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List of works by Eva Klein

A polymorphism within the connective tissue growth factor (CTGF) gene has no effect on non-invasive markers of beta-cell area and risk of type 2 diabetes

scientific article published on January 2011

Activation of innate immunity by the leukotriene B 4 inhibits EBV induced B-cell transformation in cord-blood derived mononuclear cultures

scientific article published on 10 January 2008

Association of AHSG Gene Polymorphisms With Fetuin-A Plasma Levels and Cardiovascular Diseases in the EPIC-Potsdam Study

article

Association of acyl-CoA-binding protein (ACBP) single nucleotide polymorphisms and type 2 diabetes in two German study populations

scientific article

Association of prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism with type 2 diabetes in two German study populations

scientific article

Association of the FTO rs9939609 single nucleotide polymorphism with C-reactive protein levels

scientific article published on 23 October 2008

Body mass index and C-174G interleukin-6 promoter polymorphism interact in predicting type 2 diabetes

scientific article published in April 2004

Carbazole is a naturally occurring inhibitor of angiogenesis and inflammation isolated from antipsoriatic coal tar.

scientific article

Concomitant increase of LMP1 and CD25 (IL-2-receptor alpha) expression induced by IL-10 in the EBV-positive NK lines SNK6 and KAI3.

scientific article published on December 2006

Cytokine mediated induction of the major Epstein-Barr virus (EBV)-encoded transforming protein, LMP-1.

scientific article

Cytomegalovirus-seropositive children show inhibition of in vitro EBV infection that is associated with CD8+CD57+ T cell enrichment and IFN-γ.

scientific article published on 18 October 2013

Deficiency of the proapoptotic SAP function in X-linked lymphoproliferative disease aggravates Epstein-Barr virus (EBV) induced mononucleosis and promotes lymphoma development

scientific article published on 18 January 2010

EBV infection induces expression of the transcription factors ATF-2/c-Jun in B lymphocytes but not in B-CLL cells

scientific article

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Evidence for the Thr79Met polymorphism of the ileal fatty acid binding protein (FABP6) to be associated with type 2 diabetes in obese individuals

scientific article published on 11 August 2009

Expression of SH2D1A in five classical Hodgkin's disease-derived cell lines

scientific article published on 01 May 2003

Genetic evidence of assortative mating in humans

scholarly article

Genetic variation in genes of the fatty acid synthesis pathway and breast cancer risk

scientific article published on 28 February 2009

Heterogeneity of the Stearoyl-CoA desaturase-1 (SCD1) gene and metabolic risk factors in the EPIC-Potsdam study

scientific article

IL-10 can induce the expression of EBV-encoded latent membrane protein-1 (LMP-1) in the absence of EBNA-2 in B lymphocytes and in Burkitt lymphoma- and NK lymphoma-derived cell lines

scientific article published on 6 December 2005

IL-21 imposes a type II EBV gene expression on type III and type I B cells by the repression of C- and activation of LMP-1-promoter

scientific article

In vitro EBV-infected subline of KMH2, derived from Hodgkin lymphoma, expresses only EBNA-1, while CD40 ligand and IL-4 induce LMP-1 but not EBNA-2.

scientific article

Interaction of Epstein-Barr virus (EBV) with human B-lymphocytes

scientific article published on May 2010

Interferon γ is a strong, STAT1-dependent direct inducer of BCL6 expression in multiple myeloma cells

scientific article published on 3 March 2018

KCNJ11 E23K Affects Diabetes Risk and Is Associated With the Disposition Index: Results of two independent German cohorts

article

L-FABP T94A is associated with fasting triglycerides and LDL-cholesterol in women

scientific article published on 7 May 2007

Lack of association between the tagging SNP A+930-->G of SOCS3 and type 2 diabetes mellitus: meta-analysis of four independent study populations

scientific article

Large-scale hypomethylated blocks associated with Epstein-Barr virus-induced B-cell immortalization

scientific article published on 25 September 2013

Latency Type-Dependent Modulation of Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Expression by Type I Interferons in B Cells ⬇️

scientific article published on February 15, 2012

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?

