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List of works by Kamil Kuča

1-(Benzo[d]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders.

scientific article published in December 2018

7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment.

scientific article published on 10 December 2015

<i>Pleurotus</i> Macrofungi-Assisted Nanoparticle Synthesis and Its Potential Applications: A Review

scientific article published on 09 December 2020

A Direct interaction between mitochondrial proteins and amyloid-β peptide and its significance for the progression and treatment of Alzheimer`s disease.

scientific article

A New Method for Extraction and Analysis of Ricin Samples through MALDI-TOF-MS/MS

scientific article published on 03 April 2019

A Novel Herbal Hydrogel Formulation of <i>Moringa oleifera</i> for Wound Healing

scientific article published on 24 December 2020

Acetylcholinesterase and butyrylcholinesterase--important enzymes of human body.

scientific article

Acute Toxic Injuries of Rat's Visceral Tissues Induced by Different Oximes

scientific article published on 11 November 2019

Adjunct use of honey in diabetes mellitus: A consensus or conundrum?

scientific article published in 2020

Aflatoxin Detoxification Using Microorganisms and Enzymes

scientific article published in 2021

Agroinfiltration Mediated Scalable Transient Gene Expression in Genome Edited Crop Plants

scientific article published in 2021

Alterations in Growth and Morphology of Ganoderma lucidum and Volvariella volvaceae in Response to Nanoparticle Supplementation

scientific article published on 27 August 2020

Alzheimer's disease and its treatment costs: case study in the Czech Republic

scientific article

Alzheimer's disease and language impairments: social intervention and medical treatment

scientific article

Anorexic responses to trichothecene deoxynivalenol and its congeners correspond to secretion of tumor necrosis factor-α and interleukin-1β

scientific article published on 05 March 2020

Anti-NMDA receptor antibodies in patients with a first episode of schizophrenia

scientific article

Antidotal Potency of the Novel, Structurally Different Adsorbents in Rats Acutely Intoxicated with the T-2 Toxin

scientific article published on 05 October 2020

Antioxidant Functionalized Nanoparticles: A Combat against Oxidative Stress

scientific article published on 08 July 2020

Applications of Nanotechnology in Sensor-Based Detection of Foodborne Pathogens

scientific article published on 01 April 2020

Asoxime (HI-6) impact on dogs after one and tenfold therapeutic doses: assessment of adverse effects, distribution, and oxidative stress.

scientific article

Assistive technologies for managing language disorders in dementia

scientific article

Benzothiazoles - scaffold of interest for CNS targeted drugs.

scientific article

Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17β-HSD10 with Implications to Alzheimer's Disease Treatment

scientific article published on 17 March 2020

Bioactive Compounds of Edible Fruits with Their Anti-Aging Properties: A Comprehensive Review to Prolong Human Life ⬇️

scientific article published on 13 November 2020

Biodegradation of Organophosphorus Compounds Predicted by Enzymatic Process Using Molecular Modelling and Observed in Soil Samples Through Analytical Techniques and Microbiological Analysis: A Comparison

scientific article published on 23 December 2019

Biological degradation of aflatoxins.

scientific article published on January 2009

Breast Cancer Detection Using Infrared Thermal Imaging and a Deep Learning Model

scientific article published on 25 August 2018

Cardiomyopathy induced by T-2 toxin in rats

scientific article published on 22 January 2020

Chemical aspects of pharmacological prophylaxis against nerve agent poisoning.

scientific article published on January 2009

Chemical warfare agent NOVICHOK - mini-review of available data

scientific article published on 11 September 2018

Cholinesterase biosensor construction - a review.

scientific article published on January 2008

Chronic Exposure to Organophosphates Pesticides and Risk of Metabolic Disorder in Cohort from Pakistan and Cameroon

scientific article published in 2021

Chyawanprash: A Traditional Indian Bioactive Health Supplement.

scientific article published on 26 April 2019

Cognitive decline in normal aging and its prevention: a review on non-pharmacological lifestyle strategies

scientific article

Combined Pre- and Posttreatment of Paraoxon Exposure

scientific article published on 27 March 2020

Computational Enzymology and Organophosphorus Degrading Enzymes: Promising Approaches Toward Remediation Technologies of Warfare Agents and Pesticides

scientific article published on 21 February 2016

Concentration of Donepezil in the Cerebrospinal Fluid of AD Patients: Evaluation of Dosage Sufficiency in Standard Treatment Strategy

scientific article published on 07 October 2016

Condensed and hydrolysable tannins as antioxidants influencing the health

scientific article published on May 2008

Conifer-Derived Metallic Nanoparticles: Green Synthesis and Biological Applications

scientific article published on 27 November 2020

Consequences of chronic diseases and other limitations associated with old age - a scoping review

scientific article published on 01 November 2019

Design, evaluation and structure-activity relationship studies of the AChE reactivators against organophosphorus pesticides.

