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List of works by Stephan Becker

131 Replication and assembly of filoviruses.

scientific article published on 7 March 2014

A Fluorescently Labeled Marburg Virus Glycoprotein as a New Tool to Study Viral Transport and Assembly

scientific article published on 01 November 2018

A Highly Immunogenic and Protective Middle East Respiratory Syndrome Coronavirus Vaccine Based on a Recombinant Measles Virus Vaccine Platform.

scientific article

A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA

scientific article

A Polymorphism within the Internal Fusion Loop of the Ebola Virus Glycoprotein Modulates Host Cell Entry.

scientific article published on 22 February 2017

A Randomized, Blinded, Dose-Ranging Trial of an Ebola Virus Glycoprotein (EBOV GP) Nanoparticle Vaccine with Matrix-M™ Adjuvant in Healthy Adults

scientific article published on 11 October 2019

A Single Amino Acid Change in the Marburg Virus Matrix Protein VP40 Provides a Replicative Advantage in a Species-Specific Manner

scientific article published on 18 November 2015

A live-cell imaging system for visualizing the transport of Marburg virus nucleocapsid-like structures

scientific article published on 19 December 2019

Acute Ebola virus disease patient treatment and health-related quality of life in health care professionals: A controlled study

scientific article published on 24 September 2015

Adjuvant formulated virus-like particles expressing native-like forms of the Lassa virus envelope surface glycoprotein are immunogenic and induce antibodies with broadly neutralizing activity

scientific article published on 04 August 2020

An active site mutation increases the polymerase activity of the guinea pig-lethal Marburg virus

scientific article published on 22 July 2016

An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus

scientific article published on 11 July 2004

Analysis of Diagnostic Findings From the European Mobile Laboratory in Guéckédou, Guinea, March 2014 Through March 2015

scientific article published on 16 September 2016

Analysis of Ebola Virus Entry Into Macrophages

scientific article

Analysis of determinants in filovirus glycoproteins required for tetherin antagonism

scientific article published on 9 April 2014

Analysis of the interaction of Ebola virus glycoprotein with DC-SIGN (dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin) and its homologue DC-SIGNR.

scientific article published on November 2007

Analysis of the multifunctionality of Marburg virus VP40

scientific article published on 05 November 2018

Assembly of the Marburg virus envelope

scientific article published on 20 December 2012

Basolateral budding of Marburg virus: VP40 retargets viral glycoprotein GP to the basolateral surface

scientific article published on November 2007

Bile salt-induced apoptosis involves NADPH oxidase isoform activation

scientific journal article

Budding of Marburgvirus is associated with filopodia

scientific article published on 28 November 2006

CD95 tyrosine phosphorylation is required for CD95 oligomerization

scientific article published on 29 December 2006

Can falls be predicted with gait analytical and posturographic measurement systems? A prospective follow-up study in a nursing home population

scientific article published on July 27, 2012

Characterization of severe acute respiratory syndrome coronavirus membrane protein

scientific article published on 19 January 2006

Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors

scientific article published on 19 March 2019

Characterization of the Lassa virus matrix protein Z: electron microscopic study of virus-like particles and interaction with the nucleoprotein (NP).

scientific article published on March 2004

Cleavage of the Junin Virus Nucleoprotein Serves a Decoy Function To Inhibit the Induction of Apoptosis during Infection ⬇️

scientific article published on October 17, 2012

Complete Genome Sequence of an Ebola Virus Isolate Imported from Sierra Leone to Germany Determined by Circle Sequencing

scientific article published on 06 October 2016

Comprehensive Characterization of Cellular Immune Responses Following Ebola Virus Infection.

scientific article published on 31 October 2016

Control measures following a case of imported Lassa fever from Togo, North Rhine Westphalia, Germany, 2016.

