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List of works by Igor Jurišica

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

A 4-gene signature from histologically normal surgical margins predicts local recurrence in patients with oral carcinoma: clinical validation

scientific article published on 03 February 2020

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

scientific article published on 21 December 2016

A Proteome Resource of Ovarian Cancer Ascites: Integrated Proteomic and Bioinformatic Analyses To Identify Putative Biomarkers

A comprehensive catalogue of functional genetic variations in the EGFR pathway: protein-protein interaction analysis reveals novel genes and polymorphisms important for cancer research

scientific article published in September 2009

A gene signature in histologically normal surgical margins is predictive of oral carcinoma recurrence

scientific article

A stemness screen reveals C3orf54/INKA1 as a promoter of human leukemia stem cell latency

scientific article published on 22 February 2019

A tree-based approach for motif discovery and sequence classification.

scientific article published on 17 June 2011

Abstract 5073: Proteomic profiling of head and neck squamous cell carcinoma cell lines

Abstract B04: In vivo BioID identifies novel Myc interacting partners

Advances in ovarian cancer proteomics: the quest for biomarkers and improved therapeutic interventions.

scientific article published on August 2008

Algorithms for systematic identification of small subgraphs

scientific article published on January 2012

Allelic loss of the loci containing the androgen synthesis gene, StAR, is prognostic for relapse in intermediate-risk prostate cancer

scientific article published on 27 December 2011

An Integrated Approach Identifies Mediators of Local Recurrence in Head and Neck Squamous Carcinoma.

scientific article published on 7 February 2017

Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity

scientific article published on 09 March 2022

BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors

scientific article

CHIP-MYTH: a novel interactive proteomics method for the assessment of agonist-dependent interactions of the human β₂-adrenergic receptor

scientific article published on 19 February 2014

CUL7 is a novel antiapoptotic oncogene

scientific article

Cancer informatics in the post genomic era. Toward information-based medicine

scientific article published on January 2007

Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set

scientific article published in Nature Communications

Case-based reasoning in IVF: prediction and knowledge mining

scientific article published on January 1, 1998

Characterization of the apoptotic response of human leukemia cells to organosulfur compounds

scientific article

Circulating plant miRNAs can regulate human gene expression in vitro

scientific article published on 08 September 2016

Citrobacter rodentium alters the mouse colonic miRNome.

scientific article

Clinical Utility of Patient-Derived Xenografts to Determine Biomarkers of Prognosis and Map Resistance Pathways in EGFR-Mutant Lung Adenocarcinoma.

scientific article

Comparative systems biology of human and mouse as a tool to guide the modeling of human placental pathology

scientific article published on 16 June 2009

Comprehensive MicroRNA profiling for head and neck squamous cell carcinomas

scientific article

Copy number alterations of c-MYC and PTEN are prognostic factors for relapse after prostate cancer radiotherapy

article

CpG Island microarray probe sequences derived from a physical library are representative of CpG Islands annotated on the human genome

scientific article

Current applications of microarrays in head and neck cancer research

scientific article published on February 2004

Determinants of sensitivity to lovastatin-induced apoptosis in multiple myeloma

scientific article published on 01 June 2007

Developmental transcription factor NFIB is a putative target of oncofetal miRNAs and is associated with tumour aggressiveness in lung adenocarcinoma

scientific article published on 30 June 2016

Differential roles of cyclin D1 and D3 in pancreatic ductal adenocarcinoma

scientific article

Differentially expressed microRNAs in lung adenocarcinoma invert effects of copy number aberrations of prognostic genes.

