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List of works by Melvyn Greaves

A causal mechanism for childhood acute lymphoblastic leukaemia.

scientific article

Acquisition of genome-wide copy number alterations in monozygotic twins with acute lymphoblastic leukemia

scientific article published on 08 January 2010

Acute lymphoblastic leukaemia

scientific article

Allergy and risk of childhood leukaemia: results from the UKCCS.

scientific article published in August 2007

Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia

scientific article published in Nature Communications

Backtracking of leukemic clones to birth

scientific article published on January 2009

Cancer causation: the Darwinian downside of past success?

scientific article

Cancer cell transmission via the placenta.

scientific article published on 14 April 2018

Cancer stem cells as ‘units of selection’ ⬇️

scientific article published on October 23, 2012

Cancer stem cells: back to Darwin?

scientific article published on 30 March 2010

Cancer's Darwinian dilemma: an evolutionary tale in three acts

scientific article

Childhood leukaemia

scientific article

Chromosome translocations and covert leukemic clones are generated during normal fetal development

scientific article

Classifying the evolutionary and ecological features of neoplasms

scientific article published on 15 September 2017

Clonal evolution in cancer

scientific article (publication date: 18 January 2012)

Clonal expansion in B-CLL: Fungal drivers or self-service? ⬇️

scientific article published on January 14, 2013

Clonal origins of ETV6-RUNX1⁺ acute lymphoblastic leukemia: studies in monozygotic twins.

scientific article

Common genetic variation contributes significantly to the risk of childhood B-cell precursor acute lymphoblastic leukemia

scientific article published on 29 March 2012

Covert preleukemia driven by MLL gene fusion

scientific article published in January 2009

Darwin and evolutionary tales in leukemia. The Ham-Wasserman Lecture

scientific article

Darwinian medicine: a case for cancer

scientific article published on 15 February 2007

Developmental impact of leukemic fusion genes on stem cell fate

scientific article

Developmental origins and impact of BCR-ABL1 fusion and IKZF1 deletions in monozygotic twins with Ph+ acute lymphoblastic leukemia

scientific article published on 29 September 2011

Developmental timing of mutations revealed by whole-genome sequencing of twins with acute lymphoblastic leukemia

scientific article

Directing oncogenic fusion genes into stem cells via an SCL enhancer

scientific article

Does everyone develop covert cancer?

scientific article published on 01 April 2014

ETV6-RUNX1 + Acute Lymphoblastic Leukaemia in Identical Twins

scientific article published on January 2017

Enforced expression of MLL-AF4 fusion in cord blood CD34+ cells enhances the hematopoietic repopulating cell function and clonogenic potential but is not sufficient to initiate leukemia

scientific article published on 9 March 2011

Erratum: Corrigendum: Signatures of mutational processes in human cancer

scientific article published in Nature

Evolutionary Adaptations to Risk of Cancer: Evidence From Cancer Resistance in Elephants

scientific article

Evolutionary determinants of cancer

scientific article (publication date: August 2015)

Fetal origins of the TEL-AML1 fusion gene in identical twins with leukemia ⬇️

scientific article published on April 14, 1998

Fusion genes in cord blood ⬇️

scientific article published on January 6, 2011

Genetic and functional diversity of propagating cells in glioblastoma

scientific article

Genetic lesions in a preleukemic aplasia phase in a child with acute lymphoblastic leukemia

scientific article published on April 2008

Genetic variegation of clonal architecture and propagating cells in leukaemia

scientific article published on 15 December 2010

Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia ⬇️

scientific article published on 9 April 2018

Genome-wide homozygosity signatures and childhood acute lymphoblastic leukemia risk

Godwits and blast crises: in memory of David Galton

scientific article published in December 2007

Identification of preleukemic precursors of hyperdiploid acute lymphoblastic leukemia in cord blood

scientific article published on May 2004

Immunologically silent cancer clone transmission from mother to offspring

scientific article

In utero origin of t(8;21) AML1-ETO translocations in childhood acute myeloid leukemia

scientific article published in May 2002

In utero origins of childhood leukaemia

scientific article

Infection and the Perils of B-cell Activation

scientific article published on December 2015

Infection, immune responses and the aetiology of childhood leukaemia

scientific article

Initiating and cancer-propagating cells in TEL-AML1-associated childhood leukemia

scientific article published in January 2008

Leukaemia 'firsts' in cancer research and treatment

scientific article published on February 2016

Leukemogenesis and ageing: ‘fit for transformation’ ? ⬇️

scientific article published on February 1, 2011

Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia

scientific article

MHC variation and risk of childhood B-cell precursor acute lymphoblastic leukemia

MLL chimeric protein activation renders cells vulnerable to chromosomal damage: an explanation for the very short latency of infant leukemia

scientific article published on August 2006

Modeling first-hit functions of the t(12;21) TEL-AML1 translocation in mice

scholarly article

Molecular pathogenesis of MLL-associated leukemias

scientific article

NOTCH1 mutation can be an early, prenatal genetic event in T-ALL.

scientific article published on 27 September 2007

Nothing in cancer makes sense except….

scientific article published on 21 February 2018

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

scientific article

P-24: a human leukemia-associated and lymphohemopoietic progenitor cell surface structure identified with monoclonal antibody

scientific article

Pre-natal origins of childhood leukemia.

scientific article published on September 2003

Pre-natal, clonal origin of acute lymphoblastic leukaemia in triplets

scientific article published on December 2003

Processed pseudogenes acquired somatically during cancer development

scientific article published on 09 April 2014

Protracted dormancy of pre-leukemic stem cells

scientific article

Protracted postnatal natural histories in childhood leukemia

scientific article

RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia

scientific article

Rationale for an international consortium to study inherited genetic susceptibility to childhood acute lymphoblastic leukemia

scientific article

Retrospective. Janet Rowley (1925-2013).

scientific article

Role of the TEL-AML1 fusion gene in the molecular pathogenesis of childhood acute lymphoblastic leukaemia

scientific article published on May 2004

Single-cell mutational profiling and clonal phylogeny in cancer

scientific article published on 20 September 2013

Specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia.

scientific article

The 9p21.3 risk of childhood acute lymphoblastic leukaemia is explained by a rare high-impact variant in CDKN2A ⬇️

scientific article

The TEL-AML1 leukemia fusion gene dysregulates the TGF-beta pathway in early B lineage progenitor cells

scientific article published on 16 March 2009

The association of a distinctive allele of NAD(P)H:quinone oxidoreductase with pediatric acute lymphoblastic leukemias with MLL fusion genes in Japan.

scientific article published in November 2005

The histone deacetylase 9 gene encodes multiple protein isoforms

scientific article

The role of the MLL gene in infant leukemia

scientific article

The small oligomerization domain of gephyrin converts MLL to an oncogene

scientific article published on 29 January 2004

The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia.

scientific article published on 20 March 2018

Tyrosine kinase inhibitor insensitivity of non-cycling CD34+ human acute myeloid leukaemia cells with FMS-like tyrosine kinase 3 mutations

scientific article published on 21 June 2011

Ubiquitous cell-surface glycoprotein on tumor cells is proliferation-associated receptor for transferrin ⬇️

scientific article published on July 1, 1981

Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype

scientific journal article

Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk

scientific article

Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood

scientific article

Was skin cancer a selective force for black pigmentation in early hominin evolution?

scientific article published on 26 February 2014

When one mutation is all it takes

scientific article

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