scientific article published on 21 December 2009

Detection of Bacterial Pathogens and Antibiotic Residues in Chicken Meat: A Review

scientific article published on 20 October 2020

Development and Structural Modifications of Cholinesterase Reactivators against Chemical Warfare Agents in Last Decade: A Review.

scientific article

Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy.

scientific article published on 28 July 2017

Development of new acetylcholinesterase reactivators: molecular modeling versus in vitro data

scientific article

Diagnosis of Intoxication by the Organophosphate VX: Comparison Between an Electrochemical Sensor and Ellman´s Photometric Method.

scientific article published on September 2008

Dose-response modeling of reactivating potency of oximes K027 and K203 against a direct acetylcholinesterase inhibitor in rat erythrocytes

scientific article published on 01 September 2018

E-learning as valuable caregivers' support for people with dementia - A systematic review

scientific article published on 01 November 2019

Effect Of An Extra-Virgin Olive Oil Intake On The Delay Of Cognitive Decline: Role Of Secoiridoid Oleuropein?

scientific article published on 29 October 2019

Effectiveness of the dog therapy for patients with dementia - a systematic review

scientific article published on 06 September 2019

Efficacy of methylprednisolone on T-2 toxin-induced cardiotoxicity in vivo: A pathohistological study

scientific article published on 19 July 2019

First Attempts of the Use of 195Pt NMR of Phenylbenzothiazole Complexes as Spectroscopic Technique for the Cancer Diagnosis

scientific article published on 02 November 2019

Flakka: New Dangerous Synthetic Cathinone on the Drug Scene

scientific article published on 31 October 2020

Flower-Based Green Synthesis of Metallic Nanoparticles: Applications beyond Fragrance

scientific article published on 16 April 2020

From hypoxia and hypoxia-inducible factors (HIF) to oxidative stress: A new understanding of the toxic mechanism of mycotoxins

scientific article published on 15 November 2019

From pyridinium-based to centrally active acetylcholinesterase reactivators

scientific article published on January 2014

Fruit Extract Mediated Green Synthesis of Metallic Nanoparticles: A New Avenue in Pomology Applications

scientific article published on 11 November 2020

Fruit and Vegetable Peels: Utilization of High Value Horticultural Waste in Novel Industrial Applications

scientific article published on 18 June 2020

Global View on Rare Diseases - a Mini Review

scientific article published on 10 May 2017

Glycosylated-imidazole aldoximes as reactivators of pesticides inhibited AChE: Synthesis and in-vitro reactivation study

scientific article published on 06 July 2020

Hybrid Materials Based on Magnetic Iron Oxides with Benzothiazole Derivatives: A Plausible Potential Spectroscopy Probe

scientific article published on 12 April 2021

Immune Evasion, a Potential Mechanism of Trichothecenes: New Insights into Negative Immune Regulations

scientific article published on 24 October 2018

In Vitro Evaluation of Neutral Aryloximes as Reactivators for Electrophorus eel Acetylcholinesterase Inhibited by Paraoxon

scientific article published on 08 October 2019

In silico pharmacophore model for tabun-inhibited acetylcholinesterase reactivators: a study of their stereoelectronic properties

scientific article

Innate Immune System and Multiple Sclerosis. Granulocyte Numbers Are Reduced in Patients Affected by Relapsing-Remitting Multiple Sclerosis during the Remission Phase

scientific article published on 14 May 2020

Insect Antimicrobial Peptides, a Mini Review

article

Interspecies and intergender differences in acute toxicity of K-oximes drug candidates

scientific article published on 31 May 2019

Investigation of New Orexin 2 Receptor Modulators Using and In Vitro Methods

scientific article published on 09 November 2018

JNK signaling in cancer cell survival

scientific article published on 25 March 2019

Ligand-Based Virtual Screening, Molecular Docking, Molecular Dynamics, and MM-PBSA Calculations towards the Identification of Potential Novel Ricin Inhibitors

scientific article published on 26 November 2020

Malus domestica: A Review on Nutritional Features, Chemical Composition, Traditional and Medicinal Value

scientific article published on 22 October 2020

Mechanism of cyclosporine A nephrotoxicity: Oxidative stress, autophagy, and signalings

scientific article published on 28 June 2018

Metabolic pathways of T-2 toxin

scientific article

Metabolic pathways of trichothecenes.

scientific article published on May 2010

Molecular Dynamics Simulation and Binding Free Energy Studies of Novel Leads Belonging to the Benzofuran Class Inhibitors of Mycobacterium tuberculosis Polyketide Synthase 13.

