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List of works by Mihai Netea

'Trained immunity': consequences for lymphoid malignancies

scientific article

1,25-Dihydroxyvitamin D3 inhibits proliferation but not the suppressive function of regulatory T cells in the absence of antigen-presenting cells

scientific article published on 01 December 2011

1,25-dihydroxyvitamin D3 Modulates Cytokine Production Induced by Candida albicans: Impact of Seasonal Variation of Immune Responses ⬇️

scientific article published on January 1, 2011

A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1.

scientific article

A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans.

scientific article published on November 2016

A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans

scientific article published on 01 July 2019

A Multidisciplinary Approach to Fungal Infections: One-Year Experiences of a Center of Expertise in Mycology

scientific article published on 10 November 2020

A NOD for autophagy

scientific article published on 01 January 2010

A Potential Role for Epigenetically Mediated Trained Immunity in Food Allergy

scientific article published on 17 May 2020

A Salty Taste to Autoimmunity ⬇️

scientific article published on June 27, 2013

A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling

scientific article

A Weakened Immune Response to Synthetic Exo-Peptides Predicts a Potential Biosecurity Risk in the Retrieval of Exo-Microorganisms

scientific article published on 17 July 2020

A comparison of patients with Q fever fatigue syndrome and patients with chronic fatigue syndrome with a focus on inflammatory markers and possible fatigue perpetuating cognitions and behaviour

scientific article published on 17 July 2015

A comprehensive analysis of pattern recognition receptors in normal and inflamed human epidermis: upregulation of dectin-1 in psoriasis.

scientific article published on 15 July 2010

A genome-wide functional genomics approach uncovers genetic determinants of immune phenotypes in type 1 diabetes

scientific article published in 2022

A guiding map for inflammation

scientific article published on July 2017

A higher BMI is not associated with a different immune response and disease course in critically ill COVID-19 patients

scientific article published on 25 January 2021

A joint effort: The interplay between the innate and the adaptive immune system in Lyme arthritis

scientific article published on 13 January 2020

A missense mutation underlies defective SOCS4 function in a family with autoimmunity.

scientific article published on 10 March 2015

A multifunctional mannosyltransferase family in Candida albicans determines cell wall mannan structure and host-fungus interactions.

scientific article

A polysaccharide virulence factor from Aspergillus fumigatus elicits anti-inflammatory effects through induction of Interleukin-1 receptor antagonist

scientific article (publication date: March 2014)

A possible link between recurrent upper respiratory tract infections and lower cytokine production in patients with Q fever fatigue syndrome

scientific article published on 09 May 2019

A possible role for mitochondrial-derived peptides humanin and MOTS-c in patients with Q fever fatigue syndrome and chronic fatigue syndrome

article

A promoter polymorphism in human interleukin-32 modulates its expression and influences the risk and the outcome of epithelial cell-derived thyroid carcinoma

scientific article published on 13 March 2013

A role for TLR1, TLR2 and NOD2 in cytokine induction by Bacteroides fragilis.

scientific article

A role for TLR10 in obesity and adipose tissue morphology

scientific article published on 23 April 2018

A small jab - a big effect: nonspecific immunomodulation by vaccines

scientific article

A systems approach to inflammation identifies therapeutic targets in SARS-CoV-2 infection

scientific article published on 25 May 2020

A targeted association study of immunity genes and networks suggests novel associations with placental malaria infection.

scientific article

ADAMTS13 deficiency with elevated levels of ultra-large and active von Willebrand factor in P. falciparum and P. vivax malaria.

scientific article

AIDS-related mycoses: the way forward

scientific article

ATG16L1 polymorphisms are associated with NOD2-induced hyperinflammation

scientific article published on 01 September 2011

Acromegaly, inflammation and cardiovascular disease: a review

scientific article published on 26 May 2020

Activate: Randomized Clinical Trial of BCG Vaccination against Infection in the Elderly

scientific article published on 01 September 2020

Activation of innate host defense mechanisms by Borrelia

scientific article published on March 2010

Activation of proteinase 3 contributes to Non-alcoholic Fatty Liver Disease (NAFLD) and insulin resistance

scientific article published on 16 May 2016

Adaptation and memory in innate immunity

scientific article published in August 2016

Adaptive Characteristics of Innate Immune Responses in Macrophages

scientific article

Adaptive Characteristics of Innate Immune Responses in Macrophages

article

Adjuvant interferon-gamma immunotherapy in a patient with progressive cerebral Nocardia abscesses

scientific article published on 22 March 2017

Advances in understanding molecular regulation of innate immune memory

scientific article published on 25 January 2020

Adverse events and association with age, sex and immunological parameters of Q fever vaccination in patients at risk for chronic Q fever in the Netherlands 2011.

scientific article published on November 2014

Akkermansia muciniphila Exerts Lipid-Lowering and Immunomodulatory Effects without Affecting Neointima Formation in Hyperlipidemic APOE*3-Leiden.CETP Mice

scientific article published on 06 August 2019

Aldosterone induces trained immunity: the role of fatty acid synthesis

scientific article published on 01 February 2020

Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1β and by the induction of endogenous IL-1Ra

scientific article published on 14 July 2015

Altered interferon-γ response in patients with Q-fever fatigue syndrome

scientific article

Alternatively spliced isoforms of IL-32 differentially influence cell death pathways in cancer cell lines

scientific article published on 17 December 2015

An anti-inflammatory property of Candida albicans β-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism

scientific article

An elevated pro-inflammatory cytokine response is linked to development of amphotericin B-induced nephrotoxicity

scientific article

An enigma: why vitamin A supplementation does not always reduce mortality even though vitamin A deficiency is associated with increased mortality

scientific article

An exaggerated monocyte-derived cytokine response to Candida hyphae in patients with recurrent vulvovaginal candidiasis

scientific article published on 23 July 2020

An integrated model of the recognition of Candida albicans by the innate immune system.

scientific article

An integrative genomics approach identifies KDM4 as a modulator of trained immunity

scientific article published in 2021

An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility

scientific article

Anakinra treatment in critically ill COVID-19 patients: a prospective cohort study

scientific article published on 10 December 2020

Ancient DNA from South-East Europe Reveals Different Events during Early and Middle Neolithic Influencing the European Genetic Heritage.

scientific article published on 8 June 2015

Anti-Aspergillus human host defence relies on type 1 T helper (Th1), rather than type 17 T helper (Th17), cellular immunity.

scientific article published on 2 December 2009

Anti-TNF therapy and plasma HDL cholesterol concentration

scientific article published in October 2005

Anti-mycobacterial activity correlates with altered DNA methylation pattern in immune cells from BCG-vaccinated subjects

scientific article published on 26 September 2017

Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity

scientific article published on 04 March 2019

Antifungal immune responses: emerging host-pathogen interactions and translational implications.

scientific article

Antifungal innate immunity: recognition and inflammatory networks

scientific article published on 20 December 2014

Antigen-Independent Restriction of Pneumococcal Density by Mucosal Adjuvant Cholera Toxin Subunit B.

scientific article

Apolipoprotein-E-deficient mice exhibit an increased susceptibility to disseminated candidiasis.

scientific article

Are histones real pathogenic agents in sepsis?

scientific article published on 27 December 2017

Arterial Wall Inflammation and Increased Hematopoietic Activity in Patients With Primary Aldosteronism

scientific article published on 01 May 2020

Aspergillus Cell Wall Melanin Blocks LC3-Associated Phagocytosis to Promote Pathogenicity

scientific article

Aspergillus fumigatus cell wall components differentially modulate host TLR2 and TLR4 responses

scientific article published on 04 November 2010

Aspergillus fumigatus conidial melanin modulates host cytokine response.

scientific article

Aspergillus fumigatus evades immune recognition during germination through loss of toll-like receptor-4-mediated signal transduction

scientific article published on 01 July 2003

Aspergillus fumigatus morphology and dynamic host interactions

scientific article published on 18 September 2017

Aspergillus fumigatus-induced IL-22 is not restricted to a specific Th cell subset and is dependent on complement receptor 3.

scientific article

Assessment of inflammasome activation in primary human immune cells.

scientific article published in January 2013

Association between genotypes of rs34436714 of NLRP12 and serum tumor necrosis factor-alpha in inflammatory bowel disease: A case-control study

scientific article published on 01 June 2019

Association of Mal/TIRAP S180L variant polymorphism with decreased infection risk in patients with advanced HIV-1 infection

article

Association of hemoglobin A1C with circulating metabolites in Dutch with European, African Surinamese and Ghanaian background

scientific article published on 30 April 2019

Association of toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms with increased infection risk in patients with advanced HIV-1 infection

scientific article published in July 2010

Atherogenic effects of chlamydia pneumoniae: refuting the innocent bystander hypothesis ⬇️

scientific article published on September 1, 2003

Author Correction: A guiding map for inflammation

scientific article published on 07 December 2020

Author Correction: Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations

scientific article published in 2021

Author Correction: Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome

scholarly article published in Nature Genetics

Author Correction: Trained immunity, tolerance, priming and differentiation: distinct immunological processes

scientific article published in 2021

Author Correction: Transmission of trained immunity and heterologous resistance to infections across generations

scientific article published in 2023

Autophagy controls BCG-induced trained immunity and the response to intravesical BCG therapy for bladder cancer

scientific article

Autophagy in adipose tissue and the beta cell: implications for obesity and diabetes

scientific article published on 05 May 2014

Autophagy modulates Borrelia burgdorferi-induced production of interleukin-1β (IL-1β)

scientific article published on 5 February 2013

Autophagy modulates the Mycobacterium tuberculosis-induced cytokine response.

scientific article

Autophagy suppresses host adaptive immune responses toward Borrelia burgdorferi

scientific article published on 21 April 2016

B. burgdorferisensu lato-induced inhibition of antigen presentation is mediated by RIP1 signaling resulting in impaired functional T cell responses towards Candida albicans

scientific article published on 23 November 2020

BCG Vaccination Enhances the Immunogenicity of Subsequent Influenza Vaccination in Healthy Volunteers: A Randomized, Placebo-Controlled Pilot Study.

scientific article

BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils

scientific article published on 01 November 2020

BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity

scientific article published in January 2018

BCG Vaccination in Humans Elicits Trained Immunity via the Hematopoietic Progenitor Compartment

scientific article published on 09 June 2020

BCG vaccination in healthcare providers and the protection against COVID-19

scientific article published on 11 December 2020

BCG vaccination in humans inhibits systemic inflammation in a sex-dependent manner

scientific article published on 21 July 2020

BCG vaccination is associated with reduced malaria prevalence in children under the age of 5 years in sub-Saharan Africa

scientific article published on 14 November 2019

BCG-Induced Trained Immunity in Healthy Individuals: The Effect of Plasma Muramyl Dipeptide Concentrations

scientific article published on 15 June 2020

BCG-induced protection: effects on innate immune memory

scientific article

BCG-induced trained immunity enhances acellular pertussis vaccination responses in an explorative randomized clinical trial

scientific article published in 2022

BCG-induced trained immunity in NK cells: Role for non-specific protection to infection

scientific article published on 25 October 2014

BCG-induced trained immunity: can it offer protection against COVID-19?

scientific article published on 11 May 2020

BMT decreases HFD-induced weight gain associated with decreased preadipocyte number and insulin secretion.

scientific article published on 26 April 2017

Bacille Calmette-Guérin (BCG) vaccination at birth and antibody responses to childhood vaccines. A randomised clinical trial

scientific article

Bacille Calmette-Guérin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes ⬇️

scientific article published on September 17, 2012

Bacillus Calmette-Guérin-Induced Trained Immunity Is Not Protective for Experimental Influenza A/Anhui/1/2013 (H7N9) Infection in Mice.

