List of works - Randi J. Hagerman

A new look at XXYY syndrome: medical and psychological features

scientific article

A randomized double-blind, placebo-controlled trial of minocycline in children and adolescents with fragile x syndrome

scientific article published on April 2013

A review of fragile X premutation disorders: expanding the psychiatric perspective

scientific article

A solution to limitations of cognitive testing in children with intellectual disabilities: the case of fragile X syndrome

scientific article published on March 2009

Abnormal N400 word repetition effects in fragile X-associated tremor/ataxia syndrome

scientific article

Abnormal nerve conduction features in fragile X premutation carriers

scientific article

Advances in the Understanding of the Gabaergic Neurobiology of FMR1 Expanded Alleles Leading to Targeted Treatments for Fragile X Spectrum Disorder

scientific article

Advances in the treatment of fragile X syndrome

scientific article

Age-Dependent Structural Connectivity Effects in Fragile X Premutation ⬇️

scientific article published on April 1, 2012

Aging in fragile X syndrome.

scientific article

Alcohol use dependence in fragile X syndrome

scientific article published on August 2016

Anxiety disorders in fragile X premutation carriers: Preliminary characterization of probands and non-probands

scientific article

Arbaclofen in fragile X syndrome: results of phase 3 trials

scientific article

Autoimmune disease in mothers with the FMR1 premutation is associated with seizures in their children with fragile X syndrome

scientific article

Blood-Based Biomarkers Predictive of Metformin Target Engagement in Fragile X Syndrome

scientific article published on 10 June 2020

Broad clinical involvement in a family affected by the fragile X premutation

scientific article

CGG allele size somatic mosaicism and methylation in FMR1 premutation alleles

scientific article

Clinical assessment of DSM-IV anxiety disorders in fragile X syndrome: prevalence and characterization ⬇️

scientific article published on December 3, 2010

Cognitive, anxiety and mood disorders in the fragile X-associated tremor/ataxia syndrome

scientific article

Covariate adjusted correlation analysis with application to FMR1 premutation female carrier data

scientific article

Detection of skewed X-chromosome inactivation in Fragile X syndrome and X chromosome aneuploidy using quantitative melt analysis

scientific article published on July 2015

Developmental aspects of FXAND in a man with the FMR1 premutation

scientific article published on 03 January 2020

Double Genetic Hit: Fragile X Syndrome and Partial Deletion of Protein Patched Homolog 1 Antisense as Cause of Severe Autism Spectrum Disorder

scientific article published on 15 September 2020

Early detection of fragile X syndrome: applications of a novel approach for improved quantitative methylation analysis in venous blood and newborn blood spots

scientific article published on 28 April 2014

Effect of the mGluR5-NAM Basimglurant on Behavior in Adolescents and Adults with Fragile X Syndrome in a Randomized, Double-Blind, Placebo-Controlled Trial: FragXis Phase 2 Results.

scientific article

Electrocortical changes associated with minocycline treatment in fragile X syndrome.

scientific article

Emotion potentiated startle in fragile X syndrome

scientific article

Epilepsy drives autism in neurodevelopmental disorders

scientific article

Evaluation of the neuroactive steroid ganaxolone on social and repetitive behaviors in the BTBR mouse model of autism

scientific article

Evidence of mitochondrial dysfunction in fragile X-associated tremor/ataxia syndrome

scientific article

FMR1 CGG allele size and prevalence ascertained through newborn screening in the United States

scientific article

FMR1 premutation with Prader-Willi phenotype and fragile X-associated tremor/ataxia syndrome.

scientific article

FRAGILE X SYNDROME: PSYCHIATRIC MANIFESTATIONS, ASSESSMENT AND EMERGING THERAPIES

scientific article

Fibroblast phenotype in male carriers of FMR1 premutation alleles

scientific article

Fragile X Syndrome and Targeted Treatment Trials ⬇️

scientific article published on January 1, 2012

Fragile X Syndrome in a Colombian Family

Fragile X Syndrome: Prevalence, Treatment, and Prevention in China

scientific article

Fragile X associated neuropsychiatric disorders in a male without FXTAS

scientific article published on 01 May 2020

Fragile X mental retardation 1 (FMR1) intron 1 methylation in blood predicts verbal cognitive impairment in female carriers of expanded FMR1 alleles: evidence from a pilot study.

