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List of works by Thomas Graf

A Paracrine Loop between Tumor Cells and Macrophages Is Required for Tumor Cell Migration in Mammary Tumors

article

A functional Ets DNA-binding domain is required to maintain multipotency of hematopoietic progenitors transformed by Myb-Ets

scientific article published in January 1994

A new path to leukemia with WIT

scientific article

A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis

scientific article

A novel type of cellular variant with altered expression of virus-induced cell transformation

scientific article

A plaque assay for avian RNA tumor viruses

A point mutation in the DNA binding domain of the v-myb oncogene of E26 virus confers temperature sensitivity for transformation of myelomonocytic cells

scientific article published in January 1988

A robust and highly efficient immune cell reprogramming system

scientific article

A single amino-acid substitution in the DNA-binding domain of the myb oncogene confers a thermolabile phenotype to E26-transformed myeloid cells

scientific article published in January 1989

A single point mutation in erbA restores the erythroid transforming potential of a mutant avian erythroblastosis virus (AEV) defective in both erbA and erbB oncogenes

scientific article

A single point mutation in the v-ets oncogene affects both erythroid and myelomonocytic cell differentiation

scientific article published in December 1988

A temperature-sensitive mutant of Abelson murine leukemia virus confers inducibility of IgM expression to transformed lymphoid cells.

scientific article published on April 1987

A transcription factor party during blood cell differentiation ⬇️

scientific article published on 01 October 1998

Activation of cMGF expression is a critical step in avian myeloid leukemogenesis.

scientific article published on April 1991

Acute avian leukemia viruses as tools to study hematopoietic cell differentiation

scientific article published on January 1996

An invariant asparagine residue belonging to a highly conserved domain in all protein kinases is instrumental in the protein kinase activity of the v-mil gene product

scientific article

An uphill battle toward pluripotency

scientific article published in September 2009

Antagonism between C/EBPbeta and FOG in eosinophil lineage commitment of multipotent hematopoietic progenitors

scientific article

Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin

scientific article

Assessing the role of hematopoietic plasticity for endothelial and hepatocyte development by non-invasive lineage tracing

scientific article published on 2 December 2004

Autocrine growth induced by src-related oncogenes in transformed chicken myeloid cells

scientific article published on 01 December 1984

Avian leukaemia viruses and haematopoietic cell differentiation.

scientific article published on April 1980

Avian leukemia viruses. Oncogenes and genome structure

scientific article published on June 1982

Avian leukemia viruses: interaction with their target cells in vivo and in vitro

scientific article

Avian myelocytomatosis and erythroblastosis viruses lack the transforming gene src of avian sarcoma viruses

scientific article published on April 1978

B young again

scientific article

BLUEPRINT to decode the epigenetic signature written in blood.

scientific article

Bicistronic retroviral vector reveals capacity of v-erbA to induce erythroleukemia and to co-operate with v-myb.

scientific article

Biochemical properties of oncornavirus polypeptides

scientific article

Biological effects of the v-erbA oncogene in transformation of avian erythroid cells

scientific article published on 01 January 1987

C/EBPa-mediated activation of microRNAs 34a and 223 inhibits Lef1 expression to achieve efficient reprogramming into macrophages

scientific article

C/EBPα Activates Pre-existing and De Novo Macrophage Enhancers during Induced Pre-B Cell Transdifferentiation and Myelopoiesis

scientific article

C/EBPα bypasses cell cycle-dependency during immune cell transdifferentiation

scientific article

C/EBPα induces highly efficient macrophage transdifferentiation of B lymphoma and leukemia cell lines and impairs their tumorigenicity

scientific article

C/EBPα poises B cells for rapid reprogramming into induced pluripotent stem cells.

scientific article

CCAAT/enhancer binding protein alpha (C/EBP(alpha))-induced transdifferentiation of pre-B cells into macrophages involves no overt retrodifferentiation.

