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List of works by Elaine Tuomanen

: Invasion and Inflammation ⬇️

scholarly article by Allister J Loughran et al published March 2019 in Microbiology Spectrum

A Cross-Reactive Protein Vaccine Combined with PCV-13 Prevents Streptococcus pneumoniae- and Haemophilus influenzae-Mediated Acute Otitis Media

scientific article published on 19 September 2019

A Multicenter Consortium to Define the Epidemiology and Outcomes of Inpatient Respiratory Viral Infections in Pediatric Hematopoietic Stem Cell Transplant Recipients.

scientific article published in July 2017

A Perfect Storm: Increased Colonization and Failure of Vaccination Leads to Severe Secondary Bacterial Infection in Influenza Virus-Infected Obese Mice

scientific article published on 19 September 2017

A cardioprotective role for platelet-activating factor through NOS-dependent S-nitrosylation

scientific article published on 25 April 2008

A live-attenuated pneumococcal vaccine elicits CD4+ T-cell dependent class switching and provides serotype independent protection against acute otitis media

scientific article published on January 2014

A sandwich adhesion on Streptococcus pneumoniae attaching to human oropharyngeal epithelial cells in vitro

scientific article published on April 1988

A spoonful of sugar to control inflammation?

scientific article published on March 1994

A structure-activity relationship for induction of meningeal inflammation by muramyl peptides

scientific article

Acute Bacterial Meningitis: Challenges to Better Antibiotic Therapy

scientific article published on 03 July 2019

Adapting a diet from sugar to meat: double-dealing genes of Streptococcus pyogenes

article

AdcAII of Streptococcus pneumoniae Affects Pneumococcal Invasiveness ⬇️

scientific article published on 11 January 2016

Adherence of Bordetella pertussis to Human Respiratory Epithelial Cells

scientific article published on 01 July 1983

Adhesion of microbial pathogens to leukocyte integrins: methods to study ligand mimicry

scientific article published on January 1995

Adjunctive Therapy of Experimental Meningitis: Agents Other than Steroids1

Adjuncts to the therapy of bacterial meningitis

scientific article published in 1990

Advances in the diagnosis and management of bacterial meningitis

Antibiotic tolerance among clinical isolates of bacteria

scientific article

Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus

scientific article

Assessment of molecular typing methods to determine invasiveness and to differentiate clones of Streptococcus pneumoniae ⬇️

scientific article (publication date: December 2007)

Attachment factors of Bordetella pertussis: mimicry of eukaryotic cell recognition molecules

scientific article

Autolysis-resistant peptidoglycan of anomalous composition in amino-acid-starved Escherichia coli

scientific article

Bacterial Interactions with Mucosal Epithelial Cells

Bacterial Interactions with Mucosal Epithelial Cells

Bacterial Peptidoglycan Transverses the Placenta to Induce Fetal Neuroproliferation and Aberrant Postnatal Behavior

scientific article

Bacterial Peptidoglycan Traverses the Placenta to Induce Fetal Neuroproliferation and Aberrant Postnatal Behavior

scientific article published on 01 June 2016

Bacterial inhibition of phosphatidylcholine synthesis triggers apoptosis in the brain

scientific article

Biology of Adhesins of Bordetella Pertussis: Integrins, Selectins, and Mimicry of Leukocyte Adherence to Endothelia

Blood borne: bacterial components in mother's blood influence fetal development

scientific article published on January 2016

Breaching the blood-brain barrier

scientific article

Broadly protective protein-based pneumococcal vaccine composed of pneumolysin toxoid-CbpA peptide recombinant fusion protein

scientific article published on 16 September 2013

Caging and COM-Bating Antibiotic Resistance

scientific article published on 01 April 2020

Calcium efflux is essential for bacterial survival in the eukaryotic host

scientific article published on 29 August 2008

Can microbial pathogenesis team up with immunology?

