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List of works by Stephen Elledge

A DNA Damage Response Screen Identifies RHINO, a 9-1-1 and TopBP1 Interacting Protein Required for ATR Signaling ⬇️

scientific article published on June 10, 2011

A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis

scientific article

A genetic screen for candidate tumor suppressors identifies REST

scientific article

A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair

scientific article

A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability

scientific article

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

scientific article

A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability

scientific article

A genome-wide genetic screen for host factors required for hepatitis C virus propagation

scientific article

A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation

scientific article published on 01 July 2019

A quantitative atlas of mitotic phosphorylation

scientific article

A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response

scientific article

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

scientific article

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

scientific article

Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities

scientific article

Autoreactivity and Exceptional CDR Plasticity (but Not Unusual Polyspecificity) Hinder Elicitation of the Anti-HIV Antibody 4E10

scientific article

Comprehensive viromewide antibody responses by systematic epitope scanning after hematopoietic cell transplantation

scientific article published on 11 June 2019

Control of ribonucleotide reductase localization through an anchoring mechanism involving Wtm1.

scientific article

DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1

scientific article

Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus

scientific article

Exit from exit: resetting the cell cycle through Amn1 inhibition of G protein signaling

scientific article

Germline-encoded amino acid–binding motifs drive immunodominant public antibody responses

scientific article published on 06 April 2023

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

scientific article

Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation

scientific article

IFITM3 inhibits influenza A virus infection by preventing cytosolic entry

scientific article published in October 2011

Identification of host proteins required for HIV infection through a functional genomic screen

scientific article

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

scientific article

Integrated proteogenetic analysis reveals the landscape of a mitochondrial-autophagosome synapse during PARK2-dependent mitophagy

scientific article published on 06 November 2019

Interspecies analysis of MYC targets identifies tRNA synthetases as mediators of growth and survival in MYC-overexpressing cells

scientific article published on 01 July 2019

MDC1 is a mediator of the mammalian DNA damage checkpoint

scientific article

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

scientific article

Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens

scientific article published on 01 November 2019

Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases

scientific article

Multiple tumor suppressor pathways negatively regulate telomerase

scientific article

NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control

scientific article

Ontogeny of recognition specificity and functionality for the broadly neutralizing anti-HIV antibody 4E10

scientific article published in September 2014

Origins of lymphatic and distant metastases in human colorectal cancer.

scientific article

Polyubiquitinated PCNA Recruits the ZRANB3 Translocase to Maintain Genomic Integrity after Replication Stress ⬇️

scientific article published on June 14, 2012

Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate ⬇️

scientific article published on May 31, 2011

Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

scientific article

Replication protein A-mediated recruitment and activation of Rad17 complexes ⬇️

scientific article published on November 6, 2003

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

scientific article (publication date: 15 December 2003)

Second-generation shRNA libraries covering the mouse and human genomes

scientific article

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

scientific article

Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction

scientific article

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

scientific article

Structure of the FANCI-FANCD2 Complex: Insights into the Fanconi Anemia DNA Repair Pathway

scientific article

Systematic analysis and nomenclature of mammalian F-box proteins

scientific article

Systematic characterization of mutations altering protein degradation in human cancers

scientific article published in 2021

Taking the brakes off telomerase

scientific article published on 21 July 2015

Temporal virus serological profiling of kidney graft recipients using VirScan

scientific article published on 13 May 2019

The DNA Damage Response: Making It Safe to Play with Knives ⬇️

scientific article (publication date: 22 October 2010)

The DNA damage response: ten years after

scientific article

The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus

scientific article

The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome

scientific article

The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart

scientific article

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

scientific article published on 24 August 2023

The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning

scientific article published on 10 February 2020

The tumor suppressor CYLD regulates entry into mitosis

scientific article

The ubiquitin-specific protease USP28 is required for MYC stability

scientific article

Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function

scientific article

Tissue-specificity in cancer: The rule, not the exception

scientific article

Turkey must end violent response to protests

scientific article

Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity

scientific article

WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity

scientific article

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