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List of works by Helga Salvesen

A Common Variant at the 14q32 Endometrial Cancer Risk Locus Activates AKT1 through YY1 Binding

scientific article published on June 2016

A national, prospective observational study of first recurrence after primary treatment for gynecological cancer in Norway.

scientific article

A novel wnt regulatory axis in endometrioid endometrial cancer.

scientific article

ARID1A loss is prevalent in endometrial hyperplasia with atypia and low-grade endometrioid carcinomas

scientific article published on 19 October 2012

ATAD2 overexpression links to enrichment of B-MYB-translational signatures and development of aggressive endometrial carcinoma

scientific article

Added Value of Estrogen Receptor, Progesterone Receptor, and L1 Cell Adhesion Molecule Expression to Histology-Based Endometrial Carcinoma Recurrence Prediction Models: An ENITEC Collaboration Study

scientific article published on 10 January 2018

Adult body mass index and risk of ovarian cancer by subtype: a Mendelian randomization study

scientific article published on 10 July 2016

Adult height is associated with increased risk of ovarian cancer: a Mendelian randomisation study

scientific article published on 20 March 2018

Analyses of germline variants associated with ovarian cancer survival identify functional candidates at the 1q22 and 19p12 outcome loci

scientific article published on 15 June 2017

Androgen receptor as potential therapeutic target in metastatic endometrial cancer

scientific article published on 30 June 2016

Annexin-A2 as predictor biomarker of recurrent disease in endometrial cancer

scientific article published on 29 September 2014

Asparaginase-like protein 1 is an independent prognostic marker in primary endometrial cancer, and is frequently lost in metastatic lesions

scientific article published on 30 October 2017

Assessing the genetic architecture of epithelial ovarian cancer histological subtypes

scientific article

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer

scientific article published on 21 June 2016

Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study

scientific article published on 4 September 2016

BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers

scientific article

Biologic markers in endometrial cancer treatment

scientific article published on October 2009

Blocking 17β-hydroxysteroid dehydrogenase type 1 in endometrial cancer: a potential novel endocrine therapeutic approach

scientific article

C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease

scientific article published on 31 July 2017

CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer

scientific article

Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk

scientific article published in February 2015

Changes in Chromatin Structure in Curettage Specimens Identifies High-Risk Patients in Endometrial Cancer

scientific article published in September 2016

Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer

scientific article published on 22 September 2015

Clinicopathologic and molecular markers in cervical carcinoma: a prospective cohort study

scientific article published on 06 June 2017

Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk

scientific article published on 19 June 2015

Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC).

scientific article

Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer

scientific article

Comparison of nucleic acid targets prepared from total RNA or poly(A) RNA for DNA oligonucleotide microarray hybridization

scientific article published on 18 March 2007

Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer

scientific article published in October 2015

Comprehensive genomic profiles of small cell lung cancer

scientific article published on 13 July 2015

Consortium analysis of gene and gene-folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk

scientific article

Correction: The Dynamics and Prognostic Potential of DNA Methylation Changes at Stem Cell Gene Loci in Women's Cancer

article

Correlation of Smoking-Associated DNA Methylation Changes in Buccal Cells With DNA Methylation Changes in Epithelial Cancer

scientific article

Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth

scientific article published on 30 June 2017

Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth

scientific article published on 24 June 2016

Deoxyribonucleic acid ploidy in endometrial carcinoma: a reproducible and valid prognostic marker in a routine diagnostic setting

scientific article published on 03 October 2009

Drug-sensitive FGFR2 mutations in endometrial carcinoma

scholarly article

Dynamic contrast-enhanced MRI in endometrial carcinoma identifies patients at increased risk of recurrence

scientific article published on 4 June 2013

ESGO Statement on the Role of CA‐125 Measurement in Follow-Up of Epithelial Ovarian Cancer

scientific article published in January 2012

EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast

scientific article published on 5 December 2005

Elevated Plasma Growth Differentiation Factor-15 Correlates with Lymph Node Metastases and Poor Survival in Endometrial Cancer ⬇️

scientific article published on May 26, 2011

Endometrial cancer cells exhibit high expression of p110β and its selective inhibition induces variable responses on PI3K signaling, cell survival and proliferation