scientific article published on September 2017

Corrigendum: Differential transcriptional responses to Ebola and Marburg virus infection in bat and human cells

scientific article

Cryo-electron tomography of Marburg virus particles and their morphogenesis within infected cells

scientific article published in November 2011

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors

scientific article from

Crystal structure of the C-terminal domain of Ebola virus VP30 reveals a role in transcription and nucleocapsid association

scientific article

DC-SIGN and DC-SIGNR interact with the glycoprotein of Marburg virus and the S protein of severe acute respiratory syndrome coronavirus

scientific article published on November 2004

Detectable Vesicular Stomatitis Virus (VSV)-Specific Humoral and Cellular Immune Responses Following VSV-Ebola Virus Vaccination in Humans

article

Development and characterization of an indirect ELISA to detect SARS-CoV - 2 spike protein-specific antibodies

scientific article published on 04 January 2021

Development of an antibody capture ELISA using inactivated Ebola Zaire Makona virus

scientific article published on 16 October 2015

Development of an immunofiltration-based antigen-detection assay for rapid diagnosis of Ebola virus infection

scientific article

Development, characterization and use of monoclonal VP40-antibodies for the detection of Ebola virus

scientific article published on July 2003

Diagnostic reverse-transcription polymerase chain reaction kit for filoviruses based on the strain collections of all European biosafety level 4 laboratories

scientific article

Differential transcriptional responses to Ebola and Marburg virus infection in bat and human cells

scientific article

Dose-dependent T-cell Dynamics and Cytokine Cascade Following rVSV-ZEBOV Immunization

scientific article

Dynamic Phosphorylation of VP30 Is Essential for Ebola Virus Life Cycle

scientific article

Dynamic phosphorylation of Ebola virus VP30 in NP-induced inclusion bodies

scientific article published on 12 September 2017

Ebola Virus Nucleocapsid-Like Structures Utilize Arp2/3 Signaling for Intracellular Long-Distance Transport

scientific article published on 19 July 2020

Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers

scientific article published on 05 October 2020

Ebola virus VP30-mediated transcription is regulated by RNA secondary structure formation

scientific article

Ebola virus enters host cells by macropinocytosis and clathrin-mediated endocytosis

scientific article

Ebola virus proteins NP, VP35, and VP24 are essential and sufficient to mediate nucleocapsid transport

scientific article published on 16 January 2018

Ebola virus transcription activator VP30 is a zinc-binding protein

scientific article

Ectodomain shedding of the glycoprotein GP of Ebola virus

scientific article published on 22 April 2004

Efficient budding of the tacaribe virus matrix protein z requires the nucleoprotein

scientific article published on 27 January 2010

Electron tomography reveals the steps in filovirus budding

scientific article

Endosomal Acidification and Activation of NADPH Oxidase Isoforms Are Upstream Events in Hyperosmolarity-induced Hepatocyte Apoptosis

scientific article published in Journal of Biological Chemistry

Epidemiological study to detect active SARS-CoV-2 infections and seropositive persons in a selected cohort of employees in the Frankfurt am Main metropolitan area

scientific article published on 25 May 2020

Epitopes of Naturally Acquired and Vaccine-induced Anti-Ebola Virus Glycoprotein Antibodies in Single Amino Acid Resolution

scientific article published on 28 May 2020

Establishment and application of an infectious virus-like particle system for Marburg virus

scientific article published on 13 January 2010

Establishment of fruit bat cells (Rousettus aegyptiacus) as a model system for the investigation of filoviral infection

scientific article

Exploring synergies between academia and vaccine manufacturers: a pilot study on how to rapidly produce vaccines to combat emerging pathogens

scientific article

External quality assessment study for ebolavirus PCR-diagnostic promotes international preparedness during the 2014 - 2016 Ebola outbreak in West Africa

scientific article

Favipiravir and Ribavirin Treatment of Epidemiologically Linked Cases of Lassa Fever

scientific article published on September 2017

Field Evaluation of Capillary Blood Samples as a Collection Specimen for the Rapid Diagnosis of Ebola Virus Infection During an Outbreak Emergency

scientific article

Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names

scientific article published on 26 September 2014

First international quality assurance study on the rapid detection of viral agents of bioterrorism

scientific article published on April 2004

Fluorescence resonance energy transfer analysis of proapoptotic CD95-EGF receptor interactions in Huh7 cells.

scientific article published on February 2005

From hybridomas to a robust microalgal-based production platform: molecular design of a diatom secreting monoclonal antibodies directed against the Marburg virus nucleoprotein

scientific article

Functional Characterization of Adaptive Mutations during the West African Ebola Virus Outbreak.

