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List of works by Michael Hengartner

A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs

scientific article

A conserved role for SNX9-family members in the regulation of phagosome maturation during engulfment of apoptotic cells

scientific article

A dynamic physical model of cell migration, differentiation and apoptosis in Caenorhabditis elegans

scientific article published on January 2012

A lectin-mediated resistance of higher fungi against predators and parasites.

scientific article published on 12 April 2011

A novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformation

scientific journal article

A pathway for phagosome maturation during engulfment of apoptotic cells

scientific article

A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans

scientific article

A worm rich in protein: Quantitative, differential, and global proteomics in Caenorhabditis elegans

scientific article published on 14 April 2010

Activation of C. elegans cell death protein CED-9 by an amino-acid substitution in a domain conserved in Bcl-2.

scientific article published on May 1994

Advances in apoptosis research ⬇️

scientific article published on November 25, 1997

Alteration of the nuclear pore complex in Ca(2+)-mediated cell death.

scientific article published in January 2010

Aminophospholipid translocase TAT-1 promotes phosphatidylserine exposure during C. elegans apoptosis.

scientific article published in June 2007

Analysis of C. elegans intestinal gene expression and polyadenylation by fluorescence-activated nuclei sorting and 3'-end-seq

scientific article

Apoptosis CED-4 is a stranger no more ⬇️

scientific article published on August 21, 1997

Apoptosis and the shape of death

article by Michael Otmar Hengartner published 1997 in Genesis

Apoptotic cell death under hypoxia.

scientific article published on May 2014

Biotoxicity assays for fruiting body lectins and other cytoplasmic proteins

scientific article published on January 2010

C. elegans GLA-3 is a novel component of the MAP kinase MPK-1 signaling pathway required for germ cell survival

scientific article

C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein

scientific journal article

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

scientific article

Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation

scientific article published on 25 July 2004

Caenorhabditis elegans DNA mismatch repair gene msh-2 is required for microsatellite stability and maintenance of genome integrity

scientific article

Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis

scientific article published in November 2002

Caenorhabditis elegans N-glycan Core β-galactoside Confers Sensitivity towards Nematotoxic Fungal Galectin CGL2

scientific article

Caenorhabditis elegans contains two distinct acid sphingomyelinases.

scientific article published in June 1998

Caenorhabditis elegans gene ced-9 protects cells from programmed cell death

scientific article published on April 9, 1992

Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans.

scientific article published in June 1998

Cell biology. Tickling macrophages, a serious business

scientific article

Cell biology: divide and conquer

scientific article

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

scientific article

Cleaning up the mess: cell corpse clearance in Caenorhabditis elegans

scientific article published on December 2012

Comparative analysis reveals conserved protein phosphorylation networks implicated in multiple diseases

scientific article published on 28 July 2009

Comparative functional analysis of the Caenorhabditis elegans and Drosophila melanogaster proteomes

scientific article

Correction: Long-term C. elegans immobilization enables high resolution developmental studies in vivo

scientific article published on 01 June 2018

Death and more: DNA damage response pathways in the nematode C. elegans.

scientific article published on January 2004

Death cycle and Swiss army knives ⬇️

scientific article published on January 29, 1998

Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents

scientific article

Deleted in cancer 1 (DICE1) is an essential protein controlling the topology of the inner mitochondrial membrane in C. elegans

scientific article published on 16 August 2006

Developmental apoptosis in C. elegans: a complex CEDnario

scientific article

Differential regulation of DNA damage response activation between somatic and germline cells in Caenorhabditis elegans.

scientific article

Differential regulation of germ line apoptosis and germ cell differentiation by CPEB family members in C. elegans

scientific article published on 31 July 2017

Dimerization of the fungal defense lectin CCL2 is essential for its toxicity against nematodes.

scientific article

Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration

scientific article (publication date: 13 February 2004)

