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List of works by Anette-Gabriele Ziegler

A Public Health Antibody Screening Indicates a Marked Increase of SARS-CoV-2 Exposure Rate in Children during the Second Wave

scientific article

A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function

scientific article published in September 2017

A high-throughput population screening system for the estimation of genetic risk for type 1 diabetes: an application for the TEDDY (the Environmental Determinants of Diabetes in the Young) study

scientific article published in October 2007

A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes

scientific article published in January 2018

A peripheral blood transcriptomic signature predicts autoantibody development in infants at risk of type 1 diabetes.

scientific article published on 8 March 2018

A strategy to find gene combinations that identify children who progress rapidly to type 1 diabetes after islet autoantibody seroconversion

scientific article published on 19 November 2013

A type I interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes.

scientific article

Advances in the prediction and natural history of type 1 diabetes

scientific article published on September 2010

Age, HLA, and Sex Define a Marked Risk of Organ-Specific Autoimmunity in First-Degree Relatives of Patients With Type 1 Diabetes

scientific article published on 18 June 2019

Ambient air pollution and early manifestation of type 1 diabetes.

scientific article

An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes

scientific article published on 09 June 2019

An interferon-induced helicase (IFIH1) gene polymorphism associates with different rates of progression from autoimmunity to type 1 diabetes ⬇️

scientific article

Analgesic antipyretic use among young children in the TEDDY study: no association with islet autoimmunity

scientific article

Association Between Early-Life Antibiotic Use and the Risk of Islet or Celiac Disease Autoimmunity

scientific article

Association of Dendritic Cell Signatures With Autoimmune Inflammation Revealed by Single-Cell Profiling

scientific article published on 06 April 2019

Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study.

scientific article

Association of Gluten Intake During the First 5 Years of Life With Incidence of Celiac Disease Autoimmunity and Celiac Disease Among Children at Increased Risk

scientific article published on 01 August 2019

Association of Infection in Early Life and Risk of Developing Type 1 Diabetes--Reply.

scientific article

Associations of growth patterns and islet autoimmunity in children with increased risk for type 1 diabetes: a functional analysis approach

scientific article published on 18 February 2016

Associations of maternal type 1 diabetes with childhood adiposity and metabolic health in the offspring: a prospective cohort study

article

Autoantibodies to N-terminally truncated GAD improve clinical phenotyping of individuals with adult-onset diabetes: Action LADA 12.

scientific article published on 4 April 2018

Autoantibody-negative insulin-dependent diabetes mellitus after SARS-CoV-2 infection: a case report

scientific article published on 02 September 2020

BMI at age 8 years is influenced by the type 2 diabetes susceptibility genes HHEX-IDE and CDKAL1

scientific article

Biomarker discovery study design for type 1 diabetes in The Environmental Determinants of Diabetes in the Young (TEDDY) study

scientific article published in July 2014

Blood draws up to 3% of blood volume in clinical trials are safe in children

scientific article published on 30 October 2018

Breastfeeding duration in families with type 1 diabetes compared to non-affected families: results from BABYDIAB and DONALD studies in Germany

scientific article published on 01 September 2008

C-reactive protein concentration is not related to islet autoimmunity status in offspring of parents with type 1 diabetes

scientific article published on 01 May 2005

CD4 T cell activation, function, and metabolism are inhibited by low concentrations of DMSO

scientific article published on 07 September 2018

Characterization of antibody responses to endogenous and exogenous antigen in the nonobese diabetic mouse

scientific article published in February 2003

Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease

scientific article

Circulating unmethylated CHTOP and INS DNA fragments provide evidence of possible islet cell death in youth with obesity and diabetes

scientific article published on 31 July 2020

Classification tree analyses reveal limited potential for early targeted prevention against childhood overweight.

scientific article

Concentration and activity of the soluble form of the interleukin-7 receptor α in type 1 diabetes identifies an interplay between hyperglycemia and immune function

scientific article published on March 2013

Costs of Public Health Screening of Children for Presymptomatic Type 1 Diabetes in Bavaria, Germany

scientific article published in 2022

Cytotoxicity-Related Gene Expression and Chromatin Accessibility Define a Subset of CD4+ T Cells That Mark Progression to Type 1 Diabetes

scientific article published on 01 March 2022

Distinct Growth Phases in Early Life Associated With the Risk of Type 1 Diabetes: The TEDDY Study

scientific article published on 02 January 2020

Does charge-free screening improve detection of gestational diabetes in women from deprived areas: a cross-sectional study

scientific article

Does diabetes appear in distinct phenotypes in young people? Results of the diabetes mellitus incidence Cohort Registry (DiMelli).

