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List of works by Ralf Küppers

A comprehensive genetic and histopathologic analysis identifies two subgroups of B-cell malignancies carrying a t(14;19)(q32;q13) or variant BCL3-translocation

scientific article published on 10 May 2007

A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms

scientific article

A human monoclonal IgA rheumatoid factor using the VkIV light chain gene

scientific article

A large fraction of human tonsillar B cells expressing CD27 are germinal center B cells

scientific article published on 3 February 2015

A microRNA involved in the germinal center reaction

scientific article published on July 2014

A model for the development of human IgD-only B cells: Genotypic analyses suggest their generation in superantigen driven immune responses

scientific article published on 25 October 2008

A novel immunohistochemical classifier to distinguish Hodgkin lymphoma from ALK anaplastic large cell lymphoma

scientific article

A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma

scientific article

A somatically mutated V kappa IV gene encoding a human rheumatoid factor light chain

scientific article

A strong host response and lack of MYC expression are characteristic for diffuse large B cell lymphoma transformed from nodular lymphocyte predominant Hodgkin lymphoma

scientific article

Aberrant expression of ID2, a suppressor of B-cell-specific gene expression, in Hodgkin's lymphoma

scientific article published on August 2006

Absence of immunoglobulin class switch in primary lymphomas of the central nervous system

scientific article

Absence of measles virus genome and transcripts in Hodgkin-Reed/Sternberg cells of a cohort of Hodgkin lymphoma patients

scientific article published on July 2007

Advances in biology, diagnostics, and treatment of Hodgkin's disease

scientific article

Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis

scientific article

Alterations of the CD58 gene in classical Hodgkin lymphoma

scientific article published on 21 July 2015

Amplification of TCRbeta gene rearrangements from micromanipulated single cells: T cells rosetting around Hodgkin and Reed-Sternberg cells in Hodgkin's disease are polyclonal

scientific article published in August 1998

Analysis of T-cell subpopulations in T-cell non-Hodgkin's lymphoma of angioimmunoblastic lymphadenopathy with dysproteinemia type by single target gene amplification of T cell receptor- beta gene rearrangements

scientific article published on May 2001

Analysis of a clonally related mantle cell and Hodgkin lymphoma indicates Epstein-Barr virus infection of a Hodgkin/Reed-Sternberg cell precursor in a germinal center

scientific article published in November 2003

Analysis of immunoglobulin gene rearrangements in single B cells

scientific article published on April 1995

Analyzing primary Hodgkin and Reed-Sternberg cells to capture the molecular and cellular pathogenesis of classical Hodgkin lymphoma

scientific article published on 5 September 2012

Apoptosis-resistant phenotype of classical Hodgkin's lymphoma is not mediated by somatic mutations within genes encoding members of the death-inducing signaling complex (DISC).

scientific article

Array-based DNA methylation analysis in classical Hodgkin lymphoma reveals new insights into the mechanisms underlying silencing of B cell-specific genes

article

Autocrine NGFbeta/TRKA signalling is an important survival factor for Hodgkin lymphoma derived cell lines

scientific article published on 27 July 2007

Autocrine- and paracrine-activated receptor tyrosine kinases in classic Hodgkin lymphoma

scientific article

B cells in chronically hepatitis C virus-infected individuals lack a virus-induced mutation signature in the TP53, CTNNB1, and BCL6 genes

scientific article published on 26 December 2012

B cells of chronic lymphatic leukemia express V genes in unmutated form

article

B cells under influence: transformation of B cells by Epstein–Barr virus ⬇️

scientific article published on October 1, 2003

B-cell development in progressively transformed germinal centers: similarities and differences compared with classical germinal centers and lymphocyte-predominant Hodgkin disease

scientific article (publication date: February 2001)

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

scientific article

BCL2 and BCL3 are recurrent translocation partners of the IGH locus

scientific article published on 01 October 2008

BLUEPRINT to decode the epigenetic signature written in blood.

