List of works - Pura Muñoz Cánoves

A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart

scientific article published on 09 September 2020

Aberrant repair and fibrosis development in skeletal muscle

scientific article published on 4 May 2011

Aged Stem Cells Reprogram Their Daily Rhythmic Functions to Adapt to Stress

scientific article published in August 2017

Aging, metabolism and stem cells: Spotlight on muscle stem cells

scientific article published on 12 August 2016

Alpha-enolase plasminogen receptor in myogenesis

scientific article

Amelioration of Duchenne muscular dystrophy in mdx mice by elimination of matrix-associated fibrin-driven inflammation coupled to the αMβ2 leukocyte integrin receptor

scientific article

Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis Is Required for Efficient Regeneration of Dystrophic Muscles

scientific article published on 01 May 2020

Author Correction: Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration

scientific article published in 2023

Autophagy maintains stemness by preventing senescence

scientific article published on January 2016

Autophagy maintains stemness by preventing senescence

scientific article published in Nature

Autophagy: a decisive process for stemness

scientific article

Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch

scientific article published on 5 December 2014

Brain-muscle communication prevents muscle aging by maintaining daily physiology

scientific article published on 02 May 2024

Cell transcriptomic atlas of the non-human primate Macaca fascicularis

scientific article published on 13 April 2022

Cellular Senescence Is Associated With Human Retinal Microaneurysm Formation During Aging.

scientific article published in June 2017

Cellular and molecular mechanisms regulating fibrosis in skeletal muscle repair and disease

scientific article published on January 2011

Chromatin-wide and transcriptome profiling integration uncovers p38α MAPK as a global regulator of skeletal muscle differentiation

scientific article

Cilia Control Fat Deposition during Tissue Repair.

scientific article

Cripto shapes macrophage plasticity and restricts EndMT in injured and diseased skeletal muscle

scientific article published on 27 February 2020

Definitions for adult stem cells debated

scientific article published in Nature

Dual mTORC1/C2 inhibitors: gerosuppressors with potential anti-aging effect

scientific article published on 15 September 2015

Dysfunctional autophagy is a driver of muscle stem cell functional decline with aging.

scientific article published on 18 February 2016

E47 phosphorylation by p38 MAPK promotes MyoD/E47 association and muscle-specific gene transcription

scientific article

Editorial: Role of Stem Cells in Skeletal Muscle Development, Regeneration, Repair, Aging, and Disease.

scientific article

Efficient adult skeletal muscle regeneration in mice deficient in p38beta, p38gamma and p38delta MAP kinases

scientific article published on 12 May 2008

Epigenetic control of adult skeletal muscle stem cell functions

scientific article published on 21 October 2014

Epigenetic regulation of myogenesis

scientific article

Fibrinogen drives dystrophic muscle fibrosis via a TGFbeta/alternative macrophage activation pathway

scientific article published in July 2008

Fibrinogen-Derived γ377-395 Peptide Improves Cognitive Performance and Reduces Amyloid-β Deposition, without Altering Inflammation, in AβPP/PS1 Mice.

scientific article

Fibrogenic Cell Plasticity Blunts Tissue Regeneration and Aggravates Muscular Dystrophy

scientific article published on 14 May 2015

Fibrosis development in early-onset muscular dystrophies: Mechanisms and translational implications

scientific article published on 23 September 2016

Fibrosis-Inducing Strategies in Regenerating Dystrophic and Normal Skeletal Muscle.

scientific article published in January 2016

FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age

scientific article published on 26 October 2020

Functional dysregulation of stem cells during aging: a focus on skeletal muscle stem cells

scientific article published on 21 March 2013

Genetic Rescue of Mitochondrial and Skeletal Muscle Impairment in an Induced Pluripotent Stem Cells Model of Coenzyme Q10 Deficiency.

