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List of works by Rentala Madhubala

A Heterologous Prime‐Boost Vaccination Regimen Using ORFF DNA and Recombinant ORFF Protein Confers Protective Immunity against Experimental Visceral Leishmaniasis

article by Poonam Tewary et al published 15 June 2005 in Journal of Infectious Diseases

A Plant like Cytochrome P450 Subfamily CYP710C1 Gene in Leishmania donovani Encodes Sterol C-22 Desaturase and its Over-expression Leads to Resistance to Amphotericin B

scientific article published on 03 April 2019

A glutathione-specific aldose reductase of Leishmania donovani and its potential implications for methylglyoxal detoxification pathway.

scientific article published on 15 October 2008

A quantitative proteomic screen to identify potential drug resistance mechanism in α-difluoromethylornithine (DFMO) resistant Leishmania donovani

scientific article published on 12 March 2014

A unique modification of the eukaryotic initiation factor 5A shows the presence of the complete hypusine pathway in Leishmania donovani

scientific article

Antileishmanial activity and modification of hepatic xenobiotic metabolizing enzymes in golden hamster by 2(3)-tert-butyl-4-hydroxyanisole following infection with Leishmania donovani

scientific article published on 01 January 1994

Antileishmanial activity of berenil and methylglyoxal bis (guanylhydrazone) and its correlation with S-adenosylmethionine decarboxylase and polyamines

scientific article published on 01 January 1995

Antileishmanial effect of 3-aminooxy-1-aminopropane is due to polyamine depletion

scientific article published on 13 November 2006

Antileishmanial effect of a potent S-adenosylmethionine decarboxylase inhibitor: CGP 40215A

scientific article published on 01 January 1996

Assessing aquaglyceroporin gene status and expression profile in antimony-susceptible and -resistant clinical isolates of Leishmania donovani from India

scientific article published on 12 January 2010

Biochemical, mutational and in silico structural evidence for a functional dimeric form of the ornithine decarboxylase from Entamoeba histolytica

scientific article

Characterization and localization of ORFF gene from the LD1 locus of Leishmania donovani.

scientific article published on 26 January 2008

Characterization of Leishmania donovani aquaporins shows presence of subcellular aquaporins similar to tonoplast intrinsic proteins of plants

scientific article

Characterization of alpha-difluoromethylornithine resistant Leishmania donovani and its susceptibility to other inhibitors of the polyamine biosynthetic pathway

scientific article published on 01 July 1996

Characterization of the Entamoeba histolytica ornithine decarboxylase-like enzyme

scientific article

Characterization of the gene encoding glyoxalase II from Leishmania donovani: a potential target for anti-parasite drugs

scientific article published on January 2006

Cholesterol is required for Leishmania donovani infection: implications in leishmaniasis

scientific article published on February 2004

Co-administration of IL-12 DNA with rORFF antigen confers long-term protective immunity against experimental visceral leishmaniaisis

scientific article published in 2006

Combined action of inhibitors of polyamine biosynthetic pathway with a known antimalarial drug chloroquine on plasmodium falciparum ⬇️

scientific article published on March 1, 1995

Cryptosporidium parvum has an active hypusine biosynthesis pathway

scientific article

Deletion of Vitamin C biosynthesis enzyme, Arabino-1, 4-lactone oxidase in Leishmania donovani results in increased pro-inflammatory responses from host immune cells

scientific article published on 21 February 2014

Desensitization of ornithine decarboxylase activity to norepinephrine in the testis of rat

scientific article published on 01 March 1984

Differential expression of proteins in antimony-susceptible and -resistant isolates of Leishmania donovani

scientific article published on 25 June 2011

Drug targets in Leishmania

scientific article published on April 2010

Effect of a bis(benzyl)polyamine analogue, and DL-alpha-difluoromethylornithine on parasite suppression and cellular polyamine levels in golden hamster during Leishmania donovani infection

scientific article published on 01 December 1993

Effect of antioxidants on the growth and polyamine levels of Leishmania donovani

scientific article published on 01 February 1994

Effect of prostaglandins on ornithine decarboxylase activity in the testis of immature rat

scientific article published on 01 September 1980

Effects of bis(benzyl)polyamine analogs on Leishmania donovani promastigotes

scientific article published on 01 August 1995

Expression of biopterin transporter (BT1) protein in Leishmania

scientific article

Genetic Validation of Leishmania donovani Lysyl-tRNA Synthetase Shows that It Is Indispensable for Parasite Growth and Infectivity

scientific article published on July 2017

Genetic manipulation of Leishmania donovani threonyl tRNA synthetase facilitates its exploration as a potential therapeutic target.

scientific article published on 13 June 2018

Genetically Engineered Ascorbic acid-deficient Live Mutants of Leishmania donovani induce long lasting Protective Immunity against Visceral Leishmaniasis.

scientific article published on 2 June 2015

Glyoxalase I from Leishmania donovani: a potential target for anti-parasite drug

scientific article published on 7 October 2005

Glyoxalase I gene deletion mutants of Leishmania donovani exhibit reduced methylglyoxal detoxification

scientific article

Glyoxalase pathway of trypanosomatid parasites: a promising chemotherapeutic target

scientific article

Identification and characterization of a novel deoxyhypusine synthase in Leishmania donovani

scientific article

Identification and functional characterization of a novel bacterial type asparagine synthetase A: a tRNA synthetase paralog from Leishmania donovani

scientific article

Immunization with recombinant LD1 antigens protects against experimental leishmaniasis

scientific article published on 15 October 2000

Immunostimulatory oligodeoxynucleotides are potent enhancers of protective immunity in mice immunized with recombinant ORFF leishmanial antigen.

