List of works - Steven Rosenberg

Cancer regression in patients after transfer of genetically engineered lymphocytes

scientific article

Cancer immunotherapy: moving beyond current vaccines

scientific article

A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer

scientific article published on July 2003

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

scientific article

T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

scientific article published on October 13, 2014

Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy

scientific article

A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone

scientific article published on 01 April 1987

Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer

scientific article

Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens

scientific article

Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma

scientific article

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

scientific article

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

scientific article

Adoptive immunotherapy for cancer: harnessing the T cell response

scientific article

Adoptive cell transfer: a clinical path to effective cancer immunotherapy

scientific article

B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cells

scientific article (publication date: 22 March 2012)

Adoptive cell transfer as personalized immunotherapy for human cancer

scientific article published in April 2015

Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report

scientific article published on 01 December 1988

Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired

scientific article

Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.

scientific article

Chemotherapy-Refractory Diffuse Large B-Cell Lymphoma and Indolent B-Cell Malignancies Can Be Effectively Treated With Autologous T Cells Expressing an Anti-CD19 Chimeric Antigen Receptor

scientific article published on August 25, 2014

Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer

scientific article published in Science

Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19

scientific article published on July 28, 2010

Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells

scientific article

A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer

scientific article

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells

scientific article

Adoptive immunotherapy for cancer: building on success

scientific article

Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells

scientific article

Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy

scientific article published on February 2013

Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4.

scientific article

T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis.

scientific article

Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells

scientific article

Gene transfer into humans--immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction

scientific article

gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma

scientific article

Phase 2 Trial of Single Agent Ipilimumab (Anti-CTLA-4) for Locally Advanced or Metastatic Pancreatic Adenocarcinoma

article by Richard E Royal et al published October 2010 in Journal of Immunotherapy

Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes

scientific article

PD-1 identifies the patient-specific CD8⁺ tumor-reactive repertoire infiltrating human tumors

scientific article published on 25 March 2014

CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.

scientific article

Adoptive cell therapy for the treatment of patients with metastatic melanoma

scientific article

Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4

scientific article

Exome sequencing identifies GRIN2A as frequently mutated in melanoma

scientific article

Adoptive-cell-transfer therapy for the treatment of patients with cancer

scientific article

Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer

scientific article

Ipilimumab (anti-CTLA4 antibody) causes regression of metastatic renal cell cancer associated with enteritis and hypophysitis

scientific article

Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients

scientific article published on July 2003

CTLA-4 Blockade with Ipilimumab: Long-term Follow-up of 177 Patients with Metastatic Melanoma

scientific article published on January 23, 2012

Cutting edge: persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy

scientific article

The natural history of initially untreated low-grade non-Hodgkin's lymphomas

scientific article published on 01 December 1984

Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients

scientific article published on 22 February 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer.

scientific article

IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients

scientific article

List of works by Steven Rosenberg

Cancer regression in patients after transfer of genetically engineered lymphocytes

Cancer immunotherapy: moving beyond current vaccines

A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy

A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone

Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer

Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens

Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

Adoptive immunotherapy for cancer: harnessing the T cell response

Adoptive cell transfer: a clinical path to effective cancer immunotherapy

B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cells

Adoptive cell transfer as personalized immunotherapy for human cancer

Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report

Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired

Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.

Chemotherapy-Refractory Diffuse Large B-Cell Lymphoma and Indolent B-Cell Malignancies Can Be Effectively Treated With Autologous T Cells Expressing an Anti-CD19 Chimeric Antigen Receptor

Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer

Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19

Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells

A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells

Adoptive immunotherapy for cancer: building on success

Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells

Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy

Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4.

T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis.

Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells

Gene transfer into humans--immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction

gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma

Phase 2 Trial of Single Agent Ipilimumab (Anti-CTLA-4) for Locally Advanced or Metastatic Pancreatic Adenocarcinoma

Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes

PD-1 identifies the patient-specific CD8⁺ tumor-reactive repertoire infiltrating human tumors

CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.

Adoptive cell therapy for the treatment of patients with metastatic melanoma

Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4

Exome sequencing identifies GRIN2A as frequently mutated in melanoma

Adoptive-cell-transfer therapy for the treatment of patients with cancer

Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer

Ipilimumab (anti-CTLA4 antibody) causes regression of metastatic renal cell cancer associated with enteritis and hypophysitis

Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients

CTLA-4 Blockade with Ipilimumab: Long-term Follow-up of 177 Patients with Metastatic Melanoma

Cutting edge: persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy

The natural history of initially untreated low-grade non-Hodgkin's lymphomas

Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer.

IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients