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List of works by Thomas Mertens

A new tool linking human cytomegalovirus drug resistance mutations to resistance phenotypes

scientific article

Adoptive transfer and selective reconstitution of streptamer‐selected cytomegalovirus‐specific CD8+ T cells leads to virus clearance in patients after allogeneic peripheral blood stem cell transplantation ⬇️

scientific article published on December 6, 2010

Analysis of human cytomegalovirus secondary envelopment by advanced electron microscopy ⬇️

scientific article published on December 20, 2012

Antiviral treatment of cytomegalovirus infection and resistant strains

scientific article published on 01 February 2009

Assessment of natural killer cell responses to human cytomegalovirus-infected macrophages

scientific article published on January 2013

Beschluss der STIKO zur 1. Aktualisierung der COVID-19-Impfempfehlung und die dazugehörige wissenschaftliche Begründung

scientific article published on 8 January 2021

Cellular Immunity and Active Human Cytomegalovirus Infection in Patients with Septic Shock

scientific article published on 01 October 2007

Constitutive inositol phosphate formation in cytomegalovirus-infected human fibroblasts is due to expression of the chemokine receptor homologue pUS28.

scientific article

Constitutive signaling of the human cytomegalovirus-encoded receptor UL33 differs from that of its rat cytomegalovirus homolog R33 by promiscuous activation of G proteins of the Gq, Gi, and Gs classes.

scientific article published on 30 September 2003

Cytomegalovirus primary envelopment at large nuclear membrane infoldings: what's new?

scientific article published on July 2007

Cytomegalovirus primary envelopment occurs at large infoldings of the inner nuclear membrane.

scientific article published on 27 December 2006

Cytomegalovirus retinitis in a patient treated with anti-tumor necrosis factor alpha antibody therapy for rheumatoid arthritis.

scientific article published on 11 October 2004

Development of a high-throughput colorimetric Zika virus infection assay

scientific article (publication date: 7 February 2017)

Differentiation between Polymorphisms and Resistance-Associated Mutations in Human Cytomegalovirus DNA Polymerase ⬇️

scientific article published on September 27, 2010

Early selection of a new UL97 mutant with a severe defect of ganciclovir phosphorylation after valaciclovir prophylaxis and short-term ganciclovir therapy in a renal transplant recipient.

scientific article published on April 2005

Fast selection of maribavir resistant cytomegalovirus in a bone marrow transplant recipient

scientific article

Fatal reactivation of postnatal cytomegalovirus infection with rapid emergence of ganciclovir resistance in an infant after allogeneic stem cell transplantation

scientific article published on July 2005

Fluorescence-based assay for phenotypic characterization of human cytomegalovirus polymerase mutations regarding drug susceptibility and viral replicative fitness

scientific article

GCV resistance due to the mutation A594P in the cytomegalovirus protein UL97 is partially reconstituted by a second mutation at D605E.

scientific article published in February 2002

Ganciclovir/valganciclovir prophylaxis decreases cytomegalovirus-related events and bronchiolitis obliterans syndrome after lung transplantation.

scientific article published in March 2008

HCMV infection of human vascular smooth muscle cells leads to enhanced expression of functionally intact PDGF β-receptor

scientific article published on 12 April 2005

HCMV-infection in a human arterial organ culture model: effects on cell proliferation and neointimal hyperplasia

scientific article

High variability between results of different in-house tests for cytomegalovirus (CMV) monitoring and a standardized quantitative plasma CMV PCR assay.

scientific article published on June 2002

Hintergrundpapier der STIKO: Evaluation der bestehenden Influenzaimpfempfehlung für Indikationsgruppen und für Senioren (Standardimpfung ab 60 Jahren).

scientific article published on 4 November 2016

Human Cytomegalovirus pUL47 Modulates Tegumentation and Capsid Accumulation at the Viral Assembly Complex

scientific article

Human Macrophages Escape Inhibition of Major Histocompatibility Complex-Dependent Antigen Presentation by Cytomegalovirus and Drive Proliferation and Activation of Memory CD4+ and CD8+ T Cells.

scientific article

Human cytomegalovirus infection impairs endothelial cell chemotaxis by disturbing VEGF signalling and actin polymerization

scientific article published on 16 September 2014

Human cytomegalovirus infection in human renal arteries in vitro

scientific article published in April 2003

Human cytomegalovirus infection of M1 and M2 macrophages triggers inflammation and autologous T-cell proliferation.

scientific article published on 10 October 2012

Human cytomegalovirus paralyzes macrophage motility through down-regulation of chemokine receptors, reorganization of the cytoskeleton, and release of macrophage migration inhibitory factor

scientific article published on January 2009

Human cytomegalovirus tegument protein ppUL35 is important for viral replication and particle formation

scientific article published on March 2005

Human cytomegalovirus-induced NKG2C(hi) CD57(hi) natural killer cells are effectors dependent on humoral antiviral immunity

scientific article published on May 2013

Human cytomegalovirus-induced reduction of extracellular matrix proteins in vascular smooth muscle cell cultures: a pathomechanism in vasculopathies?