scientific article published on 10 January 2012

Fragile X premutation tremor/ataxia syndrome: molecular, clinical, and neuroimaging correlates

scientific article

Fragile X syndrome

2014 scientific article

Fragile X syndrome and fragile X-associated disorders.

scientific article published on 8 December 2017

Fragile X targeted pharmacotherapy: lessons learned and future directions

scientific article

Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS): Pathophysiology and Clinical Implications

scientific article published on 20 June 2020

Fragile X-associated tremor/ataxia syndrome

scientific article

Fragile X-associated tremor/ataxia syndrome (FXTAS).

scientific article

Fragile X-associated tremor/ataxia syndrome: clinical features, genetics, and testing guidelines

scientific article

Fragile X-associated tremor/ataxia syndrome: influence of the FMR1 gene on motor fiber tracts in males with normal and premutation alleles.

scientific article

Fragile X-related element 2 methylation analysis may provide a suitable option for inclusion of fragile X syndrome and/or sex chromosome aneuploidy into newborn screening: a technical validation study

scientific article

Fragile X: a family of disorders

scientific article

Fragile X: leading the way for targeted treatments in autism

scientific article

Fragile x syndrome

2011 scientific article

Genetic cluster of fragile X syndrome in a Colombian district

scientific article

Group I metabotropic glutamate receptor mediated dynamic immune dysfunction in children with fragile X syndrome

scientific article

Improving fragile X-associated tremor/ataxia syndrome symptoms with memantine and venlafaxine

scientific article

Increased prevalence of seizures in boys who were probands with the FMR1 premutation and co-morbid autism spectrum disorder.

scientific article

Influence of the fragile X mental retardation (FMR1) gene on the brain and working memory in men with normal FMR1 alleles

scientific article published on 12 October 2012

Investigation of amygdala volume in men with the fragile X premutation.

scientific article published on December 2011

Lifetime prevalence of mood and anxiety disorders in fragile X premutation carriers

scientific article

Memantine effects on verbal memory in fragile X-associated tremor/ataxia syndrome (FXTAS): a double-blind brain potential study

scientific article

Metformin treatment in young children with fragile X syndrome

scientific article published on 14 September 2019

Molecular and cognitive predictors of the continuum of autistic behaviours in fragile X

scientific article

Neural progenitor cells from an adult patient with fragile X syndrome

scientific article

Neural substrates of executive dysfunction in fragile X-associated tremor/ataxia syndrome (FXTAS): a brain potential study

scientific article

Parkinsonism in fragile X-associated tremor/ataxia syndrome (FXTAS): revisited

scientific article

Penetrance of the fragile X-associated tremor/ataxia syndrome in a premutation carrier population

scientific article (publication date: 28 January 2004)

Phenobarbital use and neurological problems in FMR1 premutation carriers

scientific article

Plasma cytokine profiles in Fragile X subjects: is there a role for cytokines in the pathogenesis?

scientific article published on 25 January 2010

Premutation in the Fragile X Mental Retardation 1 (FMR1) Gene Affects Maternal Zn-milk and Perinatal Brain Bioenergetics and Scaffolding

scientific article published on 19 April 2016

Prepulse inhibition in fragile X syndrome: feasibility, reliability, and implications for treatment

scientific article

Prepulse inhibition in patients with fragile X-associated tremor ataxia syndrome

scientific article

Psychiatric symptoms in boys with fragile X syndrome: a comparison with nonsyndromic autism spectrum disorder

scientific article

Reduced Hippocampal Activation During Recall is Associated with Elevated FMR1 mRNA and Psychiatric Symptoms in Men with the Fragile X Premutation.