scientific article published on 23 October 2009

Microsomal triglyceride transfer protein -164 T > C gene polymorphism and risk of cardiovascular disease: results from the EPIC-Potsdam case-cohort study

scientific article

Monocytes enhance cell proliferation and LMP1 expression of nasal natural killer/T‐cell lymphoma cells by cell contact‐dependent interaction through membrane‐bound IL‐15 ⬇️

scientific article published on May 25, 2011

PSK and Trx80 inhibit B-cell growth in EBV-infected cord blood mononuclear cells through T cells activated by the monocyte products IL-15 and IL-12.

scientific article published on 26 October 2004

Polymorphisms of genes coding for ghrelin and its receptor in relation to anthropometry, circulating levels of IGF-I and IGFBP-3, and breast cancer risk: a case-control study nested within the European Prospective Investigation into Cancer and Nutri

scientific article published on 28 March 2008

Polymorphisms within insulin-degrading enzyme (IDE) gene determine insulin metabolism and risk of type 2 diabetes

scientific article

Putative association between a new polymorphism in exon 3 (Arg109Cys) of the pancreatic colipase gene and type 2 diabetes mellitus in two independent Caucasian study populations

scientific article

Restricted expression of EBV encoded proteins in in vitro infected CLL cells ⬇️

scientific article published on October 27, 2010

SH2D1A expression in Burkitt lymphoma cells is restricted to EBV positive group I lines and is downregulated in parallel with immunoblastic transformation

scientific article published in August 2002

SH2D1A expression reflects activation of T and NK cells in cord blood lymphocytes infected with EBV and treated with the immunomodulator PSK

scientific article (publication date: March 2002)

STAT6 signaling pathway activated by the cytokines IL-4 and IL-13 induces expression of the Epstein-Barr virus–encoded protein LMP-1 in absence of EBNA-2: implications for the type II EBV latent gene expression in Hodgkin lymphoma ⬇️

scientific article published on September 27, 2010

Significant associations of the rs2943634 (2q36.3) genetic polymorphism with adiponectin, high density lipoprotein cholesterol and ischemic stroke ⬇️

scientific article published on December 20, 2011

Simultaneous detection of the two main proliferation driving EBV encoded proteins, EBNA-2 and LMP-1 in single B cells

scientific article published on 18 August 2012

Soluble factors produced by activated CD4+T cells modulate EBV latency ⬇️

scientific article published on January 17, 2012

Surveillance against tumors--is it mainly immunological?

scientific article

T cells modulate Epstein-Barr virus latency phenotypes during infection of humanized mice

scientific article

The MEC1 and MEC2 lines represent two CLL subclones in different stages of progression towards prolymphocytic leukemia

scientific article

The X-linked lymphoproliferative disease gene product SAP is expressed in activated T and NK cells.

scientific article

The apoptosis modulating role of SAP (SLAM associated protein) contributes to the symptomatology of the X linked lymphoproliferative disease

The proapoptotic function of SAP provides a clue to the clinical picture of X-linked lymphoproliferative disease

scientific article published on July 2009

The role of DNA hypomethylation, histone acetylation and in vivo protein-DNA binding in Epstein-Barr virus-induced CD23 upregulation

scientific article published on 10 April 2013

To the genesis of Burkitt lymphoma: regulation of apoptosis by EBNA-1 and SAP may determine the fate of Ig-myc translocation carrying B lymphocytes

scientific article published on 27 October 2009

Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups

scientific journal article

Type I interferons directly down-regulate BCL-6 in primary and transformed germinal center B cells: Differential regulation in B cell lines derived from endemic or sporadic Burkitt’s lymphoma ⬇️

scientific article published on December 26, 2011

Upregulation of LMP1 expression by histone deacetylase inhibitors in an EBV carrying NPC cell line

scientific article published on January 2004

Vitamin D receptor and calcium sensing receptor polymorphisms and the risk of colorectal cancer in European populations

scientific article published on 25 August 2009

cMyc-p53 feedback mechanism regulates the dynamics of T lymphocytes in the immune response

scientific article published on 17 March 2016

p53 contributes to T cell homeostasis through the induction of pro-apoptotic SAP ⬇️

scientific article published on November 19, 2012

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