scientific article

In the human malaria parasite Plasmodium falciparum, polyamines are synthesized by a bifunctional ornithine decarboxylase, S-adenosylmethionine decarboxylase

scientific article (publication date: 17 March 2000)

Inhibition of epinephrine and gonadotropic hormone induced ornithine decarboxylase activity by phenoxybenzamine in the testis of immature rat

scientific article published on 01 February 1983

Inhibition of ornithine decarboxylase and S-adenosylmethionine decarboxylase synthesis by antisense oligodeoxynucleotides

scientific article published on 01 December 1992

Leishmania donovani Encodes a Functional Selenocysteinyl-tRNA Synthase.

scientific article

Leishmania donovani activates nuclear transcription factor-kappaB in macrophages through reactive oxygen intermediates

scientific article published on September 2004

Leishmania donovani encodes a functional enzyme involved in vitamin C biosynthesis: arabino-1,4-lactone oxidase

scientific article published on 3 September 2011

Leishmania donovani induces interferon regulatory factor in murine macrophages: a host defense response

scientific article published on April 2004

Leishmania donovani: Characterization and Expression of ORFF, a Gene Amplified from the LDI Locus

scientific article published in December 1999

Leishmania donovani: cellular control of ornithine decarboxylase in promastigotes

scientific article published on 01 September 1995

Leishmania genome analysis and high-throughput immunological screening identifies tuzin as a novel vaccine candidate against visceral leishmaniasis

scientific article published on 9 May 2014

Leishmania lipophosphoglycan activates the transcription factor activating protein 1 in J774A.1 macrophages through the extracellular signal-related kinase (ERK) and p38 mitogen-activated protein kinase.

scientific article

Leishmaniasis: current status of vaccine development

scientific article published in September 2004

MicroRNA expression profiling of Leishmania donovani-infected host cells uncovers the regulatory role of MIR30A-3p in host autophagy.

scientific article published on 26 July 2016

Novel agmatine analogue, gamma-guanidinooxypropylamine (GAPA) efficiently inhibits proliferation of Leishmania donovani by depletion of intracellular polyamine levels

scientific article published on 8 August 2008

Novel arylimidamides for treatment of visceral leishmaniasis

scientific article

Novel convenient synthesis of biologically active esters of hydroxylamine

scientific article published on 8 December 2009

Paromomycin affects translation and vesicle-mediated trafficking as revealed by proteomics of paromomycin -susceptible -resistant Leishmania donovani

scientific article

Paromomycin: uptake and resistance in Leishmania donovani.

scientific article published on 25 December 2008

Proteomic-based approach to gain insight into reprogramming of THP-1 cells exposed to Leishmania donovani over an early temporal window

scientific article

Quantitative proteomic profiling of the promastigotes and the intracellular amastigotes of Leishmania donovani isolates identifies novel proteins having a role in Leishmania differentiation and intracellular survival

scientific article

Role of ABC transporter MRPA, gamma-glutamylcysteine synthetase and ornithine decarboxylase in natural antimony-resistant isolates of Leishmania donovani.

scientific article published on 9 January 2007

Roles for mitochondria in pentamidine susceptibility and resistance in Leishmania donovani.

scientific article

Stimulation of ornithine decarboxylase activity by prostaglandins in the isolated cells of immature rat testis

scientific article published on 01 December 1980

Structural Insight into DFMO Resistant Ornithine Decarboxylase from Entamoeba histolytica: An Inkling to Adaptive Evolution

scientific article

The mitochondrial SIR2 related protein 2 (SIR2RP2) impacts Leishmania donovani growth and infectivity

scientific article

The sterol-binding antibiotic nystatin inhibits entry of non-opsonized Leishmania donovani into macrophages

scientific article published on 18 November 2005

Twin Attributes of Tyrosyl-tRNA Synthetase of Leishmania donovani: A HOUSEKEEPING PROTEIN TRANSLATION ENZYME AND A MIMIC OF HOST CHEMOKINE.

scientific article published on 5 July 2016

Ubiquitin conjugation of open reading frame F DNA vaccine leads to enhanced cell-mediated immune response and induces protection against both antimony-susceptible and -resistant strains of Leishmania donovani

scientific article published in December 2009

Unique posttranslational modifications in eukaryotic translation factors and their roles in protozoan parasite viability and pathogenesis

scientific article

Unusual domain architecture of aminoacyl tRNA synthetases and their paralogs from Leishmania major

scientific article

Vaccination with DNA encoding ORFF antigen confers protective immunity in mice infected with Leishmania donovani

scientific article published on 01 March 2003

Vaccination with Leishmania soluble antigen and immunostimulatory oligodeoxynucleotides induces specific immunity and protection against Leishmania donovani infection

scientific article published on 01 October 2004

Visceral and post-Kala-Azar dermal leishmaniasis isolates show significant difference in their in vitro drug susceptibility pattern

scientific article published on 18 December 2012

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