scientific article

Biased IGH VDJ gene repertoire and clonal expansions in B cells of chronically hepatitis C virus-infected individuals

scientific article published on 14 December 2017

Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma

scientific article

Biology of Hodgkin's lymphoma

scientific article

Burkitt's lymphoma is a malignancy of mature B cells expressing somatically mutated V region genes

scientific article published on July 1995

CCR7 & lymphotoxin in lymphoma niche

scientific article published on 01 July 2011

CD303 (BDCA-2) signals in plasmacytoid dendritic cells via a BCR-like signalosome involving Syk, Slp65 and PLCgamma2.

scientific article published in December 2007

CD5-positive B cells in healthy elderly humans are a polyclonal B cell population

scientific article published on 01 October 2000

CD81 as target for B cell lymphomas

scientific article published on 06 June 2019

CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production

scientific article

Cellular origin and pathophysiology of chronic lymphocytic leukemia

scientific article published on 22 October 2012

Cellular origin of human B-cell lymphomas.

scientific article

Characterization of genomic imbalances in diffuse large B-cell lymphoma by detailed SNP-chip analysis

scientific article published on 22 July 2014

Chromosomal Breakpoints Affecting Immunoglobulin Loci Are Recurrent in Hodgkin and Reed-Sternberg Cells of Classical Hodgkin Lymphoma

scientific article published on 01 November 2006

Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma

scientific article

Clonality and germinal centre B-cell derivation of Hodgkin/Reed-Sternberg cells in Hodgkin's disease

scientific article published on 01 January 1998

Clonally related splenic marginal zone lymphoma and Hodgkin lymphoma with unmutated V gene rearrangements and a 15-yr time gap between diagnoses.

scientific article published in September 2004

Clonotypic B cells in classic Hodgkin lymphoma

scientific article published on 01 October 2009

Common features and differences in the transcriptome of large cell anaplastic lymphoma and classical Hodgkin's lymphoma.

scientific article

Common germinal-center B-cell origin of the malignant cells in two composite lymphomas, involving classical Hodgkin's disease and either follicular lymphoma or B-CLL.

scientific article

Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centers

scientific article

Concepts in mature T-cell lymphomas - highlights from an international joint symposium on T-cell immunology and oncology.

scientific article

Critical influences on the pathogenesis of follicular lymphoma

scientific article published on 17 April 2018

DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia

scientific article published on 18 January 2016

DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control

scientific article

Detection of clonal B cell populations in paraffin-embedded tissues by polymerase chain reaction.

scientific article published on July 1993

Detection of clonal Hodgkin and Reed-Sternberg cells with identical somatically mutated and rearranged VH genes in different biopsies in relapsed Hodgkin's disease

scientific article published in October 1998

Detection of clonal immunoglobulin rearrangements in paraffin embedded tissues by PCR

scientific article

Detection of clonal lambda light chain gene rearrangements in frozen and paraffin-embedded tissues by polymerase chain reaction.

scientific article published on September 1995

Detection of genomic aberrations in molecularly defined Burkitt's lymphoma by array-based, high resolution, single nucleotide polymorphism analysis

scientific article

Detection of genomic imbalances in microdissected Hodgkin and Reed-Sternberg cells of classical Hodgkin's lymphoma by array-based comparative genomic hybridization.

scientific article

Detection of identical Hodgkin-Reed Sternberg cell specific immunoglobulin gene rearrangements in a patient with Hodgkin's disease of mixed cellularity subtype at primary diagnosis and in relapse two and a half years later

scientific article published on March 1998

Differential protein stability and ALK inhibitor sensitivity of EML4-ALK fusion variants.

scientific article

Dysregulation of global microRNA expression in splenic marginal zone lymphoma and influence of chronic hepatitis C virus infection.