scientific article published on 10 April 2018

Molecular Modeling Studies on the Interactions of Aflatoxin B1 and Its Metabolites with Human Acetylcholinesterase. Part II: Interactions with the Catalytic Anionic Site (CAS)

scientific article published on 25 September 2018

Molecular Modeling and In Vitro Studies of a Neutral Oxime as a Potential Reactivator for Acetylcholinesterase Inhibited by Paraoxon

scientific article published on 12 November 2018

Molecular modeling studies on the interactions of 7-methoxytacrine-4-pyridinealdoxime, 4-PA, 2-PAM, and obidoxime with VX-inhibited human acetylcholinesterase: a near attack conformation approach

scientific article published on 01 December 2019

Molecular modeling studies on the interactions of aflatoxin B1 and its metabolites with the peripheral anionic site of human acetylcholinesterase

scientific article published on 02 November 2018

Multitarget drug design strategy: quinone-tacrine hybrids designed to block amyloid-β aggregation and to exert anticholinesterase and antioxidant effects

scientific article

Mycorrhiza Regulates Signal Substance Levels and Pathogen Defense Gene Expression to Resist Citrus Canker

scientific article published on 24 December 2019

Mycorrhizal inoculation impact on Acorus calamus L. - an ethnomedicinal plant of western Himalaya and its in silico studies for anti-inflammatory potential

scientific article published on 03 September 2020

Mycotoxin assays using biosensor technology: a review

scientific article published on January 2007

Non-Pharmacological Approaches to the Prevention and Treatment of Alzheimer's Disease with Respect to the Rising Treatment Costs

scientific article

Non-conventional compounds with potential therapeutic effects against Alzheimer's disease

scientific article published on 29 April 2019

Novel CRISPR-Cas Systems: An Updated Review of the Current Achievements, Applications, and Future Research Perspectives

publication published on 24 March 2021

Novel Group of AChE Reactivators-Synthesis, In Vitro Reactivation and Molecular Docking Study

scientific article published on 07 September 2018

Novel Tacrine-Scutellarin Hybrids as Multipotent Anti-Alzheimer's Agents: Design, Synthesis and Biological Evaluation.

scientific article

Novichoks: The Dangerous Fourth Generation of Chemical Weapons ⬇️

scientific article published on 11 March 2019

Orexin supplementation in narcolepsy treatment: A review

scientific article published on 14 November 2018

Outcomes of Alzheimer's disease therapy with acetylcholinesterase inhibitors and memantine.

scientific article published on June 2014

Oxidative Stress and Analysis of Selected SNPs of ACHE (rs 2571598), BCHE (rs 3495), CAT (rs 7943316), SIRT1 (rs 10823108), GSTP1 (rs 1695), and Gene GSTM1, GSTT1 in Chronic Organophosphates Exposed Groups from Cameroon and Pakistan

scientific article published on 03 September 2020

Oximes: inhibitors of human recombinant acetylcholinesterase. A structure-activity relationship (SAR) study

scientific article published on 16 August 2013

Plant Fortification of the Diet for Anti-Ageing Effects: A Review

scientific article published on 30 September 2020

Possible role of hydroxylated metabolites of tacrine in drug toxicity and therapy of Alzheimer's disease

scientific article published on May 2008

Predictions of Alzheimer's disease treatment and care costs in European countries

scientific article published in PLoS ONE

Profiling donepezil template into multipotent hybrids with antioxidant properties

scientific article published in December 2018

Progress of biosensors based on cholinesterase inhibition

scientific article published on January 2009

Prolyl oligopeptidase and its role in the organism: attention to the most promising and clinically relevant inhibitors

scientific article published on 20 June 2017

Protective Effects of Simvastatin on Endotoxin-Induced Acute Kidney Injury through Activation of Tubular Epithelial Cells' Survival and Hindering Cytochrome C-Mediated Apoptosis

scientific article published on 30 September 2020

Pyridinium oximes with ortho-positioned chlorine moiety exhibit improved physicochemical properties and efficient reactivation of human acetylcholinesterase inhibited by several nerve agents

scientific article published on 20 November 2018

QSAR Study of N-Myristoyltransferase Inhibitors of Antimalarial Agents

scientific article published on 13 September 2018

Rational Design of a New Class of Toll-Like Receptor 4 (TLR4) Tryptamine Related Agonists by Means of the Structure- and Ligand-Based Virtual Screening for Vaccine Adjuvant Discovery.

