List of works - Jacob Madsen

(64)Cu-NODAGA-c(RGDyK) Is a Promising New Angiogenesis PET Tracer: Correlation between Tumor Uptake and Integrin α(V)β(3) Expression in Human Neuroendocrine Tumor Xenografts

scientific article

11C-NS14492 as a novel PET radioligand for imaging cerebral alpha7 nicotinic acetylcholine receptors: in vivo evaluation and drug occupancy measurements

scientific article published on 9 August 2011

68Ga-labeling and in vivo evaluation of a uPAR binding DOTA- and NODAGA-conjugated peptide for PET imaging of invasive cancers

scientific article

A nonlinear relationship between cerebral serotonin transporter and 5-HT(2A) receptor binding: an in vivo molecular imaging study in humans ⬇️

scientific article (publication date: 3 March 2010)

A probabilistic approach to delineating functional brain regions

scientific article

Abstract 4771: PET imaging of tissue factor using 64Cu-labeled active site-inhibited factor VII: A potential companion diagnostic for tissue factor targeted cancer therapies

Abstract 4930: Quantitative PET imaging of tissue factor expression using 18F-labeled active site inhibited factor VIIa

Abstract 5174: Imaging of tissue factor expression in an orthotopic pancreatic tumor mouse model using small animal PET/CT and MRI

Abstract 5220: Early prediction of tumor response to APO866 treatment with 3′-deoxy-3′-[18F]fluorothymidine positron emission tomography in human ovary cancer xenografts in mice

Abstract 5237: Non-invasive detection of urokinase-type plasminogen activator receptor (uPAR) expression in four human cancer xenograft mouse models using microPET/CT

Abstract 5280: PET imaging of proteolysis: Evaluation of 68Ga-DOTA and 68Ga-NODAGA chelates of an uPAR-specific peptide in a human glioblastoma xenograft model

Abstract 5308: PET imaging of hypoxia with [64]Cu-ATSM in human ovarian cancer: Comparison of xenografts in mice and rats

Abstract 5315: PET imaging with the proliferation tracer 18F-FLT as early, non-invasive predictor of everolimus effect on tumor growth: Studies in human neuroendocrine tumor xenografts in mice

Abstract 5320: Changes in [18]F-FLT and [18]F-FDG positron emission tomography following treatment with belinostat alone and in combination with paclitaxel/carboplatin in human ovary cancer xenografts in mice

Accelerating preclinical PET-screening: reductive amination with [11C]methoxybenzaldehydes

scholarly article in RSC Advances, vol. 4 no. 41, 2014

Affinity-Guided Conjugation to Antibodies for Use in Positron Emission Tomography

scientific article published on 12 March 2019

Angiogenesis PET Tracer Uptake ((68)Ga-NODAGA-E[(cRGDyK)]₂) in Induced Myocardial Infarction in Minipigs

scientific article published on 17 June 2016

Angiogenesis PET Tracer Uptake (68Ga-NODAGA-E[(cRGDyK)]₂) in Induced Myocardial Infarction and Stromal Cell Treatment in Minipigs.

scientific article published on 16 May 2018

Brain serotonin 2A receptor binding: relations to body mass index, tobacco and alcohol use.

scientific article

Central 5-HT neurotransmission modulates weight loss following gastric bypass surgery in obese individuals.

scientific article published in April 2015

Central 5-HT4 receptor binding as biomarker of serotonergic tonus in humans: a [11C]SB207145 PET study

scientific article published on 5 November 2013

Cerebral 5-HT2A receptor and serotonin transporter binding in humans are not affected by the val66met BDNF polymorphism status or blood BDNF levels

scientific article

Cognitive function is related to fronto-striatal serotonin transporter levels--a brain PET study in young healthy subjects

scientific article published on 10 July 2010

Comparison of two new angiogenesis PET tracers 68Ga-NODAGA-E[c(RGDyK)]2 and (64)Cu-NODAGA-E[c(RGDyK)]2; in vivo imaging studies in human xenograft tumors

scientific article published on 12 December 2013

Corrigendum to “Brain serotonin 2A receptor binding: Relations to body mass index, tobacco and alcohol use” [NeuroImage 46 (2009) 23–30]

scholarly article by David Erritzøe et al published August 2009 in NeuroImage

Cortical and Subcortical 5-HT2A Receptor Binding in Neuroleptic-Naive First-Episode Schizophrenic Patients

scientific article (publication date: 20 February 2008)