scientific article

Bacterial translocation in an experimental model of multiple organ dysfunctions

scientific article published on 22 February 2013

Bartonella quintana lipopolysaccharide (LPS): structure and characteristics of a potent TLR4 antagonist for in-vitro and in-vivo applications

scientific article

Bartonella quintana lipopolysaccharide is a natural antagonist of Toll-like receptor 4

scientific article

Basic Genetics and Immunology of Candida Infections

scientific article published on March 2016

Be aware, innate immune cells remember

Bimodal Influence of Vitamin D in Host Response to Systemic Candida Infection-Vitamin D Dose Matters

scientific article published on 22 January 2015

Biomarkers of inflammation and the etiology of sepsis

scientific article published on 01 February 2020

Black yeasts and their filamentous relatives: principles of pathogenesis and host defense

scientific article

Blocking IL-1 to prevent respiratory failure in COVID-19

scientific article published on 18 July 2020

Blueprints of signaling interactions between pattern recognition receptors: implications for the design of vaccine adjuvants.

scientific article published on 23 January 2013

Bone marrow transplantation induces changes in the gut microbiota that chronically increase the cytokine response pattern of splenocytes

scientific article published in 2022

Bone marrow-specific caspase-1/11 deficiency inhibits atherosclerosis development in Ldlr(-/-) mice

scientific article published on 20 April 2015

Borrelia burgdorferi hijacks cellular metabolism of immune cells: Consequences for host defense

scientific article published on 03 February 2020

Borrelia species induce inflammasome activation and IL-17 production through a caspase-1-dependent mechanism

scientific article published on 09 December 2010

Borrelia-induced cytokine production is mediated by spleen tyrosine kinase (Syk) but is Dectin-1 and Dectin-2 independent.

scientific article published on 18 August 2015

Both TLR2 and TLR4 are involved in the recognition of Candida albicans. Reply to "TLR2, but not TLR4, triggers cytokine production by murine cells in response to Candida albicans yeasts and hyphae" by Gil and Gozalbo, Microbes and Infection 8 (2006)

scientific article published on 28 August 2006

Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis

scientific article

Bromodomain inhibitor I-BET151 suppresses immune responses during fungal-immune interaction

scientific article published on 21 June 2019

Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans

scientific article published in April 2009

CBLB ubiquitin ligase: a major regulator of antifungal immunity

scientific article published on August 2016

CD40/CD40 ligand interactions in the host defense against disseminated Candida albicans infection: the role of macrophage-derived nitric oxide

scientific article published on 01 May 2002

CLEC4F is an inducible C-type lectin in F4/80-positive cells and is involved in alpha-galactosylceramide presentation in liver

scientific journal article

COVID-19-Associated Candidiasis (CAC): An Underestimated Complication in the Absence of Immunological Predispositions?

scientific article published on 08 October 2020

CRELD1 modulates homeostasis of the immune system in mice and humans

scientific article published on 09 November 2020

CX3CR1 is dispensable for control of mucosal Candida albicans infections in mice and humans

scientific article

CX3CR1-dependent renal macrophage survival promotes Candida control and host survival

scientific article

CXCL9, a promising biomarker in the diagnosis of chronic Q fever

scientific article published on 9 August 2017

CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival.

scientific article published on January 2016

Candida albicans and Candida parapsilosis induce different T-cell responses in human peripheral blood mononuclear cells

scientific article published on 09 May 2013

Candida albicans dampens host defense by downregulating IL-17 production.

scientific article published on 12 July 2010

Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes.

scientific article published on August 2012

Candida albicans morphogenesis and host defence: discriminating invasion from colonization. ⬇️

scientific article published on 12 December 2011

Candida albicans primes TLR cytokine responses through a Dectin-1/Raf-1-mediated pathway

scientific article published on 8 March 2013

Candida albicans releases soluble factors that potentiate cytokine production by human cells through a protease-activated receptor 1- and 2-independent pathway

scientific article published on 26 October 2009

Candida and Host Determinants of Susceptibility to Invasive Candidiasis ⬇️

scientific article published on January 3, 2013

Case 39-2014: A girl with Crohn's disease and pulmonary nodules

scientific article published in March 2015

Caspase-1 deficiency in mice reduces intestinal triglyceride absorption and hepatic triglyceride secretion

scientific article published on 17 November 2012

Caspase-12 and the inflammatory response to Yersinia pestis

scientific article

Caspase-3-independent apoptotic pathways contribute to interleukin-32γ-mediated control of Mycobacterium tuberculosis infection in THP-1 cells

scientific article

Catecholamines Induce Trained Immunity In Monocytes In Vitro and In Vivo

scientific article published on 03 April 2020

Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases

scientific article published on 18 February 2019

Cell Wall Changes in Amphotericin B-Resistant Strains from Candida tropicalis and Relationship with the Immune Responses Elicited by the Host

scientific article published on February 2016

Cellular metabolism of myeloid cells in sepsis

scientific article

Cellular metabolism of tumor-associated macrophages - functional impact and consequences.

scientific article

Cerebral tryptophan metabolism and outcome of tuberculous meningitis: an observational cohort study.

scientific article published on 23 January 2018

Cerebrospinal fluid IL-1β is elevated in tuberculous meningitis patients but not associated with mortality

scientific article published on 11 November 2020

Changing oral vaccine to inactivated polio vaccine might increase mortality

scientific article published on March 2016

Characterization of the Acute Inflammatory Response in Measles Infection

scientific article published on 10 December 2013

Chlamydia pneumoniae stimulates IFN-gamma synthesis through MyD88-dependent, TLR2- and TLR4-independent induction of IL-18 release

scientific article published on July 2004

Chocolate consumption modulates cytokine production in healthy individuals

scientific article

Circadian rhythm influences induction of trained immunity by BCG vaccination

scientific article published on 21 July 2020

Circulating leptin and adiponectin concentrations during tumor necrosis factor blockade in patients with active rheumatoid arthritis

scientific article published on 27 February 2009

Circulating lipoproteins are a crucial component of host defense against invasive Salmonella typhimurium infection

scientific article

Clinical Parameters, Routine Inflammatory Markers, and LTA4H Genotype as Predictors of Mortality Among 608 Patients With Tuberculous Meningitis in Indonesia

scientific article

Combination of biomarkers for the discrimination between bacterial and viral lower respiratory tract infections ⬇️

scientific article published on August 13, 2012

Combined B- and T-cell deficiency does not protect against obesity-induced glucose intolerance and inflammation ⬇️

scientific article published on March 9, 2013

Comment on "Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome"

scientific article published in Science

Common gene variants within 3'-untranslated regions as modulators of multiple myeloma risk and survival

scientific article published on 05 November 2020

Comparative analysis of neutrophil and monocyte epigenomes

Compartmentalized Cytokine Responses in Hidradenitis Suppurativa

scientific article published on 19 June 2015

Complement activation in the disease course of COVID-19 and its effects on clinical outcomes

scientific article published on 10 October 2020

Complement plays a central role in Candida albicans-induced cytokine production by human PBMCs

scientific article published on 01 April 2012

Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure

scientific article published on 17 April 2020

Considering BCG vaccination to reduce the impact of COVID-19

scientific article published on 30 April 2020

Contribution of Genetic and Clinical Risk Factors to Development of Candidemia in Patients Receiving Home Parenteral Nutrition

scientific article published on 10 May 2019

Controlled Human Malaria Infection Induces Long-Term Functional Changes in Monocytes

scientific article published on 26 November 2020

Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-like receptors

scientific article published on 03 February 2014

Correction for Bekkering et al., "In Vitro Experimental Model of Trained Innate Immunity in Human Primary Monocytes".

scientific article published on 5 May 2017

Correction to: Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein

scientific article published on 11 June 2020

Correction to: Two Randomized Controlled Trials of Bacillus Calmette-Guérin Vaccination to reduce absenteeism among health care workers and hospital admission by elderly persons during the COVID-19 pandemic: A structured summary of the study protoco

scientific article published on 22 June 2020

Correction: Differential Adaptation of Candida albicans In Vivo Modulates Immune Recognition by Dectin-1.

scientific article published on 30 October 2013

Corrigendum: Bacillus Calmette-Guérin-Induced Trained Immunity Is Not Protective for Experimental Influenza A/Anhui/1/2013 (H7N9) Infection in Mice

scholarly article published in Frontiers in Immunology

Corticosteroids block autophagy protein recruitment in Aspergillus fumigatus phagosomes via targeting dectin-1/Syk kinase signaling

scientific article published on July 2013

Crohn's disease patients homozygous for the 3020insC NOD2 mutation have a defective NOD2/TLR4 cross-tolerance to intestinal stimuli

scientific article published on 20 November 2007

Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2

scientific article published on 15 March 2011

Cryptococcus gattii induces a cytokine pattern that is distinct from other cryptococcal species

scientific article

Current gaps in sepsis immunology: new opportunities for translational research

scientific article published on 17 October 2019

Cutting Edge: Plasmodium falciparum Induces Trained Innate Immunity.

scientific article published on 12 January 2018

Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study

scientific article published on 5 December 2011

Cytokine inhibition in chronic fatigue syndrome patients: study protocol for a randomized controlled trial

scientific article

Cytokine production assays reveal discriminatory immune defects in adults with recurrent infections and noninfectious inflammation

scientific article

Cytokine production from stimulated whole blood cultures in rheumatoid arthritis patients treated with various TNF blocking agents

scientific article published in June 2009

Cytokine production of stimulated whole blood cultures in rheumatoid arthritis patients receiving short-term infliximab therapy

scientific article published on April 2005

Cytokine profiles in patients with Q fever fatigue syndrome

scientific article published on 23 January 2019

Cytokine release in healthy donors and patients with chronic granulomatous disease upon stimulation with Aspergillus fumigatus

scientific article published on 01 January 2003

Cytokine responses and regulation of interferon-gamma release by human mononuclear cells to Aspergillus fumigatus and other filamentous fungi

scientific article published on 01 November 2005

DNA Synthesis Is Activated in Mosquitoes and Human Monocytes During the Induction of Innate Immune Memory

scientific article published on 30 November 2018

DNA hyper-methylation during Tuberculosis dampens host immune responsiveness

scientific article published on 03 March 2020

DNA methylation in childhood asthma: an epigenome-wide meta-analysis

scientific article published on 26 February 2018

Deconvolution of bulk blood eQTL effects into immune cell subpopulations

scientific article published on 12 June 2020

Decreased plasma leptin concentrations in tuberculosis patients are associated with wasting and inflammation

scientific article

Dectin-1 plays a redundant role in the immunomodulatory activities of β-glucan-rich ligands in vivo.

scientific article published on 19 March 2013

Dectin-1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages

scientific article published on 28 June 2008

Dectin-2 is a primary receptor for NLRP3 inflammasome activation in dendritic cell response to Histoplasma capsulatum.

scientific article published on 3 July 2017

Defective acute inflammation in Crohn's disease

scientific article published on 01 August 2006

Defective cytokine production early after multiple traumas: Modulation in severe sepsis

scientific article published on 13 June 2015

Defects of pattern recognition: primary immunodeficiencies of the innate immune system

scientific article published on 16 April 2011

Deficiency of interleukin-1 receptor-associated kinase 4 presenting as fatal Pseudomonas aeruginosa bacteremia in two siblings

scientific article published on March 2015

Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance

scientific article published on 28 May 2006

Deficient Candida-specific T-helper 17 response during sepsis

scientific article published on 14 September 2012

Deficient interleukin-17 production in response to Mycobacterium abscessus in cystic fibrosis

scientific article

Defining trained immunity and its role in health and disease

scientific article published on 04 March 2020

Delayed clearance of intraabdominal abscesses caused by Candida albicans in tumor necrosis factor-alpha- and lymphotoxin-alpha-deficient mice

scientific article published on 22 November 2002

Deletion of haematopoietic Dectin-2 or CARD9 does not protect from atherosclerosis development under hyperglycaemic conditions

scientific article published on 23 December 2019

Deletion of hematopoietic Dectin-2 or CARD9 does not protect against atherosclerotic plaque formation in hyperlipidemic mice

scientific article published on 13 March 2019

Dendritic cell interaction with Candida albicans critically depends on N-linked mannan.

