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List of works by Sydney Brenner

A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy

scientific article published on 24 August 2010

A compact cartilaginous fish model genome

article

A method for counting PCR template molecules with application to next-generation sequencing ⬇️

scientific article published on April 13, 2011

A novel molecular rotor facilitates detection of p53-DNA interactions using the Fluorescent Intercalator Displacement Assay

scientific article published in Scientific Reports

A suppressor mutation in the nematode acting on specific alleles of many genes

scientific article published in Nature

A survey of ancient conserved non-coding elements in the PAX6 locus reveals a landscape of interdigitated cis-regulatory archipelagos

scientific article

A trans-species missense SNP in Amhr2 is associated with sex determination in the tiger pufferfish, Takifugu rubripes (fugu).

scientific article

After the (draft) sequence

scientific article

An interview with... Sydney Brenner. Interview by Errol C. Friedberg

scientific article

Ancient noncoding elements conserved in the human genome

scientific article

Ancient vertebrate conserved noncoding elements have been evolving rapidly in teleost fishes

scientific article

Aptamer Selection by High-Throughput Sequencing and Informatic Analysis ⬇️

scientific article published on December 1, 2011

Basal vertebrates clarify the evolutionary history of ciliopathy-associated genes Tmem138 and Tmem216

scientific article

Changes in PDE4D isoforms in the hippocampus of a patient with advanced Alzheimer disease

scientific article published in March 2007

Characterization of a hypoxia-response element in the Epo locus of the pufferfish, Takifugu rubripes

scientific article

Characterization of the Runx gene family in a jawless vertebrate, the Japanese lamprey (Lethenteron japonicum).

scientific article

Characterization of the neurohypophysial hormone gene loci in elephant shark and the Japanese lamprey: origin of the vertebrate neurohypophysial hormone genes

scientific article

Characterization of the platelet-derived growth factor receptor alpha and c-kit genes in the pufferfish Fugu rubripes

scientific article published in October 2002

Chocolate habits of Nobel prizewinners

scientific article

Cloning and expression of the reverse transcriptase component of pufferfish (Fugu rubripes) telomerase

scientific article published on July 2005

Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors

scientific article

Compact intergenic regions of the pufferfish genome facilitate isolation of gene promoters: characterization of Fugu 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (fPapss2) gene promoter function in transgenic Xenopus

scientific article

Conservation of all three p53 family members and Mdm2 and Mdm4 in the cartilaginous fish

scientific article published on 15 December 2011

Conserved regulation of the lymphocyte-specific expression of lck in the Fugu and mammals

scientific article

Cyclostomes Lack Clustered Protocadherins

scientific article published on 5 November 2015

DNA-Encoded Compound Libraries as Open Source: A Powerful Pathway to New Drugs

scientific article published in January 2017

Early vertebrate chromosome duplications and the evolution of the neuropeptide Y receptor gene regions

scientific article

Elephant shark (Callorhinchus milii) provides insights into the evolution of Hox gene clusters in gnathostomes

scientific article published on 03 September 2009

Elephant shark genome provides unique insights into gnathostome evolution

scientific article (publication date: 9 January 2014)

Elephant shark sequence reveals unique insights into the evolutionary history of vertebrate genes: A comparative analysis of the protocadherin cluster

scholarly article

Encoded combinatorial chemistry

scientific article

Erratum: Corrigendum: Elephant shark genome provides unique insights into gnathostome evolution

scientific article published in Nature

Erythropoietin gene from a teleost fish, Fugu rubripes

scientific article published on 13 May 2004

Evidence for at least six Hox clusters in the Japanese lamprey (Lethenteron japonicum).

scientific article published on 16 September 2013

Evolution and functional characterisation of melanopsins in a deep-sea chimaera (elephant shark, Callorhinchus milii)

scientific article

Evolution of the neuropeptide Y family: New genes by chromosome duplications in early vertebrates and in teleost fishes

article

Expression of Wnt signaling skeletal development genes in the cartilaginous fish, elephant shark (Callorhinchus milii).