scientific article

Generation of therapeutic antisera for emerging viral infections

scientific article published on 05 October 2018

Genome Sequence of Lassa Virus Isolated from the First Domestically Acquired Case in Germany

scientific article published on 22 September 2016

Genus-specific recruitment of filovirus ribonucleoprotein complexes into budding particles

scientific article

Hemorrhagic Diathesis in Borrelia recurrentis Infection Imported to Germany

scientific article published on May 2016

Hexamer phasing governs transcription initiation in the 3'-leader of Ebola virus

scientific article published on 10 January 2020

High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus

scientific article published on 21 January 2015

Homo-oligomerization of Marburgvirus VP35 is essential for its function in replication and transcription

scientific article published on December 2005

Hospital hygiene - Influenza

scientific article

Human Cell Tropism and Innate Immune System Interactions of Human Respiratory Coronavirus EMC Compared to Those of Severe Acute Respiratory Syndrome Coronavirus ⬇️

scientific article published on February 28, 2013

Humoral and cellular immune response induced by rVSVΔG-ZEBOV-GP vaccine among frontline workers during the 2013-2016 West Africa Ebola outbreak in Guinea

scientific article published on 01 June 2020

Hydrophobic bile salts induce hepatocyte shrinkage via NADPH oxidase activation

scientific article

Hydrophobic bile salts trigger ceramide formation through endosomal acidification

scientific journal article

Hypoosmotic swelling and ammonia increase oxidative stress by NADPH oxidase in cultured astrocytes and vital brain slices

scientific article published on May 2007

In vitro evaluation of antisense RNA efficacy against filovirus infection, by use of reverse genetics

scientific article published on November 2007

Inclusion bodies are a site of ebolavirus replication

scientific article

Infection of naive target cells with virus-like particles: implications for the function of ebola virus VP24.

scientific article

Influenza virus budding from the tips of cellular microvilli in differentiated human airway epithelial cells ⬇️

scientific article published on January 3, 2013

Inhibition of Marburg virus protein expression and viral release by RNA interference

scientific article published on April 2005

Inhibition of filovirus replication by the zinc finger antiviral protein

scientific article published on 20 December 2006

Interaction with Tsg101 is necessary for the efficient transport and release of nucleocapsids in marburg virus-infected cells

scientific article (publication date: October 2014)

Intraobserver reliability of posturography in healthy subjects

scientific article

Intraobserver reliability of posturography in patients with vestibular neuritis ⬇️

scientific article published on August 16, 2013

Investigating the zoonotic origin of the West African Ebola epidemic

scientific article

Involvement of NADPH oxidase isoforms and Src family kinases in CD95-dependent hepatocyte apoptosis

scientific article

Involvement of the Src family kinase yes in bile salt-induced apoptosis

scientific article published in November 2004

LSECtin interacts with filovirus glycoproteins and the spike protein of SARS coronavirus

scientific article

Live-Cell Imaging of Filoviruses

scientific article published on January 2017

Live-cell imaging of Marburg virus-infected cells uncovers actin-dependent transport of nucleocapsids over long distances

scientific article

Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients

scientific article published on 13 July 2020

Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients

scientific article published on 01 September 2020

Longitudinal antibody and T cell responses in Ebola virus disease survivors and contacts: an observational cohort study

scientific article published on 13 October 2020

Management of Microbiological Samples in a Confirmed Case of Ebola Virus Disease: Constraints and Limitations.

scientific article

Management of accidental exposure to Ebola virus in the biosafety level 4 laboratory, Hamburg, Germany

scientific article published on November 2011

Marburg biosafety and biosecurity scale (MBBS): a framework for risk assessment and risk communication

scientific article published on 20 March 2015

Marburg virus inclusions: A virus-induced microcompartment and interface to multivesicular bodies and the late endosomal compartment

scientific article published on 30 May 2015

Marburg virus regulates the IRE1/XBP1-dependent unfolded protein response to ensure efficient viral replication

scientific article published on 01 January 2019

Measles virus M protein-driven particle production does not involve the endosomal sorting complex required for transport (ESCRT) system

scientific article

Middle East respiratory syndrome coronavirus spike protein delivered by modified vaccinia virus Ankara efficiently induces virus-neutralizing antibodies

scientific article published on 28 August 2013

Morphology of Marburg virus NP-RNA.