Decreased Frontal Serotonin2A Receptor Binding in Antipsychotic-Naive Patients With First-Episode Schizophrenia

scientific article (publication date: 2010)

Development of a (11)C-labeled tetrazine for rapid tetrazine-trans-cyclooctene ligation

scientific article published on 27 March 2013

Dosimetry of 64Cu-DOTA-AE105, a PET tracer for uPAR imaging

scientific article published on 18 December 2013

Early detection of response to experimental chemotherapeutic Top216 with [18F]FLT and [18F]FDG PET in human ovary cancer xenografts in mice

scientific article

Effect of antidepressant treatment on 5-HT4 receptor binding and associations with clinical outcomes and verbal memory in major depressive disorder

scientific article published in August 2024

Endogenous plasma estradiol in healthy men is positively correlated with cerebral cortical serotonin 2A receptor binding

scientific article

Evaluation of the Serotonin Transporter Ligand 123I-ADAM for SPECT Studies on Humans

scientific article

Familial risk for mood disorder and the personality risk factor, neuroticism, interact in their association with frontolimbic serotonin 2A receptor binding

scientific article

First (18)F-labeled ligand for PET imaging of uPAR: in vivo studies in human prostate cancer xenografts

scientific article

First-in-human uPAR PET: Imaging of Cancer Aggressiveness

scientific article

Fluorine-18 labelled aldehydes as prosthetic groups for oxime coupling with a FVIIa protein

scientific article published on 11 December 2020

Gas phase production of[11C]methyl iodide-d3. Synthesis and biological evaluation ofS-[N-methyl-11C]citalopram and deuterated analogues

article

Gender and the use of hormonal contraception in women are not associated with cerebral cortical 5-HT 2A receptor binding.

scientific article published on 25 June 2009

Genetic variants and brain binding potentials: Lost in translation?

scientific article published in August 2010

HPLC methods for the purification of [11C]-labelled radiopharmaceuticals: reversal of the retention order of products and precursors

High familial risk for mood disorder is associated with low dorsolateral prefrontal cortex serotonin transporter binding

scientific article

High tumor uptake of 64Cu: Implications for molecular imaging of tumor characteristics with copper-based PET tracers ⬇️

scientific article published on February 6, 2013

Imaging of treatment response to the combination of carboplatin and paclitaxel in human ovarian cancer xenograft tumors in mice using FDG and FLT PET

scientific article

Improved PET imaging of uPAR expression using new (64)Cu-labeled cross-bridged peptide ligands: comparative in vitro and in vivo studies

scientific article

In abstinent MDMA users the cortisol awakening response is off-set but associated with prefrontal serotonin transporter binding as in non-users

scientific article published on 14 February 2014

In vivo evaluation of a series of substituted 11C-phenetylamines as 5-HT2A agonist PET tracers

In vivo imaging of cerebral serotonin transporter and serotonin(2A) receptor binding in 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") and hallucinogen users

scientific article published in June 2011

Increased cellular proliferation in rat skeletal muscle and tendon in response to exercise: use of FLT and PET/CT.

scientific article published in December 2010

Low frontal serotonin 2A receptor binding is a state marker for schizophrenia?

