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List of works by Jaap Goudsmit

A Peptide-Based Plasmodium falciparum Circumsporozoite Assay To Test for Serum Antibody Responses to Pre-Erythrocyte Malaria Vaccines

scientific article published on March 16, 2011

A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.

scientific article published on 31 May 2018

A common solution to group 2 influenza virus neutralization

scientific article

A highly conserved neutralizing epitope on group 2 influenza A viruses

scientific article

A human monoclonal antibody cocktail as a novel component of rabies postexposure prophylaxis

scientific article published on January 2007

A proteomic approach to tumour target identification using phage display, affinity purification and mass spectrometry.

scientific article

A recombinant Bacille Calmette-Guérin construct expressing the Plasmodium falciparum circumsporozoite protein enhances dendritic cell activation and primes for circumsporozoite-specific memory cells in BALB/c mice

scientific article published on 6 October 2011

A recombinant adenovirus expressing immunodominant TB antigens can significantly enhance BCG-induced human immunity

scientific article published on January 30, 2012

A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen

scientific article

AIDS vaccines that allow HIV-1 to infect and escape immunologic control: a mathematic analysis of mass vaccination

scientific article

Ad35 and Ad26 Vaccine Vectors Induce Potent and Cross-Reactive Antibody and T-Cell Responses to Multiple Filovirus Species

scientific article published on December 6, 2012

Ad5:Ad48 hexon hypervariable region substitutions lead to toxicity and increased inflammatory responses following intravenous delivery

scientific article

Adenovirus 5 and 35 vectors expressing Plasmodium falciparum circumsporozoite surface protein elicit potent antigen-specific cellular IFN-gamma and antibody responses in mice

scientific article published on 16 April 2008

Adenovirus serotype 5 infects human dendritic cells via a coxsackievirus-adenovirus receptor-independent receptor pathway mediated by lactoferrin and DC-SIGN.

scientific article

Adenovirus types 5 and 35 seroprevalence in AIDS risk groups supports type 35 as a vaccine vector

scientific article published on May 2004

Adenovirus-specific immunity after immunization with an Ad5 HIV-1 vaccine candidate in humans

scientific article published on 20 July 2009

Affinity ranking of antibodies using flow cytometry: application in antibody phage display-based target discovery

scientific article

Age dependence of adenovirus-specific neutralizing antibody titers in individuals from sub-Saharan Africa

scientific article published on October 2006

An adenoviral type 5 vector carrying a type 35 fiber as a vaccine vehicle: DC targeting, cross neutralization, and immunogenicity

article by Olga J.A.E Ophorst et al published August 2004 in Vaccine

Antibody and T-cell responses to a virosomal adjuvanted H9N2 avian influenza vaccine: impact of distinct additional adjuvants.

scientific article

Antibody recognition of a highly conserved influenza virus epitope

scientific article

Antigen-driven CD4+ T cell and HIV-1 dynamics: residual viral replication under highly active antiretroviral therapy

scientific article published on December 1999

Broad cross-clade T-cell responses to gag in individuals infected with human immunodeficiency virus type 1 non-B clades (A to G): importance of HLA anchor residue conservation

scientific article

C-type lectin-like molecule-1: a novel myeloid cell surface marker associated with acute myeloid leukemia

scientific article

CTL escape and increased viremia irrespective of HIV-specific CD4+ T-helper responses in two HIV-infected individuals

article

Challenges in the search for an HIV vaccine

scientific article published in January 2004

Characterization of humoral and cellular immune responses elicited by a recombinant adenovirus serotype 26 HIV-1 Env vaccine in healthy adults (IPCAVD 001).

