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List of works by Stefano L. Sensi

A Stage-Based Approach to Therapy in Parkinson's Disease

scientific article published on 20 August 2019

A new mitochondrial fluorescent zinc sensor.

scientific article published in September 2003

A sodium zinc exchange mechanism is mediating extrusion of zinc in mammalian cells.

scientific article published on 27 October 2003

AMPA/kainate receptor-triggered Zn2+ entry into cortical neurons induces mitochondrial Zn2+ uptake and persistent mitochondrial dysfunction.

scientific article published in October 2000

Acidosis enhances toxicity induced by kainate and zinc exposure in aged cultured astrocytes.

scientific article published in October 2006

Acute effects of modafinil on brain resting state networks in young healthy subjects

scientific article (publication date: 2013)

Age-Dependent Modifications of AMPA Receptor Subunit Expression Levels and Related Cognitive Effects in 3xTg-AD Mice

scientific article

Alemtuzumab treatment of multiple sclerosis in real-world clinical practice: A report from a single Italian center

scientific article published on 06 November 2019

Alterations of brain and cerebellar proteomes linked to Aβ and tau pathology in a female triple-transgenic murine model of Alzheimer's disease.

scientific article

Altered Kv2.1 functioning promotes increased excitability in hippocampal neurons of an Alzheimer's disease mouse model.

scientific article

Altered oxidant-mediated intraneuronal zinc mobilization in a triple transgenic mouse model of Alzheimer's disease.

scientific article published on 12 November 2007

Aluminum modulates effects of beta amyloid(1-42) on neuronal calcium homeostasis and mitochondria functioning and is altered in a triple transgenic mouse model of Alzheimer's disease

scientific article

Alzheimer Disease, time to turn the tide

article

Alzheimer's disease, metal ions and metal homeostatic therapy

scientific article published on 17 June 2009

Antioxidant strategies based on tomato-enriched food or pyruvate do not affect disease onset and survival in an animal model of amyotrophic lateral sclerosis

scientific article published on 31 July 2007

Brain monoglyceride lipase participating in endocannabinoid inactivation

scientific article

Characterisation of element profile changes induced by long-term dietary supplementation of zinc in the brain and cerebellum of 3xTg-AD mice by alternated cool and normal plasma ICP-MS ⬇️

scientific article published on November 14, 2012

Characterization of MPP(+)-induced cell death in a dopaminergic neuronal cell line: role of macromolecule synthesis, cytosolic calcium, caspase, and Bcl-2-related proteins.

scientific article published on September 1999

Characterization of resting state activity in MCI individuals.

scientific article published on 20 August 2013

Copper and Zinc Dysregulation in Alzheimer's Disease

scientific article published on 20 October 2018

Decreased Presence of Perforated Synapses in a Triple-Transgenic Mouse Model of Alzheimer's Disease

scientific article published on 01 April 2008

Dietary zinc supplementation of 3xTg-AD mice increases BDNF levels and prevents cognitive deficits as well as mitochondrial dysfunction

scientific article

Early and sustained altered expression of aging-related genes in young 3xTg-AD mice

scientific article published on 13 February 2014

Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice

scientific article

Effects of long-term treatment with pioglitazone on cognition and glucose metabolism of PS1-KI, 3xTg-AD, and wild-type mice ⬇️

scientific article published on December 20, 2012

Effects of non-pharmacological or pharmacological interventions on cognition and brain plasticity of aging individuals.

scientific article

Elevated plasma ceramide levels in post-menopausal women: a cross-sectional study

scientific article published on 01 January 2019

Exenatide Reverts the High-Fat-Diet-Induced Impairment of BDNF Signaling and Inflammatory Response in an Animal Model of Alzheimer's Disease

scientific article published on 01 January 2019

Exenatide exerts cognitive effects by modulating the BDNF-TrkB neurotrophic axis in adult mice

scientific article published on 19 December 2017

Exenatide promotes cognitive enhancement and positive brain metabolic changes in PS1-KI mice but has no effects in 3xTg-AD animals.

scientific article published on 2 May 2013

Functional signature of conversion of patients with mild cognitive impairment

scientific article published on 12 October 2018

Glutamate triggers preferential Zn2+ flux through Ca2+ permeable AMPA channels and consequent ROS production.

scientific article published on June 1999

Hallucinations, somatic-functional disorders of PD-DLB as expressions of thalamic dysfunction

scientific article published on 15 July 2019

Heavy metal ions in normal physiology, toxic stress, and cytoprotection.

scientific article published on 4 May 2007

Influence of APOE and RNF219 on Behavioral and Cognitive Features of Female Patients Affected by Mild Cognitive Impairment or Alzheimer's Disease.