scientific article published on May 2002

Multi-level inhibition of coronavirus replication by chemical ER stress

scientific article published on 20 September 2021

Multivesicular bodies as a platform for formation of the Marburg virus envelope

scientific article published on November 2004

New Lineage of Lassa Virus, Togo, 2016

scientific article published in March 2018

Nipah Virus Matrix Protein Influences Fusogenicity and Is Essential for Particle Infectivity and Stability

scientific article published on 16 December 2015

Nucleic Acid-Sensing Toll-like Receptors Are Essential for the Control of Endogenous Retrovirus Viremia and ERV-Induced Tumors ⬇️

scientific article published on November 8, 2012

Nucleocapsid formation and RNA synthesis of Marburg virus is dependent on two coiled coil motifs in the nucleoprotein

scientific article

Oligomerization of Ebola virus VP30 is essential for viral transcription and can be inhibited by a synthetic peptide

scientific article published on 11 August 2003

Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe

scientific article

Phosphorylation of Ebola virus VP30 influences the composition of the viral nucleocapsid complex: impact on viral transcription and replication

scientific article

Phosphorylation of Marburg Virus NP Region II Modulates Viral RNA Synthesis ⬇️

scientific article published on November 1, 2011

Phosphorylation of Marburg virus matrix protein VP40 triggers assembly of nucleocapsids with the viral envelope at the plasma membrane ⬇️

scientific article published on November 10, 2011

Phosphorylation of VP30 impairs ebola virus transcription

scientific article published on 6 June 2002

Phylogeny of the SARS coronavirus

scientific article published in November 2003

Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV

scientific article published on 07 October 2019

Post-exposure prophylaxis with rVSV-ZEBOV following exposure to a patient with Ebola virus disease relapse in the UK: an operational, safety and immunogenicity report

scientific article published on 30 November 2019

Production of monoclonal antibodies and development of an antigen capture ELISA directed against the envelope glycoprotein GP of Ebola virus ⬇️

scientific article published on October 31, 2003

Profile and persistence of the virus-specific neutralizing humoral immune response in human survivors of Sudan ebolavirus (Gulu).

scientific article published on 12 April 2013

Profiling the native specific human humoral immune response to Sudan Ebola virus strain Gulu by chemiluminescence enzyme-linked immunosorbent assay.

scientific article

Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations

scientific article

Protective Efficacy of Recombinant Modified Vaccinia Virus Ankara Delivering Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein

scientific article published on 27 May 2015

RNA Binding of Ebola Virus VP30 Is Essential for Activating Viral Transcription

scientific article published on 8 June 2016

RNA binding specificity of Ebola virus transcription factor VP30

scientific article

RNA secondary structure at the transcription start site influences EBOV transcription initiation and replication in a length- and stability-dependent manner

scientific article published on 03 September 2020

Regulation of VP30-Dependent Transcription by RNA Sequence and Structure in the Genomic Ebola Virus Promoter

scientific article published on 02 December 2020

Risk communication and crisis communication in infectious disease outbreaks in Germany: what is being done, and what needs to be done

scientific article published on 7 May 2014

Role of Ebola virus VP30 in transcription reinitiation.

scientific article published on October 2008

Role of the transmembrane domain of marburg virus surface protein GP in assembly of the viral envelope

scientific article published on 31 January 2007

SARS vaccine protective in mice

scientific article published on August 2005

SARS--beginning to understand a new virus

scientific article published on December 2003

Safety and immunogenicity of a modified vaccinia virus Ankara vector vaccine candidate for Middle East respiratory syndrome: an open-label, phase 1 trial

scientific article published on 20 April 2020

Safety and immunogenicity of rVSVΔG-ZEBOV-GP Ebola vaccine in adults and children in Lambaréné, Gabon: A phase I randomised trial

scientific article published on 6 October 2017

Serine-Arginine Protein Kinase 1 Regulates Ebola Virus Transcription

scientific article published on 25 February 2020

Severe Ebola virus disease with vascular leakage and multiorgan failure: treatment of a patient in intensive care