scientific article

EBV transformation overrides gene expression patterns of B cell differentiation stages

scientific article

EBV-infected B cells in infectious mononucleosis: viral strategies for spreading in the B cell compartment and establishing latency

scientific article published in October 2000

Epstein-Barr virus (EBV)-positive lymphoproliferations in post-transplant patients show immunoglobulin V gene mutation patterns suggesting interference of EBV with normal B cell differentiation processes

scientific article published in June 2003

Epstein-Barr virus-infected B cells expanding in germinal centers of infectious mononucleosis patients do not participate in the germinal center reaction

scientific article

Evidence for a large compartment of IgM-expressing memory B cells in humans.

scientific article published in February 1997

Expression of the IRTA1 receptor identifies intraepithelial and subepithelial marginal zone B cells of the mucosa-associated lymphoid tissue (MALT).

scientific article

Fibroblasts in Nodular Sclerosing Classical Hodgkin Lymphoma Are Defined by a Specific Phenotype and Protect Tumor Cells from Brentuximab-Vedotin Induced Injury

scientific article published on 30 October 2019

Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma

scientific article published on 26 September 2016

Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

scientific article

From pathogenesis to treatment of chronic lymphocytic leukaemia

scientific article published on 03 December 2009

Functional capacities of human IgM memory B cells in early inflammatory responses and secondary germinal center reactions

scientific article

Gene dosage effects in chronic lymphocytic leukemia

scientific article published in December 2010

Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma.

scientific article

Genetic evidence for latent Septata intestinalis infection in human immunodeficiency virus-infected patients with intestinal microsporidiosis

scientific article published in April 1996

Genetic lesions of the TRAF3 and MAP3K14 genes in classical Hodgkin lymphoma

scientific article

Genomic and epigenomic co-evolution in follicular lymphomas

article

Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma

scientific article published on 29 March 2019

Global correlation of genome and transcriptome changes in classical Hodgkin lymphoma

scientific article published in March 2007

High expression of several tyrosine kinases and activation of the PI3K/AKT pathway in mediastinal large B cell lymphoma reveals further similarities to Hodgkin lymphoma

scientific article published on 01 April 2007

High resolution SNP array genomic profiling of peripheral T cell lymphomas, not otherwise specified, identifies a subgroup with chromosomal aberrations affecting the REL locus

scientific article

Highly recurrent mutations of SGK1, DUSP2 and JUNB in nodular lymphocyte predominant Hodgkin lymphoma.

scientific article published on 10 December 2015

Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells.

scientific article

Hodgkin and Reed-Sternberg-like cells in B-cell chronic lymphocytic leukemia represent the outgrowth of single germinal-center B-cell-derived clones: potential precursors of Hodgkin and Reed-Sternberg cells in Hodgkin's disease.

scientific article published on February 2000

Hodgkin lymphoma

scientific article

Hodgkin lymphoma: Pathology and biology

scientific article

Hodgkin's disease: clonal Ig gene rearrangements in Hodgkin and Reed-Sternberg cells picked from histological sections

article

Hodgkin-Reed-Sternberg cells in classical Hodgkin lymphoma show alterations of genes encoding the NADPH oxidase complex and impaired reactive oxygen species synthesis capacity

scientific article

Hodgkin-Zellen sind klonale B-Zellen auf unterschiedlichen Stufen der Entwicklung

scientific article published on 01 March 1995

Human IgA- and IgM-secreting intestinal plasma cells carry heavily mutated VH region genes

scientific article published in September 1998

Human IgM+IgD+ B cells, the major B cell subset in the peripheral blood, express V kappa genes with no or little somatic mutation throughout life

scientific article published in December 1993

Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells

scientific article published on November 1998

Human memory B cells

scientific article

Human memory B cells: memory B cells of a special kind

scientific article published on 12 August 2008

Human splenic marginal zone B cells lack expression of activation-induced cytidine deaminase

scientific article published in October 2005

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

scientific article (publication date: 19 July 2001)