scientific article published on 01 December 1995

Capsular expression in Streptococcus pneumoniae negatively affects spontaneous and antibiotic-induced lysis and contributes to antibiotic tolerance

scientific article

Catecholamine norepinephrine diminishes lung epithelial cell adhesion of Streptococcus pneumoniae by binding iron

scientific article published on 20 August 2013

Cell wall-mediated neuronal damage in early sepsis

scientific article

Cellular damage in bacterial meningitis: an interplay of bacterial and host driven toxicity

scientific article published on 8 January 2007

Cephalosporin-resistant pneumococci and sickle cell disease

scientific article published on August 2005

Changes in peptidoglycan composition and penicillin-binding proteins in slowly growing Escherichia coli

scientific article

Characterization of Two Adhesins of Bordetella pertussis for Human Ciliated Respiratory-Epithelial Cells

scientific article published on 01 July 1985

Control of virulence by small RNAs in Streptococcus pneumoniae

scientific article published in 2012

Convergence of regulatory networks on the pilus locus of Streptococcus pneumoniae

scientific article published on 28 April 2008

Coordinate regulation of beta-lactamase induction and peptidoglycan composition by the amp operon

scientific article

Correlation Between the Interval of Influenza Virus Infectivity and Results of Diagnostic Assays in a Ferret Model.

scientific article

Cytokine secretion requires phosphatidylcholine synthesis

scientific article published on June 2008

Cytokine secretion requires phosphatidylcholine synthesis

Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells

article

Development of anti-adhesion carbohydrate drugs for clinical use.

scientific article published on January 1996

Dissecting Bacterial Cell Wall Entry and Signaling in Eukaryotic Cells: an Actin-Dependent Pathway Parallels Platelet-Activating Factor Receptor-Mediated Endocytosis.

scientific article published on 03 January 2017

Divergence in the background: hard to measure but the key to being the best of the best

scientific article published on 01 July 1999

Dual Phases of Apoptosis in Pneumococcal Meningitis

scientific article published on 03 November 2004

Dynamic capsule restructuring by the main pneumococcal autolysin LytA in response to the epithelium

scientific article published on 29 February 2016

Early biofilm formation on microtiter plates is not correlated with the invasive disease potential of Streptococcus pneumoniae

scientific article

Effect of thalidomide on the inflammatory response in cerebrospinal fluid in experimental bacterial meningitis

scientific article published on 01 October 1995

Emu-BCL10 mice exhibit constitutive activation of both canonical and noncanonical NF-kappaB pathways generating marginal zone (MZ) B-cell expansion as a precursor to splenic MZ lymphoma

scientific article published on 20 August 2009

Entry of pathogens into the central nervous system

scientific article published on July 1996

Entry of pathogens into the central nervous system

scientific article published in 1996

Exogenous remodeling of lung resident macrophages protects against infectious consequences of bone marrow-suppressive chemotherapy

scientific article published on 26 September 2016

Extracellular targeting of choline-binding proteins in Streptococcus pneumoniae by a zinc metalloprotease

scientific article published on April 2000

Genomic analyses of pneumococci from children with sickle cell disease expose host-specific bacterial adaptations and deficits in current interventions

scientific article

Gut Microbiome Composition Predicts Infection Risk during Chemotherapy in Children with Acute Lymphoblastic Leukemia.

scientific article

Hearing loss and pneumococcal meningitis: an animal model

scientific article published in December 1991

Host cell invasion by Streptococcus pneumoniae

scientific article

Host-pathogen interactions in bacterial meningitis

scientific article

Hydroxyurea therapy of a murine model of sickle cell anemia inhibits the progression of pneumococcal disease by down-modulating E-selectin

scientific article

Hypersusceptibility to Invasive Pneumococcal Infection in Experimental Sickle Cell Disease Involves Platelet‐Activating Factor Receptor

scientific article published on 08 January 2007

INTRACELLULAR UPTAKE OF PNEUMOCOCCAL CELL WALL DEPRESSES CONTRACTILITY

Identification of a Candidate Streptococcus pneumoniae core genome and regions of diversity correlated with invasive pneumococcal disease

scientific article

Induction of Pulmonary Inflammation by Components of the Pneumococcal Cell Surface1–2

scientific article published on 01 April 1987

Induction of autolysis in nongrowing Escherichia coli

scientific article

Induction of meningeal inflammation by diverse bacterial cell walls

scientific article published on 01 December 1986

Influence of neutropenia on the course of serotype 8 pneumococcal pneumonia in mice

scientific article published on 12 February 2007

Inhibition of T cells provides protection against early invasive pneumococcal disease

scientific article

Inhibition of the binding of penicillin to the pneumococcal penicillin-binding proteins (PBPs) by exogenous cell wall peptides

scientific article

Initiation of Bacterial Killing by Two-Component Sensing of a “Death Peptide”