scientific article published on 15 May 2008

Derived immune and ancestral pigmentation alleles in a 7,000-year-old Mesolithic European

scientific article

Design of efficacy trials of cytokines in combination with antifungal drugs.

scientific article published on October 2004

Development of Endotoxin Tolerance Does Not Influence the Response to a Challenge with the Mucosal Live-Attenuated Influenza Vaccine in Humans In Vivo

scientific article published on 11 December 2017

Diabetes Mellitus and Increased Tuberculosis Susceptibility: The Role of Short-Chain Fatty Acids

scientific article

Diabetes propels the risk for cardiovascular disease: sweet monocytes becoming aggressive?

scientific article

Differential Effects of Environmental and Genetic Factors on T and B Cell Immune Traits

scientific article

Differential IL-17 Production and Mannan Recognition Contribute to Fungal Pathogenicity and Commensalism

article

Differential Toll-like receptor recognition and induction of cytokine profile by Bifidobacterium breve and Lactobacillus strains of probiotics.

scientific article

Differential adaptation of Candida albicans in vivo modulates immune recognition by dectin-1

scientific article

Differential cytokine production and Toll-like receptor signaling pathways by Candida albicans blastoconidia and hyphae

scientific article

Differential effects of BCG vaccine on immune responses induced by vi polysaccharide typhoid fever vaccination: an explorative randomized trial

scientific article published on 17 February 2020

Differential effects of IL-17 pathway in disseminated candidiasis and zymosan-induced multiple organ failure

scientific article published on 01 October 2010

Differential effects of platelets and platelet inhibition by ticagrelor on TLR2- and TLR4-mediated inflammatory responses

scientific article published on 26 February 2015

Differential ex vivo and in vivo endotoxin tolerance kinetics following human endotoxemia* ⬇️

scientific article published on August 1, 2011

Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis

scholarly article

Differential in vitro cytokine induction by the species of Cryptococcus gattii complex

scientific article published on 8 January 2018

Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages

scientific article published on 22 December 2008

Differential role of IL-18 and IL-12 in the host defense against disseminated Candida albicans infection

scientific article published on 01 December 2003

Differential role of NK cells against Candida albicans infection in immunocompetent or immunocompromised mice

scientific article published on 27 May 2014

Differential susceptibility to lethal endotoxaemia in mice deficient in IL-1α, IL-1β or IL-1 receptor type I.

scientific article published on 11 October 2010

Digitalis-like Compounds Facilitate Non-Medullary Thyroid Cancer Redifferentiation through Intracellular Ca2+, FOS, and Autophagy-Dependent Pathways

scientific article published on 11 November 2016

Distinct inactivated bacterial-based immune modulators vary in their therapeutic efficacies for treating disease based on the organ site of pathology

scientific article published on 03 April 2020

Divergent effects of tumor necrosis factor-alpha and lymphotoxin-alpha on lethal endotoxemia and infection with live Salmonella typhimurium in mice.

scientific article

Diversity and Ecology of Caudoviricetes Phages with Genome Terminal Repeats in Fecal Metagenomes from Four Dutch Cohorts

scientific article published in 2022

Diversity: A Hallmark of Monocyte Society ⬇️

scientific article published on September 24, 2010

Does the shape of lipid A determine the interaction of LPS with Toll-like receptors?

scientific article

Drosomycin-like defensin, a human homologue of Drosophila melanogaster drosomycin with antifungal activity

scientific article

Early Clearance of Mycobacterium tuberculosis Is Associated With Increased Innate Immune Responses

scientific article published on 1 March 2020

Early Clearance of Mycobacterium tuberculosis: The INFECT Case Contact Cohort Study in Indonesia

scientific article published on 1 March 2020

Early Proinflammatory Cytokines and C‐Reactive Protein Trends as Predictors of Outcome in Invasive Aspergillosis

scientific article published on 01 November 2010

Early clearance of Mycobacterium tuberculosis: a new frontier in prevention

scientific article published in April 2014

Early cytokine and antibody responses against Coxiella burnetii in aerosol infection of BALB/c mice

scientific article published on 30 December 2014

Early serum galactomannan trend as a predictor of outcome of invasive aspergillosis ⬇️

scientific article

Early stop polymorphism in human DECTIN-1 is associated with increased candida colonization in hematopoietic stem cell transplant recipients.

scientific article published in September 2009

Early versus late BCG vaccination in HIV-1-exposed infants in Uganda: study protocol for a randomized controlled trial

scientific article published on 31 March 2017

Ebola Virus Disease has Features of Hemophagocytic Lymphohistiocytosis Syndrome

scientific article

Effect of PTEN inactivating germline mutations on innate immune cell function and thyroid cancer-induced macrophages in patients with PTEN hamartoma tumor syndrome

scientific article published on 22 January 2019

Effect of Vegan Fecal Microbiota Transplantation on Carnitine- and Choline-Derived Trimethylamine-N-Oxide Production and Vascular Inflammation in Patients With Metabolic Syndrome.

scientific article

Effect of clarithromycin in inflammatory markers of patients with ventilator-associated pneumonia and sepsis caused by Gram-negative bacteria: results from a randomized clinical study

scientific article published on 7 May 2012

Effects of Bacillus Calmette-Guérin (BCG) vaccination at birth on T and B lymphocyte subsets: Results from a clinical randomized trial

scientific article published on 29 September 2017

Effects of hydrophobicity on the antifungal activity of alpha-helical antimicrobial peptides

scientific article published on December 2008

Effects of oral butyrate supplementation on inflammatory potential of circulating peripheral blood mononuclear cells in healthy and obese males

scientific article published in Scientific Reports

Endogenous Interleukin (IL)–1α and IL‐1β Are Crucial for Host Defense against Disseminated Candidiasis

scientific article published on 04 April 2006

Endoplasmic reticulum alpha-glycosidases of Candida albicans are required for N glycosylation, cell wall integrity, and normal host-fungus interaction

scientific article

Engagement of NOD2 has a dual effect on proIL-1beta mRNA transcription and secretion of bioactive IL-1beta

scientific article published in January 2008

Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis

scientific article

Enhanced interleukin-1β production of PBMCs from patients with gout after stimulation with Toll-like receptor-2 ligands and urate crystals

scientific article published on 4 July 2012

Enhanced lipid biosynthesis in human tumor-induced macrophages contributes to their protumoral characteristics

scientific article published on 01 September 2020

Environmental Signals Influencing Myeloid Cell Metabolism and Function in Diabetes

scientific article published on 19 May 2018

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity.

scientific article published on September 2014

Epigenetics and trained immunity.

scientific article published on 5 October 2017

Epithelial Sensing of Fungal Invasion ⬇️

scientific article published on September 16, 2010

Epitope Shaving Promotes Fungal Immune Evasion

scientific article published on 07 July 2020

Erratum: Corrigendum: IL-37 protects against obesity-induced inflammation and insulin resistance

scientific article published on 12 January 2015

Erratum: Corrigendum: Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi

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Erratum: IL-1 family nomenclature

scholarly article by Charles A. Dinarello et al published March 2011 in Nature Immunology

Evolution of cytokine production capacity in ancient and modern European populations

scientific article published in 2021

Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection

scientific article

Ex-vivo inhibited cytokine profiling explains inferior treatment response to golimumab after adalimumab failure in rheumatoid arthritis

scientific article published on 18 October 2017

Exciting Developments in the Immunology of Fungal Infections ⬇️

scientific article published on May 17, 2012

Exome sequencing in routine diagnostics: a generic test for 254 patients with primary immunodeficiencies.

scientific article published on 17 June 2019

Exposure to Candida albicans polarizes a T-cell driven arthritis model towards Th17 responses, resulting in a more destructive arthritis

scientific article (publication date: 2012)

Expression of TLR4 protein is reduced in chronic renal failure: evidence from an experimental model of nephron reduction

scientific article published in January 2015

FAVORABLE ANAKINRA RESPONSES IN SEVERE COVID-19 PATIENTS WITH SECONDARY HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS

scientific article published on 14 May 2020

Female-specific Association Between Variants on Chromosome 9 and Self-reported Diagnosis of Irritable Bowel Syndrome

scientific article published on 4 April 2018

Firing Up Glycolysis: BCG Vaccination Effects on Type 1 Diabetes Mellitus

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From the Th1/Th2 paradigm towards a Toll-like receptor/T-helper bias

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Frontline Science: Endotoxin-induced immunotolerance is associated with loss of monocyte metabolic plasticity and reduction of oxidative burst

scientific article published on 06 June 2019

Functional Annotation of Genetic Loci Associated With Sepsis Prioritizes Immune and Endothelial Cell Pathways

scientific article published on 14 August 2019

Functional and Genomic Architecture of Borrelia burgdorferi-Induced Cytokine Responses in Humans.

scientific article published on November 2016

Functional and genetic evidence that the Mal/TIRAP allele variant 180L has been selected by providing protection against septic shock

scholarly article

Functional consequences of DECTIN-1 early stop codon polymorphism Y238X in rheumatoid arthritis

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Functional consequences of the Asp299Gly Toll-like receptor-4 polymorphism

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Functional consequences of toll-like receptor 4 polymorphisms

scientific article published on May 2008

Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans

scientific article published on January 2013

Fungal Chitin Induces Trained Immunity in Human Monocytes during Cross-talk of the Host with Saccharomyces cerevisiae.

scientific article published on 17 February 2016

Fungal chitin dampens inflammation through IL-10 induction mediated by NOD2 and TLR9 activation.

scientific article

Fungal infections: the next challenge ⬇️

scientific article published on July 31, 2012

Fungal strategies for overcoming host innate immune response

scientific article published on 24 July 2008

Fusarium ramigenum, a novel human opportunist in a patient with common variable immunodeficiency and cellular immune defects: case report

scientific article published on 15 February 2016

Gain-of-function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC).

scientific article

Gamma-irradiated bacille Calmette-Guérin vaccination does not modulate the innate immune response during experimental human endotoxemia in adult males

scientific article

Gender differences in the innate immune response and vascular reactivity following the administration of endotoxin to human volunteers.

scientific article published on June 2007

Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasis

scientific article

Genetic Basis for Recurrent Vulvo-Vaginal Candidiasis ⬇️

scientific article published on April 1, 2013

Genetic Variation in Pattern Recognition Receptors and Adaptor Proteins Associated With Development of Chronic Q Fever

scientific article published on 26 February 2015

Genetic Variation in TLR10, an Inhibitory Toll-Like Receptor, Influences Susceptibility to Complicated Skin and Skin Structure Infections

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Genetic adaptation of the antibacterial human innate immunity network

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Genetic and Microbial Associations to Plasma and Fecal Bile Acids in Obesity Relate to Plasma Lipids and Liver Fat Content

scientific article published on 01 October 2020

Genetic and pharmacological inhibition of vanin-1 activity in animal models of type 2 diabetes

scientific article published on 2 March 2016

Genetic association analysis of the functional c.714T>G polymorphism and mucosal expression of dectin-1 in inflammatory bowel disease

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Genetic diversity of lactase persistence in East African populations.

scientific article published on 4 January 2016

Genetic susceptibility to Candida infections

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Genetic variant in IL-32 is associated with the ex vivo cytokine production of anti-TNF treated PBMCs from rheumatoid arthritis patients

scientific article published in Scientific Reports

Genetic variation in TLR10 is not associated with chronic Q fever, despite the inhibitory effect of TLR10 on Coxiella burnetii-induced cytokines in vitro.

scientific article published on 10 September 2015

Genetic variation in Toll-like receptors and disease susceptibility

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Genetic variation in pattern recognition receptors: functional consequences and susceptibility to infectious disease.

scientific article published on June 2015

Genetic variation in the dectin-1/CARD9 recognition pathway and susceptibility to candidemia

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Genetic variation of TLR2 and TLR4 among the Saudi Arabian population: insight into the evolutionary dynamics of the Arabian Peninsula

scientific article published on 4 January 2013

Genetic variation of innate immune genes in HIV-infected african patients with or without oropharyngeal candidiasis.