scientific article

Inhibition of de novo ceramide biosynthesis affects aging phenotype in an in vitro model of neuronal senescence

scientific article published on 29 August 2019

Intracellular zinc is a critical intermediate in the excitotoxic cascade.

scientific article

Left hippocampus-amygdala complex macro- and microstructural variation is associated with BDNF plasma levels in healthy elderly individuals

scientific article published on 26 May 2015

Measurement of Intracellular Free Zinc in Living Neurons ⬇️

scientific article published on January 1, 1997

Measuring zinc in living cells. A new generation of sensitive and selective fluorescent probes

scientific article published on 01 May 2002

Mediation of Neuronal Apoptosis by Enhancement of Outward Potassium Current ⬇️

scientific article published on October 3, 1997

Medium-chain plasma acylcarnitines, ketone levels, cognition, and gray matter volumes in healthy elderly, mildly cognitively impaired, or Alzheimer's disease subjects.

scientific article

Method for identifying neuronal cells suffering zinc toxicity by use of a novel fluorescent sensor

scientific article published on 01 October 2004

Microarray analysis on human neuroblastoma cells exposed to aluminum, β(1-42)-amyloid or the β(1-42)-amyloid aluminum complex

scientific article

Mild acidosis enhances AMPA receptor-mediated intracellular zinc mobilization in cortical neurons.

scientific article published on July 2007

Mitochondrial sequestration and Ca(2+)-dependent release of cytosolic Zn(2+) loads in cortical neurons.

scientific article

Modafinil alters intrinsic functional connectivity of the right posterior insula: a pharmacological resting state fMRI study

scientific article

Modafinil-Induced Changes in Functional Connectivity in the Cortex and Cerebellum of Healthy Elderly Subjects

scientific article

Modulation of mitochondrial function by endogenous Zn2+ pools.

scientific article

NCLX is an essential component of mitochondrial Na+/Ca2+ exchange

scientific article

New therapeutic targets in Alzheimer's disease: brain deregulation of calcium and zinc ⬇️

scientific article published on June 23, 2011

Nitric oxide reduces Ca(2+) and Zn(2+) influx through voltage-gated Ca(2+) channels and reduces Zn(2+) neurotoxicity

scientific article published on 01 January 2000

Pyruvate prevents the development of age-dependent cognitive deficits in a mouse model of Alzheimer's disease without reducing amyloid and tau pathology

scientific article published on 28 November 2014

Ratiometric-pericam-mt, a novel tool to evaluate intramitochondrial zinc.

scientific article published on 15 April 2009

Rethinking the excitotoxic ionic milieu: the emerging role of Zn(2+) in ischemic neuronal injury.

scientific article published on March 2004

Staurosporine-induced neuronal apoptosis.

scientific article published on October 1995

Subclinical Cognitive and Neuropsychiatric Correlates and Hippocampal Volume Features of Brain White Matter Hyperintensity in Healthy People

scientific article published on 15 October 2020

The Role of Zinc in the Treatment of Wilson's Disease

scientific article published on 18 August 2022

The amyloid cascade hypothesis: an updated critical review

scientific article published in 2023

The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis.

scientific article published on 29 November 2006

The mitochondrial Na+/Ca2+ exchanger upregulates glucose dependent Ca2+ signalling linked to insulin secretion

scientific article

The neurophysiology and pathology of brain zinc

scientific article published on November 2011

The pharmacological perturbation of brain zinc impairs BDNF-related signaling and the cognitive performances of young mice.

scientific article published on 27 June 2018

The thiol-modifying agent N-ethylmaleimide elevates the cytosolic concentration of free Zn(2+) but not of Ca(2+) in murine cortical neurons.

scientific article published on 25 July 2010

Towards Combinatorial Approaches for Preserving Cognitive Fitness in Aging

scientific article published on 18 October 2018

Zinc in the physiology and pathology of the CNS.

scientific article published on 14 October 2009

Zinc pre-treatment enhances NMDAR-mediated excitotoxicity in cultured cortical neurons from SOD1(G93A) mouse, a model of amyotrophic lateral sclerosis.

scientific article published on 5 November 2010

Zn(2+) induces permeability transition pore opening and release of pro-apoptotic peptides from neuronal mitochondria.

scientific article

Zn(2+): a novel ionic mediator of neural injury in brain disease.

scientific article

Zn2+ currents are mediated by calcium-permeable AMPA/kainate channels in cultured murine hippocampal neurones.

scientific article published in August 2002

nNOS(+) striatal neurons, a subpopulation spared in Huntington's Disease, possess functional NMDA receptors but fail to generate mitochondrial ROS in response to an excitotoxic challenge

scientific article published on 16 May 2013

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