scientific article

Common structure of rare replication-deficient E1-positive particles in adenoviral vector batches

scientific article published on June 2004

Comparative seroprevalence and immunogenicity of six rare serotype recombinant adenovirus vaccine vectors from subgroups B and D

scientific article published on 28 February 2007

Comparison of an anti-rabies human monoclonal antibody combination with human polyclonal anti-rabies immune globulin

scientific article published on 6 February 2006

Cytomegalovirus and human herpesvirus 8 DNA detection in peripheral blood monocytic cells of AIDS patients: correlations with the presence of Kaposi's sarcoma and CMV disease

scientific article

Development of a nucleic acid sequence-based amplification assay that uses gag-based molecular beacons to distinguish between human immunodeficiency virus type 1 subtype C and C' infections in Ethiopia

scientific article published on April 2004

Differences in HIV Type 1 RNA Plasma Load Profile of Closely Related Cocirculating Ethiopian Subtype C Strains: C and C′

article

Differential antigen requirements for protection against systemic and intranasal vaccinia virus challenges in mice

scientific article published on 30 April 2008

EV01: a phase I trial in healthy HIV negative volunteers to evaluate a clade C HIV vaccine, NYVAC-C undertaken by the EuroVacc Consortium.

scientific article

Effect of neutralizing sera on factor x-mediated adenovirus serotype 5 gene transfer

scientific article published on 22 October 2008

Evaluation of a prime-boost vaccine schedule with distinct adenovirus vectors against malaria in rhesus monkeys

scientific article published on 15 August 2009

Evolutionary relationships among Astroviridae

scientific article (publication date: June 2002)

Expression and immunogenicity of the Plasmodium falciparum circumsporozoite protein: the role of GPI signal sequence

scientific article published on 7 November 2006

First-in-human evaluation of the safety and immunogenicity of a recombinant adenovirus serotype 26 HIV-1 Env vaccine (IPCAVD 001)

scientific article

Gene expression profile of AIDS-related Kaposi's sarcoma

scientific article published on March 18, 2003

Generation of a novel replication-incompetent adenoviral vector derived from human adenovirus type 49: manufacture on PER.C6 cells, tropism and immunogenicity

scientific article published on October 2006

Genetic immunization in the lung induces potent local and systemic immune responses

scientific article

HA Antibody-Mediated FcγRIIIa Activity Is Both Dependent on FcR Engagement and Interactions between HA and Sialic Acids

scientific article published on 29 September 2016

HIV type 1 C and C' subclusters based on long terminal repeat sequences in the Ethiopian type 1 subtype C epidemic

scientific article published in October 2003

Haemagglutinin quantification and identification of influenza A&B strains propagated in PER.C6 cells: a novel RP-HPLC method.

scientific article

Heterologous prime-boost vaccinations for poverty-related diseases: advantages and future prospects

scientific article published on May 2009

Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells

scientific article

Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity

scientific article published on 16 April 2006

High-level expression from two independent expression cassettes in replication-incompetent adenovirus type 35 vector

scientific article

Highly Conserved Protective Epitopes on Influenza B Viruses

scientific article

Human CD46-transgenic mice in studies involving replication-incompetent adenoviral type 35 vectors

scientific article

Human herpesvirus 8 load in matched serum and plasma samples of patients with AIDS-associated Kaposi's sarcoma

scientific article published on December 2003

Human monoclonal antibody as prophylaxis for SARS coronavirus infection in ferrets

scientific article published in June 2004

Human monoclonal antibody combination against SARS coronavirus: synergy and coverage of escape mutants

scientific article (publication date: July 2006)

Identification of Sequential Viral Escape Mutants Associated with Altered T-Cell Responses in a Human Immunodeficiency Virus Type 1-Infected Individual

scientific article published on December 1, 2003

Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer

scientific article published on 08 May 2009

Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys

scientific article published on 9 November 2008

Immune protection of nonhuman primates against Ebola virus with single low-dose adenovirus vectors encoding modified GPs

scientific article (publication date: June 2006)

