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List of works by Frank Bradke

A Dual SILAC Proteomic Labeling Strategy for Quantifying Constitutive and Cell-Cell Induced Protein Secretion.

scientific article published on 20 July 2015

A chemical screen identifies novel compounds that overcome glial-mediated inhibition of neuronal regeneration.

scientific article

A new "spin" on recovery after spinal cord injury

scientific article published on 01 December 2014

A simple method for 3D analysis of immunolabeled axonal tracts in a transparent nervous system.

scientific article published on 6 November 2014

AAV-mediated expression of BAG1 and ROCK2-shRNA promote neuronal survival and axonal sprouting in a rat model of rubrospinal tract injury

scientific article published on 13 April 2015

ADF/Cofilin-Mediated Actin Turnover Promotes Axon Regeneration in the Adult CNS

scientific article published on 07 August 2019

Accumulation of glucosylceramide in the absence of the beta-glucosidase GBA2 alters cytoskeletal dynamics.

scientific article

An assay to image neuronal microtubule dynamics in mice

scientific article

Assembly of a new growth cone after axotomy: the precursor to axon regeneration ⬇️

scientific article published on February 15, 2012

Axon Regeneration in the Central Nervous System: Facing the Challenges from the Inside

scientific article published on 25 July 2018

Axonal regeneration. Systemic administration of epothilone B promotes axon regeneration after spinal cord injury

scientific article

Beneficial "Pharmaceutical Pleiotropy" of Gabapentinoids in Spinal Cord Injury: A Case for Refining Standard-of-Care

scientific article published on 07 June 2020

Can injured adult CNS axons regenerate by recapitulating development?

scientific article published in October 2017

Cdc42 regulates cofilin during the establishment of neuronal polarity.

scientific article published in November 2007

Changes in membrane trafficking and actin dynamics during axon formation in cultured hippocampal neurons

scientific article

Chronically CNS-injured adult sensory neurons gain regenerative competence upon a lesion of their peripheral axon.

scientific article

Controlled Demolition: Smurf1 Regulates Neuronal Polarity by Substrate Switching ⬇️

scientific article published on January 27, 2011

Coordinating neuronal actin-microtubule dynamics

scientific article (publication date: 3 August 2015)

Cytoplasmic linker proteins regulate neuronal polarization through microtubule and growth cone dynamics.

scientific article published on January 2011

Cytoskeleton dynamics in axon regeneration

scientific article published on 12 March 2018

Differentiated neurons retain the capacity to generate axons from dendrites

scientific article published in November 2000

Disorganized microtubules underlie the formation of retraction bulbs and the failure of axonal regeneration.

scientific article published in August 2007

Editorial overview: development and regeneration: nervous system development and regeneration

scientific article

Electrical activity suppresses axon growth through Ca(v)1.2 channels in adult primary sensory neurons

scientific article published on 24 June 2010

Establishment of neuronal polarity: lessons from cultured hippocampal neurons

scientific article

Glutamatergic synaptic integration of locomotion speed via septoentorhinal projections

scientific article published on 28 November 2016

Growth cone-like waves transport actin and promote axonogenesis and neurite branching.

scientific article

High-resolution 3D imaging and analysis of axon regeneration in unsectioned spinal cord with or without tissue clearing

scientific article published on 22 March 2019

High-resolution imaging of entire organs by 3-dimensional imaging of solvent cleared organs (3DISCO).

scientific article

Imaging in vivo dynamics of sensory axon responses to CNS injury

scientific article published on 20 February 2019

Key attributes of successful research institutes

scientific article published in 2023

Lifeact: a versatile marker to visualize F-actin

scientific article (publication date: July 2008)

Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction.

scientific article published on 23 November 2016

Macroporous hydrogels derived from aqueous dynamic phase separation

scientific article published on 02 February 2019

Membrane traffic in polarized neurons

scientific article published on 01 August 1998

Microtubule Organization in the Axon: TRIM46 Determines the Orientation

scientific article published on 01 December 2015

Microtubule Stabilization Reduces Scarring and Causes Axon Regeneration After Spinal Cord Injury ⬇️

scientific article published on January 27, 2011

Microtubule self-organization via protein-RNA network crosstalk.

scientific article published in July 2014

Mouse model of CADASIL reveals novel insights into Notch3 function in adult hippocampal neurogenesis

scientific article published on 31 December 2014

Netrin-1 is a novel myelin-associated inhibitor to axon growth.

scientific article

Neuronal polarity: vectorial cytoplasmic flow precedes axon formation

scientific article published in December 1997

Neuronal polarization and the cytoskeleton ⬇️

scientific article published on August 22, 2011

Neuronal polarization: From spatiotemporal signaling to cytoskeletal dynamics

scientific article published on 28 March 2017

Neuronal polarization: the cytoskeleton leads the way.

scientific article published on June 2011

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules

scientific article published on 17 June 2019

PCAF-dependent epigenetic changes promote axonal regeneration in the central nervous system.

scientific article

Rac1 regulates neuronal polarization through the WAVE complex

scientific article published in May 2010

Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease

scientific article

Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation

scientific article published in June 2002

Reproducibility - The key towards clinical implementation of spinal cord injury treatments?

scientific article published on 31 December 2018

RhoA Controls Axon Extension Independent of Specification in the Developing Brain

scientific article published on 31 October 2019

Serum Response Factor (SRF)-cofilin-actin signaling axis modulates mitochondrial dynamics ⬇️

scientific article published on August 27, 2012

Single-cell axotomy of cultured hippocampal neurons integrated in neuronal circuits.

scientific article published on 3 April 2014

Spatial and temporal arrangement of neuronal intrinsic and extrinsic mechanisms controlling axon regeneration.

scientific article published on 28 December 2016

Species-specific differences in nonlysosomal glucosylceramidase GBA2 function underlie locomotor dysfunction arising from loss-of-function mutations

scientific article published on 20 January 2019

Spinal cord injury-induced immunodeficiency is mediated by a sympathetic-neuroendocrine adrenal reflex

scientific article

Systemic administration of epothilone D improves functional recovery of walking after rat spinal cord contusion injury.

scientific article

Systemic epothilone D improves hindlimb function after spinal cord contusion injury in rats.

scientific article published in February 2018

The Calcium Channel Subunit Alpha2delta2 Suppresses Axon Regeneration in the Adult CNS.

scientific article published on 27 September 2016

The DLK signalling pathway--a double-edged sword in neural development and regeneration

scientific article

The Effect of Non-Gabapentinoid Anticonvulsants on Sensorimotor Recovery After Human Spinal Cord Injury

scientific article published on 01 May 2019

The centrosome protein AKNA regulates neurogenesis via microtubule organization

scientific article published on 20 February 2019

Therapeutic repair for spinal cord injury: combinatory approaches to address a multifaceted problem

scientific article published on 24 February 2020

Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis

scientific article published on 01 October 2018

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