scientific article published on 8 January 2018

Drugst.One — a plug-and-play solution for online systems medicine and network-based drug repurposing

scientific article published in 2024

Dysregulation of the mevalonate pathway promotes transformation

scientific article

Epithelial tumor suppressor ELF3 is a lineage-specific amplified oncogene in lung adenocarcinoma

scientific article published on 28 November 2019

Erratum: Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues

scholarly article published in Laboratory Investigation

Exploiting the mevalonate pathway to distinguish statin-sensitive multiple myeloma

scientific article published on April 2010

Exploiting the noise: improving biomarkers with ensembles of data analysis methodologies

scientific article

Extracellular Matrix Injury of Kidney Allografts in Antibody-Mediated Rejection: A Proteomics Study

scientific article published on 08 September 2020

Failed immune responses across multiple pathologies share pan-tumor and circulating lymphocytic targets

scientific article published on 26 March 2019

Fibrillin-1 (FBN-1) a new marker of germ cell neoplasia in situ

scientific article

Fundamentals of protein interaction network mapping

scientific article

GSOAP: A tool for visualisation of gene set over-representation analysis

scientific article published on 24 January 2020

Gene expression profiling in cervical cancer: an exploration of intratumor heterogeneity

scientific article published on October 2006

Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study

scientific article

Genomic amplicons target vesicle recycling in breast cancer

scientific article published on 20 July 2009

Genomic markers for malignant progression in pulmonary adenocarcinoma with bronchioloalveolar features

scientific article

Germline Mutation in MUS81 Resulting in Impaired Protein Stability is Associated with Familial Breast and Thyroid Cancer

scientific article published on 20 May 2020

HABP2 p.G534E variant in patients with family history of thyroid and breast cancer

scientific article published on 29 March 2017

High-throughput mapping of a dynamic signaling network in mammalian cells

scientific article (publication date: 11 March 2005)

IID 2018 update: context-specific physical protein-protein interactions in human, model organisms and domesticated species

scientific article published on 01 January 2019

Identification of a microRNA signature associated with progression of leukoplakia to oral carcinoma

scientific article published on 15 December 2009

Identification of microRNA-181a-5p and microRNA-4454 as mediators of facet cartilage degeneration

scientific article published on 04 August 2016

Identification of pathways associated with invasive behavior by ovarian cancer cells using multidimensional protein identification technology (MudPIT).

scientific article

Identification of synovial fluid microRNA signature in knee osteoarthritis: differentiating early- and late-stage knee osteoarthritis

scientific article published on 30 April 2016

Identifying Myc interactors

scientific article published in January 2013

Immune-enrichment of non-small cell lung cancer baseline biopsies for multiplex profiling define prognostic immune checkpoint combinations for patient stratification

scientific article published on 28 March 2019

Impaired tRNA nuclear export links DNA damage and cell-cycle checkpoint

scientific article

In silico drug screen in mouse liver identifies candidate calorie restriction mimetics

scientific article published on April 2012

In silico prediction of physical protein interactions and characterization of interactome orphans

scientific article

In-depth proteomics of ovarian cancer ascites: combining shotgun proteomics and selected reaction monitoring mass spectrometry.

scientific article

Inferring the functions of longevity genes with modular subnetwork biomarkers of Caenorhabditis elegans aging

scientific article published on 3 February 2010

Information fusion as an integrative cross-cutting enabler to achieve robust, explainable, and trustworthy medical artificial intelligence

scientific article published in 2022

Informed Use of Protein-Protein Interaction Data: A Focus on the Integrated Interactions Database (IID)

scientific article published on 01 January 2020

Inhibition of the sodium/potassium ATPase impairs N-glycan expression and function

scientific article

Integrated interactions database: tissue-specific view of the human and model organism interactomes

scientific article

Integrated proteomic and transcriptomic profiling of mouse lung development and Nmyc target genes

scientific article published on 08 May 2007

Integrating RAS status into prognostic signatures for adenocarcinomas of the lung

scientific article published on 21 January 2015

Integrative computational biology for cancer research

scientific article (publication date: October 2011)

Integrative transcriptome analysis identifies deregulated microRNA-transcription factor networks in lung adenocarcinoma.

scientific article published on 12 April 2016

Integrin alpha 11 regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells

scientific article

Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment

scientific article published in July 2011

L1 cell adhesion molecule promotes tumorigenicity and metastatic potential in non-small cell lung cancer

scientific article published on 3 February 2012

Large-scale discovery of previously undetected microRNAs specific to human liver.

