List of works - Hediye Erdjument-Bromage

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

scientific article (publication date: November 2002)

SNAP receptors implicated in vesicle targeting and fusion

scientific article (publication date: 25 March 1993)

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

scientific article

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

scientific article

PRDM16 controls a brown fat/skeletal muscle switch

scientific article

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

scientific article

Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein

scientific article

Histone demethylation by a family of JmjC domain-containing proteins

scientific article

Role of histone H2A ubiquitination in Polycomb silencing

scientific article

DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

scientific article

Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis

scientific article (publication date: 22 April 2005)

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

scientific article

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

scientific article

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

scientific journal article

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

scientific journal article

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR

scientific journal article

RSC, an essential, abundant chromatin-remodeling complex

scientific article

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.

scientific article

Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin

scientific article

JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor

scientific article

Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain

scientific journal article

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

scientific article (publication date: September 1999)

Ubiquitination regulates PTEN nuclear import and tumor suppression

scientific article

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex

scientific article

Histone deimination antagonizes arginine methylation

scientific article

Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex

scientific article

A human telomeric protein

scientific article

NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

scientific article

Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing

scientific article published on November 2007

Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair

scientific article published on December 2002

COMPASS: a complex of proteins associated with a trithorax-related SET domain protein

scientific article

Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation

scientific article

PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin

scientific journal article

The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36.

scientific article

Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes

scientific article

An iron delivery pathway mediated by a lipocalin

scientific article (publication date: November 2002)

The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

scientific journal article

Differential exoprotease activities confer tumor-specific serum peptidome patterns

scientific article published in January 2006

Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association

scientific article

A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme

scientific article

P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

scientific article

Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation

scientific article

Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage

scientific article (publication date: 5 May 2006)

The retinoblastoma binding protein RBP2 is an H3K4 demethylase

scientific article published on 22 February 2007

A Drosophila Polycomb group complex includes Zeste and dTAFII proteins

scientific article published in August 2001

SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation

scientific article

PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation

scientific article published on 15 March 2007

Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex

scientific journal article

PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox

article

Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia

scientific article

List of works by Hediye Erdjument-Bromage

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

SNAP receptors implicated in vesicle targeting and fusion

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

PRDM16 controls a brown fat/skeletal muscle switch

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein

Histone demethylation by a family of JmjC domain-containing proteins

Role of histone H2A ubiquitination in Polycomb silencing

DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR

RSC, an essential, abundant chromatin-remodeling complex

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.

Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin

JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor

Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

Ubiquitination regulates PTEN nuclear import and tumor suppression

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex

Histone deimination antagonizes arginine methylation

Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex

A human telomeric protein

NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing

Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair

COMPASS: a complex of proteins associated with a trithorax-related SET domain protein

Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation

PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin

The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36.

Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes

An iron delivery pathway mediated by a lipocalin

The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

Differential exoprotease activities confer tumor-specific serum peptidome patterns

Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association

A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme

P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation

Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage

The retinoblastoma binding protein RBP2 is an H3K4 demethylase

A Drosophila Polycomb group complex includes Zeste and dTAFII proteins

SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation

PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation

Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex

PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox

Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia