivation Following Combined Fingolimod Cessation and Yellow Fever Vaccination

scientific article published on 28 November 2019

Functional energetics of CD4+-cellular immunity in monoclonal antibody-associated progressive multifocal leukoencephalopathy in autoimmune disorders

scientific article (publication date: 20 April 2011)

Fundamental mechanistic insights from rare but paradigmatic neuroimmunological diseases ⬇️

journal article from 'Nature Reviews Neurology' published in 2021

Gaps Between Aims and Achievements in Therapeutic Modification of Neuronal Damage ("Neuroprotection").

scientific article published on April 2015

Generating microglia from human pluripotent stem cells: novel in vitro models for the study of neurodegeneration

scientific article published on 19 December 2019

Generation of a Model to Predict Differentiation and Migration of Lymphocyte Subsets under Homeostatic and CNS Autoinflammatory Conditions

scientific article published on 17 March 2020

Genetic determinants of the humoral immune response in MS

scientific article published on 16 July 2020

Glatiramer acetate attenuates pro-inflammatory T cell responses but does not directly protect neurons from inflammatory cell death

scientific article

GluR3 antibodies: prevalence in focal epilepsy but no specificity for Rasmussen's encephalitis.

scientific article published in October 2001

Greater sensitivity to multiple sclerosis disability worsening and progression events using a roving versus a fixed reference value in a prospective cohort study

scientific article published on May 2017

Guidance for the management of myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) during the COVID-19 pandemic

scientific article published on 25 March 2020

Guidelines on dermatomyositis--excerpt from the interdisciplinary S2k guidelines on myositis syndromes by the German Society of Neurology

scientific article published in March 2016

Gut-CNS-Axis as Possibility to Modulate Inflammatory Disease Activity-Implications for Multiple Sclerosis

scientific article

HLA-G 2012 conference: the 15-year milestone update

scientific article published on 24 January 2013

HLA-G expression defines a novel regulatory T-cell subset present in human peripheral blood and sites of inflammation.

scientific article published on 19 March 2007

HLA-G in the nervous system

scientific article published on 8 December 2006

Hide-and-seek in the brain: a role for HLA-G mediating immune privilege for glioma cells

scientific article published on October 2003

High anti-JCPyV serum titers coincide with high CSF cell counts in RRMS patients

scientific article published on 05 November 2020

Highlights from the 2019 European Congress on Treatment and Research in Multiple Sclerosis (ECTRIMS 2019)

scientific article published on 04 May 2020

Highlights from the 31st ECTRIMS congress - Barcelona 2015

scientific article published on 01 January 2016

Highly reactive anti-myelin oligodendrocyte glycoprotein antibodies differentiate demyelinating diseases from viral encephalitis in children

scientific article published on 22 December 2010

Human CCR5high effector memory cells perform CNS parenchymal immune surveillance via GZMK-mediated transendothelial diapedesis

scientific article published on 01 November 2019

Human CD4+ HLA-G+ regulatory T cells are potent suppressors of graft-versus-host disease in vivo.

scientific article published on 17 April 2014

Human herpesvirus 6 in serum and spinal fluid of patients with multiple sclerosis?

scientific article

Human muscle cells express a B7-related molecule, B7-H1, with strong negative immune regulatory potential: a novel mechanism of counterbalancing the immune attack in idiopathic inflammatory myopathies

scientific article

Human muscle cells express the costimulatory molecule B7-H3, which modulates muscle-immune interactions

scholarly article by Anne Waschbisch et al published November 2008 in Arthritis and Rheumatism

Human myoblasts modulate the function of antigen-presenting cells

article published in 2008

Hyponatremia upon presentation to the emergency department - the need for urgent neuroimaging studies.

scientific article

IL-17 silencing does not protect nonobese diabetic mice from autoimmune diabetes

scientific article published on 23 November 2011

Iatrogenic immunosuppression with biologics in MS: expecting the unexpected?

scientific article published on 23 September 2009

Identification of inflammatory neuronal injury and prevention of neuronal damage in multiple sclerosis: hope for novel therapies?

scientific article published on December 2013

Identification of targets and new developments in the treatment of multiple sclerosis--focus on cladribine

scientific article

Identification of two-pore domain potassium channels as potent modulators of osmotic volume regulation in human T lymphocytes

scientific article published on 3 October 2012

Idiopathic inflammatory myopathies: current and future therapeutic options.

scientific article published on October 2008

Imaging matrix metalloproteinase activity in multiple sclerosis as a specific marker of leukocyte penetration of the blood-brain barrier.