scientific article published on 4 May 2017

Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation

scientific article published on 15 February 2007

Genetic deficiency of p38alpha reveals its critical role in myoblast cell cycle exit: the p38alpha-JNK connection

scientific article published on 20 June 2007

Geriatric muscle stem cells switch reversible quiescence into senescence.

scientific article

Geroconversion of aged muscle stem cells under regenerative pressure

scientific article published on January 2014

HIV-1 transgenic expression in mice induces selective atrophy of fast-glycolytic skeletal muscle fibers

scientific article published in January 2008

Inflammation in muscle repair, aging, and myopathies.

scientific article published on 4 August 2014

Integration of feeding behavior by the liver circadian clock reveals network dependency of metabolic rhythms

scientific article published on 22 September 2021

Interleukin-6 is an essential regulator of satellite cell-mediated skeletal muscle hypertrophy

scientific article

Interleukin-6 myokine signaling in skeletal muscle: a double-edged sword?

scientific article

Lack of Glycogenin Causes Glycogen Accumulation and Muscle Function Impairment.

scientific article

Large field of view-spatially resolved transcriptomics at nanoscale resolution

scientific article

MKP-1 coordinates ordered macrophage-phenotype transitions essential for stem cell-dependent tissue repair.

scientific article published in March 2012

Macrophage plasticity and the role of inflammation in skeletal muscle repair

scientific article published on 30 January 2013

Macrophages decide between regeneration and fibrosis in muscle

scientific article published on 03 August 2015

Mesenchymal Transitions in Development and Disease.

scientific article published on 02 August 2016

Methods for Mitochondria and Mitophagy Flux Analyses in Stem Cells of Resting and Regenerating Skeletal Muscle

scientific article published in January 2016

Monitoring Autophagy in Muscle Stem Cells

scientific article

Muscle stem cell aging: identifying ways to induce tissue rejuvenation

scientific article published on 17 April 2020

Muscle stem cell aging: regulation and rejuvenation

scientific article published on 10 April 2015

Musculoskeletal senescence: a moving target ready to be eliminated

scientific article published on 05 June 2018

New mechanisms driving muscle stem cell regenerative decline with aging

scientific article published on 01 January 2018

Novel and optimized strategies for inducing fibrosis in vivo: focus on Duchenne Muscular Dystrophy

scientific article published on 25 August 2014

PAI-1-regulated miR-21 defines a novel age-associated fibrogenic pathway in muscular dystrophy.

scientific article published on 2 January 2012

Phosphorylation of MRF4 transactivation domain by p38 mediates repression of specific myogenic genes

scientific article

Plasmin activity is required for myogenesis in vitro and skeletal muscle regeneration in vivo

scientific journal article

Plasmin generation dependent on alpha-enolase-type plasminogen receptor is required for myogenesis

scientific article published on 01 October 2003

Plasminogen activator inhibitor type-1 inhibits insulin signaling by competing with alphavbeta3 integrin for vitronectin binding.

scientific article published on March 2003

Proteostatic and Metabolic Control of Stemness

scientific article published on May 2017

Regenerative decline of stem cells in sarcopenia

scientific article published on 24 February 2016

Regulation and dysregulation of fibrosis in skeletal muscle

scientific article published on 04 June 2010

Regulation of Muscle Stem Cell Functions: A Focus on the p38 MAPK Signaling Pathway

scientific article

Regulation of skeletal muscle gene expression by p38 MAP kinases.

scientific article

Regulation of skeletal muscle stem cells through epigenetic mechanisms

scientific article published on May 2011

Rejuvenating stem cells to restore muscle regeneration in aging

scientific article published on 25 January 2017

Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration

scientific article published in 2022

Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals

scientific article published on 13 January 2020

Simultaneous Isolation of Stem and Niche Cells of Skeletal Muscle: Applicability for Aging Studies

scientific article published on 01 January 2019

Sox17 Controls Emergence and Remodeling of Nestin-Expressing Coronary Vessels

scientific article published on 14 September 2020

Special Issue: Epigenetics

scientific article published on 20 April 2015

Special issue: myogenesis: introduction

scientific article published on 14 August 2013

Stem Cells and Aging: What's Next?