Immunogenicity and safety of low dose virosomal adjuvanted influenza vaccine administered intradermally compared to intramuscular full dose administration

scientific article published on 10 April 2009

Immunogenicity of heterologous prime-boost regimens involving recombinant adenovirus serotype 11 (Ad11) and Ad35 vaccine vectors in the presence of anti-ad5 immunity

scientific article

Immunogenicity of heterologous recombinant adenovirus prime-boost vaccine regimens is enhanced by circumventing vector cross-reactivity

scientific article published on 11 October 2006

Immunogenicity of recombinant adenovirus serotype 35 vaccine in the presence of pre-existing anti-Ad5 immunity

scientific article published in May 2004

Immunogenicity of recombinant fiber-chimeric adenovirus serotype 35 vector-based vaccines in mice and rhesus monkeys

scientific article published on November 2005

Immunological memory to hyperphosphorylated tau in asymptomatic individuals

scientific article

Impact of recombinant adenovirus serotype 35 priming versus boosting of a Plasmodium falciparum protein: characterization of T- and B-cell responses to liver-stage antigen 1

scientific article published on 22 January 2008

In Vitro Neutralization Is Not Predictive of Prophylactic Efficacy of Broadly Neutralizing Monoclonal Antibodies CR6261 and CR9114 against Lethal H2 Influenza Virus Challenge in Mice

scientific article published on 18 October 2017

Increased immunogenicity of recombinant Ad35-based malaria vaccine through formulation with aluminium phosphate adjuvant

scientific article published on 29 June 2007

Induction of CAMEL/NY-ESO-ORF2-specific CD8+ T cells upon stimulation with dendritic cells infected with a modified Ad5 vector expressing a chimeric Ad5/35 fiber

scientific article published on March 2004

International seroepidemiology of adenovirus serotypes 5, 26, 35, and 48 in pediatric and adult populations

scientific article

Intradermal delivery of adenoviral type-35 vectors leads to high efficiency transduction of mature, CD8+ T cell-stimulating skin-emigrated dendritic cells

scientific article published in August 2006

Isolation and Characterization of Human Monoclonal Antibodies from Individuals Infected with West Nile Virus

scientific article

Lack of in vivo compartmentalization among HIV-1 infected naïve and memory CD4+ T cell subsets

scientific article published on 20 August 2009

Long-term survival of ancient DNA in Egypt: response to Zink and Nerlich (2003).

scientific article published on September 2005

Lots of peanut shells but no elephant

scientific article published in Nature

Low versus high CD4 cell count as starting point for introduction of antiretroviral treatment in resource-poor settings: a scenario-based analysis

scientific article published on February 1, 2003

Magnitude and phenotype of cellular immune responses elicited by recombinant adenovirus vectors and heterologous prime-boost regimens in rhesus monkeys

scientific article published on 12 March 2008

Mapping and analysis of West Nile virus-specific monoclonal antibodies: prospects for vaccine development

scientific article published on April 2007

Maternal antibodies protect offspring from severe influenza infection and do not lead to detectable interference with subsequent offspring immunization

scientific article

Matrix-M Adjuvated Seasonal Virosomal Influenza Vaccine Induces Partial Protection in Mice and Ferrets against Avian H5 and H7 Challenge

scientific article (publication date: 2015)

Matrix-M™ adjuvation broadens protection induced by seasonal trivalent virosomal influenza vaccine

scientific article

Mechanisms of hemagglutinin targeted influenza virus neutralization

scientific article

Meeting the immense need for HAART in resource-poor settings

scientific article published on October 16, 2003

Molecular and biological characterization of human monoclonal antibodies binding to the spike and nucleocapsid proteins of severe acute respiratory syndrome coronavirus

scientific article published in February 2005

Myeloid and plasmacytoid dendritic cells are susceptible to recombinant adenovirus vectors and stimulate polyfunctional memory T cell responses

scientific article published on August 2007

N-Linked Glycosylation of the HIV Type-1 gp120 Envelope Glycoprotein as a Major Determinant of CCR5 and CXCR4 Coreceptor Utilization

scientific article published in Journal of Biological Chemistry

Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354

scientific article published on October 18, 2010

Neutralizing antibodies and CD8+ T lymphocytes both contribute to immunity to adenovirus serotype 5 vaccine vectors

scientific article published on March 2004

Neutralizing antibodies to adenovirus serotype 5 vaccine vectors are directed primarily against the adenovirus hexon protein