scientific article published on 01 October 2006

Identification of the first nonpeptidergic inverse agonist for a constitutively active viral-encoded G protein-coupled receptor

scientific article published on 26 November 2002

Impfen bei Immundefizienz : Anwendungshinweise zu den von der Ständigen Impfkommission empfohlenen Impfungen(I) Grundlagenpapier

scientific article published on 2 May 2017

Improved detection of mutated human cytomegalovirus UL97 by pyrosequencing

scientific article published on 27 September 2010

In vivo/ex vivo T cell depletion for GVHD prophylaxis influences onset and course of active cytomegalovirus infection and disease after BMT

scientific article published on 01 March 1995

Inactivation and Environmental Stability of Zika Virus

scientific article

Influenza vaccination and the end of simplicity

scientific article published on November 2013

Interleukin-2 from Adaptive T Cells Enhances Natural Killer Cell Activity against Human Cytomegalovirus-Infected Macrophages

scientific article published on 8 April 2015

Late HBsAg seroreversion of mutated hepatitis B virus after bone marrow transplantation

scientific article

Major tegument protein pp65 of human cytomegalovirus is required for the incorporation of pUL69 and pUL97 into the virus particle and for viral growth in macrophages

scientific article published on 30 December 2008

Megapinocytosis: a novel endocytic pathway

scientific article published on 6 January 2016

Multimer staining of cytomegalovirus phosphoprotein 65-specific T cells for diagnosis and therapeutic purposes: a comparative study

scientific article published on 01 May 2008

Mutations in the UL97 ORF of ganciclovir-resistant clinical cytomegalovirus isolates differentially affect GCV phosphorylation as determined in a recombinant vaccinia virus system

scientific article published on April 2002

NK Cells from RAG- or DCLRE1C-Deficient Patients Inhibit HCMV

scientific article published on 10 November 2019

Natural killer cells can inhibit the transmission of human cytomegalovirus in cell culture by using mechanisms from innate and adaptive immune responses

scientific article published on 24 December 2014

Naïve T cells are activated by autologous HCMV-infected endothelial cells through NKG2D and can control HCMV transmission in vitro.

scientific article published on 21 November 2017

Nuclear targeting of human cytomegalovirus large tegument protein pUL48 is essential for viral growth

scientific article published on 20 March 2013

Peptide vaccination in the presence of adjuvants in patients after hematopoietic stem cell transplantation with CD4+ T cell reconstitution elicits consistent CD8+ T cell responses

scientific article

Post-pandemic seroprevalence of pandemic influenza A (H1N1) 2009 infection (swine flu) among children <18 years in Germany

scientific article

Protein pUL128 of Human Cytomegalovirus Is Necessary for Monocyte Infection and Blocking of Migration ⬇️

scientific article published on March 2, 2011

Quantitative investigation of murine cytomegalovirus nucleocapsid interaction

scientific article

Report on the 1st international workshop on procedures for the development of evidence-based vaccination recommendations, Berlin, Germany, 22-23 November 2010.

scientific article published on 13 December 2011

Role of the human herpesvirus 6 u69-encoded kinase in the phosphorylation of ganciclovir

scientific article published in September 2002

Single nucleotide polymorphisms of thymidine kinase and DNA polymerase genes in clinical herpes simplex virus type 1 isolates associated with different resistance phenotypes.

scientific article published on 18 April 2014

The 7-transmembrane protein homologue UL78 of the human cytomegalovirus forms oligomers and traffics between the plasma membrane and different intracellular compartments ⬇️

scientific article published on February 12, 2012

The Tegument Protein UL71 of Human Cytomegalovirus Is Involved in Late Envelopment and Affects Multivesicular Bodies ⬇️

scientific article published on February 2, 2011

The UL97 protein kinase of human cytomegalovirus and homologues in other herpesviruses: impact on virus and host.

scientific article published on March 2004

The human cytomegalovirus UL78 gene is highly conserved among clinical isolates, but is dispensable for replication in fibroblasts and a renal artery organ-culture system

scientific article

The immunodominant CD8 T cell response to the human cytomegalovirus tegument phosphoprotein pp65(495-503) epitope critically depends on CD4 T cell help in vaccinated HLA-A*0201 transgenic mice

scientific article published on 01 August 2011

Upregulation of functionally active vascular endothelial growth factor by human cytomegalovirus

scientific article published on 01 January 2005

Varicella-zoster-virus vaccination in immunosuppressed children with rheumatic diseases using a pre-vaccination check list.

scientific article published on 2 March 2018

[Vaccination in Germany - Recommendations of STIKO]

scientific article published on 13 February 2019

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