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Genetic variation in Interleukin-32 influence the immune response against New World Leishmania species and susceptibility to American Tegumentary Leishmaniasis

scientific article published on 05 February 2020

Genome-Wide Association Study Identifies Novel Colony Stimulating Factor 1 Locus Conferring Susceptibility to Cryptococcosis in Human Immunodeficiency Virus-Infected South Africans

scientific article published on 16 October 2020

Genomewide association study of leprosy

scientific article published in April 2010

Genomic analysis of Andamanese provides insights into ancient human migration into Asia and adaptation

scientific article published on 25 July 2016

Genomics of Mesolithic Scandinavia reveal colonization routes and high-latitude adaptation

Getting to the marrow of trained immunity

scientific article published on 01 September 2018

Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity

scientific article published on 16 November 2016

Growth of Candida albicans cells on the physiologically relevant carbon source lactate affects their recognition and phagocytosis by immune cells.

scientific article published on 31 October 2012

Growth on Carbohydrates from Carbonaceous Meteorites Alters the Immunogenicity of Environment-Derived Bacterial Pathogens

scientific article published on 08 May 2020

Guidelines for the use and interpretation of assays for monitoring autophagy

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

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Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk

scientific article published on 11 April 2019

Gut microbial co-abundance networks show specificity in inflammatory bowel disease and obesity

scientific article published on 11 August 2020

Gut microbiome in ADHD and its relation to neural reward anticipation

scientific article published on September 2017

Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations

scientific article published in 2021

H4:IC31 Vaccine or BCG Revaccination for Tuberculosis

scientific article published on 01 November 2018

Hard to Remember: Long-Term Functional Defects in Myeloid Cells and Wound Repair After Sepsis

scientific article published on 23 October 2019

Harnessing the beneficial heterologous effects of vaccination

scientific article published on 09 May 2016

Heroin use is associated with suppressed pro-inflammatory cytokine response after LPS exposure in HIV-infected individuals

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Heterologous immunological effects of early BCG vaccination in low-birth-weight infants in Guinea-Bissau: a randomized-controlled trial

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Heterologous vaccine effects

scientific article published on 13 June 2016

Hidden killers: human fungal infections

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High variability of TLR4 gene in different ethnic groups in Iran

scientific article published on 12 October 2011

High-Mobility Group Nucleosome-Binding Protein 1 as Endogenous Ligand Induces Innate Immune Tolerance in a TLR4-Sirtuin-1 Dependent Manner in Human Blood Peripheral Mononuclear Cells.

scientific article published on 14 March 2018

High-dose vitamin D3 supplementation is a requisite for modulation of skin-homing markers on regulatory T cells in HIV-infected patients

scientific article published on 29 August 2012

Host Genetic Signatures of Susceptibility to Fungal Disease

scientific article published on 01 January 2019

Host Genomics and Bacterial Infections

Host Genomics and Bacterial Infections

Host and Environmental Factors Influencing Individual Human Cytokine Responses

scientific article published on November 2016

Host defence against disseminated Candida albicans infection and implications for antifungal immunotherapy

scientific article published on September 2006

Host-microbe interactions in stem cell transplantation: recognizing Candida in infection and inflammation

scientific article published on 01 May 2010

Host-microbe interactions: innate pattern recognition of fungal pathogens

scientific article published on 17 July 2008

How the COVID-19 pandemic highlights the necessity of animal research

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How the COVID-19 pandemic highlights the necessity of animal research

scientific article published on 01 November 2020

Human TLR10 is an anti-inflammatory pattern-recognition receptor

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Human dectin-1 deficiency and mucocutaneous fungal infections

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Human dendritic cells are less potent at killing Candida albicans than both monocytes and macrophages

scientific article published on 01 September 2004

Human genetic susceptibility to Candida infections.

scientific article published on 04 June 2012

Human lipoproteins have divergent neutralizing effects on E. coli LPS, N. meningitidis LPS, and complete Gram-negative bacteria

scientific article published in February 2004

Hydroxychloroquine Inhibits the Trained Innate Immune Response to Interferons

scientific article published on 10 November 2020

Hyperamylinemia Increases IL-1β Synthesis in the Heart via Peroxidative Sarcolemmal Injury

scientific article published on 22 June 2016

Hyperferritinaemia in dengue virus infected patients is associated with immune activation and coagulation disturbances

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Hyperglycemia Activates Caspase-1 and TXNIP-Mediated IL-1β Transcription in Human Adipose Tissue ⬇️

scientific article published on February 1, 2011

Hypothesis: stimulation of trained immunity as adjunctive immunotherapy in cancer

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Hypoxia Promotes Immune Evasion by Triggering β-Glucan Masking on the Candida albicans Cell Surface via Mitochondrial and cAMP-Protein Kinase A Signaling

article by Arnab Pradhan et al published 6 November 2018 in mBio

ICU-acquired immunosuppression and the risk for secondary fungal infections.

scientific article published on 18 August 2010

IFN-gamma is not induced through increased plasma concentrations of interleukin-12/interleukin-18 during human endotoxemia

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IFN-γ-stimulated neutrophils suppress lymphocyte proliferation through expression of PD-L1.

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IL-1 family nomenclature

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IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans

scientific article published on 18 February 2014

IL-18 Serum Concentration Is Markedly Elevated in Acute EBV Infection and Can Serve as a Marker for Disease Severity ⬇️

scientific article published on June 11, 2012

IL-1beta processing in host defense: beyond the inflammasomes

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IL-1β processing in mechanical ventilation-induced inflammation is dependent on neutrophil factors rather than caspase-1

scientific article published on 29 October 2013

IL-1β/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections

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IL-32 promoter SNP rs4786370 predisposes to modified lipoprotein profiles in patients with rheumatoid arthritis

scientific article published on 30 January 2017

IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism

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IL-32, a proinflammatory cytokine in rheumatoid arthritis ⬇️

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IL-37 protects against obesity-induced inflammation and insulin resistance.

scientific article published on 3 September 2014

IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist

scientific article published on 6 February 2012

IMPACT OF COMORBIDITIES ON THE PERFORMANCE OF INTERFERON GAMMA RELEASE ASSAY IN A GREEK ELDERLY POPULATION WITHOUT OVERT IMMUNODEFICIENCY

scientific article published on 03 July 2020

INTERACTING NON-SPECIFIC IMMUNOLOGICAL EFFECTS OF BCG AND Tdapf VACCINATIONS: AN EXPLORATIVE RANDOMIZED TRIAL

scientific article published on 01 January 2020

IRGM gene polymorphisms and risk of gastric cancer.

scientific article published in July 2012

Identification of Discriminating Metabolic Pathways and Metabolites in Human PBMCs Stimulated by Various Pathogenic Agents.

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Immune Parameters for Diagnosis and Treatment Monitoring in Invasive Mold Infection

scientific article published on 16 December 2019

Immune cell characteristics and cytokine responses in adult HIV-negative tuberculous meningitis: an observational cohort study

scientific article published in Scientific Reports

Immune defects in patients with pulmonary <i>Mycobacterium abscessus</i> disease without cystic fibrosis

scientific article published on 01 October 2020

Immune defence against Candida fungal infections

scientific article published on 21 September 2015

Immune memory characteristics of innate lymphoid cells

scientific article published on 01 June 2019

Immune recognition of Candida albicans beta-glucan by dectin-1.

scientific article published on 31 October 2007

Immune recognition of putative alien microbial structures: Host-pathogen interactions in the age of space travel

scientific article published on 30 January 2020

Immune response to Aspergillus fumigatus in compromised hosts: from bedside to bench

scientific article published on January 2011

Immune responses in relation to the type and time of thermal injury: an experimental study.

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Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors

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Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidaemia.

scientific article published on 08 September 2014

Immunodeficiency and Genetic Defects of Pattern-Recognition Receptors ⬇️

scientific article published on January 6, 2011

Immunogenicity of the Q fever skin test

scientific article published on 15 March 2014

Immunologic defects in severe mucocutaneous HSV-2 infections: Response to IFN-γ therapy

scientific article published on 7 April 2016

Immunological memory in innate immunity.

scientific article published on 5 December 2013

Immunological memory: lessons from the past and a look to the future

scientific article published in February 2016

Immunology of Fungal Infections

scholarly article published 2007

Immunometabolic Pathways in BCG-Induced Trained Immunity

scientific article published on December 2016

Immunometabolic circuits in trained immunity

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Immunometabolic control of trained immunity

scientific article published on 02 September 2020

Immunometabolism orchestrates training of innate immunity in atherosclerosis

scientific article published on 01 July 2019

Immunomodulatory adjunctive treatment options for Ebola virus disease patients

scientific article published on 2 April 2015

Immunotherapeutic approaches to treatment of fungal diseases.

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Immunotherapy for the Adjunctive Treatment of Sepsis: From Immunosuppression to Immunostimulation. Time for a Paradigm Change? ⬇️

scientific article published on June 15, 2013

Immunotherapy with G-CSF in patients with chronic mucocutaneous candidiasis

scientific article published on 18 May 2015

Immunotherapy: a potential adjunctive treatment for fungal infection

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Impact of Historic Migrations and Evolutionary Processes on Human Immunity

scientific article published on 27 November 2019

Impaired dendritic cell function in Crohn's disease patients with NOD2 3020insC mutation

scientific article published on 3 February 2006

Improved insulin sensitivity by anti-TNFalpha antibody treatment in patients with rheumatic diseases

scientific article published on April 2007

In Vitro Experimental Model of Trained Innate Immunity in Human Primary Monocytes

scientific article published on 12 October 2016

Increase of Plasminogen Activator Inhibitor-1 and Decrease of Transforming Growth Factor-B1 in Children with Dengue Haemorrhagic Fever in Indonesia ⬇️

scientific article published on January 28, 2011

Increased NEFA levels reduce blood Mg2+ in hypertriacylglycerolaemic states via direct binding of NEFA to Mg2

scientific article published on 13 November 2018

Increased Plasma Heparanase Activity in COVID-19 Patients

scientific article published on 06 October 2020

Increased Soluble Interleukin-2 Receptor Concentrations in Patients with Insulin-dependent Diabetes Mellitus

scientific article published on 01 February 1997

Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes

scientific article published on 02 May 2019

Individual LPS responsiveness depends on the variation of toll-like receptor (TLR) expression level

scientific article published on 01 November 2007

Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome

Induction of Trained Innate Immunity in Human Monocytes by Bovine Milk and Milk-Derived Immunoglobulin G

scientific article published on 27 September 2018

Induction of innate immune memory: the role of cellular metabolism

scientific article published on 19 September 2018

Infection withMycobacterium tuberculosisBeijing Genotype Strains Is Associated with Polymorphisms inSLC11A1/NRAMP1in Indonesian Patients with Tuberculosis

scholarly article by Reinout van Crevel et al published December 2009 in Journal of Infectious Diseases

Inflammasome activation and IL-1β and IL-18 processing during infection

scientific article published on 18 February 2011

Inflammasome inhibition: putting out the fire

scientific article published on April 2015

Inflammasome is a central player in the induction of obesity and insulin resistance

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Inflammasome-independent modulation of cytokine response by autophagy in human cells

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Inflammasome-independent regulation of IL-1-family cytokines

scientific article published on 10 December 2014

Inflammasome-independent role of apoptosis-associated speck-like protein containing a CARD (ASC) in T cell priming is critical for collagen-induced arthritis

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Inflammation in the subcutaneous adipose tissue does not attenuate endothelial function in subjects with diabetes mellitus and subjects with dyslipidaemia and hypertension: A cross-sectional study

scientific article published on 02 July 2018

Inflammation links excess fat to insulin resistance: the role of the interleukin‐1 family ⬇️

scientific article published on September 1, 2012

Inflammation-dependent secretion and splicing of IL-32{gamma} in rheumatoid arthritis

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Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta

scientific article published on December 2009

Influence of endogenous pro-inflammatory cytokines on neutrophil-mediated damage of Candida albicans pseudohyphae, quantified in a modified tetrazolium dye assay.

scientific article published in September 2005

Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts

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Inherited CARD9 deficiency in otherwise healthy children and adults with Candida species-induced meningoencephalitis, colitis, or both

scientific article published on 19 February 2015

Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance

scientific article published on 06 November 2018

Inhibition of Toll-like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis.

scientific article published in September 2007

Inhibition of caspase-1 activation in Gram-negative sepsis and experimental endotoxemia

scientific article published on 18 January 2011

Innate Immune Recognition of Mycobacterium tuberculosis ⬇️

scientific article published on 07 April 2011

Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity

scientific article published on 01 October 2020

Innate Immunity to Candida Infections

Innate and Adaptive Immune Memory: an Evolutionary Continuum in the Host's Response to Pathogens

scientific article published on 01 January 2019

Innate immune cell activation and epigenetic remodeling in symptomatic and asymptomatic atherosclerosis in humans in vivo

scientific article published on 12 October 2016

Innate immune mechanisms for recognition and uptake of Candida species

scientific article published on 11 August 2010

Innate immune memory: An evolutionary perspective.