scientific article

Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes

scientific article

Early determinants of type 1 diabetes: experience from the BABYDIAB and BABYDIET studies ⬇️

scientific article published on 01 June 2011

Early infant growth is associated with the risk of islet autoimmunity in genetically susceptible children

scientific article published on 21 February 2014

Effect of a single autologous cord blood infusion on beta-cell and immune function in children with new onset type 1 diabetes: a non-randomized, controlled trial

scientific article

Elimination of dietary gluten does not reduce titers of type 1 diabetes-associated autoantibodies in high-risk subjects

scientific article published in July 2002

Erratum to: Feature ranking of type 1 diabetes susceptibility genes improves prediction of type 1 diabetes

article

Evaluating the diet of children at increased risk for type 1 diabetes: first results from the TEENDIAB study

scientific article published on 02 January 2014

Evidence for in vivo primed and expanded autoreactive T cells as a specific feature of patients with type 1 diabetes

scientific article published on 01 November 2007

Factors associated with longitudinal food record compliance in a paediatric cohort study.

scientific article

Fasting hypoglycemia is associated with disease progression in presymptomatic early stage type 1 diabetes

scientific article published on 03 September 2018

Feature ranking of type 1 diabetes susceptibility genes improves prediction of type 1 diabetes

scientific article published on 4 September 2014

Flexible Bayesian additive joint models with an application to type 1 diabetes research

scientific article published on 10 August 2017

GAD autoantibody affinity and epitope specificity identify distinct immunization profiles in children at risk for type 1 diabetes

scientific article published on 26 February 2007

GAD autoantibody affinity in adult patients with latent autoimmune diabetes, the study participants of a GAD65 vaccination trial

scientific article published on 5 March 2014

GAD autoantibody affinity in schoolchildren from the general population

scientific article published on 18 June 2014

GM-CSF producing autoreactive CD4+ T cells in type 1 diabetes

scientific article published on 8 December 2017

Genetic Contribution to the Divergence in Type 1 Diabetes Risk Between Children From the General Population and Children From Affected Families

scientific article published on 17 January 2019

Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children.

scientific article published on 3 April 2018

German new onset diabetes in the young incident cohort study: DiMelli study design and first-year results ⬇️

scientific article published on November 10, 2010

HHEX-IDE polymorphism is associated with low birth weight in offspring with a family history of type 1 diabetes

scientific article published on 21 July 2009

HLA-typing, clinical, and immunological characterization of youth with type 2 diabetes mellitus phenotype from the German/Austrian DPV database

scientific article published on 30 April 2013

Harmonization of glutamic acid decarboxylase and islet antigen-2 autoantibody assays for national institute of diabetes and digestive and kidney diseases consortia

scientific article

Hierarchical Order of Distinct Autoantibody Spreading and Progression to Type 1 Diabetes in the TEDDY Study

scientific article published on 08 July 2020

Human Breath Gas Analysis in the Screening of Gestational Diabetes Mellitus ⬇️

scientific article published on July 9, 2012

ISPAD Clinical Practice Consensus Guidelines 2018: Stages of type 1 diabetes in children and adolescents

scientific article published on 01 October 2018

Identification of infants with increased type 1 diabetes genetic risk for enrollment into Primary Prevention Trials-GPPAD-02 study design and first results

scientific article published on 13 June 2019

Incomplete immune response to coxsackie B viruses associates with early autoimmunity against insulin

scientific article published on 8 September 2016

Infections in Early Life and Development of Type 1 Diabetes

scientific article published on May 2016

Infections in early Life and development of celiac disease

scientific article published on 16 June 2017

Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

scientific article

Lack of association of type 2 diabetes susceptibility genotypes and body weight on the development of islet autoimmunity and type 1 diabetes

scientific article

Longitudinal Frequencies of Blood Leukocyte Subpopulations Differ between NOD and NOR Mice but Do Not Predict Diabetes in NOD Mice

scientific article published on 4 February 2016

Longitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study

scientific article published on 06 February 2020

Markedly reduced rate of diabetic ketoacidosis at onset of type 1 diabetes in relatives screened for islet autoantibodies

scientific article published on 08 November 2011

Maternal Dietary Supplement Use and Development of Islet Autoimmunity in the offspring: the TEDDY Study

article

Maternal Type 1 Diabetes Reduces Autoantigen-Responsive CD4+ T Cells in Offspring

scientific article published on 02 January 2020

Maternal use of dietary supplements during pregnancy is not associated with coeliac disease in the offspring: The Environmental Determinants of Diabetes in the Young (TEDDY) study

scientific article

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study.

scientific article published on 21 September 2017

Miscalculation and Errors in Numbers Reported in Table.