scientific article published on January 2008

Reduced excitatory amino acid transporter 1 and metabotropic glutamate receptor 5 expression in the cerebellum of fragile X mental retardation gene 1 premutation carriers with fragile X-associated tremor/ataxia syndrome

scientific article

Relationships between age and epi-genotype of the FMR1 exon 1/intron 1 boundary are consistent with non-random X-chromosome inactivation in FM individuals, with the selection for the unmethylated state being most significant between birth and pubert

scientific article

Response to Placebo in Fragile X Syndrome Clinical Trials: An Initial Analysis

scientific article published on 11 September 2020

Robust Machine Learning-Based Correction on Automatic Segmentation of the Cerebellum and Brainstem

scientific article

Sequencing the unsequenceable: expanded CGG-repeat alleles of the fragile X gene

scientific article

Side effects of minocycline treatment in patients with fragile X syndrome and exploration of outcome measures

scientific article

Sleep apnea in fragile X premutation carriers with and without FXTAS ⬇️

scientific article published on September 19, 2011

Testing the FMR1 promoter for mosaicism in DNA methylation among CpG sites, strands, and cells in FMR1-expressing males with fragile X syndrome

scientific article

The Autism Spectrum Disorders Stem Cell Resource at Children's Hospital of Orange County: Implications for Disease Modeling and Drug Discovery

scientific article

The Gut Microbiota and Autism Spectrum Disorders

scientific article

The fragile-X premutation: a maturing perspective

scientific article

The primary cognitive deficit among males with fragile X-associated tremor/ataxia syndrome (FXTAS) is a dysexecutive syndrome.

scientific article

Treatment of neurodevelopmental disorders in adulthood

scientific article

List of works by Randi J. Hagerman

A new look at XXYY syndrome: medical and psychological features

A randomized double-blind, placebo-controlled trial of minocycline in children and adolescents with fragile x syndrome

A review of fragile X premutation disorders: expanding the psychiatric perspective

A solution to limitations of cognitive testing in children with intellectual disabilities: the case of fragile X syndrome

Abnormal N400 word repetition effects in fragile X-associated tremor/ataxia syndrome

Abnormal nerve conduction features in fragile X premutation carriers

Advances in the Understanding of the Gabaergic Neurobiology of FMR1 Expanded Alleles Leading to Targeted Treatments for Fragile X Spectrum Disorder

Advances in the treatment of fragile X syndrome

Age-Dependent Structural Connectivity Effects in Fragile X Premutation ⬇️

Aging in fragile X syndrome.

Alcohol use dependence in fragile X syndrome

Anxiety disorders in fragile X premutation carriers: Preliminary characterization of probands and non-probands

Arbaclofen in fragile X syndrome: results of phase 3 trials

Autoimmune disease in mothers with the FMR1 premutation is associated with seizures in their children with fragile X syndrome

Blood-Based Biomarkers Predictive of Metformin Target Engagement in Fragile X Syndrome

Broad clinical involvement in a family affected by the fragile X premutation

CGG allele size somatic mosaicism and methylation in FMR1 premutation alleles

Clinical assessment of DSM-IV anxiety disorders in fragile X syndrome: prevalence and characterization ⬇️

Cognitive, anxiety and mood disorders in the fragile X-associated tremor/ataxia syndrome

Covariate adjusted correlation analysis with application to FMR1 premutation female carrier data

Detection of skewed X-chromosome inactivation in Fragile X syndrome and X chromosome aneuploidy using quantitative melt analysis

Developmental aspects of FXAND in a man with the FMR1 premutation

Double Genetic Hit: Fragile X Syndrome and Partial Deletion of Protein Patched Homolog 1 Antisense as Cause of Severe Autism Spectrum Disorder

Early detection of fragile X syndrome: applications of a novel approach for improved quantitative methylation analysis in venous blood and newborn blood spots

Effect of the mGluR5-NAM Basimglurant on Behavior in Adolescents and Adults with Fragile X Syndrome in a Randomized, Double-Blind, Placebo-Controlled Trial: FragXis Phase 2 Results.

Electrocortical changes associated with minocycline treatment in fragile X syndrome.

Emotion potentiated startle in fragile X syndrome

Epilepsy drives autism in neurodevelopmental disorders

Evaluation of the neuroactive steroid ganaxolone on social and repetitive behaviors in the BTBR mouse model of autism

Evidence of mitochondrial dysfunction in fragile X-associated tremor/ataxia syndrome

FMR1 CGG allele size and prevalence ascertained through newborn screening in the United States

FMR1 premutation with Prader-Willi phenotype and fragile X-associated tremor/ataxia syndrome.