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Innate immune memory: Implications for host responses to damage-associated molecular patterns

scientific article published on 11 March 2016

Innate immune memory: a paradigm shift in understanding host defense.

scientific article published in June 2015

Innate immune memory: implications for development of pediatric immunomodulatory agents and adjuvanted vaccines

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Innate immune memory: towards a better understanding of host defense mechanisms

scientific article published on 12 March 2014

Innate immunity networks during infection with Borrelia burgdorferi

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Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy

scientific article published on 18 June 2015

Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response

scientific article published on 06 April 2020

Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses

scientific article published on 21 May 2018

Integrative Genomics-Based Discovery of Novel Regulators of the Innate Antiviral Response

scientific article published on 20 October 2015

Intensive insulin therapy does not alter the inflammatory response in patients undergoing coronary artery bypass grafting: a randomized controlled trial [ISRCTN95608630].

scientific article

Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi

scientific article published on 4 July 2016

Interferon-gamma Immunotherapy in a Patient With Refractory Disseminated Candidiasis.

scientific article published on 15 September 2015

Interferon-gamma as adjunctive immunotherapy for invasive fungal infections: a case series

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Interferon-γ and CXCL10 responses related to complaints in patients with Q fever fatigue syndrome.

scientific article published on 26 May 2018

Interleukin 32 (IL-32) contains a typical α-helix bundle structure that resembles focal adhesion targeting region of focal adhesion kinase-1.

scientific article

Interleukin-1 receptor-associated kinase 4 links innate immunity to the pathogenesis of rheumatoid arthritis

scientific article published in June 2009

Interleukin-18 does not modulate the acute-phase response

scientific article

Interleukin-1β activation during acute joint inflammation: a limited role for the NLRP3 inflammasome in vivo

scientific article published on 22 December 2010

Interleukin-1β in innate inflammation, autophagy and immunity

scientific article published on 22 November 2013

Interleukin-32 in chronic inflammatory conditions is associated with a higher risk of cardiovascular diseases

scientific article

Interleukin-32 induces the differentiation of monocytes into macrophage-like cells

scholarly article

Interleukin-32 upregulates the expression of ABCA1 and ABCG1 resulting in reduced intracellular lipid concentrations in primary human hepatocytes

scientific article published on 2 March 2018

Interleukin-32: A predominantly intracellular proinflammatory mediator that controls cell activation and cell death ⬇️

scientific article published on 09 August 2012

Interplay between Candida albicans and the mammalian innate host defense.

scientific article published on 17 January 2012

Interplay between redox status and inflammasome activation ⬇️

scientific article published on September 29, 2011

Interplay between thyroid cancer cells and macrophages: effects on IL-32 mediated cell death and thyroid cancer cell migration

scientific article published on 14 June 2019

Intracellular Alarmins: Hidden dangers signals crucial for cancer, host defense and inflammatory processes

scientific article published on 01 August 2018

Involvement of Lactate and Pyruvate in the Anti-Inflammatory Effects Exerted by Voluntary Activation of the Sympathetic Nervous System

scientific article published on 10 April 2020

Is non-response to fluconazole maintenance therapy for recurrent Candida vaginitis related to sensitization to atopic reactions?

scientific article

Iso-osmolar prehydration shifts the cytokine response towards a more anti-inflammatory balance in human endotoxemia.

scientific article

Itaconate as an immune modulator

scientific article published on 24 June 2019

Kallikrein-kinin blockade in patients with COVID-19 to prevent acute respiratory distress syndrome

scientific article published on 27 April 2020

Key recent advances in TB vaccine development and understanding of protective immune responses against Mycobacterium tuberculosis

scientific article published on 02 December 2020

LPS-induced release of IL-1 beta, IL-1Ra, IL-6, and TNF-alpha in whole blood from patients with familial hypercholesterolemia: no effect of cholesterol-lowering treatment

scientific article published in February 2006

Lesion size is associated with genetic polymorphisms in TLR1, TLR6, and TIRAP genes in patients with major abscesses and diabetic foot infections

scientific article published on 30 November 2019

Letter by Popa and Netea regarding article, "Angiotensin-converting enzyme inhibition improves vascular function in rheumatoid arthritis".

scientific article

Leukocyte-Released Mediators in Response to Both Bacterial and Fungal Infections Trigger IFN Pathways, Independent of IL-1 and TNF-α, in Endothelial Cells

scientific article published on 25 October 2019

Licensed Bacille Calmette-Guérin (BCG) formulations differ markedly in bacterial viability, RNA content and innate immune activation

scientific article published on 28 January 2020

LifeTime and improving European healthcare through cell-based interceptive medicine

scientific article published on 07 September 2020

Limited humoral and cellular responses to Q fever vaccination in older adults with risk factors for chronic Q fever

scientific article published on 22 August 2013

Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity ⬇️

scientific article

Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity

scientific article published on 01 December 2016

Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3.

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Long-Lasting Transcriptional Changes in Circulating Monocytes of Acute Q Fever Patients

scientific article published on 01 July 2019

Long-lasting effects of BCG vaccination on both heterologous Th1/Th17 responses and innate trained immunity

scientific article published on 30 October 2013

Long-term in vitro and in vivo effects of γ-irradiated BCG on innate and adaptive immunity

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Long-term reprogramming of the innate immune system

scientific article published on 12 July 2018

Low induction of proinflammatory cytokines parallels evolutionary success of modern strains within the Mycobacterium tuberculosis Beijing genotype

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Low interleukin-17A production in response to fungal pathogens in patients with chronic granulomatous disease

scientific article published on 22 December 2011

Low prevalence of lactase persistence in Neolithic South-West Europe.

scientific article published on 11 January 2012

Low prevalence of lactase persistence in Neolithic South-West Europe.

scientific article

Low-tidal-volume mechanical ventilation induces a toll-like receptor 4-dependent inflammatory response in healthy mice

scientific article published on September 2008

Lower incidence of Pneumocystis jirovecii pneumonia among Africans in the Netherlands host or environmental factors? ⬇️

scientific article published on April 24, 2013

MAP3K8 (TPL2/COT) affects obesity-induced adipose tissue inflammation without systemic effects in humans and in mice

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MEFV mutations affecting pyrin amino acid 577 cause autosomal dominant autoinflammatory disease

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MST1R mutation as a genetic cause of Lady Windermere syndrome

scientific article published on 18 January 2017

Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice

scientific article published on 02 December 2013

Mannose-binding lectin is a critical factor in systemic complement activation during meningococcal septic shock

scientific article published on November 2009

Mast Cells Induce Vascular Smooth Muscle Cell Apoptosis via a Toll-Like Receptor 4 Activation Pathway

scientific article published on 31 May 2012

Master and commander: epigenetic regulation of macrophages

scientific article published on 15 January 2016

Maternal Priming: Bacillus Calmette-Guérin (BCG) Vaccine Scarring in Mothers Enhances the Survival of Their Child With a BCG Vaccine Scar

scientific article published on 03 February 2019

Mechanical ventilation in healthy mice induces reversible pulmonary and systemic cytokine elevation with preserved alveolar integrity: an in vivo model using clinical relevant ventilation settings

scientific article published on 01 September 2007

Mechanical ventilation induces a Toll/interleukin-1 receptor domain-containing adapter-inducing interferon beta-dependent inflammatory response in healthy mice

scientific article published on 01 October 2009

Medical mycology and fungal immunology: new research perspectives addressing a major world health challenge

scientific article published on December 2016

Metabolic Adaptation Sets the Fate of Regulatory Macrophages

scientific article published on 01 June 2019

Metabolic Age Based on the BBMRI-NL 1H-NMR Metabolomics Repository as Biomarker of Age-related Disease

scientific article published on 14 August 2020

Metabolic Induction of Trained Immunity through the Mevalonate Pathway.

scientific article published in January 2018

Metabolic changes in tumor cells and tumor-associated macrophages: A mutual relationship

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Metabolism impacts upon Candida immunogenicity and pathogenicity at multiple levels

scientific article published on 31 July 2014

Metformin Alters Human Host Responses to Mycobacterium tuberculosis in Healthy Subjects

scientific article published on 01 June 2019

Metformin enhances anti-mycobacterial responses by educating CD8+ T-cell immunometabolic circuits

scientific article published on 16 October 2020

Microbial stimulation of different Toll-like receptor signalling pathways induces diverse metabolic programmes in human monocytes

scientific article published on 19 December 2016

Mimicking Behcet's disease: GM-CSF gain of function mutation in a family suffering from a Behcet's disease-like disorder marked by extreme pathergy

scientific article published on 22 December 2020

Minimal Sex-Differential Modulation of Reactivity to Pathogens and Toll-Like Receptor Ligands following Infant Bacillus Calmette-Guérin Russia Vaccination

scientific article published on 8 September 2017

Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity

scientific article published in January 2018

Modulation of Toll-like receptor 2 (TLR2) and TLR4 responses by Aspergillus fumigatus

scientific article published on 09 February 2009

Modulation of Toll-like receptor ligands and Candida albicans-induced cytokine responses by specific probiotics.

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Modulation of granulocyte kinetics by GM-CSF/IFN-γ in a human LPS rechallenge model

scientific article published on 21 June 2013

Modulation of inflammation by autophagy: Consequences for human disease

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Modulation of inflammation by autophagy: consequences for Crohn's disease.

scientific article published on 16 February 2012

Modulation of inflammatory cytokine production by parenteral lipid emulsions

scientific article published on 01 February 2005

Modulation of lipoprotein plasma concentrations during long-term anti-TNF therapy in patients with active rheumatoid arthritis

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Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases.

scientific article published on 24 October 2017

Monocyte and macrophage immunometabolism in atherosclerosis.

scientific article published on 2 October 2017

Monocytes from neonates and adults have a similar capacity to adapt their cytokine production after previous exposure to BCG and β-glucan

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More than inflammation: interleukin-1beta polymorphisms and the lipid metabolism

scientific article published on May 2011

Mortality in children with complicated severe acute malnutrition is related to intestinal and systemic inflammation: an observational cohort study.

scientific article published on 21 September 2016

Mucosal barrier injury, fever and infection in neutropenic patients with cancer: introducing the paradigm febrile mucositis

scientific article published on 06 September 2014

Multi-omics examination of Q fever fatigue syndrome identifies similarities with chronic fatigue syndrome

scientific article published on 26 November 2020

Multivariate inference of pathway activity in host immunity and response to therapeutics

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Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3.

scientific article published on 13 November 2012

Mycobacterial growth inhibition is associated with trained innate immunity

scientific article published on 20 February 2018

Mycobacterium paratuberculosis is recognized by Toll-like receptors and NOD2.

scientific article published on 25 July 2007

Mycobacterium tuberculosis induces IL-17A responses through TLR4 and dectin-1 and is critically dependent on endogenous IL-1.

scientific article published on 18 March 2010

Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism

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Myeloid cell deficiency of p38γ/p38δ protects against candidiasis and regulates antifungal immunity.