scientific article published in November 2016

Immune Cell Activation in the Cerebrospinal Fluid of Patients With Parkinson's Disease

scientific article published on 18 December 2018

Immune Cell Profiling During Switching from Natalizumab to Fingolimod Reveals Differential Effects on Systemic Immune-Regulatory Networks and on Trafficking of Non-T Cell Populations into the Cerebrospinal Fluid-Results from the ToFingo Successor St

scientific article published on 9 July 2018

Immune Cell Profiling of the Cerebrospinal Fluid Provides Pathogenetic Insights Into Inflammatory Neuropathies

scientific article published on 21 March 2019

Immune cell profiling in the cerebrospinal fluid of patients with primary angiitis of the central nervous system reflects the heterogeneity of the disease

scientific article published on 07 June 2018

Immune cells contribute to myelin degeneration and axonopathic changes in mice overexpressing proteolipid protein in oligodendrocytes

scientific article published on 01 August 2006

Immune circuitry in the peripheral nervous system

scientific article published on October 2006

Immune mechanisms of new therapeutic strategies in multiple sclerosis-A focus on alemtuzumab

scientific article published on 15 April 2011

Immune mechanisms of stroke.

scientific article published on June 2012

Immune reconstitution therapies: concepts for durable remission in multiple sclerosis

scientific article published on 24 October 2019

Immune signatures of prodromal multiple sclerosis in monozygotic twins

scientific article published on 17 August 2020

Immune therapy of multiple sclerosis--future strategies

scientific article published on January 2012

Immune-refractory cancers and their little helpers--an extended role for immunetolerogenic MHC molecules HLA-G and HLA-E?

scientific article published on 31 July 2007

Immunoadsorption therapy in autoimmune encephalitides

scientific article

Immunobiology of muscle: advances in understanding an immunological microenvironment

scientific article

Immunological and clinical consequences of treating a patient with natalizumab

scientific article published on 9 September 2011

Immunomodulatory treatment strategies in multiple sclerosis

scientific article published on December 2008

Immunophenotyping of cerebrospinal fluid cells by Chipcytometry.

scientific article published on 25 May 2018

Immunophenotyping of cerebrospinal fluid cells in ischaemic stroke

scientific article published on 08 February 2019

Immunophenotyping of cerebrospinal fluid cells in multiple sclerosis: in search of biomarkers

scientific article published on July 2014

Immunoregulatory factors in multiple sclerosis patients during and after pregnancy: relevance of natural killer cells

scientific article published on 06 December 2007

Immunotherapeutic approaches in MS: update on pathophysiology and emerging agents or strategies 2006.

scientific article published on March 2007

Immunotherapy of multiple sclerosis.

scientific article

Impact of FcγR variants on the response to alemtuzumab in multiple sclerosis

scientific article published on 04 November 2019

Impaired Autonomic Responses to Emotional Stimuli in Autoimmune Limbic Encephalitis

scientific article

Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation

scientific article published on 09 May 2016

Impairment of frequency-specific responses associated with altered electrical activity patterns in auditory thalamus following focal and general demyelination

scientific article published on 23 July 2018

Implications of dietary salt intake for multiple sclerosis pathogenesis

scientific article published on 07 October 2015

Increased cortical curvature reflects white matter atrophy in individual patients with early multiple sclerosis

scientific article

Increased frequency of CD4+ CD25+ regulatory T cells in the cerebrospinal fluid but not in the blood of multiple sclerosis patients.

scientific article published in March 2007

Ineffective treatment of PML with pembrolizumab: Exhausted memory T-cell subsets as a clue?

scientific article published on 09 October 2019

Infectious risk stratification in multiple sclerosis patients receiving immunotherapy

scientific article published on 24 November 2017

Initial experience with [18F]DPA-714 TSPO-PET to image inflammation in primary angiitis of the central nervous system

scientific article published on 20 January 2020

Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis

scientific article published on 14 January 2020

Intercellular exchanges of membrane fragments (trogocytosis) between human muscle cells and immune cells: a potential mechanism for the modulation of muscular immune responses

scientific article published on 9 March 2009

Interferon Beta Use and Disability Prevention in Relapsing-Remitting Multiple Sclerosis

scientific article published on 01 February 2013

Interferon beta treatment does not induce organ-specific autoantibodies in multiple sclerosis

scientific article published on 01 September 2009

Interferon-Beta Therapy of Multiple Sclerosis Patients Improves the Responsiveness of T Cells for Immune Suppression by Regulatory T Cells.

scientific article published on 17 July 2015

Interferon-beta enhances monocyte and dendritic cell expression of B7-H1 (PD-L1), a strong inhibitor of autologous T-cell activation: relevance for the immune modulatory effect in multiple sclerosis

scientific article published on 01 October 2004

Intracerebral dendritic cells critically modulate encephalitogenic versus regulatory immune responses in the CNS.