scientific article published on 4 January 2018

Reactivation of VX-Inhibited Human Acetylcholinesterase by Deprotonated Pralidoxime. A Complementary Quantum Mechanical Study

scientific article published on 27 January 2020

Red-Crowned Crane (Grus japonensis) Reproduction Was Improved by Inhibiting Mycotoxins with Montmorillonite in Feed

scientific article published on 18 March 2020

Resorcylic acid lactones as the protein kinase inhibitors , naturally occuring toxins

scientific article

Safety and Efficacy of New Oximes to Reverse Low Dose Diethyl-Paraoxon-Induced Ventilatory Effects in Rats

scientific article published on 03 July 2020

Searching for potential drugs against SARS-CoV-2 through virtual screening on several molecular targets

scientific article published on 08 January 2021

Semantic Dementia: A Mini-Review

scientific article published on 23 December 2016

Simvastatin Protects Cardiomyocytes Against Endotoxin-induced Apoptosis and Up-regulates Survivin/NF-κB/p65 Expression

scientific article published in Scientific Reports

Small Molecules Targeting Ataxia Telangiectasia and Rad3-Related (ATR) Kinase: An Emerging way to Enhance Existing Cancer Therapy

scientific article published in January 2016

Smart and Climate-Smart Agricultural Trends as Core Aspects of Smart Village Functions

scientific article published on 22 October 2020

Structural Properties of Potential Synthetic Vaccine Adjuvants - TLR Agonists.

scientific article published on 20 August 2015

Structural factors influencing potency of currently used acetylcholinesterase reactivators for treatment of cyclosarin intoxications

scientific article published on January 2007

Structural requirements of acetylcholinesterase reactivators.

scientific article

Surface screening, molecular modeling and in vitro studies on the interactions of aflatoxin M1 and human enzymes acetyl- and butyrylcholinesterase

scientific article published on 14 May 2019

Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators

scientific article published on 01 December 2020

Tacrine and its 7-methoxy derivate; time-change concentration in plasma and brain tissue and basic toxicological profile in rats

scientific article published on 01 July 2019

Targeting JNK and its role in tumor development and chemoresistance

scientific article published on 06 May 2020

The Efficacy of Amifostine against Multiple-Dose Doxorubicin-Induced Toxicity in Rats

scientific article published on 12 August 2018

The Puzzling Potential of Carbon Nanomaterials: General Properties, Application, and Toxicity

scientific article published on 31 July 2020

The development of ataxia telangiectasia mutated kinase inhibitors

scientific article published in January 2014

The development of new oximes and the evaluation of their reactivating, therapeutic and neuroprotective efficacy against tabun.

scientific article published on October 2008

The direct costs of multiple sclerosis-study in the Czech Republic

scientific article published on 03 September 2018

The history of poisoning: from ancient times until modern ERA

scientific article published on 21 August 2018

The potential of medical device industry in technological and economical context

scientific article

The progress in the cholinesterase quantification methods.

scientific article published on 26 September 2012

The role of hypoxia-inducible factor 1 in tumor immune evasion

scientific article published on 11 December 2020

The social and economic burden on family caregivers for older adults in the Czech Republic

scientific article published on 11 May 2020

Theoretical Studies Aimed at Finding FLT3 Inhibitors and a Promising Compound and Molecular Pattern with Dual Aurora B/FLT3 Activity

scientific article published on 09 April 2020

Treatment of organophosphate intoxication using cholinesterase reactivators: facts and fiction.

scientific article published on May 2007

Trends in the Recent Patent Literature on Cholinesterase Reactivators (2016-2019)

scientific article published on 12 March 2020

Trichothecenes: Structure-Toxic Activity Relationships ⬇️

scientific article published on July 1, 2013

Trithiocyanurate complexes of iron, manganese and nickel and their anticholinesterase activity.

scientific article published on 8 April 2014

Two-Step Mechanism of Cellular Uptake of Cationic Gold Nanoparticles Modified by (16-Mercaptohexadecyl)trimethylammonium Bromide

scientific article

Type A Trichothecene Diacetoxyscirpenol-Induced Emesis Corresponds to Secretion of Peptide YY and Serotonin in Mink

scientific article published on 25 June 2020

Understanding of Colistin Usage in Food Animals and Available Detection Techniques: A Review

scientific article published on 16 October 2020

Understanding the Interaction Modes and Reactivity of Trimedoxime toward MmAChE Inhibited by Nerve Agents: Theoretical and Experimental Aspects

scientific article published on 05 September 2020

Use of cloud computing in biomedicine

scientific article published on 08 December 2015

Vaccine Design from the Ensemble of Surface Glycoprotein Epitopes of SARS-CoV-2: An Immunoinformatics Approach

scientific article published on 28 July 2020

Vascular Cognitive Impairment: Information from Animal Models on the Pathogenic Mechanisms of Cognitive Deficits

scientific article published on 15 May 2019

Wide-Antimicrobial Spectrum of Picolinium Salts

scientific article published on 11 May 2020

Zinc-Based Nanomaterials for Diagnosis and Management of Plant Diseases: Ecological Safety and Future Prospects

scientific article published on 13 October 2020

Δ-FeOOH as Support for Immobilization Peroxidase: Optimization via a Chemometric Approach

scientific article published on 08 January 2020

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