scientific article published in June 2005

New class of monoclonal antibodies against severe influenza: prophylactic and therapeutic efficacy in ferrets

scientific article

Novel human monoclonal antibody combination effectively neutralizing natural rabies virus variants and individual in vitro escape mutants

scientific article

Novel rabies virus-neutralizing epitope recognized by human monoclonal antibody: fine mapping and escape mutant analysis

scientific article

Novel replication-incompetent vector derived from adenovirus type 11 (Ad11) for vaccination and gene therapy: low seroprevalence and non-cross-reactivity with Ad5.

scientific article published on December 2004

Obituary: Daniel Carleton Gajdusek (1923-2008).

scientific article

PER.C6(®) cells as a serum-free suspension cell platform for the production of high titer poliovirus: a potential low cost of goods option for world supply of inactivated poliovirus vaccine

scientific article

Phenotypic and genotypic comparisons of CCR5- and CXCR4-tropic human immunodeficiency virus type 1 biological clones isolated from subtype C-infected individuals

scientific article published on March 2004

Phylogenetic Relationships among the Species of the Genus Testudo (Testudines: Testudinidae) Inferred from Mitochondrial 12S rRNA Gene Sequences

scientific article (publication date: February 2002)

Plasma HIV-1 RNA to guide patient selection for antiretroviral therapy in resource-poor settings: efficiency related to active case finding

scientific article

Pre- and postexposure use of human monoclonal antibody against H5N1 and H1N1 influenza virus in mice: viable alternative to oseltamivir

scientific article published on December 2009

Prediction of residual time to AIDS and death based on markers and cofactors

scientific article published on April 2003

Primary HIV-1 subtype C infection in Ethiopia

scientific article published in August 2002

Primary effect of chemotherapy on the transcription profile of AIDS-related Kaposi's sarcoma

scientific article

Priming T-cell responses with recombinant measles vaccine vector in a heterologous prime-boost setting in non-human primates

scientific article published on June 22, 2012

Priming with an adenovirus 35-circumsporozoite protein (CS) vaccine followed by RTS,S/AS01B boosting significantly improves immunogenicity to Plasmodium falciparum CS compared to that with either malaria vaccine alone

scientific article published on 16 February 2007

Protection against H5N1 Influenza Virus Induced by Matrix-M Adjuvanted Seasonal Virosomal Vaccine in Mice Requires Both Antibodies and T Cells.

scientific article

Protection against H5N1 by multiple immunizations with seasonal influenza vaccine in mice is correlated with H5 cross-reactive antibodies

scientific article published on 7 February 2015

Protective efficacy of a single immunization of a chimeric adenovirus vector-based vaccine against simian immunodeficiency virus challenge in rhesus monkeys

scientific article published on 24 June 2009

Protective immune responses to a recombinant adenovirus type 35 tuberculosis vaccine in two mouse strains: CD4 and CD8 T-cell epitope mapping and role of gamma interferon

scientific article

Quantification of residual host cell DNA in adenoviral vectors produced on PER.C6 cells

scientific article

Quantifying Adenovirus-Neutralizing Antibodies by Luciferase Transgene Detection: Addressing Preexisting Immunity to Vaccine and Gene Therapy Vectors

scientific article published on November 1, 2003

RNA detection and subtype C assessment of HIV-1 in infants with diarrhea in Ethiopia

scientific article published on 20 May 2009

Rapid CD4+ T-lymphocyte depletion in rhesus monkeys infected with a simian-human immunodeficiency virus expressing the envelope glycoproteins of a primary dual-tropic Ethiopian Clade C HIV type 1 isolate

scientific article

Recent evolutionary history of human immunodeficiency virus type 1 subtype B: reconstruction of epidemic onset based on sequence distances to the common ancestor

scientific article published in May 2002

Recombinant adenovirus serotype 26 (Ad26) and Ad35 vaccine vectors bypass immunity to Ad5 and protect nonhuman primates against ebolavirus challenge

scientific article

Recombination of HIV type 1C (C'/C") in Ethiopia: possible link of EthHIV-1C' to subtype C sequences from the high-prevalence epidemics in India and Southern Africa

scientific article published on November 2003

Reduction of the HIV-1-infected T-cell reservoir by immune activation treatment is dose-dependent and restricted by the potency of antiretroviral drugs

scientific article published in April 2000

Replication-deficient human adenovirus type 35 vectors for gene transfer and vaccination: efficient human cell infection and bypass of preexisting adenovirus immunity

scientific article

Retrospective. Joep Lange (1954-2014).