scientific article

Intubation, Tracheostomy and Decannulation in GBS-patients - does Dysphagia matter?

scientific article published on 18 December 2018

Ion channels in autoimmune neurodegeneration.

scientific article published on 14 April 2011

Is APOE ε4 associated with cognitive performance in early MS?

scientific article published on 01 May 2020

Janus head: the dual role of HLA-G in CNS immunity

scientific article

Kinetics of IL-6 production defines T effector cell responsiveness to regulatory T cells in multiple sclerosis

scientific article

L-selectin is a possible biomarker for individual PML risk in natalizumab-treated MS patients

scientific article published on 7 August 2013

Lack of evidence for a pathogenic role of T-lymphocytes in an animal model for Charcot-Marie-Tooth disease 1A.

scientific article published on 11 January 2010

Leukocyte profiles in blood and CSF distinguish neurosarcoidosis from multiple sclerosis

scientific article published on 27 January 2020

Licensing of myeloid cells promotes central nervous system autoimmunity and is controlled by peroxisome proliferator-activated receptor γ.

scientific article published on 24 March 2012

Limbic encephalitis due to GABAB and AMPA receptor antibodies: a case series.

scientific article published on 9 October 2014

Liver X receptor activation promotes differentiation of regulatory T cells

scientific article published on 19 September 2017

Localization of UDP-GlcNAc 2-epimerase/ManAc kinase (GNE) in the Golgi complex and the nucleus of mammalian cells

scientific article

Long-term effects of dalfampridine in patients with multiple sclerosis

scientific article published on 16 November 2013

Long-term efficacy of alemtuzumab in polymyositis

scientific article published on 30 December 2014

Long-term safety and effectiveness of natalizumab treatment in clinical practice: 10 years of real-world data from the Tysabri Observational Program (TOP)

scientific article published on 31 March 2020

Longitudinal prevalence and determinants of pain in multiple sclerosis: results from the German National Multiple Sclerosis Cohort study

scientific article published on 01 April 2020

Low frequency and rare coding variation contributes to multiple sclerosis risk

Lymphocyte pharmacodynamics are not associated with autoimmunity or efficacy after alemtuzumab

scientific article published on 29 October 2019

MCAM/CD146 Signaling <i>via</i> PLCγ1 Leads to Activation of β<sub>1</sub>-Integrins in Memory T-Cells Resulting in Increased Brain Infiltration

scientific article published on 14 December 2020

March 2003: a 41 -year-old female with a solitary lesion in the liver.

scientific article published in July 2003

Mechanisms underlying lesion development and lesion distribution in CNS autoimmunity

scientific article published on 25 March 2018

Melanocortin-1 receptor activation is neuroprotective in mouse models of neuroinflammatory disease.

scientific article

Microglial expression of the B7 family member B7 homolog 1 confers strong immune inhibition: implications for immune responses and autoimmunity in the CNS.

scientific article published in March 2005

Modulation of IL-2Rα with daclizumab for treatment of multiple sclerosis ⬇️

scientific article published on 04 June 2013

Modulation of T-effector function by imatinib at the level of cytokine secretion

scientific article published on 8 June 2007

Modulation of neuronal activity by the endogenous pentapeptide QYNAD.

scientific article published in November 2003

Monitoring of blood parameters under course-modified MS therapy : Substance-specific relevance and current recommendations for action

scientific article published on 29 February 2016

Monoclonal antibodies in neuroinflammatory diseases

scientific article published on 22 March 2013

Monocyte-derived HLA-G acts as a strong inhibitor of autologous CD4 T cell activation and is upregulated by interferon-beta in vitro and in vivo: rationale for the therapy of multiple sclerosis.

scientific article

Monomethylfumarate reduces in vitro migration of mononuclear cells

scientific article published on 07 February 2014

Mouse Schwann cells activate MHC class I and II restricted T-cell responses, but require external peptide processing for MHC class II presentation

article

Multiple sclerosis therapeutics: unexpected outcomes clouding undisputed successes

scientific article published on March 2009

Multiple sclerosis therapy: an update on recently finished trials

scientific article published on 15 November 2007

Multiple sclerosis: Mitoxantrone promotes differential effects on immunocompetent cells in vitro

scientific article published in November 2005

Multiple sclerosis: advances, excitements, disenchantments

scientific article

Multiple sclerosis: comparison of copolymer-1- reactive T cell lines from treated and untreated subjects reveals cytokine shift from T helper 1 to T helper 2 cells

scientific article

Multiple sclerosis: reprogramming the immune repertoire with alemtuzumab in MS.