IRAK4 inhibition to shut down TLR signaling in autoimmunity and MyD88-dependent lymphomas

scientific article published on December 2015

Identification of Hodgkin and Reed-Sternberg cell-specific genes by gene expression profiling

scientific article

Identification of candidate tumour suppressor gene loci for Hodgkin and Reed-Sternberg cells by characterisation of homozygous deletions in classical Hodgkin lymphoma cell lines

scientific article published on 30 July 2008

Identification of common germinal-center B-cell precursors in two patients with both Hodgkin's disease and non-Hodgkin's lymphoma

scientific article published on April 1999

Identifying Genetic Lesions in Ocular Adnexal Extranodal Marginal Zone Lymphomas of the MALT Subtype by Whole Genome, Whole Exome and Targeted Sequencing

scientific article published on 17 April 2020

Identifying the precursors of Hodgkin and Reed-Sternberg cells in Hodgkin's disease: role of the germinal center in B-cell lymphomagenesis

scientific article

Immunoglobulin heavy and light chain gene sequences of a human CD5 positive immunocytoma and sequences of four novel VHIII germline genes

scientific article published in September 1992

Immunoglobulin repertoire of primary lymphomas of the central nervous system

scientific article published in December 2014

Inactivating SOCS1 mutations are caused by aberrant somatic hypermutation and restricted to a subset of B-cell lymphoma entities.

scientific article

Incomplete cytokinesis and re-fusion of small mononucleated Hodgkin cells lead to giant multinucleated Reed-Sternberg cells

scientific article

Indications for peripheral light-chain revision and somatic hypermutation without a functional B-cell receptor in precursors of a composite diffuse large B-cell and Hodgkin's lymphoma

scientific article published on February 2004

Insights into the multistep transformation process of lymphomas: IgH-associated translocations and tumor suppressor gene mutations in clonally related composite Hodgkin's and non-Hodgkin's lymphomas

article

Intrahepatic B-cell follicles of chronically hepatitis C virus-infected individuals lack signs of an ectopic germinal center reaction.

scientific article published on 14 April 2014

Isolation of viable Hodgkin and Reed-Sternberg cells from Hodgkin disease tissues

scientific article

L&H Cells in Lymphocyte-Predominant Hodgkin's Disease

scientific article published on 01 March 1998

Lack of deleterious somatic mutations in the CD95 gene of plasmablasts from systemic lupus erythematosus patients and autoantibody-producing cell lines

scientific article published on December 2002

Lack of somatic hypermutation of IG V(H) genes in lymphoid malignancies with t(2;14)(p13;q32) translocation involving the BCL11A gene

scientific article

Laser-based microdissection of single cells from tissue sections and PCR analysis of rearranged immunoglobulin genes from isolated normal and malignant human B cells

scientific article

Loss of the B-lineage-specific gene expression program in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma

scientific article

Lymphocyte predominant cells detect Moraxella catarrhalis-derived antigens in nodular lymphocyte-predominant Hodgkin lymphoma

scientific article published on 18 May 2020

MDM4 Is Targeted by 1q Gain and Drives Disease in Burkitt Lymphoma

scientific article published on 18 April 2019

MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells

scientific article

MYC/MIZ1-dependent gene repression inversely coordinates the circadian clock with cell cycle and proliferation.

scientific article

Macrophages in T cell/histiocyte rich large B cell lymphoma strongly express metal-binding proteins and show a bi-activated phenotype

scientific article published on 29 June 2013

Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma

scientific article

Mechanisms of B-cell lymphoma pathogenesis

scientific article

Mechanisms of aberrant GATA3 expression in classical Hodgkin lymphoma and its consequences for the cytokine profile of Hodgkin and Reed/Sternberg cells

scientific article published on 26 July 2010

Mechanisms of chromosomal translocations in B cell lymphomas

scientific article

Migration Properties Distinguish Tumor Cells of Classical Hodgkin Lymphoma from Anaplastic Large Cell Lymphoma Cells

scientific article published on 02 October 2019

Modern concepts in the biology, diagnosis, differential diagnosis and treatment of primary central nervous system lymphoma.