scientific article

The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis

scientific article

The Dystrophin Glycoprotein Complex Regulates the Epigenetic Activation of Muscle Stem Cell Commitment.

scientific article published on 12 April 2018

The alkylating carcinogen N-methyl-N'-nitro-N-nitrosoguanidine activates the plasminogen activator inhibitor-1 gene through sequential phosphorylation of p53 by ATM and ATR kinases.

scientific article

The central clock suffices to drive the majority of circulatory metabolic rhythms

scientific article published in 2022

The ins and outs of muscle stem cell aging

scientific article

The plasminogen activation system in skeletal muscle regeneration: antagonistic roles of urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1).

scientific article

Transcriptional and posttranscriptional regulation of the plasminogen activator system.

scientific article published in April 2005

Understanding muscle regenerative decline with aging: new approaches to bring back youthfulness to aged stem cells

scientific article published on 03 January 2020

Understanding the process of fibrosis in Duchenne muscular dystrophy.

scientific article

p38 MAPK-induced nuclear factor-kappaB activity is required for skeletal muscle differentiation: role of interleukin-6.

scientific article published on 6 February 2004

p38/MKP-1-regulated AKT coordinates macrophage transitions and resolution of inflammation during tissue repair

scientific article

uPA deficiency exacerbates muscular dystrophy in MDX mice

scientific article

uPA deficiency exacerbates muscular dystrophy inMDXmice

scholarly article by Mònica Suelves et al published 8 October 2007 in Journal of Cell Biology

List of works by Pura Muñoz Cánoves

A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart

Aberrant repair and fibrosis development in skeletal muscle

Aged Stem Cells Reprogram Their Daily Rhythmic Functions to Adapt to Stress

Aging, metabolism and stem cells: Spotlight on muscle stem cells

Alpha-enolase plasminogen receptor in myogenesis

Amelioration of Duchenne muscular dystrophy in mdx mice by elimination of matrix-associated fibrin-driven inflammation coupled to the αMβ2 leukocyte integrin receptor

Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis Is Required for Efficient Regeneration of Dystrophic Muscles

Author Correction: Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration

Autophagy maintains stemness by preventing senescence

Autophagy maintains stemness by preventing senescence

Autophagy: a decisive process for stemness

Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch

Brain-muscle communication prevents muscle aging by maintaining daily physiology

Cell transcriptomic atlas of the non-human primate Macaca fascicularis

Cellular Senescence Is Associated With Human Retinal Microaneurysm Formation During Aging.

Cellular and molecular mechanisms regulating fibrosis in skeletal muscle repair and disease

Chromatin-wide and transcriptome profiling integration uncovers p38α MAPK as a global regulator of skeletal muscle differentiation

Cilia Control Fat Deposition during Tissue Repair.

Cripto shapes macrophage plasticity and restricts EndMT in injured and diseased skeletal muscle

Definitions for adult stem cells debated

Dual mTORC1/C2 inhibitors: gerosuppressors with potential anti-aging effect

Dysfunctional autophagy is a driver of muscle stem cell functional decline with aging.

E47 phosphorylation by p38 MAPK promotes MyoD/E47 association and muscle-specific gene transcription

Editorial: Role of Stem Cells in Skeletal Muscle Development, Regeneration, Repair, Aging, and Disease.

Efficient adult skeletal muscle regeneration in mice deficient in p38beta, p38gamma and p38delta MAP kinases

Epigenetic control of adult skeletal muscle stem cell functions

Epigenetic regulation of myogenesis

Fibrinogen drives dystrophic muscle fibrosis via a TGFbeta/alternative macrophage activation pathway

Fibrinogen-Derived γ377-395 Peptide Improves Cognitive Performance and Reduces Amyloid-β Deposition, without Altering Inflammation, in AβPP/PS1 Mice.