scientific article

Murine K2P5.1 Deficiency Has No Impact on Autoimmune Neuroinflammation due to Compensatory K2P3.1- and KV1.3-Dependent Mechanisms

scientific article

Muscle fibres and cultured muscle cells express the B7.1/2-related inducible co-stimulatory molecule, ICOSL: implications for the pathogenesis of inflammatory myopathies

scientific article published in May 2003

Muscle-derived positive and negative regulators of the immune response

scientific article

Myelin oligodendrocyte glycoprotein (MOG35-55) induced experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice

scientific article

NMDAR encephalitis: passive transfer from man to mouse by a recombinant antibody

scientific article published on 3 October 2017

Natalizumab restores evoked potential abnormalities in patients with relapsing-remitting multiple sclerosis

scientific article published on 06 December 2010

Natalizumab treatment in a patient with chronic inflammatory demyelinating polyneuropathy

scientific article published on July 2010

Natalizumab treatment shows low cumulative probabilities of confirmed disability worsening to EDSS milestones in the long-term setting

scientific article published on 02 May 2018

Natalizumab-associated PML: Challenges with incidence, resulting risk, and risk stratification

scientific article

Neurochondrin is a neuronal target antigen in autoimmune cerebellar degeneration

scientific article

Neurocognitive decline in HIV patients is associated with ongoing T-cell activation in the cerebrospinal fluid.

scientific article

Neuroimmunotherapies Targeting T Cells: From Pathophysiology to Therapeutic Applications

scientific article

Neuroinflammation: the world is not enough

scientific article published on 01 June 2012

Neurological Manifestations of COVID-19 Feature T Cell Exhaustion and Dedifferentiated Monocytes in Cerebrospinal Fluid

scientific article published on 23 December 2020

Neurological immunotherapy in the era of COVID-19 - looking for consensus in the literature

scientific article published on 08 July 2020

Neuron-directed autoimmunity in the central nervous system: entities, mechanisms, diagnostic clues, and therapeutic options

scientific article published on June 2012

Neurons as targets for T cells in the nervous system.

scientific article published on 13 March 2013

New evidence for teriflunomide in multiple sclerosis

scientific article published on 23 January 2014

Next-Generation Neuroimmunology: New Technologies to Understand Central Nervous System Autoimmunity

scientific article published on 05 March 2020

No effect of immunomodulatory therapy in focal epilepsy with positive glutamate receptor type 3--antibodies

scientific article published on 18 April 2006

Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation

scientific article published on 17 June 2016

Novel pathomechanisms in inflammatory neuropathies

scientific article published on 28 November 2017

Nrf2 and beyond: deciphering the mode of action of fumarates in the inflamed central nervous system

scientific article

Nucleotide metabolizing ectoenzymes are upregulated in A431 cells periodically treated with cytostatic ATP leading to partial resistance without preventing apoptosis ⬇️

scientific article published on September 16, 1998

Nur77 serves as a molecular brake of the metabolic switch during T cell activation to restrict autoimmunity

scientific article published on 02 August 2018

O6.04GRANULOCYTIC MYELOID-DERIVED CELLS OBTAINED FROM BLOOD MAINLY SUPPRESS T-CELL PROLIFERATION IN PATIENTS WITH GLIOBLASTOMA.

scientific article published in September 2014

Ocrelizumab initiation in patients with MS: A multicenter observational study

scientific article published on 09 April 2020

Ofatumumab versus Teriflunomide in Multiple Sclerosis

scientific article published on 01 August 2020

On tissue extracts inactivating oxytocin

scientific article published on 01 October 1962

Onconeural antigen spreading in paraneoplastic neurological disease due to small cell lung cancer.

scientific article published on 9 July 2018

Optimizing therapy early in multiple sclerosis: An evidence-based view

scientific article

Oral disease-modifying treatments for multiple sclerosis: the story so far.

scientific article published on January 2007

PD-1 regulates neural damage in oligodendroglia-induced inflammation

scientific article

PML risk stratification using anti-JCV antibody index and L-selectin.