scientific article

Neuroimaging of the serotonin reuptake site requires high-affinity ligands

scientific article published in November 2007

New peptide receptor radionuclide therapy of invasive cancer cells: in vivo studies using 177Lu-DOTA-AE105 targeting uPAR in human colorectal cancer xenografts

scientific article published on 26 June 2012

No change in [¹¹C]CUMI-101 binding to 5-HT(1A) receptors after intravenous citalopram in human

scientific article published on 20 July 2012

Noninvasive 64Cu-ATSM and PET/CT assessment of hypoxia in rat skeletal muscles and tendons during muscle contractions

scientific article

On the consensus nomenclature rules for radiopharmaceutical chemistry - Reconsideration of radiochemical conversion

scientific article published on 18 November 2020

One-Step Synthesis of N-Succinimidyl-4-[18F]Fluorobenzoate ([18F]SFB)

scientific article published on 22 September 2019

Oxime Coupling of Active Site Inhibited Factor Seven with a Nonvolatile, Water-Soluble Fluorine-18 Labeled Aldehyde

scientific article published on 06 February 2019

P.489 Resting-state default mode network functional connectivity associations with personality trait openness to experience

scientific article published in 2019

PET Imaging of Tissue Factor in Pancreatic Cancer Using 64Cu-Labeled Active Site-Inhibited Factor VII.

scientific article published on 24 March 2016

Pharmacokinetic Analysis of (64)Cu-ATSM Dynamic PET in Human Xenograft Tumors in Mice

scientific article

Preclinical safety assessment of the 5-HT2A receptor agonist PET radioligand [ 11C]Cimbi-36.

scientific article

Prefrontal serotonin transporter availability is positively associated with the cortisol awakening response

scientific article

Quantification of 5-HT2A receptors in the human brain using [18F]altanserin-PET and the bolus/infusion approach

scientific article

Quantitative PET Imaging of Tissue Factor Expression Using 18F-Labeled Active Site-Inhibited Factor VII.

scientific article published on 17 September 2015

Quantitative PET of human urokinase-type plasminogen activator receptor with 64Cu-DOTA-AE105: implications for visualizing cancer invasion

scientific article published on January 2012

Radiolabelling and PET brain imaging of the α₁-adrenoceptor antagonist Lu AE43936.

scientific article published on 17 November 2012

Radiosynthesis and evaluation of 11C-CIMBI-5 as a 5-HT2A receptor agonist radioligand for PET.

scientific article

Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT (2A) agonist PET tracers

scientific article

Recombinant coagulation factor VIIa labelled with the fac-99 mTc(CO)3-core: synthesis and in vitro evaluation of a putative new radiopharmaceutical for imaging in acute bleeding lesion

article

Reduced 5-HT2A receptor binding in patients with mild cognitive impairment

scientific article

Reproducibility of 5-HT2A receptor measurements and sample size estimations with [18F]altanserin PET using a bolus/infusion approach

scientific article

Safety, Dosimetry, and Tumor Detection Ability of 68Ga-NOTA-AE105: First-in-Human Study of a Novel Radioligand for uPAR PET Imaging

scientific article

Seasonal difference in brain serotonin transporter binding predicts symptom severity in patients with seasonal affective disorder

scientific article

Seasonality-resilient individuals downregulate their cerebral 5-HT transporter binding in winter – A longitudinal combined 11 C-DASB and 11 C-SB207145 PET study

article

Serotonin 2A receptor agonist binding in the human brain with [¹¹C]Cimbi-36.

scientific article

Site-Specific 64Cu Labeling of the Serine Protease, Active Site Inhibited Factor Seven Azide (FVIIai-N3), Using Copper Free Click Chemistry

scientific article published on 5 December 2017

Synthesis and biological evaluation of 125I/123I-labelled analogues of citalopram and escitalopram as potential radioligands for imaging of the serotonin transporter

scholarly article by Jacob Madsen et al published 30 November 2010 in Journal of Labelled Compounds and Radiopharmaceuticals