Fibrogenic Cell Plasticity Blunts Tissue Regeneration and Aggravates Muscular Dystrophy

Fibrosis development in early-onset muscular dystrophies: Mechanisms and translational implications

Fibrosis-Inducing Strategies in Regenerating Dystrophic and Normal Skeletal Muscle.

FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age

Functional dysregulation of stem cells during aging: a focus on skeletal muscle stem cells

Genetic Rescue of Mitochondrial and Skeletal Muscle Impairment in an Induced Pluripotent Stem Cells Model of Coenzyme Q10 Deficiency.

Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation

Genetic deficiency of p38alpha reveals its critical role in myoblast cell cycle exit: the p38alpha-JNK connection

Geriatric muscle stem cells switch reversible quiescence into senescence.

Geroconversion of aged muscle stem cells under regenerative pressure

HIV-1 transgenic expression in mice induces selective atrophy of fast-glycolytic skeletal muscle fibers

Inflammation in muscle repair, aging, and myopathies.

Integration of feeding behavior by the liver circadian clock reveals network dependency of metabolic rhythms

Interleukin-6 is an essential regulator of satellite cell-mediated skeletal muscle hypertrophy

Interleukin-6 myokine signaling in skeletal muscle: a double-edged sword?

Lack of Glycogenin Causes Glycogen Accumulation and Muscle Function Impairment.

Large field of view-spatially resolved transcriptomics at nanoscale resolution

MKP-1 coordinates ordered macrophage-phenotype transitions essential for stem cell-dependent tissue repair.

Macrophage plasticity and the role of inflammation in skeletal muscle repair

Macrophages decide between regeneration and fibrosis in muscle

Mesenchymal Transitions in Development and Disease.

Methods for Mitochondria and Mitophagy Flux Analyses in Stem Cells of Resting and Regenerating Skeletal Muscle

Monitoring Autophagy in Muscle Stem Cells

Muscle stem cell aging: identifying ways to induce tissue rejuvenation

Muscle stem cell aging: regulation and rejuvenation

Musculoskeletal senescence: a moving target ready to be eliminated

New mechanisms driving muscle stem cell regenerative decline with aging

Novel and optimized strategies for inducing fibrosis in vivo: focus on Duchenne Muscular Dystrophy

PAI-1-regulated miR-21 defines a novel age-associated fibrogenic pathway in muscular dystrophy.

Phosphorylation of MRF4 transactivation domain by p38 mediates repression of specific myogenic genes

Plasmin activity is required for myogenesis in vitro and skeletal muscle regeneration in vivo

Plasmin generation dependent on alpha-enolase-type plasminogen receptor is required for myogenesis

Plasminogen activator inhibitor type-1 inhibits insulin signaling by competing with alphavbeta3 integrin for vitronectin binding.

Proteostatic and Metabolic Control of Stemness

Regenerative decline of stem cells in sarcopenia

Regulation and dysregulation of fibrosis in skeletal muscle

Regulation of Muscle Stem Cell Functions: A Focus on the p38 MAPK Signaling Pathway

Regulation of skeletal muscle gene expression by p38 MAP kinases.

Regulation of skeletal muscle stem cells through epigenetic mechanisms

Rejuvenating stem cells to restore muscle regeneration in aging

Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration

Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals

Simultaneous Isolation of Stem and Niche Cells of Skeletal Muscle: Applicability for Aging Studies

Sox17 Controls Emergence and Remodeling of Nestin-Expressing Coronary Vessels

Special Issue: Epigenetics

Special issue: myogenesis: introduction

Stem Cells and Aging: What's Next?

The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis

The Dystrophin Glycoprotein Complex Regulates the Epigenetic Activation of Muscle Stem Cell Commitment.

The alkylating carcinogen N-methyl-N'-nitro-N-nitrosoguanidine activates the plasminogen activator inhibitor-1 gene through sequential phosphorylation of p53 by ATM and ATR kinases.