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List of works by Frances A. Shepherd

A phase I study of foretinib plus erlotinib in patients with previously treated advanced non-small cell lung cancer: Canadian cancer trials group IND.196.

scientific article published on 28 June 2017

A phase I/II study of GTI-2040 plus docetaxel as second-line treatment in advanced non-small cell lung cancer: a study of the PMH phase II consortium

scientific article published on September 2009

A phase II trial of saracatinib, an inhibitor of src kinases, in previously-treated advanced non-small-cell lung cancer: the princess margaret hospital phase II consortium

scientific article published on 26 October 2013

A pooled exploratory analysis of the effect of tumor size and KRAS mutations on survival benefit from adjuvant platinum-based chemotherapy in node-negative non-small cell lung cancer

scientific article

A systematic review and Canadian consensus recommendations on the use of biomarkers in the treatment of non-small cell lung cancer.

scientific article

Adjuvant chemotherapy for resected early-stage non-small cell lung cancer

scientific article

Adoption of adjuvant chemotherapy for non-small-cell lung cancer: a population-based outcomes study

scientific article

Age and comorbidity as independent prognostic factors in the treatment of non small-cell lung cancer: a review of National Cancer Institute of Canada Clinical Trials Group trials

scientific article published on January 2008

Angiotensin-Converting Enzyme and Aldosterone Serum Levels as Prognostic and Predictive Biomarkers for Cediranib in NCIC Clinical Trials Group Study BR.24.

scientific article published on 13 May 2015

Anticoagulation and bleeding: a pooled analysis of lung cancer trials of the NCIC Clinical Trials Group

scientific article

BRM Promoter Polymorphisms and Survival of Advanced Non-Small Cell Lung Cancer Patients in the Princess Margaret Cohort and CCTG BR.24 Trial

scientific article published on 8 November 2016

Characterizing the cancer genome in lung adenocarcinoma

scientific article

Chemotherapy for relapsed small cell lung cancer: a systematic review and practice guideline

scientific article

ERCC1 isoform expression and DNA repair in non-small-cell lung cancer

scientific article

Exploiting the noise: improving biomarkers with ensembles of data analysis methodologies

scientific article

Gefitinib versus placebo in completely resected non-small-cell lung cancer: results of the NCIC CTG BR19 study

scientific article

K-ras mutations in non-small-cell lung carcinoma: a review

scientific article

KIF14 messenger RNA expression is independently prognostic for outcome in lung cancer

scientific article

LACE-Bio: Validation of Predictive and/or Prognostic Immunohistochemistry/Histochemistry-based Biomarkers in Resected Non-small-cell Lung Cancer

article

Lung cancer in 2013: state of the art therapy for metastatic disease

scientific article

Lung cancer risk in never-smokers: a population-based case-control study of epidemiologic risk factors

scientific article

Lung cancer susceptibility locus at 5p15.33

scientific article

Meta-analysis of individual patient data from randomized trials of chemotherapy plus cetuximab as first-line treatment for advanced non-small cell lung cancer

scientific article

Molecular predictors of outcome with gefitinib and docetaxel in previously treated non-small-cell lung cancer: data from the randomized phase III INTEREST trial

scientific article

Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial.

scientific article published on 25 October 2016

NCIC CTG IND.190 phase I trial of dalotuzumab (MK-0646) in combination with cisplatin and etoposide in extensive-stage small-cell lung cancer

scientific article published in March 2014

Novel candidate tumor marker genes for lung adenocarcinoma

scientific article (publication date: 24 October 2002)

Optimized application of penalized regression methods to diverse genomic data

scientific article

Osimertinib for pretreated EGFR Thr790Met-positive advanced non-small-cell lung cancer (AURA2): a multicentre, open-label, single-arm, phase 2 study

scientific article

Phase I and pharmacokinetic study of daily oral AZD2171, an inhibitor of vascular endothelial growth factor tyrosine kinases, in combination with carboplatin and paclitaxel in patients with advanced non-small-cell lung cancer: the National Cancer In

scientific article published on April 2008

Phase III study comparing oral topotecan to intravenous docetaxel in patients with pretreated advanced non-small-cell lung cancer

scientific article

Plasma transforming growth factor alpha and amphiregulin protein levels in NCIC Clinical Trials Group BR.21.