Dying to hold you

scientific article published in Nature

Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans

scientific article published in Nature

Epigenetic regulation of histone H3 serine 10 phosphorylation status by HCF-1 proteins in C. elegans and mammalian cells

scientific article (publication date: 2007)

Erratum: A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans

scholarly article published in Nature Methods

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

scientific article

Establishing a Blueprint for CED-3-dependent Killing through Identification of Multiple Substrates for This Protease

scientific article published in Journal of Biological Chemistry

Finding function in novel targets: C. elegans as a model organism

scientific article published in May 2006

Functional identification of optimized RNAi triggers using a massively parallel sensor assay

scientific article

Generic comparison of protein inference engines

scientific article published on 4 November 2011

Genetic control of programmed cell death and aging in the nematode Caenorhabditis elegans.

scientific article published on July 1997

Genetics of apoptosis

scientific article published on January 1997

Genome-wide RNAi identifies p53-dependent and -independent regulators of germ cell apoptosis in C. elegans

scientific article published on 01 November 2004

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes.

scientific article published on 17 April 2009

HIF-1 antagonizes p53-mediated apoptosis through a secreted neuronal tyrosinase

scientific article published in June 2010

How the worm removes corpses: the nematode C. elegans as a model system to study engulfment.

scientific article

Identification of two signaling submodules within the CrkII/ELMO/Dock180 pathway regulating engulfment of apoptotic cells.

scientific article

LEM-3 - A LEM domain containing nuclease involved in the DNA damage response in C. elegans

scientific article (publication date: 2012)

Long-term C. elegans immobilization enables high resolution developmental studies in vivo.

scientific article published on 13 April 2018

Loss of Acetylcholine Signaling Reduces Cell Clearance Deficiencies in Caenorhabditis elegans

scientific article (publication date: 2016)

Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegans

scientific article

MINA-1 and WAGO-4 are part of regulatory network coordinating germ cell death and RNAi in C. elegans

scientific article published on 06 February 2019

Methylated glycans as conserved targets of animal and fungal innate defense.

scientific article

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

scientific article

Mitochondria as a Target of Environmental Toxicants ⬇️

scientific article published on April 29, 2013

Model organisms proteomics--from holobionts to human nutrition.

scientific article

Modeling the binding specificity of the RNA-binding protein GLD-1 suggests a function of coding region-located sites in translational repression

scientific article published on 23 August 2013

Molecular basis for galactosylation of core fucose residues in invertebrates: identification of caenorhabditis elegans N-glycan core alpha1,6-fucoside beta1,4-galactosyltransferase GALT-1 as a member of a novel glycosyltransferase family

scientific article published on 26 October 2009

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

scientific article (publication date: 2012)

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

scientific article

NER and HR pathways act sequentially to promote UV-C-induced germ cell apoptosis in Caenorhabditis elegans ⬇️

scientific article published on December 10, 2010

Natural Genetic Variation Differentially Affects the Proteome and Transcriptome in Caenorhabditis elegans.

scientific article published on 4 March 2016

Natural Genetic Variation Influences Protein Abundances in C. elegans Developmental Signalling Pathways.

scientific article

Nematotoxicity of Marasmius oreades agglutinin (MOA) depends on glycolipid binding and cysteine protease activity.

scientific article

No death without life: vital functions of apoptotic effectors

scientific article

Nonapoptotic Role for Apaf-1 in the DNA Damage Checkpoint

Nonapoptotic role for Apaf-1 in the DNA damage checkpoint

scientific article published on November 2007

PH domain of ELMO functions in trans to regulate Rac activation via Dock180

scientific article

PaxDb, a database of protein abundance averages across all three domains of life

scientific article

Phagocytosis of apoptotic cells is regulated by a UNC-73/TRIO-MIG-2/RhoG signaling module and armadillo repeats of CED-12/ELMO

scientific article

Plasticity of the β-Trefoil Protein Fold in the Recognition and Control of Invertebrate Predators and Parasites by a Fungal Defence System

scientific article

Post-transcriptional control of executioner caspases by RNA-binding proteins

scientific article published on October 2016

Predictive Modelling of Stem Cell Differentiation and Apoptosis in C. elegans

Programmed cell death in Caenorhabditis elegans

article

Programmed cell death in invertebrates.