scientific article published on 2 October 2015

Paraneoplastic and non-paraneoplastic autoimmunity to neurons in the central nervous system

scientific article published on 15 September 2012

Pathology of immune reconstitution inflammatory syndrome in multiple sclerosis with natalizumab-associated progressive multifocal leukoencephalopathy

scientific article published on 6 November 2011

Patients with a relapsing course of SREAT exhibit persistent intrathecal CD4+ T cell activation

scientific article published on 23 November 2020

Pharmacological Approaches to Delaying Disability Progression in Patients with Multiple Sclerosis

scientific article

Pharmacological treatment of early multiple sclerosis

scientific article published on January 2008

Phospholipase D1 mediates lymphocyte adhesion and migration in experimental autoimmune encephalomyelitis

scientific article published on 5 June 2014

Plasma kallikrein modulates immune cell trafficking during neuroinflammation via PAR2 and bradykinin release

scientific article published on 17 December 2018

Post-intervention status in patients with refractory myasthenia gravis treated with eculizumab during REGAIN and its open-label extension

scientific article published on 23 November 2020

Postpartum disease activity and breastfeeding in multiple sclerosis revisited

scientific article published in August 2010

Postpartum-activation of multiple sclerosis is associated with down-regulation of tolerogenic HLA-G

scientific article published on 11 June 2007

Pretreatment anti-thyroid autoantibodies indicate increased risk for thyroid autoimmunity secondary to alemtuzumab: A prospective cohort study

scientific article published on 29 July 2019

Primary B Cell Lymphoma of the CNS Mimicking Anti-LGI1 Limbic Encephalitis

scientific article published on 10 August 2018

Primary angiitis of the central nervous system: diagnosis and treatment

scientific article published on 09 July 2018

Programmed cell death-1 deficiency exacerbates T cell activation and atherogenesis despite expansion of regulatory T cells in atherosclerosis-prone mice

scientific article

Prominent T-Cell Responses against the Acetylcholine Receptor Subunit in Myasthenia Gravis

article

Prospective validation of the PML risk biomarker l-selectin and influence of natalizumab extended intervals

scientific article published on 22 August 2019

Protective potential of dimethyl fumarate in a mouse model of thalamocortical demyelination

scientific article published on 09 May 2018

Prothrombin and factor X are elevated in multiple sclerosis patients.

scientific article published on 24 October 2016

Randomized study of teriflunomide effects on immune responses to neoantigen and recall antigens

scientific article

Rapidly progressive B-cell dominated inflammatory neuropathy and littoral cell angioma of the spleen associated with plasmablastic B-cell lymphoma

scientific article published on 03 January 2012

Rasmussen encephalitis treated with natalizumab.

scientific article published on 21 June 2013

Rasmussen encephalitis with active inflammation and delayed seizures onset.

scientific article published in March 2004

Real-world disability improvement in patients with relapsing-remitting multiple sclerosis treated with natalizumab in the Tysabri Observational Program

scientific article published on 24 June 2020

Recent clinical trials and future therapies

scientific article published on December 2008

Recovery of thalamic microstructural damage after Shiga toxin 2-associated hemolytic-uremic syndrome

scientific article

Redefining the heterogeneity of peripheral nerve cells in health and autoimmunity

scientific article published on 15 April 2020

Reduced cortisol levels in cerebrospinal fluid and differential distribution of 11beta-hydroxysteroid dehydrogenases in multiple sclerosis: implications for lesion pathogenesis

scientific article published on 10 April 2010

Regulatory Functions of Natural Killer Cells in Multiple Sclerosis.

scientific article published on 19 December 2016

Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature

scientific article published on 15 November 2012

Regulatory T cells exhibit enhanced migratory characteristics, a feature impaired in patients with multiple sclerosis

scientific article published on 01 December 2010

Relevance of raised cerebrospinal fluid monocyte levels in patients with frontotemporal dementia.

scientific article published on 13 October 2017

Reply to Liu et al.: Haplotype matters: CD226 polymorphism as a potential trigger for impaired immune regulation in multiple sclerosis

scientific article published on 30 January 2017

Resolving the cognitive clinico-radiological paradox - Microstructural degeneration of fronto-striatal-thalamic loops in early active multiple sclerosis

scientific article published on 26 September 2019

Response to eculizumab in patients with myasthenia gravis recently treated with chronic IVIg: a subgroup analysis of REGAIN and its open-label extension study

scientific article published on 06 May 2020

Response to letter regarding article, "blocking of α4 integrin does not protect from acute ischemic stroke in mice".

scientific article published on 24 July 2014

Risikostratifizierung einer progressiven multifokalen Leukenzephalopathie unter Natalizumab

scientific article published on 01 October 2011

Risks and benefits of multiple sclerosis therapies: need for continual assessment?

scientific article published on 01 June 2011

Risks and risk management in modern multiple sclerosis immunotherapeutic treatment

scientific article published on 01 April 2019

Rivaroxaban ameliorates disease course in an animal model of multiple sclerosis.