scientific article published on 15 November 2010

Pooled Analysis of the Prognostic and Predictive Effects of TP53 Comutation Status Combined With KRAS or EGFR Mutation in Early-Stage Resected Non-Small-Cell Lung Cancer in Four Trials of Adjuvant Chemotherapy

scientific article published on 28 April 2017

Pooled Analysis of the Prognostic and Predictive Value of KRAS Mutation Status and Mutation Subtype in Patients with Non-Small Cell Lung Cancer Treated with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

scientific article published on 31 December 2015

Pooled analysis of the prognostic and predictive effects of KRAS mutation status and KRAS mutation subtype in early-stage resected non-small-cell lung cancer in four trials of adjuvant chemotherapy

scientific article

Prognostic Effect of Tumor Lymphocytic Infiltration in Resectable Non-Small-Cell Lung Cancer

scientific article published on February 2016

Prognostic and Predictive Effect of TP53 Mutations in Patients with Non-Small Cell Lung Cancer from Adjuvant Cisplatin-Based Therapy Randomized Trials: A LACE-Bio Pooled Analysis

scientific article

Prognostic and predictive gene signature for adjuvant chemotherapy in resected non-small-cell lung cancer

scientific article

Prognostic and predictive value of epidermal growth factor receptor tyrosine kinase domain mutation status and gene copy number for adjuvant chemotherapy in non-small cell lung cancer

scientific article

Prognostic gene signatures for non-small-cell lung cancer

scientific article

Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer

scientific article

Randomized phase II trial of concurrent versus sequential bortezomib plus docetaxel in advanced non-small-cell lung cancer: a California cancer consortium trial.

scientific article published in January 2011

Randomized phase III trial of amrubicin versus topotecan as second-line treatment for patients with small-cell lung cancer

scientific article

Randomized phase III trial of vinorelbine plus cisplatin compared with observation in completely resected stage IB and II non-small-cell lung cancer: updated survival analysis of JBR-10.

scientific article

Randomized, double-blind trial of carboplatin and paclitaxel with either daily oral cediranib or placebo in advanced non-small-cell lung cancer: NCIC clinical trials group BR24 study

scientific article

Relationship between EGFR expression, EGFR mutation status, and the efficacy of chemotherapy plus cetuximab in FLEX study patients with advanced non-small-cell lung cancer

scientific article

Resident preparedness in discussing prognosis in patients with advanced lung cancer.

scientific article

Resource utilization and costs during the initial years of lung cancer screening with computed tomography in Canada

scientific article

Small cell lung cancer and targeted therapies.

scientific article

Surrogate endpoints for overall survival in chemotherapy and radiotherapy trials in operable and locally advanced lung cancer: a re-analysis of meta-analyses of individual patients' data

scientific article

TRIM14 is a Putative Tumor Suppressor and Regulator of Innate Immune Response in Non-Small Cell Lung Cancer

scientific article

The Cost-Effectiveness of High-Risk Lung Cancer Screening and Drivers of Program Efficiency.

scientific article published on 09 May 2017

The IASLC Lung Cancer Staging Project: data elements for the prospective project

scientific article

Tumor cavitation: impact on objective response evaluation in trials of angiogenesis inhibitors in non-small-cell lung cancer.

scientific article published on December 2008

Twenty-five years of clinical research for patients with limited-stage small cell lung carcinoma in North America

scientific article

Use of the epidermal growth factor receptor inhibitors gefitinib and erlotinib in the treatment of non-small cell lung cancer: a systematic review.

scientific article

Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer

scientific article

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