Synthesis and biological evaluation of novel carbon-11-labelled analogues of citalopram as potential radioligands for the serotonin transporter

scientific article published in August 2003

Synthesis and characterization of (18)F-labeled active site inhibited factor VII (ASIS).

scientific article published on 27 March 2015

The personality trait openness is related to cerebral 5-HTT levels

scientific article (publication date: April 2009)

The use of longitudinal 18F-FET MicroPET imaging to evaluate response to irinotecan in orthotopic human glioblastoma multiforme xenografts

scientific article

Urokinase Plasminogen Activator Receptor (uPAR) PET/MRI of Prostate Cancer for Non-invasive Evaluation of Aggressiveness: a Prospective Phase II Clinical Trial Comparing with Gleason Score

scientific article published on 06 August 2020

Urokinase-Type Plasminogen Activator Receptor as a Potential PET Biomarker in Glioblastoma

scientific article published in October 2015

Use of Cis-[18F]Fluoro-Proline for Assessment of Exercise-Related Collagen Synthesis in Musculoskeletal Connective Tissue ⬇️

scientific article published on February 11, 2011

[18F]FDG and [18F]FLT positron emission tomography imaging following treatment with belinostat in human ovary cancer xenografts in mice

scientific article

[18F]FLT PET for non-invasive assessment of tumor sensitivity to chemotherapy: studies with experimental chemotherapy TP202377 in human cancer xenografts in mice

scientific article

[18F]FLT and [18F]FDG PET for non-invasive treatment monitoring of the nicotinamide phosphoribosyltransferase inhibitor APO866 in human xenografts

scientific article

uPAR targeted radionuclide therapy with (177)Lu-DOTA-AE105 inhibits dissemination of metastatic prostate cancer

scientific article

List of works by Jacob Madsen

(64)Cu-NODAGA-c(RGDyK) Is a Promising New Angiogenesis PET Tracer: Correlation between Tumor Uptake and Integrin α(V)β(3) Expression in Human Neuroendocrine Tumor Xenografts

11C-NS14492 as a novel PET radioligand for imaging cerebral alpha7 nicotinic acetylcholine receptors: in vivo evaluation and drug occupancy measurements

68Ga-labeling and in vivo evaluation of a uPAR binding DOTA- and NODAGA-conjugated peptide for PET imaging of invasive cancers

A nonlinear relationship between cerebral serotonin transporter and 5-HT(2A) receptor binding: an in vivo molecular imaging study in humans ⬇️

A probabilistic approach to delineating functional brain regions

Abstract 4771: PET imaging of tissue factor using 64Cu-labeled active site-inhibited factor VII: A potential companion diagnostic for tissue factor targeted cancer therapies

Abstract 4930: Quantitative PET imaging of tissue factor expression using 18F-labeled active site inhibited factor VIIa

Abstract 5174: Imaging of tissue factor expression in an orthotopic pancreatic tumor mouse model using small animal PET/CT and MRI

Abstract 5220: Early prediction of tumor response to APO866 treatment with 3′-deoxy-3′-[18F]fluorothymidine positron emission tomography in human ovary cancer xenografts in mice

Abstract 5237: Non-invasive detection of urokinase-type plasminogen activator receptor (uPAR) expression in four human cancer xenograft mouse models using microPET/CT

Abstract 5280: PET imaging of proteolysis: Evaluation of 68Ga-DOTA and 68Ga-NODAGA chelates of an uPAR-specific peptide in a human glioblastoma xenograft model

Abstract 5308: PET imaging of hypoxia with [64]Cu-ATSM in human ovarian cancer: Comparison of xenografts in mice and rats

Abstract 5315: PET imaging with the proliferation tracer 18F-FLT as early, non-invasive predictor of everolimus effect on tumor growth: Studies in human neuroendocrine tumor xenografts in mice

Abstract 5320: Changes in [18]F-FLT and [18]F-FDG positron emission tomography following treatment with belinostat alone and in combination with paclitaxel/carboplatin in human ovary cancer xenografts in mice

Accelerating preclinical PET-screening: reductive amination with [11C]methoxybenzaldehydes

Affinity-Guided Conjugation to Antibodies for Use in Positron Emission Tomography

Angiogenesis PET Tracer Uptake ((68)Ga-NODAGA-E[(cRGDyK)]₂) in Induced Myocardial Infarction in Minipigs

Angiogenesis PET Tracer Uptake (68Ga-NODAGA-E[(cRGDyK)]₂) in Induced Myocardial Infarction and Stromal Cell Treatment in Minipigs.