scientific article published on 05 August 2011

Molecular Ig gene analysis reveals that monocytoid B cell lymphoma is a malignancy of mature B cells carrying somatically mutated V region genes and suggests that rearrangement of the kappa-deleting element (resulting in deletion of the Ig kappa enh

scientific article published in August 1996

Molecular Single-Cell Analysis of Hodgkin- and Reed-Sternberg Cells Harboring Unmutated Immunoglobulin Variable Region Genes

article

Molecular analysis of IgD-positive human germinal centres

scientific article published on 5 February 2010

Molecular analysis of single B cells from T-cell-rich B-cell lymphoma shows the derivation of the tumor cells from mutating germinal center B cells and exemplifies means by which immunoglobulin genes are modified in germinal center B cells

scientific article published in April 1999

Molecular biology of Hodgkin lymphoma

scientific article

Molecular biology of Hodgkin's and Reed/Sternberg cells in Hodgkin's lymphoma

scientific article

Molecular biology of Hodgkin's lymphoma

scientific article

Molecular footprints of a germinal center derivation of human IgM+(IgD+)CD27+ B cells and the dynamics of memory B cell generation

scientific article published on 16 November 2009

Molecular pathogenesis of Hodgkin's lymphoma

scientific article

Molecular single cell analysis demonstrates the derivation of a peripheral blood-derived cell line (L1236) from the Hodgkin/Reed-Sternberg cells of a Hodgkin's lymphoma patient.

scientific article published on April 1996

Molecular single cell studies of normal and transformed lymphocytes

scientific article published on January 1997

Molecular single-cell PCR analysis of rearranged immunoglobulin genes as a tool to determine the clonal composition of normal and malignant human B cells

scientific article

Molecular single-cell analysis of Hodgkin and Reed-Sternberg cells

scientific article published on April 1995

Molecular single-cell analysis of the clonal relationship of small Epstein-Barr virus-infected cells and Epstein-Barr virus-harboring Hodgkin and Reed/Sternberg cells in Hodgkin disease

scientific article published in November 2000

Molecular single-cell analysis reveals that CD5-positive peripheral blood B cells in healthy humans are characterized by rearranged Vkappa genes lacking somatic mutation.

scientific article published on October 1997

Mutation analysis of the TNFAIP3 (A20) tumor suppressor gene in CLL

article

Mutation of the p53 gene is not a typical feature of Hodgkin and Reed-Sternberg cells in Hodgkin's disease

article

Mutational analysis of the IkappaBalpha gene in activated B cell-like diffuse large B-cell lymphoma

scientific article published in July 2004

Mutations in the genes coding for the NF-κB regulating factors IκBα and A20 are uncommon in nodular lymphocyte-predominant Hodgkin's lymphoma

scientific article

Mutations of CARD11 but not TNFAIP3 may activate the NF-kappaB pathway in primary CNS lymphoma

scientific article published on 11 June 2010

NF-κB deregulation in Hodgkin lymphoma

scientific article published on 21 May 2016

NPAT mutations in Hodgkin lymphoma

scientific article published on 01 July 2011

New insights in the biology of Hodgkin lymphoma

scientific article published on January 1, 2012

New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling

scientific article

Nodular lymphocyte predominant hodgkin lymphoma and T cell/histiocyte rich large B cell lymphoma--endpoints of a spectrum of one disease?

scientific article

Normal and malignant B-cell development with special reference to Hodgkin's disease

scientific article published on January 1997

Novel IGH and MYC Translocation Partners in Diffuse Large B-Cell Lymphomas

scientific article published on 29 June 2016

Ongoing somatic mutation in mantle cell lymphomas questioned

scientific article published on 01 June 1997

Origin and pathogenesis of B cell lymphomas

scientific article published on January 2013

Origin and pathogenesis of nodular lymphocyte-predominant Hodgkin lymphoma as revealed by global gene expression analysis

scientific article published on 15 September 2008

PLK1-dependent phosphorylation restrains EBNA2 activity and lymphomagenesis in EBV-infected mice

scientific article published on 04 October 2021

Pathogenesis of Hodgkin's lymphoma.