scientific article published on 16 December 2016

Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci

scientific article published on 19 January 2017

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

scientific article published in 2013

Epithelial-Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk

scientific article

Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study

scientific article published on 17 December 2014

Evolution in Endometrial Cancer: Evidence From an Immunohistochemical Study ⬇️

scientific article published on 01 February 2011

Expression of L1CAM in curettage or high L1CAM level in preoperative blood samples predicts lymph node metastases and poor outcome in endometrial cancer patients

scientific article

Expression of glucocorticoid receptor is associated with aggressive primary endometrial cancer and increases from primary to metastatic lesions

scientific article published on 16 September 2017

Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk

scientific article

Five endometrial cancer risk loci identified through genome-wide association analysis

scientific article published on 02 May 2016

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

scientific article published on 7 September 2016

GALR1 methylation in vaginal swabs is highly accurate in identifying women with endometrial cancer.

scientific article published in July 2013

GATA3 expression in estrogen receptor alpha-negative endometrial carcinomas identifies aggressive tumors with high proliferation and poor patient survival

scientific article published on 3 July 2008

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

scientific article published on April 2013

Gene expression in fixed tissues and outcome in hepatocellular carcinoma.

scientific article

Gene expression patterns related to vascular invasion and aggressive features in endometrial cancer

scientific article

Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer

scientific article published on 22 August 2016

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

scientific article published in September 2016

Genome-wide association study identifies a common variant associated with risk of endometrial cancer

scientific article

Genome-wide association study identifies a possible susceptibility locus for endometrial cancer

scientific article

Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA.

scientific article published on 5 November 2013

Gynecologic Cancer InterGroup (GCIG) Endometrial Cancer Clinical Trials Planning Meeting: taking endometrial cancer trials into the translational era.

scientific article

HER-2/neu expression is associated with high tumor cell proliferation and aggressive phenotype in a population based patient series of endometrial carcinomas

scientific article published on 01 February 2008

HER2 expression patterns in paired primary and metastatic endometrial cancer lesions

scientific article published on 23 November 2017

HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer

scientific article

High mRNA levels of 17β-hydroxysteroid dehydrogenase type 1 correlate with poor prognosis in endometrial cancer.

scientific article published on 03 December 2016

High phospho-Stathmin(Serine38) expression identifies aggressive endometrial cancer and suggests an association with PI3K inhibition.

scientific article published on 28 March 2013

High visceral fat percentage is associated with poor outcome in endometrial cancer

scientific article published on 19 October 2017

High-throughput interrogation of PIK3CA, PTEN, KRAS, FBXW7 and TP53 mutations in primary endometrial carcinoma

scientific article published on 4 December 2012

High-throughput mutation profiling of primary and metastatic endometrial cancers identifies KRAS, FGFR2 and PIK3CA to be frequently mutated

scientific article

Hormone receptor loss in endometrial carcinoma curettage predicts lymph node metastasis and poor outcome in prospective multicentre trial

scientific article

Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene.

scientific article

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.

scientific article published on January 2013

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

scientific article

Identification of highly connected and differentially expressed gene subnetworks in metastasizing endometrial cancer

scientific article published in PLoS ONE

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

scientific article published on 12 January 2015

Importance of tumour cell invasion in blood and lymphatic vasculature among patients with endometrial carcinoma

scientific article published in January 2009

Improved survival related to changes in endometrial cancer treatment, a 30-year population based perspective ⬇️

scientific article published on February 1, 2012

Increased angiogenesis is associated with a 32-gene expression signature and 6p21 amplification in aggressive endometrial cancer

scientific article published in April 2015

Influence of p53 Isoform Expression on Survival in High-Grade Serous Ovarian Cancers

article published in 2019

Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas

scientific article published on 03 February 2009

Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers

scientific article

Integrative Protein-Based Prognostic Model for Early-Stage Endometrioid Endometrial Cancer

scientific article

Integrative kinome profiling identifies mTORC1/2 inhibition as treatment strategy in ovarian clear cell carcinoma.

scientific article published on 23 April 2018

Intra-Gene DNA Methylation Variability Is a Clinically Independent Prognostic Marker in Women's Cancers

scientific article published on 2 December 2015

L1CAM expression in endometrial carcinomas: an ENITEC collaboration study.