scientific article

Safety and clinical outcomes of rituximab therapy in patients with different autoimmune diseases: experience from a national registry (GRAID).

scientific article published on 13 May 2011

Seizures and epilepsy in multiple sclerosis: epidemiology and prognosis in a large tertiary referral center

scientific article published on 08 May 2019

Serial position effects rapidly distinguish Alzheimer's from frontotemporal dementia

scientific article published on 05 December 2019

Sex bias in MHC I-associated shaping of the adaptive immune system.

scientific article published on 12 February 2018

Shared neural correlates of limb apraxia in early stages of Alzheimer's dementia and behavioural variant frontotemporal dementia

scientific article published on 26 August 2016

Signatures of immune reprogramming in anti-CD52 therapy of MS: markers for risk stratification and treatment response

scientific article published on 13 December 2019

Simultaneous early-onset immune thrombocytopenia and autoimmune thyroid disease following alemtuzumab treatment in relapsing-remitting multiple sclerosis

scientific article

Skeletal muscle cells actively shape (auto)immune responses

scientific article published on 8 March 2018

Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis

scientific article published on 30 March 2010

Sodium chloride promotes pro-inflammatory macrophage polarization thereby aggravating CNS autoimmunity.

scientific article

Specific aspects of modern life for people with multiple sclerosis: considerations for the practitioner

scientific article published on March 2014

Specific central nervous system recruitment of HLA-G(+) regulatory T cells in multiple sclerosis

scientific article

Specific loss of cellular L-selectin on CD4(+) T cells is associated with progressive multifocal leukoencephalopathy development during HIV infection.

scientific article published on March 2014

Stromal interaction molecules 1 and 2 are key regulators of autoreactive T cell activation in murine autoimmune central nervous system inflammation

scientific article

Substance P Saliva Reduction Predicts Pharyngeal Dysphagia in Parkinson's Disease

scholarly article by Jens Burchard Schröder et al published 2019 in Frontiers in Neurology

Successful Replication of GWAS Hits for Multiple Sclerosis in 10,000 Germans Using the Exome Array

scientific article published on 26 October 2015

Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity

scientific article published on 01 January 2021

Switching from natalizumab to fingolimod: A randomized, placebo-controlled study in RRMS

scientific article published on 29 May 2015

Symptomatic therapy in multiple sclerosis: a review for a multimodal approach in clinical practice

scientific article

T cell suppression by naturally occurring HLA-G-expressing regulatory CD4+ T cells is IL-10-dependent and reversible

scientific article published on 28 April 2009

TASK1 modulates inflammation and neurodegeneration in autoimmune inflammation of the central nervous system

scientific article

TRPM2 cation channels modulate T cell effector functions and contribute to autoimmune CNS inflammation

scientific article

TSPO imaging-guided characterization of the immunosuppressive myeloid tumor microenvironment in patients with malignant glioma

scientific article published on 12 February 2020

TWIK-related acid-sensitive K+ channel 1 (TASK1) and TASK3 critically influence T lymphocyte effector functions

scientific article published on 28 March 2008

Targeting B cells in relapsing-remitting multiple sclerosis: from pathophysiology to optimal clinical management.

scientific article

Targeting Different Monocyte/Macrophage Subsets Has No Impact on Outcome in Experimental Stroke

scientific article published on 14 March 2017

Targeting Ewing sarcoma with activated and GD2-specific chimeric antigen receptor-engineered human NK cells induces upregulation of immune-inhibitory HLA-G.

scientific article published on 28 October 2016

Targeting Voltage-Dependent Calcium Channels with Pregabalin Exerts a Direct Neuroprotective Effect in an Animal Model of Multiple Sclerosis

scientific article published on 27 November 2018

Temporal pattern of ICAM-I mediated regulatory T cell recruitment to sites of inflammation in adoptive transfer model of multiple sclerosis

scientific article

Teriflunomide and its mechanism of action in multiple sclerosis

scientific article published on April 2014

Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects

scientific article published on 01 May 2019

Thalamic involvement in patients with neurologic impairment due to Shiga toxin 2.