scientific article

Extensive expansion of the claudin gene family in the teleost fish, Fugu rubripes

scientific article published on 14 June 2004

Fred Sanger, Double Nobel Laureate: A Biography, by George G. Brownlee. 2014. Cambridge University Press

scientific article published in March 2016

Fugu and human sequence comparison identifies novel human genes and conserved non-coding sequences

scientific article (publication date: 10 July 2002)

Fugu genome analysis provides evidence for a whole-genome duplication early during the evolution of ray-finned fishes

scientific article published on 10 March 2004

Fugu genome does not contain mitochondrial pseudogenes

scientific article published on 4 January 2006

Genetic alterations in the tyrosine kinase transcriptome of human cancer cell lines

scientific article published on December 2007

Genetic basis of tetrodotoxin resistance in pufferfishes

scientific article

Highly conserved syntenic blocks at the vertebrate Hox loci and conserved regulatory elements within and outside Hox gene clusters

scholarly article

History of science. The revolution in the life sciences

scientific article

Hox gene clusters in the Indonesian coelacanth, Latimeria menadoensis

scientific article

Identification and analysis of additional copies of the platelet-derived growth factor receptor and colony stimulating factor 1 receptor genes in fugu

scientific article published in August 2002

Identification and characterization of novel mouse PDE4D isoforms: molecular cloning, subcellular distribution and detection of isoform-specific intracellular localization signals

scientific article published on 12 October 2007

In the beginning was the worm ...

scientific article published in June 2009

Inducible system in human hepatoma cell lines for hepatitis C virus production

scientific article published in November 2002

Integration of the genetic map and genome assembly of fugu facilitates insights into distinct features of genome evolution in teleosts and mammals

scientific article

Integrative Genome-wide Analysis Reveals Cooperative Regulation of Alternative Splicing by hnRNP Proteins ⬇️

scientific article published on February 23, 2012

Interview with Sydney Brenner by Soraya de Chadarevian

scientific article published on 23 February 2009

Into the blue: gene duplication and loss underlie color vision adaptations in a deep-sea chimaera, the elephant shark Callorhinchus milii

scientific article (publication date: March 2009)

Investigation of loss and gain of introns in the compact genomes of pufferfishes (Fugu and Tetraodon).

scientific article

Kinetochore structure, duplication, and distribution in mammalian cells: analysis by human autoantibodies from scleroderma patients ⬇️

scientific article published on October 1, 1981

Lampreys, the jawless vertebrates, contain only two ParaHox gene clusters

scientific article published on 7 August 2017

Large number of ultraconserved elements were already present in the jawed vertebrate ancestor

scientific article published on 3 December 2008

Life sentences: Ontology recapitulates philology

scientific article

Life sentences: elementary zenetics--do or dai.

scientific article

Loose Ends

1994 scholarly article by Sydney Brenner

Massively parallel signature sequencing (MPSS) as a tool for in-depth quantitative gene expression profiling in all organisms

scientific article

Medicine. The future of psychiatric research: genomes and neural circuits

scientific article

Mentioned in dispatches

scientific article published in Nature

Molecular analysis of the unc-54 myosin heavy-chain gene of Caenorhabditis elegans ⬇️

scientific article published on June 4, 1981

Molecular cloning of the pufferfish (Takifugu rubripes) Mx gene and functional characterization of its promoter

scientific article

Mouse transgenesis identifies conserved functional enhancers and cis-regulatory motif in the vertebrate LIM homeobox gene Lhx2 locus

scientific article

Mutations That Affect Dimer Formation and Helicase Activity of the Hepatitis C Virus Helicase

scientific article (publication date: 2001)

Nature's gift to science (Nobel lecture).

scientific article

Neuropeptide Y-family peptides and receptors in the elephant shark, Callorhinchus milii confirm gene duplications before the gnathostome radiation

scientific article

New directions in molecular biology

scientific article published in Nature

Nobel lecture. Nature's gift to science

scientific article published in October 2003

Novel vertebrate genes and putative regulatory elements identified at kidney disease and NR2E1/fierce loci

scientific article

Nuclear protein-coding genes support lungfish and not the coelacanth as the closest living relatives of land vertebrates

scientific article (publication date: 6 April 2004)

O sole mio!

scholarly article by Sydney Brenner

Obituary: Seymour Benzer (1921-2007).