scientific article published on 16 April 2018

NFKB2 polymorphisms associate with the risk of developing rheumatoid arthritis and response to TNF inhibitors: Results from the REPAIR consortium

scientific article published on 09 March 2020

NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis

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NOD2 engagement induces proinflammatory cytokine production, but not apoptosis, in leukocytes isolated from patients with Crohn's disease

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NOD2 mediates anti-inflammatory signals induced by TLR2 ligands: implications for Crohn's disease

scientific article published in July 2004

Native LDL potentiate TNF alpha and IL-8 production by human mononuclear cells.

scientific article published in July 2002

Natural Loss-of-function Mutation of Myeloid Differentiation Protein 88 Disrupts Its Ability to Form Myddosomes ⬇️

scientific article published on February 16, 2011

Neisseria meningitidis can induce pro-inflammatory cytokine production via pathways independent from CD14 and toll-like receptor 4.

scientific article published in October 2002

Neisseria meningitidislipid A mutant LPSs function as LPS antagonists in humans by inhibiting TLR 4-dependent cytokine production ⬇️

scientific article published on November 18, 2010

Neonatal BCG vaccination influences cytokine responses to Toll-like receptor ligands and heterologous antigens.

scientific article published on 3 February 2018

Neutrophil-mediated inhibition of proinflammatory cytokine responses

scientific article published on 10 October 2012

Neutrophils differentially attenuate immune response to Aspergillus infection through complement receptor 3 and induction of myeloperoxidase.

scientific article published on 31 October 2017

New Insights in the Immunobiology of IL-1 Family Members

scientific article published on 08 July 2013

New live attenuated tuberculosis vaccine MTBVAC induces trained immunity and confers protection against experimental lethal pneumonia

scientific article published on 02 April 2020

Non-LPS components of Chlamydia pneumoniae stimulate cytokine production through Toll-like receptor 2-dependent pathways

scientific article published on April 2002

Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion

scientific article published on 22 November 2019

Non-specific Effects of Vaccines and Stunting: Timing May Be Essential

scientific article published on 12 May 2016

Non-specific effects of vaccines: Current evidence and potential implications

scientific article published on 11 July 2018

Normal free interleukin-18 (IL-18) plasma levels in dengue virus infection and the need to measure both total IL-18 and IL-18 binding protein levels

scientific article published on 15 April 2015

Normal responses to specific NOD1 ligands

scientific article published on 01 October 2006

Novel PI3Kγ mutation in a 44-year-old man with chronic infections and chronic pelvic pain

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Novel insights into the biology of interleukin-32 ⬇️

scientific article published on 06 March 2013

Novel strategies for the prevention and treatment of Candida infections: the potential of immunotherapy

scientific article

Novel structural features in Candida albicans hyphal glucan provide a basis for differential innate immune recognition of hyphae versus yeast.

scientific article published on 16 December 2013

Nucleotide oligomerization domain 2 (Nod2) is not involved in the pattern recognition of Candida albicans

scientific article

Nucleotide-binding oligomerization domain-2 modulates specific TLR pathways for the induction of cytokine release

scientific article published in May 2005

OR04-2 Aldosterone Induces Trained Immunity via Fatty Acid Synthesis.

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Oligomeric S100A4 Is Associated With Monocyte Innate Immune Memory and Bypass of Tolerance to Subsequent Stimulation With Lipopolysaccharides

scientific article published on 15 April 2019

One week treatment with the IL-1 receptor antagonist anakinra leads to a sustained improvement in insulin sensitivity in insulin resistant patients with type 1 diabetes mellitus.

scientific article

Opposing Effects of Interleukin-36γ and Interleukin-38 on Trained Immunity

scientific article published in 2023

Opposite effects of Vaccinia and modified Vaccinia Ankara on trained immunity

scientific article published on 05 February 2019

Oral butyrate does not affect innate immunity and islet autoimmunity in individuals with longstanding type 1 diabetes: a randomised controlled trial

scientific article published on 08 January 2020

Origins, admixture and founder lineages in European Roma

scientific article published on 16 September 2015

Outcomes Associated With Use of a Kinin B2 Receptor Antagonist Among Patients With COVID-19

scientific article published on 03 August 2020

Outcomes of controlled human malaria infection after BCG vaccination

scholarly article by Jona Walk et al published 20 February 2019 in Nature Communications

Overcoming immune dysfunction in the elderly: trained immunity as a novel approach

scientific article published on 07 August 2020

Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans ⬇️

scientific article published on 05 August 2016

Oxidized low-density lipoprotein induces long-term proinflammatory cytokine production and foam cell formation via epigenetic reprogramming of monocytes

scientific article published on 05 June 2014

PPAR-alpha dependent regulation of vanin-1 mediates hepatic lipid metabolism

scientific article published on 18 April 2014

PTEN Hamartoma Tumor Syndrome and Immune Dysregulation

Parenteral administration of medium- but not long-chain lipid emulsions may increase the risk for infections by Candida albicans

scientific article published on November 2002

Pathogenesis of invasive candidiasis

scientific article published on October 2010

Pathogenic NLRP3 Inflammasome Activity during Candida Infection Is Negatively Regulated by IL-22 via Activation of NLRC4 and IL-1Ra

scientific article

Patient Susceptibility to Candidiasis-A Potential for Adjunctive Immunotherapy

scientific article published on 9 January 2018

Pattern recognition receptors and their role in invasive aspergillosis ⬇️

scientific article published on 01 December 2012

Persistence of full-length caspase-12 and its relation to malaria in West and Central African populations

scientific article

Personalized medicine in influenza: a bridge too far or the near future?

scientific article published on 2 March 2017

Phagocytosis and intracellular killing of Candida albicans blastoconidia by neutrophils and macrophages: a comparison of different microbiological test systems ⬇️

scientific article published on 01 March 2002

Phagocytosis and intracellular killing of Candida albicans by murine polymorphonuclear neutrophils

scientific article published on 01 January 2012

Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity

scientific article published on 08 May 2020

Phase I/II trial of a combination of anti-CD3/CD7 immunotoxins for steroid-refractory acute graft-versus-host disease

scientific article published on 03 November 2018

Physiological and Genetic Adaptations to Diving in Sea Nomads

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Planarians SET New Paths for Innate Immune Memory.

scientific article published on 5 May 2017

Planning the human variome project: the Spain report.

scientific article published in April 2009

Plasma obtained during human endotoxemia increases endothelial albumin permeability in vitro

scientific article published on 01 April 2006

Plasmodium falciparum infection causes proinflammatory priming of human TLR responses

scientific article published in July 2007

Platelet Integrin αIIbβ3 Activation is Associated with 25-Hydroxyvitamin D Concentrations in Healthy Adults

scientific article published on 05 May 2020

Polymorphisms in autophagy genes and susceptibility to tuberculosis

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Polymorphisms within the <i>TNFSF4</i> and <i>MAPKAPK2</i> Loci Influence the Risk of Developing Invasive Aspergillosis: A Two-Stage Case Control Study in the Context of the aspBIOmics Consortium

scientific article published on 23 December 2020

Population genomics of Mesolithic Scandinavia: Investigating early postglacial migration routes and high-latitude adaptation

scientific article published on 9 January 2018

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

scientific article

Pre-treatment with low-dose endotoxin prolongs survival from experimental lethal endotoxic shock: Benefit for lethal peritonitis by Escherichia coli.

scientific article published on 19 April 2013

Predicting bacterial infection outcomes using single cell RNA-sequencing analysis of human immune cells

scientific article published on 22 July 2019

Predictive value of ex-vivo drug-inhibited cytokine production for clinical response to biologic DMARD therapy in rheumatoid arthritis

scientific article published on 07 February 2019

Predominant Tubular Interleukin-18 Expression in Polyomavirus-Associated Nephropathy

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Presence of Genetic Variants Among Young Men With Severe COVID-19

scientific article published on 24 July 2020

Prevalence of xenotropic murine leukaemia virus-related virus in patients with chronic fatigue syndrome in the Netherlands: retrospective analysis of samples from an established cohort

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Primary immunodeficiencies in cytosolic pattern-recognition receptor pathways: Toward host-directed treatment strategies

scientific article published on 08 July 2020

Pro-inflammatory cytokine response in acute infection.

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Progressive multifocal leukoencephalopathy in an immunocompetent patient

scientific article published on 8 January 2016

Proinflammatory Effects of Hypoglycemia in Humans With or Without Diabetes.

scientific article published on 23 January 2017

Proinflammatory cytokine responses in patients with psoriasis

scientific article published on October 2014

Proinflammatory cytokines and sepsis syndrome: not enough, or too much of a good thing? ⬇️

scientific article published on May 1, 2003

Proinflammatory cytokines in the treatment of bacterial and fungal infections

scientific article published on January 2004

Protective host defense against disseminated candidiasis is impaired in mice expressing human interleukin-37.

scientific article

Publisher Correction: Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations

scientific article published in 2021

Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine

scientific article published on 17 March 2021

Pyruvate dehydrogenase complex stimulation promotes immunometabolic homeostasis and sepsis survival

scientific article published on 09 August 2018

Rare NOX3 Variants Confer Susceptibility to Agranulocytosis During Thyrostatic Treatment of Graves' Disease.

scientific article published on 9 May 2017

Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout

scientific article published on 29 February 2020

Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease

scientific article

Recent common origin, reduced population size, and marked admixture have shaped European Roma genomes

scientific article published on 26 June 2020

Receptor recognition of and immune intracellular pathways for Veillonella parvula lipopolysaccharide

scientific article published on 14 October 2009

Recognition and blocking of innate immunity cells by Candida albicans chitin

scientific article published on 28 February 2011

Recognition of Borrelia burgdorferi by NOD2 is central for the induction of an inflammatory reaction

scientific article

Recognition of Coxiella burnetii by toll-like receptors and nucleotide-binding oligomerization domain-like receptors

scientific article published on 22 September 2014

Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus

scientific article published in Nature

Recognition of fungal pathogens by toll-like receptors

scientific article published on 01 January 2006

Recombinant interleukin-18 protects against disseminated Candida albicans infection in mice

scientific article published in April 2004

Recombination gives a new insight in the effective population size and the history of the old world human populations

scientific article published in September 2011

Recombination networks as genetic markers in a human variation study of the Old World

scientific article

Reconstructing the population history of European Romani from genome-wide data

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Recurrent Vulvovaginal Candidiasis: An Immunological Perspective

scientific article published on 21 January 2020

Recurrent candidiasis and early-onset gastric cancer in a patient with a genetically defined partial MYD88 defect

scientific article published on 23 December 2015

Reduced concentrations of the B cell cytokine Interleukin 38 are associated with cardiovascular disease risk in overweight subjects

scientific article published on 30 October 2020

Reduced levels of cytosolic DNA sensor AIM2 are associated with impaired cytokine responses in healthy elderly.

scientific article

Redundant role of TLR9 for anti-Candida host defense

scientific article published on 26 June 2008

Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs

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Regulating trained immunity with nanomedicine

scientific article published in 2022

Regulation of Staphylococcus epidermidis-induced IFN-γ in whole human blood: the role of endogenous IL-18, IL-12, IL-1, and TNF

scientific article published on 01 January 2003

Remembering Pathogen Dose: Long-Term Adaptation in Innate Immunity.

scientific article

Reply to: ‘Lack of evidence for intergenerational inheritance of immune resistance to infections’

scientific article published in 2022

Reprogramming of bone marrow myeloid progenitor cells in patients with severe coronary artery disease

scientific article published on 10 November 2020

Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells

scientific article published in 2023

Reversal of immunoparalysis in humans in vivo: a double-blind, placebo-controlled, randomized pilot study.

scientific article published on 19 July 2012

Rewiring cellular metabolism via the AKT/mTOR pathway contributes to host defence against Mycobacterium tuberculosis in human and murine cells

scientific article published on 14 September 2016

Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis

scientific article published on 18 September 2017

Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein

scientific article published on 30 April 2020

Risks of Ruxolitinib in STAT1 Gain-of-Function-Associated Severe Fungal Disease

scientific article published on 22 September 2017

Role of Dectin-2 for host defense against systemic infection with Candida glabrata.