Brain serotonin 2A receptor binding: relations to body mass index, tobacco and alcohol use.

Central 5-HT neurotransmission modulates weight loss following gastric bypass surgery in obese individuals.

Central 5-HT4 receptor binding as biomarker of serotonergic tonus in humans: a [11C]SB207145 PET study

Cerebral 5-HT2A receptor and serotonin transporter binding in humans are not affected by the val66met BDNF polymorphism status or blood BDNF levels

Cognitive function is related to fronto-striatal serotonin transporter levels--a brain PET study in young healthy subjects

Comparison of two new angiogenesis PET tracers 68Ga-NODAGA-E[c(RGDyK)]2 and (64)Cu-NODAGA-E[c(RGDyK)]2; in vivo imaging studies in human xenograft tumors

Corrigendum to “Brain serotonin 2A receptor binding: Relations to body mass index, tobacco and alcohol use” [NeuroImage 46 (2009) 23–30]

Cortical and Subcortical 5-HT2A Receptor Binding in Neuroleptic-Naive First-Episode Schizophrenic Patients

Decreased Frontal Serotonin2A Receptor Binding in Antipsychotic-Naive Patients With First-Episode Schizophrenia

Development of a (11)C-labeled tetrazine for rapid tetrazine-trans-cyclooctene ligation

Dosimetry of 64Cu-DOTA-AE105, a PET tracer for uPAR imaging

Early detection of response to experimental chemotherapeutic Top216 with [18F]FLT and [18F]FDG PET in human ovary cancer xenografts in mice

Effect of antidepressant treatment on 5-HT4 receptor binding and associations with clinical outcomes and verbal memory in major depressive disorder

Endogenous plasma estradiol in healthy men is positively correlated with cerebral cortical serotonin 2A receptor binding

Evaluation of the Serotonin Transporter Ligand 123I-ADAM for SPECT Studies on Humans

Familial risk for mood disorder and the personality risk factor, neuroticism, interact in their association with frontolimbic serotonin 2A receptor binding

First (18)F-labeled ligand for PET imaging of uPAR: in vivo studies in human prostate cancer xenografts

First-in-human uPAR PET: Imaging of Cancer Aggressiveness

Fluorine-18 labelled aldehydes as prosthetic groups for oxime coupling with a FVIIa protein

Gas phase production of[11C]methyl iodide-d3. Synthesis and biological evaluation ofS-[N-methyl-11C]citalopram and deuterated analogues

Gender and the use of hormonal contraception in women are not associated with cerebral cortical 5-HT 2A receptor binding.

Genetic variants and brain binding potentials: Lost in translation?

HPLC methods for the purification of [11C]-labelled radiopharmaceuticals: reversal of the retention order of products and precursors

High familial risk for mood disorder is associated with low dorsolateral prefrontal cortex serotonin transporter binding

High tumor uptake of 64Cu: Implications for molecular imaging of tumor characteristics with copper-based PET tracers ⬇️

Imaging of treatment response to the combination of carboplatin and paclitaxel in human ovarian cancer xenograft tumors in mice using FDG and FLT PET

Improved PET imaging of uPAR expression using new (64)Cu-labeled cross-bridged peptide ligands: comparative in vitro and in vivo studies

In abstinent MDMA users the cortisol awakening response is off-set but associated with prefrontal serotonin transporter binding as in non-users

In vivo evaluation of a series of substituted 11C-phenetylamines as 5-HT2A agonist PET tracers

In vivo imaging of cerebral serotonin transporter and serotonin(2A) receptor binding in 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") and hallucinogen users

Increased cellular proliferation in rat skeletal muscle and tendon in response to exercise: use of FLT and PET/CT.