Innate sensors for Gram-positive bacteria

scientific article

Interactions of bacteria with leukocyte integrins.

scientific article

Interplay of pneumococcal hydrogen peroxide and host-derived nitric oxide

scientific article published on September 2006

Intravenous zanamivir for oseltamivir-resistant 2009 H1N1 influenza

scientific article published on 23 December 2009

Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models

scientific article

Lectin domains in the toxin of Bordetella pertussis: selectin mimicry linked to microbial pathogenesis.

scientific article published on December 1994

MICROBIOLOGY: Appreciating Our Usual Guests

scientific article published in Science

Mechanisms of antibiotic resistance and tolerance in Streptococcus pneumoniae

scientific article

Mediators of inflammation and the treatment of bacterial meningitis

Microarray analysis of pneumococcal gene expression during invasive disease

scientific article published on October 2004

Mini-Review: Bioactivities of Bacterial Cell Envelopes in the Central Nervous System

scientific article published on 26 October 2020

Models of pneumococcal disease

Modulation of bacteriolysis by cooperative effects of penicillin-binding proteins 1a and 3 in Escherichia coli

scientific article published on November 1986

Molecular analysis of antibiotic tolerance in pneumococci

scientific article

Molecular and Cellular Biology of Pneumococcal Infection

article

Molecular and cellular mechanisms for microbial entry into the CNS.

scientific article

Molecular and cellular mechanisms of pneumococcal meningitis

scientific article published on October 1996

Molecular mechanisms of inflammation in experimental pneumococcal meningitis

scholarly article by Elaine Tuomanen published December 1987 in Pediatric Infectious Disease Journal

Molecular mechanisms of inflammation in experimental pneumococcal meningitis

scholarly article by Elaine Tuomanen published December 1987 in Pediatric Infectious Disease Journal

Multifunctional role of choline binding protein G in pneumococcal pathogenesis

scientific article

Multivalent Pneumococcal Protein Vaccines Comprising Pneumolysoid with Epitopes/Fragments of CbpA and/or PspA Elicit Strong and Broad Protection

scientific article

NMR assignment of the R2 domain of pneumococcal choline binding protein A (CbpA).

scientific article published in May 2005

Neural Targeting of Mycobacterium leprae Mediated by the G Domain of the Laminin-α2 Chain

scientific article published on 01 March 1997

Neuroprotection by a caspase inhibitor in acute bacterial meningitis

scientific article published on March 1999

New Insights into Recombinant Pertussis Toxin

New antibodies as adjunctive therapies for Gram-positive bacterial meningitis

scientific article published on December 1989

New insight on the pathogenesis and treatment of pneumococcal meningitis

Newly made enzymes determine ongoing cell wall synthesis and the antibacterial effects of cell wall synthesis inhibitors

scientific article

Noninvasive monitoring of pneumococcal meningitis and evaluation of treatment efficacy in an experimental mouse model.

scientific article published in April 2005

Nonsteroidal Anti-Inflammatory Agents in the Therapy for Experimental Pneumococcal Meningitis

scientific article published on 01 May 1987

Oligosaccharides interfere with the establishment and progression of experimental pneumococcal pneumonia.

scientific article published on September 1997

Opening the OPK Assay Gatekeeper: Harnessing Multi-Modal Protection by Pneumococcal Vaccines

scientific article published on 23 October 2019

Oral chloramphenicol in the treatment of Haemophilus influenzae meningitis

scientific article published on 01 December 1981

Organ-specific models of Streptococcus pneumoniae disease

scientific article published in January 2003

PAf receptor anchors Streptococcus pneumoniae to activated human endothelial cells

scientific article published on January 1996

PGRPs kill with an ancient weapon

scientific article

PNEUMOCOCCAL-INDUCED MYOCARDIAL DYSFUNCTION: THE ROLE OF PLATELET ACTIVATING FACTOR RECEPTOR (PAFR) AND THE PHOSPHOLIPASE C (PLC) PATHWAY

Partner drugs: a new outlook for bacterial meningitis

scientific article published on November 1988

Pathogenesis of Pneumococcal Infection

article

Pathogenesis of pneumococcal inflammation: otitis media.