scientific article

CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age ⬇️

scientific article published on April 5, 2013

CD41-YFP mice allow in vivo labeling of megakaryocytic cells and reveal a subset of platelets hyperreactive to thrombin stimulation

scientific article published on March 2007

CTCF is dispensable for immune cell transdifferentiation but facilitates an acute inflammatory response

scientific article published on 08 June 2020

Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture

scientific article published on 6 April 2010

Cell transformation by avian defective leukaemia viruses

scientific article published in November 1980

Cell-surface antigens induced by avian RNA tumor viruses: detection by immunoferritin technique

scientific article published in February 1972

Cells transformed by avian myelocytomatosis virus strain CMII contain a 90K gag-related protein

scientific article published on October 1979

Characterization of hematopoietic cells transformed in vitro by AEV-H, a v-erbB-containing avian erythroblastosis virus

scientific article published in January 1985

Characterization of the hematopoietic target cells of AEV, MC29 and AMV avian leukemia viruses

scientific article published in February 1981

Characterization of the hematopoietic target cells of defective avian leukemia viruses by velocity sedimentation and density gradient centrifugation analyses.

scientific article published in January 1981

Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis

scientific article

Chicken "erythroid" cells transformed by the Gag-Myb-Ets-encoding E26 leukemia virus are multipotent

scientific article

Chicken RNA tumor viruses: a model for virus-induced carcinogenesis

scientific article

Chicken hematopoietic cells transformed by seven strains of defective avian leukemia viruses display three distinct phenotypes of differentiation

scientific article published on October 1979

Clonal isolate of the simian sarcoma virus codes for a Gag-related 65,000-dalton protein

scientific article published in October 1981

Co-operation between viral oncogenes in avian erythroid and myeloid leukaemia.

scientific article

Common site of mutation in the erbB gene of avian erythroblastosis virus mutants that are temperature sensitive for transformation

scientific article

Comparison of the microbicidal and muramidase activities of mouse lysozyme M and P

scientific journal article

Cooperative interaction of ets-1 with USF-1 required for HIV-1 enhancer activity in T cells.

scientific article published on March 1998

Cooperativity of viral oncogenes in avian leukaemia

scientific article

Cooperativity of viral oncogenes in the induction of leukemia in an animal model

scientific article published on January 1986

DNA binding by c-Ets-1, but not v-Ets, is repressed by an intramolecular mechanism ⬇️

scientific article published on February 1, 1992

DNA-binding activity is associated with purified myb proteins from AMV and E26 viruses and is temperature-sensitive for E26 ts mutants

scientific article published on 01 April 1985

DNA-binding domain ancestry

scientific article published in Nature

Defective v-erbB genes can be complemented by v-erbA in erythroblast and fibroblast transformation

scientific article published in May 1987

Defectiveness of avian erythroblastosis virus: synthesis of a 75K gag-related protein

scientific article published on January 1979

Detection of avian hematopoietic cell surface antigens with monoclonal antibodies to myeloid cells. Their distribution on normal and leukemic cells of various lineages

scientific article published in February 1983

Determinants of lymphoid-myeloid lineage diversification

scientific article

Differential expression of Rous Sarcoma virus-specific transformation parameters in enucleated cells

scientific article published on August 1978

Differential expression of transformation in rat and chicken cells infected with an avian sarcoma virus ts mutant

scientific article published in November 1973

Differentiation plasticity of hematopoietic cells

scientific article

Distinct C/EBP functions are required for eosinophil lineage commitment and maturation

scientific article

Distinguishable live erythroid and myeloid cells in beta-globin ECFP x lysozyme EGFP mice

scientific article published on 26 September 2002

Dynamic Visualization of Thrombopoiesis Within Bone Marrow

scientific article published in Science

Dynamic changes in the chromatin of the chicken lysozyme gene domain during differentiation of multipotent progenitors to macrophages

scientific article published on May 1995

Dynamics of alternative splicing during somatic cell reprogramming reveals functions for RNA-binding proteins CPSF3, hnRNP UL1, and TIA1

scientific article published on 03 June 2021

E26 leukemia virus converts primitive erythroid cells into cycling multilineage progenitors

scientific article published on 12 September 2002

Early decisions in lymphoid development

scientific article published on 15 February 2007

Early reversible induction of leukotriene synthesis in chicken myelomonocytic cells transformed by a temperature-sensitive mutant of avian leukemia virus E26.