Low frontal serotonin 2A receptor binding is a state marker for schizophrenia?

Neuroimaging of the serotonin reuptake site requires high-affinity ligands

New peptide receptor radionuclide therapy of invasive cancer cells: in vivo studies using 177Lu-DOTA-AE105 targeting uPAR in human colorectal cancer xenografts

No change in [¹¹C]CUMI-101 binding to 5-HT(1A) receptors after intravenous citalopram in human

Noninvasive 64Cu-ATSM and PET/CT assessment of hypoxia in rat skeletal muscles and tendons during muscle contractions

On the consensus nomenclature rules for radiopharmaceutical chemistry - Reconsideration of radiochemical conversion

One-Step Synthesis of N-Succinimidyl-4-[18F]Fluorobenzoate ([18F]SFB)

Oxime Coupling of Active Site Inhibited Factor Seven with a Nonvolatile, Water-Soluble Fluorine-18 Labeled Aldehyde

P.489 Resting-state default mode network functional connectivity associations with personality trait openness to experience

PET Imaging of Tissue Factor in Pancreatic Cancer Using 64Cu-Labeled Active Site-Inhibited Factor VII.

Pharmacokinetic Analysis of (64)Cu-ATSM Dynamic PET in Human Xenograft Tumors in Mice

Preclinical safety assessment of the 5-HT2A receptor agonist PET radioligand [ 11C]Cimbi-36.

Prefrontal serotonin transporter availability is positively associated with the cortisol awakening response

Quantification of 5-HT2A receptors in the human brain using [18F]altanserin-PET and the bolus/infusion approach

Quantitative PET Imaging of Tissue Factor Expression Using 18F-Labeled Active Site-Inhibited Factor VII.

Quantitative PET of human urokinase-type plasminogen activator receptor with 64Cu-DOTA-AE105: implications for visualizing cancer invasion

Radiolabelling and PET brain imaging of the α₁-adrenoceptor antagonist Lu AE43936.

Radiosynthesis and evaluation of 11C-CIMBI-5 as a 5-HT2A receptor agonist radioligand for PET.

Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT (2A) agonist PET tracers

Recombinant coagulation factor VIIa labelled with the fac-99 mTc(CO)3-core: synthesis and in vitro evaluation of a putative new radiopharmaceutical for imaging in acute bleeding lesion

Reduced 5-HT2A receptor binding in patients with mild cognitive impairment

Reproducibility of 5-HT2A receptor measurements and sample size estimations with [18F]altanserin PET using a bolus/infusion approach

Safety, Dosimetry, and Tumor Detection Ability of 68Ga-NOTA-AE105: First-in-Human Study of a Novel Radioligand for uPAR PET Imaging

Seasonal difference in brain serotonin transporter binding predicts symptom severity in patients with seasonal affective disorder

Seasonality-resilient individuals downregulate their cerebral 5-HT transporter binding in winter – A longitudinal combined 11 C-DASB and 11 C-SB207145 PET study

Serotonin 2A receptor agonist binding in the human brain with [¹¹C]Cimbi-36.

Site-Specific 64Cu Labeling of the Serine Protease, Active Site Inhibited Factor Seven Azide (FVIIai-N3), Using Copper Free Click Chemistry

Synthesis and biological evaluation of 125I/123I-labelled analogues of citalopram and escitalopram as potential radioligands for imaging of the serotonin transporter

Synthesis and biological evaluation of novel carbon-11-labelled analogues of citalopram as potential radioligands for the serotonin transporter

Synthesis and characterization of (18)F-labeled active site inhibited factor VII (ASIS).