scientific article published on 16 December 2013

Role of Glutamine Metabolism in Host Defense Against Mycobacterium tuberculosis Infection

scientific article published on 01 April 2019

Role of Molecular Biology in Diagnosis and Characterization of Vulvo-Vaginitis in Clinical Practice

scientific article

Role of NOD1 polymorphism in susceptibility and clinical progression of rheumatoid arthritis

scientific article published on 25 January 2013

Role of TLR1 and TLR6 in the host defense against disseminated candidiasis

scientific article published on 22 November 2007

Role of autophagy genetic variants for the risk of Candida infections.

scientific article

Role of genetic variants of autophagy genes in susceptibility for non-medullary thyroid cancer and patients outcome

scientific article

Role of glutathione metabolism in host defense against Borrelia burgdorferi infection

scientific article published on 14 February 2018

Role of interleukin-18 in host defense against disseminated Candida albicans infection

scientific article

Role of interleukin-23 (IL-23) receptor signaling for IL-17 responses in human Lyme disease

scientific article published on 6 September 2011

Role of the Candida albicans MNN1 gene family in cell wall structure and virulence.

scientific article

Role of the Mycobiome in Human Acute Graft-versus-Host Disease ⬇️

scientific article published on November 15, 2012

Roles of trained immunity in the pathogenesis of cholangiopathies: a novel therapeutic target

scientific article published on 28 May 2020

STAT1 hyperphosphorylation and defective IL12R/IL23R signaling underlie defective immunity in autosomal dominant chronic mucocutaneous candidiasis

scientific article

STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis

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SUCNR1-mediated chemotaxis of macrophages aggravates obesity-induced inflammation and diabetes.

scientific article

Safety and COVID-19 Symptoms in Individuals Recently Vaccinated with BCG: a Retrospective Cohort Study

scientific article published on 05 August 2020

Safety and Efficacy of Anakinra in Severe Hidradenitis Suppurativa: A Randomized Clinical Trial

scientific article

Salmonella septicemia in rheumatoid arthritis patients receiving anti-tumor necrosis factor therapy: association with decreased interferon-gamma production and Toll-like receptor 4 expression

scientific article published in July 2003

Seasonal variation in vitamin D₃ levels is paralleled by changes in the peripheral blood human T cell compartment.

scientific article

Selective regulation of intercellular adhesion molecule-1 expression by interleukin-18 and interleukin-12 on human monocytes

scientific article published on November 2003

Sepsis--theory and therapies

Severe Candida spp. infections: new insights into natural immunity

scientific article published on 03 December 2010

Sex-Specific Regulation of Inflammation and Metabolic Syndrome in Obesity

scientific article published on 28 May 2020

Shared DNA methylation signatures in childhood allergy: the MeDALL study

scientific article published on 15 December 2020

Short-Term Hypoxia Dampens Inflammation in vivo via Enhanced Adenosine Release and Adenosine 2B Receptor Stimulation.

scientific article

Sixteen-Week Physical Activity Intervention in Subjects With Increased Cardiometabolic Risk Shifts Innate Immune Function Towards a Less Proinflammatory State

scientific article published on 18 October 2019

Skin microbiome imbalance in patients with STAT1/STAT3 defects impairs innate host defense responses

scientific article

Soluble uric acid primes TLR-induced proinflammatory cytokine production by human primary cells via inhibition of IL-1Ra

scientific article published on 03 February 2015

Specific and Complex Reprogramming of Cellular Metabolism in Myeloid Cells during Innate Immune Responses

scientific article

Specific in vitro interferon-gamma and IL-2 production as biomarkers during treatment of chronic Q fever

scientific article

Specific interferon γ detection for the diagnosis of previous Q fever

scientific article

Specific pathways mediating inflammasome activation by Candida parapsilosis

scientific article published on 22 February 2017

Steroid hormone-related polymorphisms associate with the development of bone erosions in rheumatoid arthritis and help to predict disease progression: Results from the REPAIR consortium

scientific article published on 15 October 2019

Strong immunity in the early two years of age links to frequent immunization of routine vaccines

scientific article published on 08 August 2020

Subtle immunodeficiencies in nodular-bronchiectatic Mycobacterium avium complex lung disease

scientific article published on 19 October 2020

Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases

scientific article published on 14 January 2015

Survival after multiple traumas is associated with improved outcomes from gram-negative sepsis: Clinical and experimental evidence

scientific article published on 5 November 2016

Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors.

scientific article published on February 2008

Systemic over-release of interleukin-17 in acute kidney injury after septic shock: Clinical and experimental evidence

scientific article published on 8 August 2016

T Cell Metabolism Has Evolved to Tolerate Tuberculosis

scientific article published on 01 September 2018

T-Cell Lymphopenia in Patients with Advanced Thyroid Carcinoma Is Associated with Poor Prognosis

scientific article published on 03 January 2019

T-cell Subsets and Antifungal Host Defenses ⬇️

scientific article published on September 30, 2010

TLR-3 is present in human adipocytes, but its signalling is not required for obesity-induced inflammation in adipose tissue in vivo

scientific article

TLR1 polymorphisms in Europeans and spontaneous pregnancy loss.

scientific article published on 16 December 2011

TLR1, TLR2, and TLR6 gene polymorphisms are associated with increased susceptibility to complicated skin and skin structure infections.

scientific article published on 6 February 2014

TLR1/TLR2 Heterodimers Play an Important Role in the Recognition of Borrelia Spirochetes ⬇️

scientific article published on October 5, 2011

TLR2 & Co: a critical analysis of the complex interactions between TLR2 and coreceptors

scientific article published on 29 August 2013

TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans

scientific article

TLR4-mediated podosome loss discriminates gram-negative from gram-positive bacteria in their capacity to induce dendritic cell migration and maturation

scientific article published on 28 December 2009

TLRs of Our Fathers

scientific article

TNFR2 is critical for the stabilization of the CD4+Foxp3+ regulatory T. cell phenotype in the inflammatory environment.

scientific article published on 31 December 2012

TNFalpha and IL-1beta exert no direct vasoactivity in human isolated resistance arteries

scientific article

TREM-1 interaction with the LPS/TLR4 receptor complex

scientific article published on 01 March 2011

TREM-1: intracellular signaling pathways and interaction with pattern recognition receptors ⬇️

scientific article published on October 29, 2012

TREML4 adds fuel to the TLR7 fire

scientific article

Targeting innate immunity for tuberculosis vaccination

scientific article published on 01 September 2019

Targeting of Toll-like receptors: a decade of progress in combating infectious diseases

scientific article published on 28 June 2011

Targeting the interleukin-1 pathway in patients with hematological disorders

scientific article published on 8 May 2017

Tetraspanin CD82 Organizes Dectin-1 into Signaling Domains to Mediate Cellular Responses to Candida albicans

scientific article published on 22 April 2019

Th17 cytokine deficiency in patients with Aspergillus skull base osteomyelitis

scientific article

Th17 responses and host defense against microorganisms: an overview

scientific article published on December 2009

The BNT162b2 mRNA Vaccine Against SARS-CoV-2 Reprograms Both Adaptive and Innate Immune Responses

scientific article published in 2021

The C-type lectin DC-SIGN (CD209) is an antigen-uptake receptor for Candida albicans on dendritic cells

scientific article published in February 2003

The C-type lectin receptor CLECSF8/CLEC4D is a key component of anti-mycobacterial immunity

scientific article published on February 2015

The Candida Th17 response is dependent on mannan- and beta-glucan-induced prostaglandin E2.

scientific article published on 8 November 2010

The Carpathian range represents a weak genetic barrier in South-East Europe

scientific article

The Effect of Rosuvastatin on Markers of Immune Activation in Treatment-Naive Human Immunodeficiency Virus-Patients.

scientific article published on 23 December 2015

The Effects of Selective Hematopoietic Expression of Human IL-37 on Systemic Inflammation and Atherosclerosis in LDLr-Deficient Mice

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The Human Cell Atlas

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The Human Cell Atlas

The IL-36 receptor pathway regulates Aspergillus fumigatus-induced Th1 and Th17 responses

scientific article

The Impact of Central and Peripheral Cyclooxygenase Enzyme Inhibition on Exercise-Induced Elevations in Core Body Temperature.

scientific article published on 26 September 2016

The Inflammasome and Caspase-1 Activation: A New Mechanism Underlying Increased Inflammatory Activity in Human Visceral Adipose Tissue ⬇️

scientific article published on August 23, 2011

The Inflammatory response induced by aspartic proteases of Candida albicans is independent of proteolytic activity

scientific article published on 16 August 2010

The Influence of Concentration/Meditation on Autonomic Nervous System Activity and the Innate Immune Response

scientific article published on 01 June 2012

The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis

scientific article published on 01 September 2018

The Inter-Relationship of Platelets with Interleukin-1β-Mediated Inflammation in Humans

scientific article published on 19 November 2018

The Interleukin-1 Family

The Intersection of Epigenetics and Metabolism in Trained Immunity

scientific article published on 10 November 2020

The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity

scientific article published on 04 October 2018

The Janus face of Bartonella quintana recognition by Toll-like receptors (TLRs): a review

scientific article published on 08 September 2008

The MTHFD1 c.1958 G>A polymorphism and recurrent spontaneous abortions

scientific article published on 24 March 2010

The NLRP1-IL18 Connection: A Stab in the Back of Obesity-Induced Inflammation

scientific article

The NOD2 receptor is crucial for immune responses towards New World Leishmania species

scientific article published on 9 November 2017

The Potential Role of Trained Immunity in Autoimmune and Autoinflammatory Disorders

scientific article published on 20 February 2018

The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections

scientific article published on 13 January 2015

The Role of Dectin-2 for Host Defense Against Disseminated Candidiasis

scientific article published on 27 January 2016

The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan

scientific article published on 01 April 2020

The Toll-like receptor 4 Asp299Gly functional variant is associated with decreased rheumatoid arthritis disease susceptibility but does not influence disease severity and/or outcome

scientific article published in March 2004

The Y238X stop codon polymorphism in the human β-glucan receptor dectin-1 and susceptibility to invasive aspergillosis

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The anti-CD20 antibody Rituximab reduces the Th17 response

The anti-CD20 antibody rituximab reduces the Th17 cell response

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The bacteriome-mycobiome interaction and antifungal host defense

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The causes and consequences of variation in human cytokine production in health

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The changing face of febrile neutropenia-from monotherapy to moulds to mucositis. Mucositis: from febrile neutropenia to febrile mucositis

scientific article published on May 2009

The classical CD14⁺⁺ CD16⁻ monocytes, but not the patrolling CD14⁺ CD16⁺ monocytes, promote Th17 responses to Candida albicans

scientific article published on 30 August 2011

The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans

scientific article published on 29 April 2011

The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases.

