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List of works by Sandhya Srikant Visweswariah

A Mycobacterial Cyclic AMP Phosphodiesterase That Moonlights as a Modifier of Cell Wall Permeability

scientific article

A fluorescent nucleic acid nanodevice quantitatively images elevated cyclic adenosine monophosphate in membrane-bound compartments

scientific article published on 14 July 2014

A structural basis for the role of nucleotide specifying residues in regulating the oligomerization of the Rv1625c adenylyl cyclase from M. tuberculosis

scientific article published on 22 December 2005

A survey of nucleotide cyclases in actinobacteria: unique domain organization and expansion of the class III cyclase family in Mycobacterium tuberculosis

scientific article

A universal stress protein (USP) in mycobacteria binds cAMP.

scientific article published on 23 March 2015

Absence of receptor guanylyl cyclase C enhances ileal damage and reduces cytokine and antimicrobial peptide production during oral Salmonella Typhimurium infection

scientific article published on 20 February 2018

Advantage of the ether linkage between the positive charge and the cholesteryl skeleton in cholesterol-based amphiphiles as vectors for gene delivery

scientific article published in March 2002

Allostery and Conformational Dynamics in cAMP-binding Acyltransferases

scientific article

Autoinhibitory mechanism and activity-related structural changes in a mycobacterial adenylyl cyclase

scientific article

Biopanning of endotoxin-specific phage displayed peptides

scientific article

Cellular refractoriness to the heat-stable enterotoxin peptide is associated with alterations in levels of the differentially glycosylated forms of guanylyl cyclase C.

scientific article

Characterization of an evolutionarily conserved metallophosphoesterase that is expressed in the fetal brain and associated with the WAGR syndrome

scientific article published on 12 November 2008

Characterization of phylogenetically distant members of the adenylate cyclase family from mycobacteria: Rv1647 from Mycobacterium tuberculosis and its orthologue ML1399 from M. leprae

scientific journal article

Class III nucleotide cyclases in bacteria and archaebacteria: lineage-specific expansion of adenylyl cyclases and a dearth of guanylyl cyclases

scientific article published in March 2004

Congenital secretory diarrhoea caused by activating germline mutations in GUCY2C.

scientific article published on 20 May 2015

Cross talk between receptor guanylyl cyclase C and c-src tyrosine kinase regulates colon cancer cell cytostasis

scientific article

Cyclic AMP in mycobacteria: characterization and functional role of the Rv1647 ortholog in Mycobacterium smegmatis

scientific article published on 04 April 2008

Cyclic AMP-induced conformational changes in mycobacterial protein acetyltransferases

scientific article

Cyclic nucleotide binding and structural changes in the isolated GAF domain of Anabaena adenylyl cyclase, CyaB2.

scientific article published on 23 April 2015

Cyclic nucleotide signaling in intestinal epithelia: getting to the gut of the matter

scientific article published on 22 April 2013

Defying the stereotype: non-canonical roles of the Peptide hormones guanylin and uroguanylin

scientific article published on 15 June 2011

Distinct allostery induced in the cyclic GMP-binding, cyclic GMP-specific phosphodiesterase (PDE5) by cyclic GMP, sildenafil, and metal ions

scientific article

Evolution of bacterial transcription factors: how proteins take on new tasks, but do not always stop doing the old ones

scientific article published on 20 May 2015

Expression of the receptor guanylyl cyclase C and its ligands in reproductive tissues of the rat: a potential role for a novel signaling pathway in the epididymis

scientific article (publication date: December 2002)

Familial diarrhea syndrome caused by an activating GUCY2C mutation.

scientific article

Genomic mapping of cAMP receptor protein (CRP Mt) in Mycobacterium tuberculosis: relation to transcriptional start sites and the role of CRPMt as a transcription factor

scientific article

Glycosylation of the receptor guanylate cyclase C: role in ligand binding and catalytic activity

scientific article

Guanylin, uroguanylin, and heat-stable euterotoxin activate guanylate cyclase C and/or a pertussis toxin-sensitive G protein in human proximal tubule cells

scientific article (publication date: 17 May 2002)

Histone deacetylases regulate multicellular development in the social amoeba Dictyostelium discoideum.