scientific article published on 19 December 2014

Structural dissection of Ebola virus and its assembly determinants using cryo-electron tomography

scientific article

Structural insight into Marburg virus nucleoprotein-RNA complex formation

scientific article published on 04 March 2022

Structure and assembly of the Ebola virus nucleocapsid

scientific article published on 8 November 2017

Studies on membrane topology, N-glycosylation and functionality of SARS-CoV membrane protein

scientific article

Suramin is a potent inhibitor of Chikungunya and Ebola virus cell entry

scientific article published on 31 August 2016

Synthetic generation of influenza vaccine viruses for rapid response to pandemics

scientific article

Systems Vaccinology Identifies an Early Innate Immune Signature as a Correlate of Antibody Responses to the Ebola Vaccine rVSV-ZEBOV.

scientific article published on August 2017

TMPRSS2 and furin are both essential for proteolytic activation and spread of SARS-CoV-2 in human airway epithelial cells and provide promising drug targets

scientific article published on 16 April 2020

Tacaribe virus but not junin virus infection induces cytokine release from primary human monocytes and macrophages

scientific article

Temporal and spatial analysis of the 2014-2015 Ebola virus outbreak in West Africa

scientific article published on 17 June 2015

Tetherin inhibits Nipah virus but not Ebola virus replication in fruit bat cells

scientific article published on 17 January 2019

The Cytoplasmic Domain of Marburg Virus GP Modulates Early Steps of Viral Infection ⬇️

scientific article published on June 15, 2011

The Ebola Virus Nucleoprotein Recruits the Host PP2A-B56 Phosphatase to Activate Transcriptional Support Activity of VP30.

scientific article published on 27 December 2017

The Ebola virus glycoprotein contributes to but is not sufficient for virulence in vivo

scientific article published in 2012

The Importance of the NP: VP35 Ratio in Ebola Virus Nucleocapsid Formation ⬇️

scientific article published on November 1, 2011

The Marburg virus surface protein GP is phosphorylated at its ectodomain

scientific article published in March 2002

The New World arenavirus Tacaribe virus induces caspase-dependent apoptosis in infected cells.

scientific article published on 14 January 2016

The Src family kinase Yes triggers hyperosmotic activation of the epidermal growth factor receptor and CD95.

scientific article published on 23 March 2004

The clinically approved drugs amiodarone, dronedarone and verapamil inhibit filovirus cell entry

scientific article

The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised double-blind, placebo-controlled phase 1/2 trial

scientific article published on 3 August 2015

The integrity of the YxxL motif of Ebola virus VP24 is important for the transport of nucleocapsid-like structures and for the regulation of viral RNA synthesis

scientific article published on 26 February 2020

The matrix protein VP40 from Ebola virus octamerizes into pore-like structures with specific RNA binding properties

scientific article (publication date: April 2003)

The matrix protein of Marburg virus is transported to the plasma membrane along cellular membranes: exploiting the retrograde late endosomal pathway

scientific article published on March 2004

The molecular tweezer CLR01 inhibits Ebola and Zika virus infection

scientific article published on 8 February 2018

The natural compound silvestrol is a potent inhibitor of Ebola virus replication

scientific article

Transport of Ebolavirus Nucleocapsids Is Dependent on Actin Polymerization: Live-Cell Imaging Analysis of Ebolavirus-Infected Cells

scientific article published on 2 June 2015

Tsg101 is recruited by a late domain of the nucleocapsid protein to support budding of Marburg virus-like particles

scientific article

VACCINES. Ebola virus vaccines--preparing for the unexpected

scientific article

VP24 of Marburg virus influences formation of infectious particles

scientific article published on November 2005

VP40 octamers are essential for Ebola virus replication.

scientific article

VP40, the matrix protein of Marburg virus, is associated with membranes of the late endosomal compartment

scientific article published on February 2002

Vacuolar protein sorting pathway contributes to the release of Marburg virus

scientific article

Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses

scientific article

Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA

scientific article published on 5 November 2013

Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae

scientific article published on 29 January 2013

Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae

scientific article published on 23 September 2012

[Four years after the Ebola crisis : Challenges, experiences, and implications in the German public health context]

scientific article published on 01 September 2019

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