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List of works by Nic Gillings

(99m)Tc-aprotinin - optimisation and validation of radiolabelling kits for routine preparation for diagnostic imaging of amyloidosis

scientific article published on 28 February 2016

18F-Labelling of electron rich iodonium ylides: application to the radiosynthesis of potential 5-HT2A receptor PET ligands.

scientific article published on 5 May 2017

5-HTTLPR status predictive of neocortical 5-HT4 binding assessed with [(11)C]SB207145 PET in humans

scientific article

A quartz-lined carbon-11 target: striving for increased yield and specific activity.

scientific article published on 20 September 2010

A restricted access material for rapid analysis of [(11)C]-labeled radiopharmaceuticals and their metabolites in plasma

scientific article published on 3 October 2009

Accelerating preclinical PET-screening: reductive amination with [11C]methoxybenzaldehydes

scholarly article in RSC Advances, vol. 4 no. 41, 2014

BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels

scientific article (publication date: 2015)

Binding characteristics of the 5-HT2A receptor antagonists altanserin and MDL 100907.

scientific article

Brain imaging of serotonin 4 receptors in humans with [11C]SB207145-PET.

scientific article

Comparison of [18F]FBA and [18F]FPyMe as peptide radiolabeling agents of PEPHC1 for PET imaging of EGFRvIII.

scientific article published in January 2009

Comparison of ultrafiltration and equilibrium dialysis for estimation of protein binding

Convergent 18F-labeling and evaluation of N-benzyl-phenethylamines as 5-HT2A receptor PET ligands

scientific article published on 29 August 2016

Direct comparison of [(18) F]MH.MZ and [(18) F] altanserin for 5-HT2A receptor imaging with PET.

scientific article published on 7 March 2013

Direct radiofluorination of [18F]MH.MZ for 5-HT2A receptor molecular imaging with PET

scholarly article by Matthias M. Herth et al published July 2012 in Journal of Labelled Compounds and Radiopharmaceuticals

EANM guidance document: dosimetry for first-in-human studies and early phase clinical trials

scientific article published on 17 February 2024

EANM guideline on the validation of analytical methods for radiopharmaceuticals

scientific article published on 12 February 2020

Efficient regioselective ring opening of activated aziridine-2-carboxylates with [(18)f]fluoride

scientific article published on 21 November 2014

Evaluation of 4-[18F]fluorobenzoyl-FALGEA-NH2 as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer.

scientific article published in March 2011

Evaluation of the novel 5-HT4 receptor PET ligand [11C]SB207145 in the Göttingen minipig

scientific article

Fluorine-18 labelling of a series of potential EGFRvIII targeting peptides with a parallel labelling approach using [18F]FPyME

article published in 2010

HPLC methods for the purification of [11C]-labelled radiopharmaceuticals: reversal of the retention order of products and precursors

Identification of amino acid residues in PEPHC1 important for binding to the tumor-specific receptor EGFRvIII.

scientific article published on October 2008

Identification of novel peptide ligands for the cancer-specific receptor mutation EFGRvIII using a mixture-based synthetic combinatorial library

scientific article

In Vivo Veritas: 18F-Radiolabeled Glycomimetics Allow Insights into the Pharmacological Fate of Galectin-3 Inhibitors

scientific article published on 03 January 2020

In vivo evaluation of a series of substituted 11C-phenetylamines as 5-HT2A agonist PET tracers

Kinetic modeling of 11C-SB207145 binding to 5-HT4 receptors in the human brain in vivo

scientific article

Kinetics of the metabolism of four PET radioligands in living minipigs

scientific article

Kinetics of the uptake and distribution of the dopamine D(2,3) agonist (R)-N-[1-(11)C]n-propylnorapomorphine in brain of healthy and MPTP-treated Göttingen miniature pigs

scientific article published in July 2003

Mass dose effects and in vivo affinity in brain PET receptor studies--a study of cerebral 5-HT4 receptor binding with [11C]SB207145.

scientific article published on 9 August 2011

Measuring endogenous changes in serotonergic neurotransmission with [C]Cimbi-36 positron emission tomography in humans

Metabolic Fate of Hallucinogenic NBOMes

scientific article published on 15 December 2015

No change in [¹¹C]CUMI-101 binding to 5-HT(1A) receptors after intravenous citalopram in human

scientific article published on 20 July 2012

Obesity is associated with high serotonin 4 receptor availability in the brain reward circuitry

scientific article

On the consensus nomenclature rules for radiopharmaceutical chemistry - Reconsideration of radiochemical conversion

scientific article published on 18 November 2020

Radiosynthesis and evaluation of 11C-CIMBI-5 as a 5-HT2A receptor agonist radioligand for PET.

scientific article

Radiosynthesis and ex vivo evaluation of (R)-(-)-2-chloro-N-[1-11C-propyl]n-propylnorapomorphine

scientific article published on 3 October 2009

Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT (2A) agonist PET tracers

scientific article

Radiotracers for positron emission tomography imaging

scientific article published on 16 December 2012

Serotonin 2A receptor agonist binding in the human brain with [(11)C]Cimbi-36: Test-retest reproducibility and head-to-head comparison with the antagonist [(18)F]altanserin

scientific article

Serotonin 2A receptor agonist binding in the human brain with [¹¹C]Cimbi-36.

scientific article

Simultaneous hyperpolarized (13)C-pyruvate MRI and (18)F-FDG-PET in cancer (hyperPET): feasibility of a new imaging concept using a clinical PET/MRI scanner

scientific article

Stress hormone dynamics are coupled to brain serotonin 4 receptor availability in unmedicated patients with Major Depressive Disorder – a NeuroPharm study

Synthesis and binding studies of 2-arylapomorphines

scientific article published on 13 October 2005

Synthesis and evaluation of (18)F-labeled 5-HT2A receptor agonists as PET ligands

scientific article published on 19 April 2016

The Center for Integrated Molecular Brain Imaging (Cimbi) database ⬇️

scientific article

The competition between endogenous dopamine and radioligands for specific binding to dopamine receptors

scientific article published in June 2002

The importance of small polar radiometabolites in molecular neuroimaging: A PET study with [11C]Cimbi-36 labeled in two positions

scientific article published in January 2017

Tracer-dose limits and in vivo 5-HT4 receptor affinity in human brain PET studies with [11C]SB207145

[(64) Cu]-labelled trastuzumab: optimisation of labelling by DOTA and NODAGA conjugation and initial evaluation in mice

scientific article published on 24 April 2015

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