scientific article

Intestinal cell proliferation and senescence are regulated by receptor guanylyl cyclase C and p21.

scientific article

Linking carbon metabolism to carotenoid production in mycobacteria using Raman spectroscopy

article

Metallophosphoesterases: structural fidelity with functional promiscuity

scientific article published on April 2015

Modeling and mutational analysis of the GAF domain of the cGMP-binding, cGMP-specific phosphodiesterase, PDE5.

scientific article published in March 2003

Mutational analysis of the Mycobacterium tuberculosis Rv1625c adenylyl cyclase: residues that confer nucleotide specificity contribute to dimerization

scientific journal article

Mycobacterial adenylyl cyclases: biochemical diversity and structural plasticity

scientific article

Mycobacterial phenolic glycolipid synthesis is regulated by cAMP-dependent lysine acylation of FadD22.

scientific article published on 28 January 2017

Nanoscale dynamics of phospholipids reveals an optimal assembly mechanism of pore-forming proteins in bilayer membranes

scientific article published on 20 October 2016

New messages from old messengers: cAMP and mycobacteria

scientific article published on 19 October 2006

New structural forms of a mycobacterial adenylyl cyclase Rv1625c

scientific article

Overexpression of the Rv0805 phosphodiesterase elicits a cAMP-independent transcriptional response

scientific article published on 06 July 2013

Purification, crystallization and preliminary X-ray diffraction analysis of the catalytic domain of adenylyl cyclase Rv1625c from Mycobacterium tuberculosis

scientific article published on 23 January 2004

Receptor guanylyl cyclase C (GC-C): regulation and signal transduction

scientific article

Signaling via guanylyl cyclase C: cGMP, Src and p21.

scientific article published in August 2011

Signalling mechanisms in Mycobacteria

scientific article published on 13 May 2011

Site-directed mutagenesis using a single mutagenic oligonucleotide and DpnI digestion of template DNA.

scientific article

Site-specific N-linked glycosylation of receptor guanylyl cyclase C regulates ligand binding, ligand-mediated activation and interaction with vesicular integral membrane protein 36, VIP36.

scientific article

Structural and biochemical analysis of the Rv0805 cyclic nucleotide phosphodiesterase from Mycobacterium tuberculosis

scientific journal article

Substrate specificity determinants of class III nucleotidyl cyclases

scientific article

Super-resolution Stimulated Emission Depletion-Fluorescence Correlation Spectroscopy Reveals Nanoscale Membrane Reorganization Induced by Pore-Forming Proteins

scientific article published on 26 August 2016

The GAF domain of the cGMP-binding, cGMP-specific phosphodiesterase (PDE5) is a sensor and a sink for cGMP.

scientific article

The Rv0805 gene from Mycobacterium tuberculosis encodes a 3',5'-cyclic nucleotide phosphodiesterase: biochemical and mutational analysis

scientific journal article

The Solvent-Exposed C-Terminus of the Cytolysin A Pore-Forming Toxin Directs Pore Formation and Channel Function in Membranes

scientific article published on 29 September 2016

The ascent of nucleotide cyclases: conservation and evolution of a theme

scientific article published in March 2002

The cGMP-binding, cGMP-specific phosphodiesterase (PDE5): intestinal cell expression, regulation and role in fluid secretion

scientific article published in June 2004

The evolution of guanylyl cyclases as multidomain proteins: conserved features of kinase-cyclase domain fusions.

scientific article published on 3 June 2009

The kinase homology domain of receptor guanylyl cyclase C: ATP binding and identification of an adenine nucleotide sensitive site

scientific article published in February 2006

The linker region in receptor guanylyl cyclases is a key regulatory module: mutational analysis of guanylyl cyclase C

scientific article

The multiple and enigmatic roles of guanylyl cyclase C in intestinal homeostasis

scientific article published on 20 July 2012

The non-catalytic "cap domain" of a mycobacterial metallophosphoesterase regulates its expression and localization in the cell

scientific article

Tyrphostins are inhibitors of guanylyl and adenylyl cyclases

scientific article published on June 2004

Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome

scientific article

cAMP-regulated protein lysine acetylases in mycobacteria

scientific journal article

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