scientific article

Erythroblast cell lines transformed by a temperature-sensitive mutant of avian erythroblastosis virus: a model system to study erythroid differentiation in vitro.

scientific article published in January 1982

Evidence for the multiple oncogenic potential of cloned leukemia virus: in vitro and in vitro studies with avian erythroblastosis virus

scientific article

Evidence for the possible existence of two envelope antigenic determinants and corresponding cell receptors for avian tumor viruses

article

Excision of Ets by an inducible site-specific recombinase causes differentiation of Myb-Ets-transformed hematopoietic progenitors

scientific article published on July 1996

Expression of a chicken lysozyme recombinant gene is regulated by progesterone and dexamethasone after microinjection into oviduct cells

article

Expression of embryonic haemoglobin in tsAEV-transformed embryonic erythroid cells during temperature-induced differentiation

scientific article published in January 1982

Expression of virus specific morphological cell transformation induced in enucleated cells

scientific article published on November 1976

Expression patterns of c-myb and of v-myb induced myeloid-1 (mim-1) gene during the development of the chick embryo

scientific article published in January 1992

Fibroblast-derived induced pluripotent stem cells show no common retroviral vector insertions

scientific article

Forcing cells to change lineages

scientific article

GATA-1 interacts with the myeloid PU.1 transcription factor and represses PU.1-dependent transcription

scientific article

Genome structure of HBI, a variant of acute leukemia virus MC29 with unique oncogenic properties

scientific article published on May 1983

Goose-type lysozyme gene of the chicken: sequence, genomic organization and expression reveals major differences to chicken-type lysozyme gene

scientific article published in October 1991

HDAC7 is a repressor of myeloid genes whose downregulation is required for transdifferentiation of pre-B cells into macrophages.

scientific article

Hematopoietic cells transformed in vitro by REVT avian reticuloendotheliosis virus express characteristics of very immature lymphoid cells

scientific article published in December 1981

Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential.

scientific article published in November 2003

Heterogeneity of embryonic and adult stem cells

scientific article

Hi-TEC reprogramming for organ regeneration

scientific article published on 01 September 2014

Historical origins of transdifferentiation and reprogramming

scientific article

Hormone-dependent terminal differentiation in vitro of chicken erythroleukemia cells transformed by ts mutants of avian erythroblastosis virus

scientific article

How do retroviral oncogenes induce transformation in avian erythroid cells?

scientific article

Hoxb5, a Trojan horse to generate T cells.

scientific article

Identification and characterization of the avian erythroblastosis virus erbB gene product as a membrane glycoprotein

scientific article published in February 1983

Identification of genes differentially expressed in two types of v-myb-transformed avian myelomonocytic cells

scientific article

Identification of interventricular septum precursor cells in the mouse embryo

scientific article published on 16 September 2006

Immunology: Blood lines redrawn

scientific article published in Nature

In Vitro Transformation of Chicken Bone Marrow Cells with Avian Erythroblastosis Virus ⬇️

scientific article published on November 1, 1975

In vitro transformation with avian myelocytomatosis virus strain CMII: characterization of the virus and its target cells

scientific article

Increased inflammation in lysozyme M-deficient mice in response to Micrococcus luteus and its peptidoglycan

scientific journal article

Induced pluripotent stem cell-derived human platelets: one step closer to the clinic ⬇️

scientific article

Induced pluripotent stem cell–derived human platelets: one step closer to the clinic

scientific article published in January 2011

Induction of transplantation resistance to Rous sarcoma isograft by avian leukosis virus

scientific article published in November 1969

Influence of the v-Myb transactivation domain on the oncoprotein's transformation specificity

scientific article

Interferon inhibits establishment of fibroblast infection with avian retroviruses

scientific article published in January 1982

Isolation and characterization of four new temperature-sensitive mutants of avian erythroblastosis virus (AEV).