scientific article published on February 1996

Programmed cell death. A rich harvest.

scientific article published in October 1994

Programmed cell death: alive and well in the new millennium ⬇️

scientific article published on December 1, 2001

Programmed cell death: from development to disease

article

Protection of C. elegans from anoxia by HYL-2 ceramide synthase

scientific article published in April 2009

Protein identification false discovery rates for very large proteomics data sets generated by tandem mass spectrometry

scientific article

RIP-chip-SRM--a new combinatorial large-scale approach identifies a set of translationally regulated bantam/miR-58 targets in C. elegans

scientific article

Rearrangements of the nucleosome structure in chromatin by poly(ADP-ribose)

scientific article published on 01 June 1992

Regulation of nicotinic receptor trafficking by the transmembrane Golgi protein UNC-50.

scientific article

Ribosome synthesis and MAPK activity modulate ionizing radiation-induced germ cell apoptosis in Caenorhabditis elegans

scientific article

Shotgun proteomics data from multiple organisms reveals remarkable quantitative conservation of the eukaryotic core proteome

scientific article

Small GTPase CDC-42 promotes apoptotic cell corpse clearance in response to PAT-2 and CED-1 in C. elegans

scientific article

Sugar antennae for guidance signals: syndecans and glypicans integrate directional cues for navigating neurons.

scientific article published on 25 August 2006

Syndecan regulates cell migration and axon guidance in C. elegans

scientific article published on 21 September 2005

Tales of cannibalism, suicide, and murder: Programmed cell death in C. elegans

scientific article

The HUPO initiative on Model Organism Proteomes, iMOP.

scientific article published in February 2012

The Wnt pathway controls cell death engulfment, spindle orientation, and migration through CED-10/Rac

scientific article

The biochemistry of apoptosis

scientific article (publication date: 12 October 2000)

The future of model organisms in human disease research

scientific article published on 18 July 2011

The genes pme-1 and pme-2 encode two poly(ADP-ribose) polymerases in Caenorhabditis elegans

scientific article published on November 2002

The genetics of programmed cell death in the nematode Caenorhabditis elegans.

scientific article

The initiative on Model Organism Proteomes (iMOP) Session September 6, 2011, Geneva, Switzerland

scientific article published in February 2012

The phosphoinositide phosphatase MTM-1 regulates apoptotic cell corpse clearance through CED-5-CED-12 in C. elegans.

scientific article published on 13 April 2011

The short coiled-coil domain-containing protein UNC-69 cooperates with UNC-76 to regulate axonal outgrowth and normal presynaptic organization in Caenorhabditis elegans

scientific article

Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2.

scientific article

Translational Repression of C. elegans p53 by GLD-1 Regulates DNA Damage-Induced Apoptosis

Translational repression of C. elegans p53 by GLD-1 regulates DNA damage-induced apoptosis

scientific article published in February 2005

Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans

scientific article

URI-1 is required for DNA stability in C. elegans

scientific article published in February 2006

WormQTL--public archive and analysis web portal for natural variation data in Caenorhabditis spp.

scientific article

ccz-1 mediates the digestion of apoptotic corpses in C. elegans

scientific article published in June 2010

eor-1 and eor-2 are required for cell-specific apoptotic death in C. elegans

scientific article published in October 2004

jkk-1 and mek-1 regulate body movement coordination and response to heavy metals through jnk-1 in Caenorhabditis elegans

scientific article

mProphet: automated data processing and statistical validation for large-scale SRM experiments

scientific article

miRNAs and apoptosis: RNAs to die for.

scientific article published on October 2006

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