scientific article

Loss of coordinated androgen regulation in nonmalignant ovarian epithelial cells with BRCA1/2 mutations and ovarian cancer cells

scientific article published on May 15, 2003

Lung cancer: developmental networks gone awry?

scientific article

MYC interaction with the tumor suppressive SWI/SNF complex member INI1 regulates transcription and cellular transformation

scientific article published on 07 June 2016

Making sense of lung-cancer gene-expression profiles

scientific article

MicroRNA signature obtained from the comparison of aggressive with indolent non-Hodgkin lymphomas: potential prognostic value in mantle-cell lymphoma

scientific article published on 8 July 2013

Modeling of lung cancer by an orthotopically growing H460SM variant cell line reveals novel candidate genes for systemic metastasis

scientific article published on August 2004

Modeling tumor progression via the comparison of stage-specific graphs.

scientific article

Molecular classification of oral cancer by cDNA microarrays identifies overexpressed genes correlated with nodal metastasis

scientific article published on July 2004

Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors

scientific article published on 17 October 2016

Molecular profiling of non-small cell lung cancer and correlation with disease-free survival

scientific article published on 01 June 2002

Multiple dysregulated pathways in nasopharyngeal carcinoma revealed by gene expression profiling

scientific article published in November 2006

Myc and its interactors take shape.

scientific article

NAViGaTing the micronome--using multiple microRNA prediction databases to identify signalling pathway-associated microRNAs

scientific article

NBN gain is predictive for adverse outcome following image-guided radiotherapy for localized prostate cancer

scientific article

NKX3.1 haploinsufficiency is prognostic for prostate cancer relapse following surgery or image-guided radiotherapy

scientific article published on 2 November 2011

NetwoRx: connecting drugs to networks and phenotypes in Saccharomyces cerevisiae

scientific article

Network-based characterization of drug-regulated genes, drug targets, and toxicity

scientific article published on June 27, 2012

Novel semantic similarity measure improves an integrative approach to predicting gene functional associations

scientific article published on 14 March 2013

Online predicted human interaction database

scientific article

Optimization and analysis of a quantitative real-time PCR-based technique to determine microRNA expression in formalin-fixed paraffin-embedded samples

scientific article published on 23 June 2010

Optimization of experimental design parameters for high-throughput chromatin immunoprecipitation studies

scientific article published on 21 October 2008

Optimized application of penalized regression methods to diverse genomic data

scientific article

Phenotypic and transcriptional plasticity directed by a yeast mitogen-activated protein kinase network.

scientific article

Physiological Tau Interactome in Brain and Its Link to Tauopathies

scientific article published on 07 May 2020

Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo

scientific article published on 22 February 2017

Potential role of CC chemokine receptor 6 in prediction of late-onset cytomegalovirus infection following solid organ transplant

scientific article published on 22 April 2015

Prediction of Protein-Protein Interactions.

scientific article published on 8 December 2017

Primary tumor xenografts of human lung adeno and squamous cell carcinoma express distinct proteomic signatures.

scientific article

Prioritizing therapeutics for lung cancer: an integrative meta-analysis of cancer gene signatures and chemogenomic data

scientific article (publication date: March 2015)

Prognostic and predictive gene signature for adjuvant chemotherapy in resected non-small-cell lung cancer

scientific article

Prognostic gene expression signature for squamous cell carcinoma of lung

scientific article published on 25 August 2010

Prognostic gene signatures for non-small-cell lung cancer

scientific article

Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer

scientific article

Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma

scientific article published on 10 September 2010

Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma

scientific article

Protein complex prediction with RNSC.

scientific article published in January 2012

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons

scientific journal article

Proteomics and Bioinformatics in Biomedical Research

scientific article published on 01 January 2006

Publisher Correction: Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set

scientific article published on 04 March 2019

Quantification of angiotensin II-regulated proteins in urine of patients with polycystic and other chronic kidney diseases by selected reaction monitoring.

scientific article published on 05 August 2016

RNAi screen identifies essential regulators of human brain metastasis-initiating cells.