scientific article published in December 1982

Isolation of clonal strains of chicken embryo fibroblasts

scientific article published on 01 July 1977

Klf2 is an essential regulator of vascular hemodynamic forces in vivo

scientific article published in December 2006

Leukemia as a multistep process: studies with avian retroviruses containing two oncogenes

scientific article published on March 1988

Leukemogenesis: Small differences in Myb have large effects ⬇️

scientific article published on 01 May 1998

Lineage commitment of transformed haematopoietic progenitors is determined by the level of PKC activity.

scientific article

Lymphoid myeloid lineage specification

scientific article published on 01 August 2008

MafB deficiency causes defective respiratory rhythmogenesis and fatal central apnea at birth

scientific journal article

MafB is an inducer of monocytic differentiation

scientific article

MafB is an interaction partner and repressor of Ets-1 that inhibits erythroid differentiation

scientific article

MafB represses erythroid genes and differentiation through direct interaction with c-Ets-1.

scientific article published on April 1997

Making eosinophils through subtle shifts in transcription factor expression

scientific article

Mechanism of leukemogenesis and of target cell specificity by defective avian leukemia viruses: a hypothesis

scientific article published on January 1979

Mechanism of virus-induced leukemogenesis in an animal model system

scientific article

Mechanisms and implications of phosphoinositide 3-kinase delta in promoting neutrophil trafficking into inflamed tissue.

scientific article published on 29 January 2004

Mechanisms for the transformation of myeloid and erythroid cells by the nuclear oncogene V-myb

scientific article published on January 1, 1992

Musashi 2 in hematopoiesis

scientific article

Musashi 2 is a regulator of the HSC compartment identified by a retroviral insertion screen and knockout mice

scientific article

Mutant avian erythroblastosis virus with restricted target cell specificity

scientific article published on December 1979

Mutant of avian erythroblastosis virus defective for erythroblast transformation: deletion in the erb portion of p75 suggests function of the protein in leukemogenesis

scientific article

Mutants of avian myelocytomatosis virus with smaller gag gene-related proteins have an altered transforming ability

scientific article published in November 1980

Mutations in v-myb alter the differentiation of myelomonocytic cells transformed by the oncogene.

scientific article published in December 1990

Myb and NF-M: combinatorial activators of myeloid genes in heterologous cell types

scientific article published on May 1993

Myb: a transcriptional activator linking proliferation and differentiation in hematopoietic cells.

scientific article

Myeloblasts transformed by the avian acute leukemia virus E26 are hormone-dependent for growth and for the expression of a putative myb-containing protein, p135 E26.

scientific article published on January 1982

Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment

scientific article published in July 2002

NF-M (chicken C/EBP beta) induces eosinophilic differentiation and apoptosis in a hematopoietic progenitor cell line.

scientific article

Oncogenicity of non-transforming mutants of avian sarcoma viruses

scientific article

Oncornavirus-induced sarcoma formation obscured by rapid development of lethal leukemia

scientific article published on January 1977

OneD: increasing reproducibility of Hi-C Samples with abnormal karyotypes

PU.1 and C/EBPalpha/beta convert fibroblasts into macrophage-like cells

scholarly article

PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors

scientific article

PU.1 is not strictly required for B cell development and its absence induces a B-2 to B-1 cell switch

scientific article

Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling

scientific article published on 2 April 2010

Pre-B cell to macrophage transdifferentiation without significant promoter DNA methylation changes

scientific article published on 15 November 2011

Production and characterization of antisera specific for the erb-portion of p75, the presumptive transforming protein of avian erythroblastosis virus

scientific article published in May 1981

Properties of mouse leukemia viruses. XV. Electron microscopic studies on the organization of Friend leukemia virus and other mammalian C-type viruses

scientific article published on January 1978

Proposed structure for the DNA-binding domain of the Myb oncoprotein based on model building and mutational analysis