scientific article published on 19 February 2013

The Agony of Choice? Preserved Affective Decision Making in Early Multiple Sclerosis

scientific article published on 02 September 2020

The CD28 related molecule ICOS: T cell modulation in the presence and absence of B7.1/2 and regulational expression in multiple sclerosis

scientific article published on 01 July 2003

The Coagulation Factors Fibrinogen, Thrombin, and Factor XII in Inflammatory Disorders-A Systematic Review

scientific article published on 26 July 2018

The Impact of Dysphagia in Myositis: A Systematic Review and Meta-Analysis

scientific article published on 08 July 2020

The NKG2D-IL-15 signaling pathway contributes to T-cell mediated pathology in inflammatory myopathies

scientific article published on 4 December 2015

The STING-IFN-β-Dependent Axis Is Markedly Low in Patients with Relapsing-Remitting Multiple Sclerosis

scientific article published on 04 December 2020

The TASK1 channel inhibitor A293 shows efficacy in a mouse model of multiple sclerosis

scientific article published on 27 August 2012

The cell-specific expression of metalloproteinase-disintegrins (ADAMs) in inflammatory myopathies

scientific article published on 03 January 2007

The co-inhibitory molecule PD-1 modulates disease severity in a model for an inherited, demyelinating neuropathy

scientific article published on 15 October 2008

The contribution of TWIK-related acid-sensitive K+-containing channels to the function of dorsal lateral geniculate thalamocortical relay neurons.

scientific article published on 19 January 2006

The farnesoid-X-receptor in myeloid cells controls CNS autoimmunity in an IL-10-dependent fashion

scientific article published on 6 July 2016

The future of multiple sclerosis therapy

scientific article

The genetic influence of the nonclassical MHC molecule HLA-G on multiple sclerosis

scientific article published on 15 February 2007

The humoral response in the pathogenesis of gluten ataxia

scientific article published on 01 April 2003

The impact of lesion location on dysphagia incidence, pattern and complications in acute stroke. Part 1: dysphagia incidence, severity and aspiration

scientific article published on 13 February 2015

The impact of lesion location on dysphagia incidence, pattern and complications in acute stroke. Part 2: Oropharyngeal residue, swallow and cough response, and pneumonia.

scientific article published on 27 April 2017

The inflamed peripheral nervous system: update on immune therapies

scientific article published on 01 October 2006

The level of B7 homologue 1 expression on brain DC is decisive for CD8 Treg cell recruitment into the CNS during EAE.

scientific article

The metalloproteinase-disintegrin ADAM10 is exclusively expressed by type I muscle fibers

scientific article published on 01 August 2008

The neuroinflammation biobank in the Department of Neurology, University Hospital Muenster, Germany

scientific article published on 12 February 2014

The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice

scientific article

The next-generation sphingosine-1 receptor modulator BAF312 (siponimod) improves cortical network functionality in focal autoimmune encephalomyelitis

scientific article published on 01 November 2019

The non-classical MHC molecule HLA-G protects human muscle cells from immune-mediated lysis: implications for myoblast transplantation and gene therapy

scientific article published on January 2003

The potassium channels TASK2 and TREK1 regulate functional differentiation of murine skeletal muscle cells.

scientific article published on 3 August 2016

The quality of cortical network function recovery depends on localization and degree of axonal demyelination

scientific article

The role of CD8 suppressors versus destructors in autoimmune central nervous system inflammation

scientific article published on 22 August 2008

The role of dendritic cells in CNS autoimmunity

scientific article published on 09 March 2010

The role of leukemia-derived B7-H1 (PD-L1) in tumor-T-cell interactions in humans

scientific article published on July 2006

The role of regulatory T cells in multiple sclerosis

scientific article published on 24 June 2008

The trials and errors in MS therapy

scientific article published on September 2008

The two-pore domain K2 P channel TASK2 drives human NK-cell proliferation and cytolytic function.

scientific article

The two-pore domain potassium channel TASK3 functionally impacts glioma cell death.

scientific article published on 24 January 2008

The ups and downs of multiple sclerosis therapeutics

scientific article published on 01 March 2001

Therapeutic Apheresis in Acute Relapsing Multiple Sclerosis: Current Evidence and Unmet Needs-A Systematic Review

scientific article published on 04 October 2019

Therapeutic approaches in multiple sclerosis: lessons from failed and interrupted treatment trials

scientific article

Therapeutic approaches to multiple sclerosis: an update on failed, interrupted, or inconclusive trials of immunomodulatory treatment strategies

scientific article published on August 2010

Therapeutic approaches to multiple sclerosis: an update on failed, interrupted, or inconclusive trials of neuroprotective and alternative treatment strategies

scientific article published on October 2010

Therapeutic monoclonal antibodies in clinical neurology

scientific article published in June 2010

Therapeutic uses of anti-α4-integrin (anti-VLA-4) antibodies in multiple sclerosis.

scientific article published on 17 October 2014

Therapy with natalizumab is associated with high JCV seroconversion and rising JCV index values.

scientific article published on 27 January 2016

Time-resolved transcriptome and proteome landscape of human regulatory T cell (Treg) differentiation reveals novel regulators of FOXP3.