scientific article published in August 2017

Re: Gene expression-based prognostic signatures in lung cancer: ready for clinical use?

scientific article

Recurrent genomic alterations in sequential progressive leukoplakia and oral cancer: drivers of oral tumorigenesis?

scientific article published on 08 January 2014

Reduced BRCA1 transcript levels in freshly isolated blood leukocytes from BRCA1 mutation carriers is mutation specific

scientific article published on 17 August 2016

Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6

scientific article

Retraction: Circulating plant miRNAs can regulate human gene expression in vitro

scientific article published on 22 May 2017

Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues

scientific article

Robust quantitative scratch assay

scientific article published on 31 December 2015

Role of Pirh2 in mediating the regulation of p53 and c-Myc

scientific article

SCRIPDB: a portal for easy access to syntheses, chemicals and reactions in patents

scientific article published on November 8, 2011

Severe COVID-19 Shares a Common Neutrophil Activation Signature with Other Acute Inflammatory States

scientific article published in March 2022

Sportomics suggests that albuminuria is a sensitive biomarker of hydration in cross combat

scientific article published in 2022

Stability and heterogeneity of expression profiles in lung cancer specimens harvested following surgical resection

scientific article

Stem cell gene expression programs influence clinical outcome in human leukemia.

scientific article published on 28 August 2011

Systematic Identification of Oncogenic EGFR Interaction Partners

scientific article published on 9 December 2016

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening

scientific article

Systematic protein-protein interaction mapping for clinically relevant human GPCRs

scientific article published on 15 March 2017

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

scientific article published on 19 September 2008

TP53 mutations in high grade serous ovarian cancer and impact on clinical outcomes: a comparison of next generation sequencing and bioinformatics analyses

scientific article published on 18 January 2019

The IMEx Coronavirus interactome: an evolving map of Coronaviridae-Host molecular interactions

scientific article published on 16 June 2020

The ablation of the matricellular protein EMILIN2 causes defective vascularization due to impaired EGFR-dependent IL-8 production affecting tumor growth.

scientific article published on 27 February 2018

The c-Myc oncogene directly induces the H19 noncoding RNA by allele-specific binding to potentiate tumorigenesis

scientific article (publication date: 15 May 2006)

The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells

scientific article

The murine caecal microRNA signature depends on the presence of the endogenous microbiota

scientific article published on 19 December 2011

The network interplay of interferon and Toll-like receptor signaling pathways in the anti-Candida immune response

scientific article published on 13 October 2021

Three-Gene Prognostic Classifier for Early-Stage Non–Small-Cell Lung Cancer

article

Tumor cell endogenous HIF-1α activity induces aberrant angiogenesis and interacts with TRAF6 pathway required for colorectal cancer development

scientific article published on 23 October 2020

Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study

scientific article

Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis

Understanding biology through intelligent systems

scientific article

Understanding prognostic gene expression signatures in lung cancer.

scientific article published on September 2009

Unequal evolutionary conservation of human protein interactions in interologous networks

scientific article published in 2007

Uninterrupted Sedentary Behavior Downregulates BRCA1 Gene Expression

scientific article published on 2 November 2015

Validating the prognostic value of marker genes derived from a non-small cell lung cancer microarray study.

scientific article published in November 2004

Validation of a histology-independent prognostic gene signature for early-stage, non-small-cell lung cancer including stage IA patients

scientific article published in January 2014

Why imaging data alone is not enough: AI-based integration of imaging, omics, and clinical data

scientific article published on 15 June 2019

mRNA transcript quantification in archival samples using multiplexed, color-coded probes

scientific article published on 9 May 2011

mirDIP 4.1-integrative database of human microRNA target predictions.

scientific article published on 29 November 2017

pathDIP 4: an extended pathway annotations and enrichment analysis resource for human, model organisms and domesticated species

scientific article published on 01 January 2020

pathDIP: an annotated resource for known and predicted human gene-pathway associations and pathway enrichment analysis.

scientific article published on 28 November 2016