scientific article

Pathogenesis of classical and lymphocyte-predominant Hodgkin lymphoma

scientific article published on January 2009

Pathogenesis, diagnosis, and treatment of composite lymphomas

scientific article published on September 2014

Pathology and "molecular histology' of Hodgkin's disease and the border to non-Hodgkin's lymphomas

scientific article

Phenotypic and molecular characterization of human peripheral blood B-cell subsets with special reference to N-region addition and J kappa-usage in V kappa J kappa-joints and kappa/lambda-ratios in naive versus memory B-cell subsets to identify trac

scientific article published in January 1999

Potential role of hypoxia in early stages of Hodgkin lymphoma pathogenesis

scientific article published on 9 July 2015

Preferential expression of truncated isoforms of FOXP1 in primary central nervous system lymphoma.

scientific article published in September 2009

Primary central nervous system lymphomas are derived from germinal-center B cells and show a preferential usage of the V4-34 gene segment

scientific article published on December 1999

Profiling of Hodgkin's lymphoma cell line L1236 and germinal center B cells: identification of Hodgkin's lymphoma-specific genes

scientific article

Prognosis in Follicular Lymphoma — It's in the Microenvironment

scientific article published on 01 November 2004

Prognostic significance of Epstein-Barr virus-infected cells in the bone marrow of patients with nasal natural killer/T cell lymphoma

scientific article

Quantitative Comparison of Abundance Structures of Generalized Communities: From B-Cell Receptor Repertoires to Microbiomes

scientific article

RETRACTED: Silencing of B cell receptor signals in human naive B cells

retracted scientific article

Rare occurrence of biallelic CYLD gene mutations in classical Hodgkin lymphoma

scientific article

Rare occurrence of classical Hodgkin's disease as a T cell lymphoma

scientific article published on January 2000

Receptor revision plays no major role in shaping the receptor repertoire of human memory B cells after the onset of somatic hypermutation

scientific article

Recurrent Inactivation of the PRDM1 Gene in Primary Central Nervous System Lymphoma

article

Recurrent alterations ofTNFAIP3(A20) in T-cell large granular lymphocytic leukemia

scientific article published on 30 July 2015

Recurrent deletions of the TNFSF7 and TNFSF9 genes in 19p13.3 in diffuse large B-cell and Burkitt lymphomas

scientific article

Recurrent mutation of JAK3 in T-cell prolymphocytic leukemia

scientific article published on 21 January 2014

Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

scientific article

Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomas

scientific article published on 23 August 2016

Regulation of immunoglobulin light chain gene rearrangements during early B cell development in the human

scientific article published on 01 December 2001

Regulation of immunoglobulin light chain gene rearrangements during early B cell development in the human

scholarly article by Andreas Bräuninger et al published December 2001 in European Journal of Immunology

Report of a workshop on malignant lymphoma: a review of molecular and clinical risk profiling

scientific article published on 19 May 2008

Reprogramming of the tumour B-cell phenotype in Hodgkin lymphoma

scientific article published on 23 March 2006

Retraction

Role of early B-cell factor 1 (EBF1) in Hodgkin lymphoma

scientific article published on October 2012

Role of hepatitis C virus in B cell lymphoproliferations

scientific article published on February 2014

Role of microRNAs in B cell leukemias and lymphomas

scientific article published on January 2014

Side population cells in Hodgkin lymphoma

scientific article published on 01 May 2010

Signatures of mutational processes in human cancer

scientific article (publication date: 22 August 2013)

Single cell analysis of Hodgkin/Reed-Sternberg cells

scientific article published on January 1996

Single-cell PCR analysis of T helper cells in human lymph node germinal centers

scientific article published on March 2000

Somatic Hypermutation and B Cell Receptor Selection in Normal and Transformed Human B Cells ⬇️

scientific article published on April 1, 2003

Somatic hypermutation in normal and transformed human B cells

scientific article published in April 1998

Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction

scientific article published on December 2000

Somatic mutations within the untranslated regions of rearranged Ig genes in a case of classical Hodgkin's disease as a potential cause for the absence of Ig in the lymphoma cells

scientific article published on June 1999

Structure and diversification of immunoglobulin genes in African Burkitt lymphoma

article

Subclonal evolution of a classical Hodgkin lymphoma from a germinal center B-cell-derived mantle cell lymphoma

scientific article

Survival and clonal expansion of mutating "forbidden" (immunoglobulin receptor-deficient) epstein-barr virus-infected b cells in angioimmunoblastic t cell lymphoma.