scientific article

Risk factors for human herpesvirus 8 infection in a cohort of drug users in the Netherlands, 1985-1996.

scientific article published on 31 May 2002

Routine DNA analysis based on 12S rRNA gene sequencing as a tool in the management of captive primates

scientific article published in October 2000

Safety and efficacy in geese of a PER.C6-based inactivated West Nile virus vaccine

scientific article published on 15 October 2007

Stabilizing formulations for inhalable powders of an adenovirus 35-vectored tuberculosis (TB) vaccine (AERAS-402).

scientific article

Structural Basis for Recognition of a Unique Epitope by a Human Anti-tau Antibody

scientific article published on 11 October 2018

Surrogate Markers for Disease Progression in Treated HIV Infection

article

Surveillance technology for HIV-1 subtype C in Ethiopia: an env-based NASBA molecular beacon assay to discriminate between subcluster C and C'.

scientific article

T-helper 1 cells elicited by H5N1 vaccination predict seroprotection

scientific article

Temporal association patterns and dynamics of amyloid-β and tau in Alzheimer's disease

scientific article

The Th1 immune response to Plasmodium falciparum circumsporozoite protein is boosted by adenovirus vectors 35 and 26 with a homologous insert

scientific article

The human antibody repertoire specific for rabies virus glycoprotein as selected from immune libraries

scientific article published in July 2005

The incubation period of Alzheimer's disease and the timing of tau versus amyloid misfolding and spreading within the brain

scientific article published on 26 March 2016

The novel tuberculosis vaccine, AERAS-402, induces robust and polyfunctional CD4+ and CD8+ T cells in adults

scientific article

The potential of targeted antibody prophylaxis in SARS outbreak control: a mathematic analysis

scientific article published on 5 May 2006

The rate of epidemiological and virological changes during the transition from nascent to concentrated HIV epidemic stage in the former Soviet Union countries

scientific article published in February 2007

Timing of the Introduction into Ethiopia of Subcluster C′ of HIV Type 1 Subtype C

article

Towards an RTS,S-based, multi-stage, multi-antigen vaccine against falciparum malaria: progress at the Walter Reed Army Institute of Research.

scientific article

Trafficking of antigen-specific CD8+ T lymphocytes to mucosal surfaces following intramuscular vaccination

scientific article published in September 2008

Transient humoral protection against H5N1 challenge after seasonal influenza vaccination of humans

scientific article

Universal cellular tropism?

scientific article published in Nature

Universal influenza vaccine design: directing the antibody repertoire

Use of dried spots of whole blood, plasma, and mother's milk collected on filter paper for measurement of human immunodeficiency virus type 1 burden

scientific article published on 24 January 2007

Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys

scientific article published on 4 January 2012

Validation of the rapid fluorescent focus inhibition test for rabies virus-neutralizing antibodies in clinical samples

scientific article

Vascular endothelial growth factor levels in serum do not increase following HIV type 1 and HHV8 seroconversion and lack correlation with AIDS-related Kaposi's sarcoma

scientific article published in July 2002

Vector choice determines immunogenicity and potency of genetic vaccines against Angola Marburg virus in nonhuman primates

scientific article

Viral replication under combination antiretroviral therapy: a comparison of four different regimens

scientific article published in June 2002

rBCG induces strong antigen-specific T cell responses in rhesus macaques in a prime-boost setting with an adenovirus 35 tuberculosis vaccine vector

scientific article