scientific article published in December 2000

Penicillin-binding protein 7 and its relationship to lysis of nongrowing Escherichia coli.

scientific article

Peptides from pertussis toxin interfere with neutrophil adherence in vitro and counteract inflammation in vivo

scientific article published on 01 March 1994

Perspective of a Pediatrician: Shared Pathogenesis of the Three Most Successful Pathogens of Children

scientific article published on 15 October 2020

Perspective: targeting nitric oxide in the adjuvant therapy of sepsis and meningitis.

scientific article published on March 1998

Phenotypic Tolerance Of Bacteria

Phenotypic tolerance: the search for beta-lactam antibiotics that kill nongrowing bacteria

scientific article

Placebo-controlled double-blind evaluation of trimethoprim-sulfamethoxazole treatment of Yersinia enterocolitica gastroenteritis

scientific article published on February 1984

Planning and implementation of an infection control training program for healthcare providers in Latin America

scientific article published on 22 October 2007

Platelet-activating factor receptor and innate immunity: uptake of gram-positive bacterial cell wall into host cells and cell-specific pathophysiology.

scientific article published in November 2006

Pneumococcal Infections

article

Pneumococcal Invasion

scholarly article published 2015

Pneumococcal Surface Protein A Plays a Major Role in Streptococcus pneumoniae-Induced Immunosuppression

scientific article published on 30 March 2016

Pneumococcal cell wall activates NF-kappa B in human monocytes: aspects distinct from endotoxin.

scientific article published on May 1996

Pneumococcal licD2 gene is involved in phosphorylcholine metabolism.

scientific article

Pneumococcal neuraminidase activates TGF-β signalling

scientific article published on 28 July 2017

Pneumococcal pathogenesis: "innate invasion" yet organ-specific damage

scientific article published on 17 February 2010

Pneumococcal pneumolysin and H(2)O(2) mediate brain cell apoptosis during meningitis

scientific journal article

Pneumococcal pneumolysin and H2O2 mediate brain cell apoptosis during meningitis

Pneumococcal trafficking across the blood-brain barrier. Molecular analysis of a novel bidirectional pathway ⬇️

scientific article published on July 15, 1998

Pneumolysin: Pathogenesis and Therapeutic Target

scientific article published on 02 July 2020

Preinfection systemic inflammatory markers and risk of hospitalization due to pneumonia

scientific article published on 15 September 2005

Preparation of Purified Gram-positive Bacterial Cell Wall and Detection in Placenta and Fetal Tissues

scientific article

Protection by D-amino acids against growth inhibition and lysis caused by beta-lactam antibiotics

scientific article

Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients

scientific article published on 23 October 2006

Rabbit Model of Bacterial Meningitis

article

Receptor analogs and monoclonal antibodies that inhibit adherence of Bordetella pertussis to human ciliated respiratory epithelial cells

scientific article

Receptor specificity of adherence of Streptococcus pneumoniae to human type-II pneumocytes and vascular endothelial cells in vitro.

scientific article

Recognition of a bacterial adhesion by an integrin: macrophage CR3 (alpha M beta 2, CD11b/CD18) binds filamentous hemagglutinin of Bordetella pertussis

scientific article

Recognition of pneumococcal peptidoglycan: an expanded, pivotal role for LPS binding protein

scientific article

RelA Mutant Enterococcus faecium with Multiantibiotic Tolerance Arising in an Immunocompromised Host

scientific article published on 03 January 2017

Reply

Revising the role of the pneumococcal vex-vncRS locus in vancomycin tolerance

scientific article published on December 2004

Role of autolysins in the activities of imipenem and CGP 31608, a novel penem, against slowly growing bacteria

scientific article

Role of the manganese efflux system mntE for signalling and pathogenesis in Streptococcus pneumoniae

scientific article published on 17 February 2009

Serotype-related differences in inflammatory response to Streptococcus pneumoniae in experimental meningitis

scientific article published in April 1997

Serum immunoglobulin G response to candidate vaccine antigens during experimental human pneumococcal colonization

scientific article

Signal transduction by a death signal peptide: uncovering the mechanism of bacterial killing by penicillin

scientific article published in January 2000

Solution structure of choline binding protein A, the major adhesin of Streptococcus pneumoniae

scientific article

Staphylococcal protein A adsorption of neonatal serum to facilitate early diagnosis of congenital infection

scientific article published on 01 August 1980

Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease

scientific article

Streptococcus pneumoniae

Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor

scientific article

Streptococcus pneumoniae translocates into the myocardium and forms unique microlesions that disrupt cardiac function

scientific article

Streptococcus pneumoniae: Invasion and Inflammation

scholarly article

Streptococcus pneumoniae: The Prototype of Lung Responses in Pneumonia

article

Surprise? Bacteria glycosylate proteins too.