FRAGILE X SYNDROME: PSYCHIATRIC MANIFESTATIONS, ASSESSMENT AND EMERGING THERAPIES

Fibroblast phenotype in male carriers of FMR1 premutation alleles

Fragile X Syndrome and Targeted Treatment Trials ⬇️

Fragile X Syndrome in a Colombian Family

Fragile X Syndrome: Prevalence, Treatment, and Prevention in China

Fragile X associated neuropsychiatric disorders in a male without FXTAS

Fragile X mental retardation 1 (FMR1) intron 1 methylation in blood predicts verbal cognitive impairment in female carriers of expanded FMR1 alleles: evidence from a pilot study.

Fragile X premutation tremor/ataxia syndrome: molecular, clinical, and neuroimaging correlates

Fragile X syndrome

Fragile X syndrome and fragile X-associated disorders.

Fragile X targeted pharmacotherapy: lessons learned and future directions

Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS): Pathophysiology and Clinical Implications

Fragile X-associated tremor/ataxia syndrome

Fragile X-associated tremor/ataxia syndrome (FXTAS).

Fragile X-associated tremor/ataxia syndrome: clinical features, genetics, and testing guidelines

Fragile X-associated tremor/ataxia syndrome: influence of the FMR1 gene on motor fiber tracts in males with normal and premutation alleles.

Fragile X-related element 2 methylation analysis may provide a suitable option for inclusion of fragile X syndrome and/or sex chromosome aneuploidy into newborn screening: a technical validation study

Fragile X: a family of disorders

Fragile X: leading the way for targeted treatments in autism

Fragile x syndrome

Genetic cluster of fragile X syndrome in a Colombian district

Group I metabotropic glutamate receptor mediated dynamic immune dysfunction in children with fragile X syndrome

Improving fragile X-associated tremor/ataxia syndrome symptoms with memantine and venlafaxine

Increased prevalence of seizures in boys who were probands with the FMR1 premutation and co-morbid autism spectrum disorder.

Influence of the fragile X mental retardation (FMR1) gene on the brain and working memory in men with normal FMR1 alleles

Investigation of amygdala volume in men with the fragile X premutation.

Lifetime prevalence of mood and anxiety disorders in fragile X premutation carriers

Memantine effects on verbal memory in fragile X-associated tremor/ataxia syndrome (FXTAS): a double-blind brain potential study

Metformin treatment in young children with fragile X syndrome

Molecular and cognitive predictors of the continuum of autistic behaviours in fragile X

Neural progenitor cells from an adult patient with fragile X syndrome

Neural substrates of executive dysfunction in fragile X-associated tremor/ataxia syndrome (FXTAS): a brain potential study

Parkinsonism in fragile X-associated tremor/ataxia syndrome (FXTAS): revisited

Penetrance of the fragile X-associated tremor/ataxia syndrome in a premutation carrier population

Phenobarbital use and neurological problems in FMR1 premutation carriers

Plasma cytokine profiles in Fragile X subjects: is there a role for cytokines in the pathogenesis?

Premutation in the Fragile X Mental Retardation 1 (FMR1) Gene Affects Maternal Zn-milk and Perinatal Brain Bioenergetics and Scaffolding

Prepulse inhibition in fragile X syndrome: feasibility, reliability, and implications for treatment

Prepulse inhibition in patients with fragile X-associated tremor ataxia syndrome

Psychiatric symptoms in boys with fragile X syndrome: a comparison with nonsyndromic autism spectrum disorder

Reduced Hippocampal Activation During Recall is Associated with Elevated FMR1 mRNA and Psychiatric Symptoms in Men with the Fragile X Premutation.

Reduced excitatory amino acid transporter 1 and metabotropic glutamate receptor 5 expression in the cerebellum of fragile X mental retardation gene 1 premutation carriers with fragile X-associated tremor/ataxia syndrome

Relationships between age and epi-genotype of the FMR1 exon 1/intron 1 boundary are consistent with non-random X-chromosome inactivation in FM individuals, with the selection for the unmethylated state being most significant between birth and pubert

Response to Placebo in Fragile X Syndrome Clinical Trials: An Initial Analysis

Robust Machine Learning-Based Correction on Automatic Segmentation of the Cerebellum and Brainstem

Sequencing the unsequenceable: expanded CGG-repeat alleles of the fragile X gene

Side effects of minocycline treatment in patients with fragile X syndrome and exploration of outcome measures