article

Protein synthesis in differentiating normal and leukemic erythroid cells

scientific article

Protein truncation is required for the activation of the c-myb proto-oncogene

scientific article published on August 1991

Purification and characterization of cMGF, a novel chicken myelomonocytic growth factor

scientific article published on December 1984

Quail embryo fibroblasts transformed by four v-myc-containing virus isolates show enhanced proliferation but are non tumorigenic ⬇️

scientific article published on January 1, 1983

Reciprocal activation of GATA-1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages

scientific article published in October 2007

Recovery of myc-specific sequences by a partially transformation-defective mutant of avian myelocytomatosis virus, MC29, correlates with the restoration of transforming activity

scientific article

Regulation of eosinophil-specific gene expression by a C/EBP-Ets complex and GATA-1.

scientific article

Rem-1, a putative direct target gene of the Myb-Ets fusion oncoprotein in haematopoietic progenitors, is a member of the recoverin family.

scientific article published on March 1995

Reprogramming of Committed Lymphoid Cells by Enforced Transcription Factor Expression

scientific article published on 01 January 2010

Reprogramming of committed T cell progenitors to macrophages and dendritic cells by C/EBP alpha and PU.1 transcription factors

scientific article published in November 2006

Reversibility of differentiation and proliferative capacity in avian myelomonocytic cells transformed by tsE26 leukemia virus.

scientific article

Role of the v-erbA and v-erbB oncogenes of avian erythroblastosis virus in erythroid cell transformation

scientific article published on August 1983

S13, a rapidly oncogenic replication-defective avian retrovirus

scientific article published on 01 August 1985

Single cell RNA-seq identifies the origins of heterogeneity in efficient cell transdifferentiation and reprogramming

scientific article published on 12 March 2019

Size differences among the high molecular weight RNA's of avian tumor viruses

scientific article published in January 1971

Stepwise reprogramming of B cells into macrophages

scientific article

Strain-specific antigen of the avian leukosis sarcoma virus group. I. Isolation and immunological characterization

scientific article published in March 1970

Structure and specific antigens of avian leukosis viruses

scientific article published on 01 January 1970

Structure of the chicken myelomonocytic growth factor gene and specific activation of its promoter in avian myelomonocytic cells by protein kinases

scientific article published on April 1992

Structure of the lysozyme gene and expression in the oviduct and macrophages

article

Studies of simian sarcoma and simian sarcoma-associated virus. II. Isolation of the major viral glycoprotein, properties of this component and its specific antiserum

scientific article published on October 1978

Studies on the reproductive and cell-converting abilities of avian sarcoma visuses

scientific article published on 01 February 1971

Suppression of HIV type 1 replication by a dominant-negative Ets-1 mutant

scientific article

Synthesis of the nuclear protein cyclin does not correlate directly with transformation in quail embryo fibroblasts

scientific article

Target cell specificity of defective avian leukemia viruses: hematopoietic target cells for a given virus type can be infected but not transformed by strains of a different type ⬇️

scientific article published on January 1, 1980

Target cells for transformation with avian leukosis viruses

scientific article published on January 1976

Temperature-sensitive changes in the structure of globin chromatin in lines of red cell precursors transformed by ts-AEV.

scientific article published in April 1982

Temperature-sensitive mutant of avian erythroblastosis virus suggests a block of differentiation as mechanism of leukaemogenesis

scientific article published on October 1978

Temperature-sensitive mutants of MH2 avian leukemia virus that map in the v-mil and the v-myc oncogene respectively

scientific article published on July 1986

Tet2 facilitates the derepression of myeloid target genes during CEBPα-induced transdifferentiation of pre-B cells

scientific article published on 13 September 2012

The cellular oncogenes c-myc, c-myb and c-erb are transcribed in defined types of avian hematopoietic cells

scientific article published on November 1983

The dicyclohexylcarbodiimide-binding protein of the mitochondrial ATPase complex from beef heart. Isolation and amino acid composition

scientific article published on October 1978

The eosinophil-specific cell surface antigen, EOS47, is a chicken homologue of the oncofetal antigen melanotransferrin

scientific article published on February 1996

The expression pattern of the mafB/kr gene in birds and mice reveals that the kreisler phenotype does not represent a null mutant.