scientific article published on December 1996

Susceptibility to infection and age-related changes in the blood-brain barrier

scientific article published on November 1994

Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

scientific article published on January 1995

The Biology of Pneumococcal Infection ⬇️

scientific article published on September 1, 1997

The Induction of Meningeal Inflammation by Components of the Pneumococcal Cell Wall

scientific article published on 01 May 1985

The Surface of Mammalian Respiratory Cilia Interactions between Cilia and Respiratory Pathogens

The TLR2-MyD88-NOD2-RIPK2 signalling axis regulates a balanced pro-inflammatory and IL-10-mediated anti-inflammatory cytokine response to Gram-positive cell walls

scientific article published on 28 June 2008

The biologic activities of peptidoglycan in experimental Haemophilus influenzae meningitis.

scientific article published in February 1993

The impact of dexamethasone on hearing loss in experimental pneumococcal meningitis

scientific article published in February 1995

The molecular basis of pneumococcal infection: a hypothesis.

scientific article

The murein hydrolases of Escherichia coli: properties, functions and impact on the course of infections in vivo.

scientific article

The mystery of psaA and penicillin tolerance in Streptococcus pneumoniae

scientific article published on 01 June 2000

The p53-target gene puma drives neutrophil-mediated protection against lethal bacterial sepsis

scientific article

The pathophysiology of pneumococcal meningitis.

scientific article

The pneumococcus: epidemiology, microbiology, and pathogenesis

scientific article published on July 2013

The polymeric immunoglobulin receptor translocates pneumococci across human nasopharyngeal epithelial cells

scientific article

The rate of killing of Escherichia coli by beta-lactam antibiotics is strictly proportional to the rate of bacterial growth.

scientific article published in May 1986

The role of complement in inflammation during experimental pneumococcal meningitis

scientific article published on 01 February 1986

The vir Locus Affects the Response of Bordetella pertussis to Antibiotics: Phenotypic Tolerance and Control of Autolysis

scientific article published on 01 August 1990

Tissue-specific contributions of pneumococcal virulence factors to pathogenesis

scientific article published on 21 September 2004

Tolerance to vancomycin in pneumococci: detection with a molecular marker and assessment of clinical impact

scientific article published on 09 September 2004

Toll-Like Receptor 2 Mediates Fatal Immunopathology in Mice During Treatment of Secondary Pneumococcal Pneumonia Following Influenza ⬇️

scientific article published on September 7, 2011

Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

scientific article

Transcytosis and Signalling of Pneumococci at the Blood Brain Barrier

Transglycosylase and endopeptidase participate in the degradation of murein during autolysis of Escherichia coli ⬇️

scientific article

Type I interferon protects against pneumococcal invasive disease by inhibiting bacterial transmigration across the lung

scientific article published in 2013

Unencapsulated Streptococcus pneumoniae from conjunctivitis encode variant traits and belong to a distinct phylogenetic cluster

scientific article

Unveiling Unexpected Immune Activities Induced by Your Pneumococcal Vaccine

scientific article published on January 2015

Vancomycin stress response in a sensitive and a tolerant strain of Streptococcus pneumoniae

scientific article

Vancomycin-tolerant Streptococcus pneumoniae and its clinical significance.

scientific article

Virulence in Mice of Pneumococcal Clonal Types with Known Invasive Disease Potential in Humans

scientific article published in 2005

beta-Arrestin 1 participates in platelet-activating factor receptor-mediated endocytosis of Streptococcus pneumoniae

scientific article

β-Arrestin 1 Participates in Platelet-Activating Factor Receptor-Mediated Endocytosis of Streptococcus pneumoniae.

scientific article published in May 2006

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