scientific article

On the origin of SCPP genes

article

Origin and diversity of the SOX transcription factor gene family: genome-wide analysis in Fugu rubripes

scientific article

Parathyroid hormone gene family in a cartilaginous fish, the elephant shark (Callorhinchus milii).

scientific article

Physician-scientists are needed now more than ever.

scientific article

Pillars Article: Origin of antibody variation. Nature 1966. 211: 242-243.

scientific article

Pufferfish and zebrafish have five distinct NPY receptor subtypes, but have lost appetite receptors Y1 and Y5.

scientific article

Ray-fin fish tetraploidization gave rise to pufferfish duplicates of NPY and PYY, but zebrafish NPY duplicate was lost

scientific article

Reflex: intramolecular barcoding of long-range PCR products for sequencing multiple pooled DNAs ⬇️

scientific article published on April 10, 2013

Reflex™: a novel method to sequence barcoded long-range PCR products in a pooled population of hundreds of DNA samples.

scientific article published in October 2012

Replicating and reshaping DNA: a celebration of the jubilee of the double helix. Perspectives

scientific article

Retrospective. Frederick Sanger (1918-2013)

scientific article

Rhizobium sp. strain NGR234 possesses a remarkable number of secretion systems

scientific article

STAT4is a target of the hematopoietic zinc-finger transcription factor Ikaros in T cells

scholarly article by Wai-Ho Yap published in July 2005

Save your notes, drafts and printouts: today's work is tomorrow's history

scientific article published in Nature

Sequence and organization of coelacanth neurohypophysial hormone genes: evolutionary history of the vertebrate neurohypophysial hormone gene locus

scientific article

Sequences and consequences

scientific article published on January 2010

Sequencing and analysis of full-length cDNAs, 5'-ESTs and 3'-ESTs from a cartilaginous fish, the elephant shark (Callorhinchus milii)

scientific article (publication date: 2012)

Sequencing of Pax6 loci from the elephant shark reveals a family of Pax6 genes in vertebrate genomes, forged by ancient duplications and divergences

scientific article

Short Promoters in Viral Vectors Drive Selective Expression in Mammalian Inhibitory Neurons, but do not Restrict Activity to Specific Inhibitory Cell-Types

scientific article published on 9 November 2009

Summary statement of the Asilomar conference on recombinant DNA molecules ⬇️

scientific article published on June 1, 1975

Survey sequencing and comparative analysis of the elephant shark (Callorhinchus milii) genome

scientific article published in April 2007

Synthetic methods for the implementation of encoded combinatorial chemistry

article

TFCONES: a database of vertebrate transcription factor-encoding genes and their associated conserved noncoding elements

scientific article

Tetraodon genome analysis provides further evidence for whole-genome duplication in the ray-finned fish lineage

article

That lonesome grail: The Code of Codes: Scientific and Social Issues in the Human Genome Project

scientific article

The decipherment of Linear G

scientific article published in Nature

The fifth neurohypophysial hormone receptor is structurally related to the V2-type receptor but functionally similar to V1-type receptors

scientific article

The genetics of Caenorhabditis elegans

scientific article

The genome of the largest bony fish, ocean sunfish (Mola mola), provides insights into its fast growth rate

scientific article

The greatest satisfaction

scientific article published in Nature

The octopus genome and the evolution of cephalopod neural and morphological novelties

scientific article

The p53-Mdm2 interaction and the E3 ligase activity of Mdm2/Mdm4 are conserved from lampreys to humans

scientific article

The regulation of retina specific expression of rhodopsin gene in vertebrates

scientific article published in August 2003

The structure of the nervous system of the nematodeCaenorhabditis elegans ⬇️

scientific article published on November 12, 1986

The tale of the human genome

scientific article published in Nature

The worm's turn

scientific article

Transgenic rats reveal functional conservation of regulatory controls between the Fugu isotocin and rat oxytocin genes

scientific article

Turing centenary: Life's code script

scientific article

Twisted strands

scientific article published in Nature

Understanding the Human Brain ⬇️

scientific article published on November 4, 2011

Worms and science. An interview with Sydney Brenner, distinguished research professor at The Salk Institute, La Jolla, USA, and one of the winners of 2002 Nobel Prize for Physiology and Medicine

scientific article published in March 2003

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