scientific article

TET2 mutations in B cells of patients affected by angioimmunoblastic T-cell lymphoma

scientific article published on 24 March 2017

THE ORIGIN OF HODGKIN AND REED/STERNBERG CELLS IN HODGKIN'S DISEASE

TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma

scientific article

Telomeres and prognosis in patients with chronic lymphocytic leukaemia

scientific article published on 05 January 2011

The GNAS1 T393C polymorphism is associated with disease progression and survival in chronic lymphocytic leukemia

scientific article published in October 2006

The Hodgkin and Reed/Sternberg cell

scientific article

The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery

scientific article

The PRDX2 gene is transcriptionally silenced and de novo methylated in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma

article

The aberrant coexpression of several receptor tyrosine kinases is largely restricted to EBV-negative cases of classical Hodgkin's lymphoma

scientific article published on 01 June 2007

The biology of Hodgkin's lymphoma

scientific article published on 11 December 2008

The expression of activation induced cytidine deaminase in follicular lymphoma is independent of prognosis and stage

scientific article published in March 2009

The major subtypes of human B-cell lymphomas lack mutations in BCL-2 family member BAD.

scientific article published on October 2006

The origin of CD95-gene mutations in B-cell lymphoma

scientific article published in February 2002

The prognostic significance of soluble NKG2D ligands in B-cell chronic lymphocytic leukemia

scientific article published on 29 April 2010

The role of T cells in the microenvironment of Hodgkin lymphoma

scientific article published on 28 August 2015

The role of somatic hypermutation in the generation of deletions and duplications in human Ig V region genes and chromosomal translocations

scientific article

Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections

scientific article

Transcriptional Profiling of the Nuclear Factor-κB Pathway Identifies a Subgroup of Primary Lymphoma of the Central Nervous System With Low BCL10 Expression

scientific article published on 01 March 2007

Transformation of BCR-deficient germinal-center B cells by EBV supports a major role of the virus in the pathogenesis of Hodgkin and posttransplantation lymphomas

scientific article

Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults

scientific article published on 12 April 2011

Trisomy 19 is associated with trisomy 12 and mutatedIGHVgenes in B-chronic lymphocytic leukaemia

scientific article published on 01 July 2007

Tumor cell dissemination in follicular lymphoma

scientific article published on 01 March 2002

Tumor-infiltrating HLA-matched CD4(+) T cells retargeted against Hodgkin and Reed-Sternberg cells

scientific article published on 16 March 2016

Typing the histogenetic origin of the tumor cells of lymphocyte-rich classical Hodgkin's lymphoma in relation to tumor cells of classical and lymphocyte-predominance Hodgkin's lymphoma.

scientific article

Variable region gene analysis of B cell subsets derived from a 4-year-old child: somatically mutated memory B cells accumulate in the peripheral blood already at young age.

scientific article published on October 1994

Variable-region gene analysis of B-cell subsets derived from a 4-year-old child. Somatically mutated memory B cells accumulate in the peripheral blood already at young age.

scientific article

Whole exome sequencing of microdissected splenic marginal zone lymphoma: a study to discover novel tumor-specific mutations

scientific article

Whole-genome fingerprint of the DNA methylome during human B cell differentiation

scientific article

[Global gene expression analysis and novel signalling pathways in Hodgkin lymphoma]

scientific article published on 01 January 2006

p53 protein expression in chronic lymphocytic leukemia

scientific article published on 13 February 2012

γδ T-cell Receptors Derived from Breast Cancer-Infiltrating T Lymphocytes Mediate Antitumor Reactivity

scientific article published on 04 February 2020

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