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The effect of BCG vaccination on alveolar macrophages obtained from induced sputum from healthy volunteers

scientific article published on 10 June 2020

The effect of host genetics on the gut microbiome

scientific article published on 03 October 2016

The effect of hyperglycaemia on in vitro cytokine production and macrophage infection with Mycobacterium tuberculosis

scientific article published on 9 February 2015

The effect of the ATG16L1 Thr300Ala polymorphism on susceptibility and outcome of patients with epithelial cell-derived thyroid carcinoma

scientific article published on 03 May 2012

The effect of the interleukin-1 cytokine family members IL-1F6 and IL-1F8 on adipocyte differentiation

scientific article published on 18 March 2010

The effects of in vivo B-cell depleting therapy on ex-vivo cytokine production

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The effects of orally administered Beta-glucan on innate immune responses in humans, a randomized open-label intervention pilot-study

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The effects of signal transducer and activator of transcription three mutations on human platelets.

scientific article published on 29 September 2017

The epigenetic memory of monocytes and macrophages as a novel drug target in atherosclerosis

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The evolutionary history of TLR4 polymorphisms in Europe

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The fecal and mucosal microbiome in acute appendicitis patients: an observational study

scientific article published on 21 January 2019

The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists

scientific article published on 22 August 2005

The genetics of East African populations: a Nilo-Saharan component in the African genetic landscape

scientific article (publication date: 28 May 2015)

The immunopathology of sepsis and potential therapeutic targets

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The impact of human single nucleotide polymorphisms on Bacillus Calmette-Guérin responses

scientific article published on 18 August 2020

The impact of pre-existing thyroid diseases on susceptibility to respiratory infections or self-reported sickness during the SARS-CoV-2 pandemic

scientific article published in 2022

The impact of sex hormones on BCG-induced trained immunity

scientific article published on 01 September 2018

The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

scientific article published on 24 November 2020

The incidence of acute graft-versus-host disease increases with Candida colonization depending the dectin-1 gene status

scientific article published on 10 May 2010

The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis.

scientific article published on 04 July 2011

The inflammasome puts obesity in the danger zone

scientific article published on January 2012

The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity

scientific article published on December 2010

The influence of dietary fish-oil supplementation on cutaneous Leishmania amazonensis infection in mice

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The influence of neonatal Bacille Calmette-Guérin (BCG) immunisation on heterologous vaccine responses in infants

scientific article published on 29 May 2019

The interplay between central metabolism and innate immune responses

scientific article published on 23 June 2014

The interplay between inflammasome activation and antifungal host defense

scientific article published on May 2015

The loss of functional caspase-12 in Europe is a pre-neolithic event.

scientific article

The macrophage mannose receptor induces IL-17 in response to Candida albicans.

scientific article published in April 2009

The mineralocorticoid receptor as a modulator of innate immunity and atherosclerosis

scientific article published on 01 June 2018

The role of NLRs and TLRs in the activation of the inflammasome

scientific article published in December 2008

The role of TNF-alpha in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk

scientific article published on 2 January 2007

The role of Toll-like receptor 10 in modulation of trained immunity

scientific article published on 26 November 2019

The role of Toll-like receptors and C-type lectins for vaccination against Candida albicans

scientific article

The role of autophagy in host defence against Mycobacterium tuberculosis infection ⬇️

scientific article published on 09 June 2012

The role of endogenous interleukin (IL)-18, IL-12, IL-1beta, and tumor necrosis factor-alpha in the production of interferon-gamma induced by Candida albicans in human whole-blood cultures

scientific article published on 11 March 2002

The role of the interleukin-1 family in trained immunity

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The role of toll-like receptor (TLR) 2 and TLR4 in the host defense against disseminated candidiasis

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The shaping of immunological responses through natural selection after the Roma Diaspora

scientific article published on 30 September 2020

The specifics of innate immune memory

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The tetraspanin protein CD37 regulates IgA responses and anti-fungal immunity

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The toll-like receptor 4 Asp299Gly variant and tuberculosis susceptibility in HIV-infected patients in Tanzania

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Therapeutic targeting of trained immunity

scientific article published on 01 July 2019

Tissue metabolic changes drive cytokine responses to Mycobacterium tuberculosis.

scientific article published on 3 April 2018

Toll-Like Receptors and Inflammasomes

Toll-like receptor 1 polymorphisms increase susceptibility to candidemia.

scientific article published on February 2012

Toll-like receptor 2 controls expansion and function of regulatory T cells

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Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells

scientific article published in March 2004

Toll-like receptor 4 Asp299Gly/Thr399Ile polymorphisms are a risk factor for Candida bloodstream infection

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Toll-like receptor 4 polymorphisms in dengue virus-infected children

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Toll-like receptor triggering in cord blood mesenchymal stem cells

scientific article published on September 2009

Toll-like receptor triggering in cord blood mesenchymal stem cells

scholarly article by Lieke C.J. van den Berk et al published 29 January 2010 in Journal of Cellular and Molecular Medicine

Toll-like receptors and chronic inflammation in rheumatic diseases: new developments

scientific article published on 12 May 2016

Toll-like receptors and the host defense against microbial pathogens: bringing specificity to the innate-immune system

scientific article published on 14 January 2004

Toll-like receptors as an escape mechanism from the host defense

scientific article published on 01 November 2004

Toll-like receptors on regulatory T cells: expanding immune regulation

scientific article published on 30 June 2006

Toward identification of the genetic risk profile for cryptococcal disease in HIV-infected patients

scientific article published on 15 October 2013

Towards a role of interleukin-32 in atherosclerosis ⬇️

scientific article published on May 30, 2013

Trained Immunity Characteristics Are Associated With Progressive Cerebral Small Vessel Disease

scientific article published on 01 December 2018

Trained Immunity and Local Innate Immune Memory in the Lung

scientific article published on 01 November 2018

Trained Immunity in Atherosclerotic Cardiovascular Disease

scientific article published on 05 November 2020

Trained Immunity-Based Vaccines: A New Paradigm for the Development of Broad-Spectrum Anti-infectious Formulations

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Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition

scientific article published on 01 October 2020

Trained Immunity: An Ancient Way of Remembering

scientific article published on March 2017

Trained Immunity: Linking Obesity and Cardiovascular Disease across the Life-Course?

scientific article published on 08 February 2020

Trained Immunity: Long-Term Adaptation in Innate Immune Responses

scientific article published on 22 October 2020

Trained Immunity: a Tool for Reducing Susceptibility to and the Severity of SARS-CoV-2 Infection

scientific article published on 04 May 2020

Trained Innate Immunity as a Novel Mechanism Linking Infection and the Development of Atherosclerosis.

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Trained Innate Immunity, Epigenetics, and Covid-19

scientific article published on 01 September 2020

Trained immunity as a molecular mechanism for BCG immunotherapy in bladder cancer

scientific article published on 16 July 2020

Trained immunity as a novel approach against COVID-19 with a focus on Bacillus Calmette-Guérin vaccine: mechanisms, challenges and perspectives

scientific article published on 22 December 2020

Trained immunity as a novel therapeutic strategy

scientific article published on 24 April 2018

Trained immunity confers broad-spectrum protection against bacterial infections

scientific article published on 31 December 2019

Trained immunity in organ transplantation

scientific article published on 28 October 2019

Trained immunity or tolerance: opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors.

scientific article published on 12 February 2014

Trained immunity, tolerance, priming and differentiation: distinct immunological processes

scientific article published on 08 December 2020

Trained immunity: A program of innate immune memory in health and disease.

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Trained immunity: A smart way to enhance innate immune defence

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Trained immunity: a memory for innate host defense

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Trained immunity: consequences for the heterologous effects of BCG vaccination

scientific article published on January 2015

Trained innate immunity and atherosclerosis

scientific article published on December 2013

Trained innate immunity as a mechanistic link between sepsis and atherosclerosis

scientific article published on 25 November 2014

Trained innate immunity as underlying mechanism for the long-term, nonspecific effects of vaccines

scientific article published on 06 July 2015

Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme

scientific article published in 2021

Training innate immunity: the changing concept of immunological memory in innate host defence ⬇️

scientific article published on August 1, 2013

Transcriptional and functional insights into the host immune response against the emerging fungal pathogen Candida auris

scientific article published on 24 August 2020

Transcriptional and inflammasome-mediated pathways for the induction of IL-1beta production by Mycobacterium tuberculosis.

scientific article

Transcriptional and metabolic reprogramming induce an inflammatory phenotype in non-medullary thyroid carcinoma-induced macrophages.

scientific article published on 9 September 2016

Translating the role of vitamin D3in infectious diseases ⬇️

scientific article published on 05 February 2012

Transmissible Mycobacterium tuberculosis Strains Share Genetic Markers and Immune Phenotypes.

scientific article published on 20 December 2016

Transmission of trained immunity and heterologous resistance to infections across generations

scientific article published in 2021

Treatment With Acetylsalicylic Acid Reverses Endotoxin Tolerance in Humans In Vivo: A Randomized Placebo-Controlled Study

Treatment of candidiasis: insights from host genetics ⬇️

scientific article published on August 1, 2012

Treatment of intra-abdominal abscesses caused by Candida albicans with antifungal agents and recombinant murine granulocyte colony-stimulating factor

scientific article

Treatment options for chronic mucocutaneous candidiasis

scientific article published on 6 May 2016

Treatment with Anakinra Improves Disposition Index But Not Insulin Sensitivity in Nondiabetic Subjects with the Metabolic Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study ⬇️

scientific article published on April 20, 2011

Treatment with Statins Does Not Revert Trained Immunity in Patients with Familial Hypercholesterolemia

scientific article published on 13 June 2019

Triggering receptor expressed on myeloid cells-1 (TREM-1) amplifies the signals induced by the NACHT-LRR (NLR) pattern recognition receptors

scientific article

Tumour necrosis factor alpha-driven IL-32 expression in rheumatoid arthritis synovial tissue amplifies an inflammatory cascade ⬇️

scholarly article by B. Heinhuis et al published April 2011 in Annals of the Rheumatic Diseases

Two Randomized Controlled Trials of Bacillus Calmette-Guérin Vaccination to reduce absenteeism among health care workers and hospital admission by elderly persons during the COVID-19 pandemic: A structured summary of the study protocols for two rand

scientific article published on 05 June 2020

Two patients with cryptococcal meningitis and idiopathic CD4 lymphopenia: defective cytokine production and reversal by recombinant interferon- gamma therapy

scientific article published on 05 October 2004

Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation

scientific article published on October 2015

Understanding human immune function using the resources from the Human Functional Genomics Project

scientific article published on August 2016

Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses.

scientific article published on 14 January 2018

Urban living in healthy Tanzanians is associated with an inflammatory status driven by dietary and metabolic changes

scientific article published in 2021

Uric acid priming in human monocytes is driven by the AKT-PRAS40 autophagy pathway

scientific article published on 8 May 2017

Using BCG vaccine to enhance non-specific protection of health care workers during the COVID-19 pandemic: A structured summary of a study protocol for a randomised controlled trial in Denmark

scientific article published on 17 September 2020

Utility of immune response-derived biomarkers in the differential diagnosis of inflammatory disorders

scientific article published on 28 September 2015

Variable recognition of Candida albicans strains by TLR4 and lectin recognition receptors.

scientific article published in November 2010

Variation in genes of β-glucan recognition pathway and susceptibility to opportunistic infections in HIV-positive patients

scientific article

Variation of growth in the production of the BCG vaccine and the association with the immune response. An observational study within a randomised trial

scientific article published on 10 March 2015

Vasculometabolic and Inflammatory Effects of Aldosterone in Obesity

scientific article published on 12 June 2020

Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity

scientific article published on December 2016

Vildagliptin Improves Endothelium-Dependent Vasodilatation in Type 2 Diabetes ⬇️

scientific article published on July 25, 2011

Vitamin A induces inhibitory histone methylation modifications and down-regulates trained immunity in human monocytes

Vitamin D3 down-regulates proinflammatory cytokine response to Mycobacterium tuberculosis through pattern recognition receptors while inducing protective cathelicidin production ⬇️

scientific article published on May 17, 2011

Voriconazole or amphotericin B as primary therapy yields distinct early serum galactomannan trends related to outcomes in invasive aspergillosis

scientific article (publication date: 2014)

Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.

scientific article published in January 2018

Whole Blood Profiling of Bacillus Calmette-Guérin-Induced Trained Innate Immunity in Infants Identifies Epidermal Growth Factor, IL-6, Platelet-Derived Growth Factor-AB/BB, and Natural Killer Cell Activation

scientific article

Y-chromosome analysis in individuals bearing the Basarab name of the first dynasty of Wallachian kings

scientific article published in 2012

[Is it possible that BCG vaccine protects against COVID-19?]

scientific article published on 07 October 2020

mTOR Inhibition promotes TTF1-dependent redifferentiation and restores iodine uptake in thyroid carcinoma cell lines

scientific article published on 8 April 2014

mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity.

scientific article

β-Glucan Induces Protective Trained Immunity against Mycobacterium tuberculosis Infection: A Key Role for IL-1

scientific article published on 01 May 2020

β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance

scientific article

β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32

scientific article published on 01 September 2019

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