scientific article published on 9 August 2016

Lack of estrogen receptor-α is associated with epithelial-mesenchymal transition and PI3K alterations in endometrial carcinoma

scientific article published on 14 January 2013

Landscape of genomic alterations in cervical carcinomas

scientific article

Late-week surgical treatment of endometrial cancer is associated with worse long-term outcome: Results from a prospective, multicenter study

scientific article published on 3 August 2017

Lipocalin 2 expression is associated with aggressive features of endometrial cancer ⬇️

scientific article published on May 6, 2012

Loss of ASRGL1 expression is an independent biomarker for disease-specific survival in endometrioid endometrial carcinoma.

scientific article published on 7 April 2015

Loss of PTEN expression is associated with metastatic disease in patients with endometrial carcinoma

scientific article published on 01 April 2002

Loss of hMSH2 and hMSH6 expression is frequent in sporadic endometrial carcinomas with microsatellite instability: a population-based study

scientific article published on 01 January 2002

Loss of p63 and cytokeratin 5/6 expression is associated with more aggressive tumors in endometrial carcinoma patients

scientific article published on March 2006

Loss of progesterone receptor links to high proliferation and increases from primary to metastatic endometrial cancer lesions.

scientific article published on 30 September 2014

Low frequency ofBRAFandCDKN2Amutations in endometrial cancer

MDM2 promoter SNP344T>A (rs1196333) status does not affect cancer risk

scientific article

MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk

scientific article

MSI-low, a real phenomenon which varies in frequency among cancer types.

scientific article

Magnetic resonance imaging performs better than endocervical curettage for preoperative prediction of cervical stromal invasion in endometrial carcinomas

scientific article published on 15 May 2012

Markers for individualised therapy in endometrial carcinoma

scientific article published on August 2012

Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

scientific article

Metabolic Tumor Volume on 18F-FDG PET/CT Improves Preoperative Identification of High-Risk Endometrial Carcinoma Patients

scientific article

Molecular assessment of depth of myometrial invasion in stage I endometrial cancer: a model based on K-ras mutation analysis

scientific article published on 01 October 2003

Molecular determinants of outcome with mammalian target of rapamycin inhibition in endometrial cancer

scientific article published on 15 February 2014

Molecular pathogenesis and prognostic factors in endometrial carcinoma

scientific article

Molecular profiling in fresh tissue with high tumor cell content promotes enrichment for aggressive adenocarcinomas in cervix

scientific article published on 22 July 2014

Molecular profiling of circulating tumor cells links plasticity to the metastatic process in endometrial cancer

scientific article

Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients

scientific article

Multimodal Imaging of Orthotopic Mouse Model of Endometrial Carcinoma

scientific article published on 7 August 2015

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer

scientific article

Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk

scientific article

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

scientific article published in May 2015

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

scientific article published in December 2016

PI3K pathway in gynecologic malignancies

scientific article published on January 2013

PIK3CA Amplification Associates with Aggressive Phenotype but Not Markers of AKT-MTOR Signaling in Endometrial Carcinoma

scientific article published on 15 November 2018

PIK3CA exon9 mutations associate with reduced survival, and are highly concordant between matching primary tumors and metastases in endometrial cancer

scientific article published on 31 August 2017

PTEN loss is a context-dependent outcome determinant in obese and non-obese endometrioid endometrial cancer patients

scientific article

Pathologic expression of p53 or p16 in preoperative curettage specimens identifies high-risk endometrial carcinomas

scientific article published on 3 May 2006

Plasma calprotectin concentrations in women with endometrial carcinoma

scientific article published on 03 July 2009

Polymorphisms in inflammation pathway genes and endometrial cancer risk

scientific article published on 5 December 2012

Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas-an ENITEC Group Initiative

scientific article

Preoperative anemia, leukocytosis and thrombocytosis identify aggressive endometrial carcinomas

scientific article published in September 2013

Preoperative imaging markers and PDZ-binding kinase tissue expression predict low-risk disease in endometrial hyperplasias and low grade cancers