scientific article published in July 1997

The nuclear oncogenes v-erbA and v-ets cooperate in the induction of avian erythroleukemia

scientific article published on March 1, 1992

The transforming activity of the chicken c-myc gene can be potentiated by mutations.

scientific article published in January 1987

The transforming gene of avian acute leukemia virus MC29.

scientific article published in January 1983

Three new types of viral oncogene of cellular origin specific for haematopoietic cell transformation ⬇️

scientific article published on October 11, 1979

Three new types of viral oncogenes in defective avian leukemia viruses. II. Biological, genetic, and immunochemical evidence

scientific article published in January 1980

Thrombomucin, a novel cell surface protein that defines thrombocytes and multipotent hematopoietic progenitors

scientific article

Tissue specific expression of Yrk kinase: implications for differentiation and inflammation

scientific article published on March 2000

Tissue-specific control of brain-enriched miR-7 biogenesis

scientific article published on January 2013

Transcription factor-induced enhancer modulations during cell fate conversions

scientific article published on 19 August 2013

Transcription factors orchestrate dynamic interplay between genome topology and gene regulation during cell reprogramming

scientific article published on 15 January 2018

Transcriptional activation during cell reprogramming correlates with the formation of 3D open chromatin hubs

scientific article published on 22 May 2020

Transformation of both erythroid and myeloid cells by E26, an avian leukemia virus that contains the myb gene

scientific article published in December 1982

Transformation parameters in chicken fibroblasts transformed by AEV and MC29 avian leukemia viruses

scientific article published on April 1978

Transformation parameters of chicken embryo fibroblasts infected with the ts34 mutant of avian erythroblastosis virus

scientific article published in January 1980

Transforming capacities and defectiveness of avian leukemia viruses OK10 and E 26.

scientific article published on December 1979

Transforming capacities of avian erythroblastosis virus mutants deleted in the erbA or erbB oncogenes

scientific article published in January 1983

Truncation of the human EGF receptor leads to differential transforming potentials in primary avian fibroblasts and erythroblasts.

scientific article published on October 1988

Ts mutants of E26 leukemia virus allow transformed myeloblasts, but not erythroblasts or fibroblasts, to differentiate at the nonpermissive temperature

scientific article published in December 1984

Tumor specificity of acute avian leukemia viruses reflected by their transformation target cell specificity in vitro

scientific article published on January 1977

Two types of target cells for transformation with avian myelocytomatosis virus

scientific article published in August 1973

Unmasking A.I.D.S

scientific article published on 01 January 1984

Very Rapid and Efficient Generation of Induced Pluripotent Stem Cells from Mouse Pre-B Cells

scientific article published in January 2016

Whsc1 links pluripotency exit with mesendoderm specification

scientific article published on 24 June 2019

Zrf1 is required to establish and maintain neural progenitor identity

scientific article published on January 2014

[Storage of polysaccharides in virus-induced renal epitheliomas]

scientific article published on 01 January 1981

src- and fps-containing avian sarcoma viruses transform chicken erythroid cells ⬇️

scientific article published on November 1, 1984

v-Myb of E26 leukemia virus up-regulates bcl-2 and suppresses apoptosis in myeloid cells

scientific article published in November 1996

v-erbA cooperates with sarcoma oncogenes in leukemic cell transformation

scientific article published in May 1986

v-mil induces autocrine growth and enhanced tumorigenicity in v-myc-transformed avian macrophages

scientific article published in May 1986

v-myb and v-ets transform chicken erythroid cells and cooperate both in trans and in cis to induce distinct differentiation phenotypes

scientific article published in March 1991

v-myb dominance over v-myc in doubly transformed chick myelomonocytic cells

scientific article

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