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List of works by Michael Koomey

A Broad Spectrum Protein Glycosylation System Influences Type II Protein Secretion and Associated Phenotypes in Vibrio cholerae

scientific article published on 03 December 2019

A conserved set of pilin-like molecules controls type IV pilus dynamics and organelle-associated functions in Neisseria gonorrhoeae.

scientific article

A force-dependent switch reverses type IV pilus retraction ⬇️

scholarly article

Adenovirus type 12 VA RNA I. Synthesis in productive infection and gene mapping ⬇️

scientific article published on June 1, 1979

Allelic polymorphisms in a glycosyltransferase gene shape glycan repertoire in the O-linked protein glycosylation system of Neisseria

scientific article published on 08 August 2020

Allelic variation in a simple sequence repeat element of neisserial pglB2 and its consequences for protein expression and protein glycosylation

scientific article published on 31 May 2013

An extended spectrum of target proteins and modification sites in the general O-linked protein glycosylation system in Neisseria gonorrhoeae

scientific article published on 29 October 2012

An inhibitor of DNA binding and uptake events dictates the proficiency of genetic transformation in Neisseria gonorrhoeae: mechanism of action and links to Type IV pilus expression

scientific article published on 01 December 2002

Attachment to and invasion of human fallopian tube mucosa by an IgA1 protease-deficient mutant of Neisseria gonorrhoeae and its wild-type parent.

scientific article published on November 1984

Bacterial pathogenesis: a variation on variation in Lyme disease.

scientific article published on September 1997

Biochemical characterization of the O-linked glycosylation pathway in Neisseria gonorrhoeae responsible for biosynthesis of protein glycans containing N,N'-diacetylbacillosamine

scientific article

Broad spectrum O-linked protein glycosylation in the human pathogen Neisseria gonorrhoeae.

scholarly article

Characterization of a Unique Tetrasaccharide and Distinct Glycoproteome in the O-Linked Protein Glycosylation System of Neisseria elongata subsp. glycolytica

scientific article published on 19 October 2015

Characterization of exogenous bacterial oligosaccharyltransferases in Escherichia coli reveals the potential for O-linked protein glycosylation in Vibrio cholerae and Burkholderia thailandensis.

scientific article

Characterization of the pilF-pilD pilus-assembly locus of Neisseria gonorrhoeae.

scientific article

Competence for natural transformation in Neisseria gonorrhoeae: a model system for studies of horizontal gene transfer

article

Competence for natural transformation in Neisseria gonorrhoeae: components of DNA binding and uptake linked to type IV pilus expression

scientific article

Concerted spatio-temporal dynamics of imported DNA and ComE DNA uptake protein during gonococcal transformation

scientific article

Conservation of genes encoding components of a type IV pilus assembly/two-step protein export pathway in Neisseria gonorrhoeae.

scientific article published on April 1993

Crystallographic structure reveals phosphorylated pilin from Neisseria: phosphoserine sites modify type IV pilus surface chemistry and fibre morphology

scientific article

Cytochrome c-based domain modularity governs genus-level diversification of electron transfer to dissimilatory nitrite reduction.

scientific article published on 11 December 2014

Disrupted Synthesis of a Di-N-acetylated Sugar Perturbs Mature Glycoform Structure and Microheterogeneity in the O-Linked Protein Glycosylation System of Neisseria elongata subsp. glycolytica.

scientific article published on 7 December 2018

Down-regulation of CD46 by piliated Neisseria gonorrhoeae.

scientific article

Dynamics of type IV pili is controlled by switching between multiple states

scientific article

Extended glycan diversity in a bacterial protein glycosylation system linked to allelic polymorphisms and minimal genetic alterations in a glycosyltransferase gene

scientific article published on 29 September 2014

Functional analyses of pilin-like proteins from Francisella tularensis: complementation of type IV pilus phenotypes in Neisseria gonorrhoeae.

scientific article published on 7 May 2009

Gene conversion accounts for pilin structural changes and for reversible piliation "phase" changes in gonococci

scientific article published on 01 January 1987

Gene conversion in Neisseria gonorrhoeae: evidence for its role in pilus antigenic variation ⬇️

scientific article published on June 15, 1992

Gene conversion variations generate structurally distinct pilin polypeptides in Neisseria gonorrhoeae

scientific article

Genetic and biochemical analysis of gonococcal IgA1 protease: cloning in Escherichia coli and construction of mutants of gonococci that fail to produce the activity.

scientific article

Genetic and functional analyses of PptA, a phospho-form transferase targeting type IV pili in Neisseria gonorrhoeae

scientific journal article

Genetic and molecular analyses reveal an evolutionary trajectory for glycan synthesis in a bacterial protein glycosylation system

scientific article

Genetic determinants of genus-level glycan diversity in a bacterial protein glycosylation system

scientific article published on 23 December 2019

Genetic diversity among the T-protein genes of group A streptococci.

scientific article

Genetic, structural, and antigenic analyses of glycan diversity in the O-linked protein glycosylation systems of human Neisseria species

scientific article published on 2 April 2010

Global biochemical and structural analysis of the type IV pilus from the Gram-positive bacterium

scientific article published on 05 March 2019

Gonococcal pilin variants in experimental gonorrhea.