scientific article published on 31 July 2017

Preoperative tumor size at MRI predicts deep myometrial invasion, lymph node metastases, and patient outcome in endometrial carcinomas

scientific article

Profiles of genomic instability in high-grade serous ovarian cancer predict treatment outcome

scientific article

Prognostic impact of alterations in P-cadherin expression and related cell adhesion markers in endometrial cancer

scientific article published in April 2004

Prognostic importance of glomeruloid microvascular proliferation indicates an aggressive angiogenic phenotype in human cancers

article

Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth

scientific article published on 10 May 2016

Ri antibodies in patients with breast, ovarian or small cell lung cancer determined by a sensitive immunoprecipitation technique

scientific article published on 21 January 2006

Risk of ovarian cancer and the NF-κB pathway: genetic association with IL1A and TNFSF10

scientific article published on 22 November 2013

Role of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development

scientific journal article

SNP285C modulates oestrogen receptor/Sp1 binding to the MDM2 promoter and reduces the risk of endometrial but not prostatic cancer

scientific article published on 24 November 2011

Shared genetics underlying epidemiological association between endometriosis and ovarian cancer

scientific article published on 30 July 2015

Significance of CD 105 expression for tumour angiogenesis and prognosis in endometrial carcinomas

scientific article published in November 2003

Significance of PTEN alterations in endometrial carcinoma: a population-based study of mutations, promoter methylation and PTEN protein expression

scientific article published on 01 December 2004

Somatic mutation profiles of clear cell endometrial tumors revealed by whole exome and targeted gene sequencing

scientific article

Staffing and emergency service in Norwegian obstetrics and gynecology departments

scientific article published in November 2004

Standard 1.5-T MRI of endometrial carcinomas: modest agreement between radiologists.

scientific article published on 28 March 2012

Stathmin is superior to AKT and phospho‐AKT staining for the detection of phosphoinositide 3‐kinase activation and aggressive endometrial cancer ⬇️

scientific article published on October 1, 2010

Stathmin overexpression identifies high-risk patients and lymph node metastasis in endometrial cancer

scientific article published on 17 January 2011

Stathmin protein level, a potential predictive marker for taxane treatment response in endometrial cancer

scientific article

Stratification based on high tumour cell content in fresh frozen tissue promotes selection of aggressive endometrial carcinomas

scientific article published on 14 December 2011

Subspecialist training in surgical gynecologic oncology in the Nordic countries ⬇️

scientific article published on June 16, 2011

Switch in FOXA1 status associates with endometrial cancer progression

scientific article

The MDM2 Promoter SNP285C/309G Haplotype Diminishes Sp1 Transcription Factor Binding and Reduces Risk for Breast and Ovarian Cancer in Caucasians

article

The MDM4 SNP34091 (rs4245739) C-allele is associated with increased risk of ovarian-but not endometrial cancer

scientific article published on 11 February 2016

The Role of Adjuvant Chemotherapy in Surgical Stages I-II Serous and Clear Cell Carcinomas and Carcinosarcoma of the Endometrium: A Collaborative Study ⬇️

scientific article published on 01 February 2011

The dynamics and prognostic potential of DNA methylation changes at stem cell gene loci in women's cancer

scientific article

The genetic landscape of 87 ovarian germ cell tumors

scientific article published on 28 August 2018

The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis

scientific article published on 27 June 2016

Tissue and imaging biomarkers for hypoxia predict poor outcome in endometrial cancer

scientific article published on 13 September 2016

Training in Bowel and Upper Abdominal Surgery in Gynaecological Oncology

scientific article published in June 2011

Tumor necrosis is an important hallmark of aggressive endometrial cancer and associates with hypoxia, angiogenesis and inflammation responses

scientific article published on 14 October 2015

Type of vascular invasion in association with progress of endometrial cancer.

scientific article published on 4 October 2017

Vascular proliferation is important for clinical progress of endometrial cancer

scientific article published on 01 March 2006

What Is the Best Preoperative Imaging for Endometrial Cancer?

scientific article

White Blood Cell BRCA1 Promoter Methylation Status and Ovarian Cancer Risk

scientific article published on 16 January 2018

[Molecular diagnostic techniques in gynaecologic cancer]

scientific article published on 01 November 2005

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