scientific article published on 21 November 2016

Neonatal and infant beta cell hormone concentrations in relation to type 1 diabetes risk

scientific article published on 19 February 2014

Novel minor HLA DR associated antigens in type 1 diabetes

scientific article published on 07 July 2018

Oral insulin immunotherapy in children at risk for type 1 diabetes in a randomised controlled trial

scientific article published on 30 January 2021

Oral insulin therapy for primary prevention of type 1 diabetes in infants with high genetic risk: the GPPAD-POInT (global platform for the prevention of autoimmune diabetes primary oral insulin trial) study protocol

scientific article published on 28 June 2019

Peptide serum markers in islet autoantibody-positive children

scientific article

Plasma ascorbic acid and the risk of islet autoimmunity and type 1 diabetes: the TEDDY study

scientific article published on 14 November 2019

Predicting Islet Cell Autoimmunity and Type 1 Diabetes: An 8-Year TEDDY Study Progress Report

scientific article published on 09 April 2019

Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children

scientific article published on 29 January 2019

Prediction of type 1 diabetes using a genetic risk model in the Diabetes Autoimmunity Study in the Young

scientific article published on 11 July 2017

Prevalence of vitamin D deficiency in pre-type 1 diabetes and its association with disease progression

scientific article published on 16 February 2014

Progression from single to multiple islet autoantibodies often occurs soon after seroconversion: implications for early screening

scientific article published on 20 November 2014

Prospective evaluation of risk factors for the development of islet autoimmunity and type 1 diabetes during puberty - TEENDIAB: study design ⬇️

scientific article published on March 29, 2011

Prospective virome analyses in young children at increased genetic risk for type 1 diabetes

scientific article published on 02 December 2019

Proteomic Landscape of Patient-Derived CD4+ T Cells in Recent-Onset Type 1 Diabetes.

scientific article published on 28 November 2017

Public health antibody screening indicates a six-fold higher SARS-CoV-2 exposure rate than reported cases in children

scientific article published on 29 October 2020

Randomized 52-week Phase 2 Trial of Albiglutide Versus Placebo in Adult Patients With Newly Diagnosed Type 1 Diabetes

scientific article published on 27 March 2020

Respiratory infections in early life and the development of islet autoimmunity in children at increased type 1 diabetes risk: evidence from the BABYDIET study.

scientific article published on September 2013

Role of Type 1 Diabetes-Associated SNPs on Risk of Autoantibody Positivity in the TEDDY Study

scientific article

Screening for Type 1 Diabetes Risk in Newborns: The Freder1k Pilot Study in Saxony

scientific article published on 9 November 2017

Searching peripheral blood mononuclear cells of children with viral respiratory tract infections preceding islet autoimmunity for viruses by high-throughput sequencing.

scientific article published on 23 April 2018

Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children

scientific article published on June 2013

Soluble IL-7 receptor alpha concentration in cord blood is linked to sex and maternal diabetes, but not with subsequent development of type 1 diabetes

scientific article published on 13 February 2020

Soluble interleukin-2 receptor alpha in preclinical type 1 diabetes

scientific article published on 05 September 2013

TEDDY--The Environmental Determinants of Diabetes in the Young: an observational clinical trial

scientific article published on 01 October 2006

Telomere length is not a main factor for the development of islet autoimmunity and type 1 diabetes in the TEDDY study

scientific article published on 16 March 2022

Temporal changes in gastrointestinal fungi and the risk of autoimmunity during early childhood: the TEDDY study

scientific article published on 01 January 2022

Temporal development of the gut microbiome in early childhood from the TEDDY study

scientific article published in Nature

Tetraspanin 7 autoantibodies in type 1 diabetes

scientific article published on 25 May 2016

The Authors Respond

scientific article published on 01 July 2016

The Environmental Determinants of Diabetes in the Young (TEDDY): genetic criteria and international diabetes risk screening of 421 000 infants

scientific article published on 12 May 2011

The human gut microbiome in early-onset type 1 diabetes from the TEDDY study

scientific article published in Nature

Thymus Growth and Fetal Immune Responses in Diabetic Pregnancies

scientific article published on 14 November 2017

Time-Resolved Autoantibody Profiling Facilitates Stratification of Preclinical Type 1 Diabetes in Children

article

Timing of gluten introduction and islet autoimmunity in young children: updated results from the BABYDIET study

scientific article published on 01 September 2014

Towards a functional hypothesis relating anti-islet cell autoimmunity to the dietary impact on microbial communities and butyrate production

scientific article

Transient Epstein-Barr virus reactivation in CD3 monoclonal antibody-treated patients

scientific article published on 09 December 2009

Translating mucosal antigen based prevention of autoimmune diabetes to human.

scientific article published in January 2008

Transmission of maternal islet antibodies and risk of autoimmune diabetes in offspring of mothers with type 1 diabetes

scientific article published on January 2004

Treatment of recent-onset type 1 diabetic patients with DiaPep277: results of a double-blind, placebo-controlled, randomized phase 3 trial

scientific article published in January 2014

Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice.

scientific article

Why is the presence of autoantibodies against GAD associated with a relatively slow progression to clinical diabetes?

scientific article published on 26 May 2020

Widespread seasonal gene expression reveals annual differences in human immunity and physiology

scientific article published on 12 May 2015

Yield of a Public Health Screening of Children for Islet Autoantibodies in Bavaria, Germany

scientific article published on 01 January 2020

miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes

scientific article published on 13 December 2019

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