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Authors whose works are in public domain in at least one jurisdiction

List of works by Leemor Joshua-Tor

A structural model for sequence-specific proflavin-DNA interactions during in vitro frameshift mutagenesis

scientific article published on October 1, 1992

A structural snapshot of base-pair opening in DNA

scientific article

A structural view of the initiators for chromosome replication

scientific article published on 12 September 2018

A triple helix stabilizes the 3' ends of long noncoding RNAs that lack poly(A) tails

scientific article

Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi

scientific article

Ancestral roles of small RNAs: an Ago-centric perspective

scientific article published on October 2011

Argonaute MID domain takes centre stage

scientific article

Argonaute and RNA--getting into the groove

scientific article

Argonaute slicing is required for heterochromatic silencing and spreading

scientific article

Argonaute2 is the catalytic engine of mammalian RNAi

scientific article (publication date: 3 September 2004)

Argonautes confront new small RNAs

scientific article

CRL4-like Clr4 complex in Schizosaccharomyces pombe depends on an exposed surface of Dos1 for heterochromatin silencing

scientific article

Chd5 requires PHD-mediated histone 3 binding for tumor suppression

scientific journal article

Comparison of the X-ray structure of native rubredoxin from Pyrococcus furiosus with the NMR structure of the zinc-substituted protein ⬇️

scientific article published on November 1, 1992

Conformational variability in structures of the nitrogenase iron proteins from Azotobacter vinelandii and Clostridium pasteurianum

scientific article

Crystal structure of Apaf-1 caspase recruitment domain: an alpha-helical Greek key fold for apoptotic signaling

scientific article

Crystal structure of Argonaute and its implications for RISC slicer activity

scientific article (publication date: 3 September 2004)

Crystal structure of carboxypeptidase A complexed with D-cysteine at 1.75 A - inhibitor-induced conformational changes

scientific article

Crystal structure of human bleomycin hydrolase, a self-compartmentalizing cysteine protease

scientific article

Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex

scientific article

Decoding the 5' nucleotide bias of PIWI-interacting RNAs

article

Dynamic look at DNA unwinding by a replicative helicase.

scientific article published on 18 February 2014

Engineering photocycle dynamics. Crystal structures and kinetics of three photoactive yellow protein hinge-bending mutants

scientific article

Essential Dynamics from NMR Clusters: Dynamic Properties of the Myb DNA-Binding Domain and a Hinge-Bending Enhancing Variant ⬇️

scientific article published on March 1, 1998

Eukaryotic Argonautes come into focus

scientific article published on 29 March 2013

Evolution of DNA replication origin specification and gene silencing mechanisms

scientific article published on 14 October 2020

FUS Regulates Activity of MicroRNA-Mediated Gene Silencing.

scientific article published in March 2018

From guide to target: molecular insights into eukaryotic RNA-interference machinery.

scientific article published on January 2015

Harnessing insulin- and leptin-induced oxidation of PTP1B for therapeutic development

scientific article published on 18 January 2018

High-Affinity Binding of Chp1 Chromodomain to K9 Methylated Histone H3 Is Required to Establish Centromeric Heterochromatin

scientific article

High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations

scientific article published on 10 June 2019

Mechanism of DNA translocation in a replicative hexameric helicase

scientific article published on July 2006

Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway

scientific journal article

Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis

scientific article published on 3 July 2017

Multivalent Recruitment of Human Argonaute by GW182.

scientific article published on 21 July 2017

Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure

scientific article published on January 2007

NADP Regulates the Yeast GAL Induction System

scientific article

NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler.

scientific article

Noncysteinyl coordination to the [4Fe-4S]2+ cluster of the DNA repair adenine glycosylase MutY introduced via site-directed mutagenesis. Structural characterization of an unusual histidinyl-coordinated cluster

scientific article

On helicases and other motor proteins

scientific article published on 10 March 2008

On-enzyme refolding permits small RNA and tRNA surveillance by the CCA-adding enzyme

scientific article

PTEN functions by recruitment to cytoplasmic vesicles

scientific article published on 9 April 2015

Purified Argonaute2 and an siRNA form recombinant human RISC

scientific article (publication date: April 2005)

Rapid generation of drug-resistance alleles at endogenous loci using CRISPR-Cas9 indel mutagenesis.

scientific article

Selective chemical inactivation of AAA proteins reveals distinct functions of proteasomal ATPases

scientific article

Slicer and the argonautes

scientific article published on January 2007

Strategies for protein coexpression in Escherichia coli

scientific article published in January 2006

Structural basis for the EBA-175 erythrocyte invasion pathway of the malaria parasite Plasmodium falciparum

scientific article published in July 2005

Structurally modulated codelivery of siRNA and Argonaute 2 for enhanced RNA interference

scientific article published on 5 February 2018

Structure of the active form of human origin recognition complex and its ATPase motor module

scientific article published on 23 January 2017

Structure of the photoactive yellow protein reconstituted with caffeic acid at 1.16 A resolution

scientific article

Structure of the photoactive yellow protein reconstituted with caffeic acid at 1.16 Å resolution

article by Daan M. F. van Aalten et al published 22 March 2002 in Acta Crystallographica Section D: Biological Crystallography

Target binding triggers hierarchical phosphorylation of human Argonaute-2 to promote target release

scientific article published on 31 May 2022

The Chp1–Tas3 core is a multifunctional platform critical for gene silencing by RITS

scientific article

The DNA-binding domain of human papillomavirus type 18 E1. Crystal structure, dimerization, and DNA binding

scientific article

The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation

scientific article

The Making of a Slicer: Activation of Human Argonaute-1

scientific article

The Structure of Human Argonaute-2 in Complex with miR-20a

scientific article

The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes

scientific article

The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis

scientific article

The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase

scientific article

Three-dimensional structures of bulge-containing DNA fragments

scientific article

X-ray crystal structures of the oxidized and reduced forms of the rubredoxin from the marine hyperthermophilic archaebacterium Pyrococcus furiosus ⬇️

scientific article published on November 1, 1992

siRNA carrying an (E)-vinylphosphonate moiety at the 5΄ end of the guide strand augments gene silencing by enhanced binding to human Argonaute-2.

scientific article

siRNAs at RISC.

scientific article published in July 2004

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