scientific article published on 7 May 2018

Tolerogenic dendritic cell-based treatment for multiple sclerosis (MS): a harmonised study protocol for two phase I clinical trials comparing intradermal and intranodal cell administration

scientific article published on 09 September 2019

Trafficking of lymphocytes into the CNS.

scientific article published in July 2015

Transcriptional Repressor HIC1 Contributes to Suppressive Function of Human Induced Regulatory T Cells

scientific article published in February 2018

Transforming multiple sclerosis trials into practical reality

scientific article published on 13 May 2011

Treating a GAD65 Antibody-Associated Limbic Encephalitis with Basiliximab: A Case Study.

scientific article published on 3 August 2015

Treating refractory post-herpetic anti-N-methyl-d-aspartate receptor encephalitis with rituximab.

scientific article

Treatment and treatment trials in multiple sclerosis

scientific article published on June 2007

Treatment choices and neuropsychological symptoms of a large cohort of early MS.

scientific article published in March 2018

Treatment of active secondary progressive multiple sclerosis with treosulfan

scientific article published on 20 April 2007

Two pore domain potassium channels in cerebral ischemia: a focus on K2P9.1 (TASK3, KCNK9).

scientific article

Ultraviolet B light attenuates the systemic immune response in central nervous system autoimmunity

scientific article published on 13 May 2014

Upregulation of K2P5.1 potassium channels in multiple sclerosis.

scientific article published on July 2010

VLA-2 blockade in vivo by vatelizumab induces CD4+FoxP3+ regulatory T cells

scientific article published on 01 May 2019

VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells

scientific article published on 18 August 2014

Vascular endothelial growth factor (VEGF) in leptomeningeal metastasis: diagnostic and prognostic value

scientific article published on July 2004

Very bright dorsal columns: spinal magnetic resonance imaging in funicular myelosis

scientific article published on 01 January 2002

Vitiligo after alemtuzumab treatment: Secondary autoimmunity is not all about B cells

scientific article published on 07 November 2018

Volume regulation of murine T lymphocytes relies on voltage-dependent and two-pore domain potassium channels

scientific article published on 5 May 2011

WHO grade associated downregulation of MHC class I antigen-processing machinery components in human astrocytomas: does it reflect a potential immune escape mechanism?

scientific article published on 31 May 2007

Why Most Acute Stroke Studies Are Positive in Animals but Not in Patients: A Systematic Comparison of Preclinical, Early Phase, and Phase 3 Clinical Trials of Neuroprotective Agents

scientific article published on 26 November 2019

Why a positive genetic test for myotonic dystrophy type I does not always imply the right diagnosis

scientific article published on December 2006

[Alemtuzumab for relapsing-remitting multiple sclerosis. Results of two randomized controlled phase III studies]

scientific article published on 01 August 2013

[Blocking adhesion molecules with natalizumab in multiple sclerosis].

scientific article published in August 2005

[Concepts of lesion development in multiple sclerosis. Current approaches and clinical-therapeutic implications ]

scientific article published on 01 February 2006

[Diagnostics and treatment of tuberculosis under immunotherapy for multiple sclerosis : Current status and recommendations in Germany]

scientific article published on 01 December 2019

[Frequency and risk factors associated with post-stroke dementia-an observational study on stroke patients without premorbid cognitive impairment]

scientific article published on 01 February 2020

[Multiple sclerosis -- a channelopathy? Targeting ion channels and transporters in inflammatory neurodegeneration]

scientific article published on 01 April 2009

[Multiple sclerosis. Current review of failed and discontinued clinical trials of drug treatment]

scientific article published on 01 August 2000

[Multiple sclerosis: potential therapeutic options and update of ongoing studies]

scientific article published on 01 June 2004

[Pregabalin and gabapentin in multiple sclerosis: clinical experiences and therapeutic implications]

scientific article published on 01 October 2011

[Prognostic and predictively relevant factors for multiple sclerosis]

scientific article published on 01 October 2014

[Progressive multifocal leukoencephalopathy and rheumatic disease].

scientific article

[Progressive multifocal leukoencephalopathy under natalizumab. Initial possibilities for risk stratification?]

scientific article published on 01 April 2011

[Revision of McDonald's new diagnostic criteria for multiple sclerosis]

scientific article published on 01 October 2006

[Teriflunomide for treatment of multiple sclerosis]

scientific article published on 01 June 2013

[Update on pathophysiologic and immunotherapeutic approaches for the treatment of multiple sclerosis]

scientific article published on 01 August 2007

α4-integrin receptor desaturation and disease activity return after natalizumab cessation

scientific article

Paulina is supported by:

About Paulina

Help