scientific article

Hypomorphic glycosyltransferase alleles and recoding at contingency loci influence glycan microheterogeneity in the protein glycosylation system of Neisseria species

scientific article published on 13 July 2012

Infection of human mucosal tissue by Pseudomonas aeruginosa requires sequential and mutually dependent virulence factors and a novel pilus-associated adhesin.

scientific article

Insights into type IV pilus biogenesis and dynamics from genetic analysis of a C-terminally tagged pilin: a role for O-linked glycosylation.

scientific article

Kiss and Run – Phosphoglycerol Modifications of N. Meningitidis Pili Mediate Detachment ⬇️

scientific article published on April 27, 2011

Microbial genome dynamics in CNS pathogenesis.

scientific article published on 23 March 2007

Modification of type IV pilus-associated epithelial cell adherence and multicellular behavior by the PilU protein of Neisseria gonorrhoeae.

scientific article

Multiple pilus motors cooperate for persistent bacterial movement in two dimensions

scientific article published on 28 April 2010

Neisseria gonorrhoeae O-linked pilin glycosylation: functional analyses define both the biosynthetic pathway and glycan structure.

scientific article

Neisseria gonorrhoeae type IV pili undergo multisite, hierarchical modifications with phosphoethanolamine and phosphocholine requiring an enzyme structurally related to lipopolysaccharide phosphoethanolamine transferases

scientific article published on 05 July 2006

Novel protein substrates of the phospho-form modification system in Neisseria gonorrhoeae and their connection to O-linked protein glycosylation.

scientific article published on 14 November 2011

O-linked glycosylation of the PilA pilin protein of Francisella tularensis: identification of the endogenous protein-targeting oligosaccharyltransferase and characterization of the native oligosaccharide.

scientific article published on 29 July 2011

O-linked protein glycosylation in bacteria: snapshots and current perspectives

scientific article published on 09 May 2019

Phase variation of gonococcal protein II: regulation of gene expression by slipped-strand mispairing of a repetitive DNA sequence.

scientific article published in February 1989

PilP, a pilus biogenesis lipoprotein in Neisseria gonorrhoeae, affects expression of PilQ as a high-molecular-mass multimer.

scientific article published on February 1997

PilT mutations lead to simultaneous defects in competence for natural transformation and twitching motility in piliated Neisseria gonorrhoeae.

scientific article published on July 1998

Pilin expression and processing in pilus mutants of Neisseria gonorrhoeae: critical role of Gly-1 in assembly.

scientific article published in February 1991

Porin protein of Neisseria gonorrhoeae: cloning and gene structure.

scientific article

Prepilin-like molecules in type 4 pilus biogenesis: minor subunits, chaperones or mediators of organelle translocation?

scientific article published on November 1995

Pseudomonas aeruginosa Type IV pilus expression in Neisseria gonorrhoeae: effects of pilin subunit composition on function and organelle dynamics.

scientific article

Regulation of exoprotein expression in Staphylococcus aureus by a locus (sar) distinct from agr ⬇️

scientific article published on July 15, 1992

Release of host-derived membrane vesicles following pilus-mediated adhesion of Neisseria gonorrhoeae

scientific article published on November 2005

Roles of c-type cytochromes in respiration in Neisseria meningitidis.

scientific article published in September 2008

Single amino acid substitutions in the N-terminus of Vibrio cholerae TcpA affect colonization, autoagglutination, and serum resistance.

scientific article

Structural alterations in a component of cytochrome c oxidase and molecular evolution of pathogenic Neisseria in humans

scientific article

Structural alterations in a type IV pilus subunit protein result in concurrent defects in multicellular behaviour and adherence to host tissue.

scientific article

Structural and genetic analyses of glycan O-acetylation in a bacterial protein glycosylation system: evidence for differential effects on glycan chain length

scientific article

Substitutions in the N-terminal alpha helical spine of Neisseria gonorrhoeae pilin affect Type IV pilus assembly, dynamics and associated functions

scientific article published on 27 November 2006

Sweet New Roles for Protein Glycosylation in Prokaryotes.

scientific article published on 21 March 2017

The comP locus of Neisseria gonorrhoeae encodes a type IV prepilin that is dispensable for pilus biogenesis but essential for natural transformation.

scientific article published on March 1999

The pilus colonization factor of pathogenic neisserial species: organelle biogenesis and structure/function relationships--a review.

scientific article published on June 1997

Transcriptional, chemosensory and cell-contact-dependent regulation of type IV pilus expression.

scientific article

Transformation and DNA repair: linkage by DNA recombination

scientific article published on January 2004

Type IV Pilin Post-Translational Modifications Modulate Material Properties of Bacterial Colonies

Type IV pilus assembly proficiency and dynamics influence pilin subunit phospho-form macro- and microheterogeneity in Neisseria gonorrhoeae.

scientific article

Type IV pilus retraction in pathogenic Neisseria is regulated by the PilC proteins.

scientific article

Unique modifications with phosphocholine and phosphoethanolamine define alternate antigenic forms of Neisseria gonorrhoeae type IV pili

scholarly article

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